november 2016 - perkinelmer · 2016-11-08 · safe harbor statement •this document and/or...
TRANSCRIPT
© 2015 PerkinElmer
HUMAN HEALTH • ENVIRONMENTAL HEALTH
Collaboration to Insight
November 2016
Safe Harbor Statement
• This document and/or presentation shows current
intentions regarding product features, behavior, schedules
and support; these intentions may change without notice
as we respond to customer requirements.
• Any unreleased products, services or features referenced
herein are not currently available and may not be delivered
on time or at all. Customers who purchase PerkinElmer
informatics applications should make their purchase
decisions based upon products, features, and services that
are currently available.
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Agenda
• Themes
• Workflow Solutions
• Getting Answers: Virtualized Data Integration and Analytics
• Preview of new application for Structure Activity Relationship
analysis
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Forces at Work in our Industry
Key Market Trends (2010-Present)
• Complexity of customer questions increasing
• More data intensive