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NIH Small Grants Linda Rueckert NEIU Office of Research Development

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Page 1: NIH Small Grants Linda Rueckert

NIH Small Grants

Linda RueckertNEIU Office of Research Development

Page 2: NIH Small Grants Linda Rueckert

This PowerPoint can be found at:

http://www.neiu.edu/~ordev

Page 3: NIH Small Grants Linda Rueckert

• Academic Research Enhancement Award (AREA; R15)

• Small grants (R03)

• NIH – Academic-Community Partnership Conference Series

• General information about NIH

Page 4: NIH Small Grants Linda Rueckert

Office of the DirectorOffice of the Director

National Instituteon Alcohol Abuseand Alcoholism

National Instituteon Alcohol Abuseand Alcoholism

National Instituteof Arthritis andMusculoskeletal

and Skin Diseases

National Instituteof Arthritis andMusculoskeletal

and Skin Diseases

National CancerInstitute

National CancerInstitute

National Instituteof Diabetes andDigestive and

Kidney Diseases

National Instituteof Diabetes andDigestive and

Kidney Diseases

National Instituteof Dental andCraniofacial

Research

National Instituteof Dental andCraniofacial

Research

National Instituteon Drug Abuse

National Instituteon Drug Abuse

National Instituteof Environmental Health Sciences

National Instituteof Environmental Health Sciences

National Instituteon Aging

National Instituteon Aging

National Instituteof Child Health

and HumanDevelopment

National Instituteof Child Health

and HumanDevelopment

National Institute onDeafness and Other

CommunicationDisorders

National Institute onDeafness and Other

CommunicationDisorders

National EyeInstitute

National EyeInstitute

National HumanGenome Research

Institute

National HumanGenome Research

Institute

National Heart,Lung, and Blood

Institute

National Heart,Lung, and Blood

Institute

National Instituteof Mental Health

National Instituteof Mental Health

National Instituteof NeurologicalDisorders and

Stroke

National Instituteof NeurologicalDisorders and

Stroke

National Instituteof General

Medical Sciences

National Instituteof General

Medical Sciences

National Instituteof Nursing Research

National Instituteof Nursing Research

National Libraryof Medicine

National Libraryof Medicine

Center forScientific

Review

Center forScientific

Review

Center forInformationTechnology

Center forInformationTechnology

National Centerfor Complementary

and AlternativeMedicine

National Centerfor Complementary

and AlternativeMedicine

National Instituteof Allergy and

Infectious Diseases

National Instituteof Allergy and

Infectious Diseases

FogartyInternational

Center

FogartyInternational

Center

National Centerfor ResearchResources

National Centerfor ResearchResources

National Institutes of HealthNational Institutes of Health

Clinical Center

Clinical Center

National Center on Minority Health andHealth Disparities

National Center on Minority Health andHealth Disparities

National Institute of Biomedical Imagingand Bioengineering

National Institute of Biomedical Imagingand Bioengineering

Page 5: NIH Small Grants Linda Rueckert

Academic Research Enhancement Award (AREA)

Page 6: NIH Small Grants Linda Rueckert

• Stimulate research at smaller schools that are not major recipients of NIH funding

• Support meritorious scientific research in the biomedical and behavioral sciences

• Expose students to meritorious research

Objectives of the AREA Program

Page 7: NIH Small Grants Linda Rueckert

• Up to $150,000 direct costs, plus applicable facilities and administrative (F&A) costs, expressed in modules of $25,000

• Up to 36 months of support awarded in a single budget/project period.

• Majority of research must be done at the eligible, applicant organization.

• Eligible for administrative supplements for under-represented minority students

Details: http://grants.nih.gov/grants/guide/pa-files/PA-06-042.html

Features of the AREA Program

Page 8: NIH Small Grants Linda Rueckert

Allocation Examples of $150,000 (in $25,000 modules)

Budget Period

First Year Second Year

Third Year

3-YearAward

$50,000 $50,000 $50,000

2-YearAward

$75,000 $75,000

Page 9: NIH Small Grants Linda Rueckert

Eligibility of College/University/School

• Domestic educational institution (public or private)

• Institution granting baccalaureate or higher level degree in a health-related science, such as biology, chemistry, microbiology, bioengineering, bioinformatics, computational biology, etc.

• In 4 or more of the last 7 years, no more than $3 Million in Total Costs (DC + F&A Costs) per year in NIH research support.

• Eligible at time of application and at time of award

Page 10: NIH Small Grants Linda Rueckert

Eligibility of College/University/School

• Eligibility based on entire College/University or on individual health-related Colleges with the University.

• Eligibility “formula” is two-tiered. Based on award data for last 7 fiscal years. Only determines ineligibility.

• Breaks out the following Colleges within a University: School/College of Medicine, Veterinary Medicine, Podiatry, Nutrition, Dentistry, Osteopathy, Pharmacy, Public Health, Optometry, Nursing, Chiropractic Medicine, and Allied Health. All NIH funding considered “Other Academic.”

Page 11: NIH Small Grants Linda Rueckert

Eligibility of the Principal Investigator

• Tied to eligibility of applicant organization• No application for the same project as a

pending AREA application in the same cycle• Eligible for only one AREA grant at a time• Must be registered in ERA Commons• Transfer of PI may cause ineligibility• Publications a plus but not required; expertise

may be demonstrated by preliminary data

Page 12: NIH Small Grants Linda Rueckert

Submitting an Application

• Electronic submission only • Modular format; use modular budget forms• Appendices permitted but limited• Three Receipt dates per year: February 25,

June 25, and October 25 (also AIDS-specific receipt dates)

• Due electronically by 5:00 p.m. local time.• New, Renewal, and Resubmissions permitted• 25 pages allowed for research plan• R15 applications are for research, not

training

Page 13: NIH Small Grants Linda Rueckert

AREA or R15 Application Timeline

Cycle I Cycle II Cycle III

Submissions Feb 25 June 25 Oct 25

Review Jun/Jul Oct/Nov Feb/Mar

Council Sept/Oct Jan/Feb May/Jun

Award Dec/Jan April /MayJuly/Aug

Page 14: NIH Small Grants Linda Rueckert

Review Criteria and Considerations

Standard NIH review criteria: significance, approach, innovation, investigator, environment.

Reviewers to comment in the Overall Evaluation on whether the application addresses the goals of the AREA program

Priority scores only; not percentiled

Page 15: NIH Small Grants Linda Rueckert

AREA Application & Award Data1999-2005

Year

# Competin

g

# Awards

Success Rate

$ Awarded ($1,000s)

1999 441 180 39.5 17,634

2000 501 125 25.0 19,871

2001 523 164 33.8 23,901

2002 500 188 38.8 26,277

2003 506 214 42.3 30,467

2004 619 195 31.2 37,633

2005 662 197 29.8 39,740

Page 16: NIH Small Grants Linda Rueckert

Small Research Grants (R03)

Page 17: NIH Small Grants Linda Rueckert

Small Research Grants (R03)• Up to $50K per year for 2

Years (plus F&A)

• Some institutes may have different restrictions (e.g. new investigators only)

Page 18: NIH Small Grants Linda Rueckert

Small Research Grants (R03) cont’d• Electronic submission

through grants.gov• Receipt dates: Feb. 16,

June 16, Oct. 16• Research plan may not

exceed 10 pages• Preliminary data not

required

More info: http://grants.nih.gov/grants/guide/pa-files/PA-06-180.html

Page 19: NIH Small Grants Linda Rueckert

Academic-Community Partnership Conference Series

Page 20: NIH Small Grants Linda Rueckert

Academic-Community Partnership Conference Series• Limited to EARDA institutions.

• Conduct health-disparities related workshops and meetings.

• Topics: violence reduction, obesity, health literacy, information dissemination, infant mortality, fibroid tumors.

• Academics and community members meet to develop a research agenda.

Page 21: NIH Small Grants Linda Rueckert

Academic-Community Partnership Conference Series cont’d

• Up to $30,000 per year.

• Up to 3 years.

• Develop a proposal for a larger grant to carry out the research.

• Letter of intent receipt date: May 17

• Application receipt date: June 17

More info: http://grants.nih.gov/grants/guide/pa-files/PAR-08-106.html

Page 22: NIH Small Grants Linda Rueckert

NIH – General Information• Types of Funding

Opportunity Announcements

• Organization of NIH• Application Process• Proposal writing tips

Page 23: NIH Small Grants Linda Rueckert

National Institutes of Health FOAs

• “Parent” FOAs• Program Announcements (PAs)• Requests for Application (RFAs)• All posted in the NIH Guide for Grants and

Contracts (http://grants2.nih.gov/grants/guide/)

Page 24: NIH Small Grants Linda Rueckert

NIH Parent FOAs

• Generic• Can be on any health-related

topic• Ongoing receipt dates• Examples: R03 (small grants);

R15; R01

Page 25: NIH Small Grants Linda Rueckert

Program Announcement (PA)

• More specific than parents• Same receipt dates• Same review process• “Fit” to PA not part of review• No funds set aside• Can revise and resubmit

Page 26: NIH Small Grants Linda Rueckert

NIH Request for Applications

• More specific• Funds set aside• Success rate depends on

number of appls• Separate review with specific

criteria• One time only - no

resubmission• May have different receipt date

Page 27: NIH Small Grants Linda Rueckert

NIH Organization

Page 28: NIH Small Grants Linda Rueckert

The NIH Extramural Team

ProgramStaff

ReviewStaff

GrantsManagement

Page 29: NIH Small Grants Linda Rueckert

Office of the DirectorOffice of the Director

National Instituteon Alcohol Abuseand Alcoholism

National Instituteon Alcohol Abuseand Alcoholism

National Instituteof Arthritis andMusculoskeletal

and Skin Diseases

National Instituteof Arthritis andMusculoskeletal

and Skin Diseases

National CancerInstitute

National CancerInstitute

National Instituteof Diabetes andDigestive and

Kidney Diseases

National Instituteof Diabetes andDigestive and

Kidney Diseases

National Instituteof Dental andCraniofacial

Research

National Instituteof Dental andCraniofacial

Research

National Instituteon Drug Abuse

National Instituteon Drug Abuse

National Instituteof Environmental Health Sciences

National Instituteof Environmental Health Sciences

National Instituteon Aging

National Instituteon Aging

National Instituteof Child Health

and HumanDevelopment

National Instituteof Child Health

and HumanDevelopment

National Institute onDeafness and Other

CommunicationDisorders

National Institute onDeafness and Other

CommunicationDisorders

National EyeInstitute

National EyeInstitute

National HumanGenome Research

Institute

National HumanGenome Research

Institute

National Heart,Lung, and Blood

Institute

National Heart,Lung, and Blood

Institute

National Instituteof Mental Health

National Instituteof Mental Health

National Instituteof NeurologicalDisorders and

Stroke

National Instituteof NeurologicalDisorders and

Stroke

National Instituteof General

Medical Sciences

National Instituteof General

Medical Sciences

National Instituteof Nursing Research

National Instituteof Nursing Research

National Libraryof Medicine

National Libraryof Medicine

Center forScientific

Review

Center forScientific

Review

Center forInformationTechnology

Center forInformationTechnology

National Centerfor Complementary

and AlternativeMedicine

National Centerfor Complementary

and AlternativeMedicine

National Instituteof Allergy and

Infectious Diseases

National Instituteof Allergy and

Infectious Diseases

FogartyInternational

Center

FogartyInternational

Center

National Centerfor ResearchResources

National Centerfor ResearchResources

National Institutes of HealthNational Institutes of Health

Clinical Center

Clinical Center

National Center on Minority Health andHealth Disparities

National Center on Minority Health andHealth Disparities

National Institute of Biomedical Imagingand Bioengineering

National Institute of Biomedical Imagingand Bioengineering

Page 30: NIH Small Grants Linda Rueckert

NIH Institutes and Centers (ICs) with ExtramuralFunding Authority

• National Cancer Institute (NCI)• National Eye Institute (NEI)• National Heart, Lung, and Blood Institute (

NHLBI)• National Human Genome Research

Institute (NHGRI)• National Institute on Aging (NIA)• National Institute on Alcohol Abuse and

Alcoholism (NIAAA)• National Institute of Allergy and Infectious

Diseases (NIAID)• National Institute of Arthritis and

Musculoskeletal and Skin Diseases (NIAMS)

• National Institute of Biomedical Imaging and Bioengineering (NIBIB)

• National Institute of Child Health and Human Development (NICHD)

• National Institute on Deafness and Other Communication Disorders (NIDCD)

• National Institute of Dental and Craniofacial Research (NIDCR)

• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

• National Institute on Drug Abuse (NIDA)• National Institute of Environmental

Health Sciences (NIEHS)• National Institute of General Medical

Sciences (NIGMS)• National Institute of Mental Health

(NIMH)• National Institute of Neurological

Disorders and Stroke (NINDS)• National Institute of Nursing Research

(NINR)• National Library of Medicine (NLM)• Fogarty International Center (FIC)• National Center for Complementary and

Alternative Medicine (NCCAM)• National Center on Minority Health and

Health Disparities (NCMHD)• National Center for Research Resources

(NCRR)

Page 31: NIH Small Grants Linda Rueckert

NICHD Organizational Chart• Center for Developmental Biology and

Perinatal Medicine (CDBPM)• Center for Population Research

(CPR)• National Center for Medical

Rehabilitation Research (NCMRR) • Center for Research for Mothers

and Children (CRMC)

Page 32: NIH Small Grants Linda Rueckert

Center for Research for Mothers and Children (CRMC)

• The Center for Research for Mothers and Children (CRMC), serves as the principal NIH source of support for research and research training in maternal and child health. CRMC-supported scientists are advancing fundamental and clinical knowledge concerning maternal health and child development problems such as low birth weight, mental retardation and developmental disabilities, specific learning disabilities, congenital and genetic defects, growth retardation, HIV, and other congenital infections and diseases. The major goals of the Center are to ensure that mothers and families are healthy, and that all babies are born healthy and will reach adulthood and achieve their full potential.

• Endocrinology, Nutrition and Growth Branch (ENG)

• Child Development and Behavior Branch (CDB)

• Pediatric, Adolescent and Maternal AIDS Branch (PAMA)

• Obstetric and Pediatric Pharmacology Branch (OPP)

Page 33: NIH Small Grants Linda Rueckert

NIH Application Process

Page 34: NIH Small Grants Linda Rueckert

• Identify research question with clear aims and hypotheses

• Identify potential collaborators

• Contact program staff from NICHD

• Send brief concept paper identifying significance, aims, hypotheses, methods, sample, analysis, and impact

Page 35: NIH Small Grants Linda Rueckert

Program Officials’ role in Application Development

• Develop concepts for Institute/Center Initiatives

• Communicate goals of Institute/Center Initiatives

• Advise applicants on funding mechanisms • Provide grant writing advice and study

section information • Advises on application procedures,

requirements and general grant policy

Page 36: NIH Small Grants Linda Rueckert

Over 80,000 applications are received each year by CSR, which checks for compliance with NIH policies and then makes 2 assignments:• Program assignment to Institute/Center (IC) for

possible funding consideration• Review assignment to a Scientific Review Group

(SRG)

Page 37: NIH Small Grants Linda Rueckert

Referral for Review

• Assignments are made to CSR Study Section or to an Institute/Center Review Group – Topics addressed in the

application– Areas of expertise in the Study

Section– Certain kinds of applications

always go to an Institute/Center for review

Page 38: NIH Small Grants Linda Rueckert

Review Criteria

• Significance• Approach• Innovation• Investigators• Environment

Plus HS Protection & Inclusion of Gender,

Minority and Children

Page 39: NIH Small Grants Linda Rueckert

Grant Application Cycle

National Institutes of HealthNational Institutes of Health

Center for Scientific Review(Receipt & Referral)

Center for Scientific Review(Receipt & Referral)

Scientific Review GroupScientific Review Group

Institute/CenterInstitute/Center

Advisory Councils and BoardsAdvisory Councils and Boards

Institute DirectorInstitute Director

ApplicantInstitution

ApplicantInstitution

PrincipalInvestigator

PrincipalInvestigator

Submits Application

Receives AwardMakes Assurances Allocates Funds

Initiates Research Idea

Conducts Research

Makes Funding Decision

Performs Second-Level Review

Evaluates for Program Relevance

Reviews for Scientific Merit

Accepts & Assigns to IC & SRG

Page 40: NIH Small Grants Linda Rueckert

Timeline: New Applications

ReceiptDate

February 1

June 1

October 1

ScientificReview

July

October

March

CouncilReview

October

February

June

AwardDate

December

April

July

Page 41: NIH Small Grants Linda Rueckert

• Carefully read instructions before starting• Know and refer to the literature of your area• State strong rationale of proposed

investigation• Include well-designed tables and figures• Present an organized, lucid write-up• Obtain pre-review from faculty at your

institution• Never assume reviewers “will know what you

mean.”

Proposal Writing Tips

Page 42: NIH Small Grants Linda Rueckert

Grantsmanship

• Remember, reviewers have a day job• Project a realistic amount of work• Be sure you have found key references• Know your reviewers/peers• Minimize typographical errors

Page 43: NIH Small Grants Linda Rueckert

Concerns Raised by Reviewers

• Lack of new or original ideas• Absence of an acceptable scientific rationale,

uncritical approach• Lack of experience in the essential methodology• Questionable reasoning in experimental

approach• Diffuse, superficial, or unfocused research plan,

insufficient experimental detail• Lack of knowledge of published relevant work• Unrealistic amount of work• Uncertainty concerning future directions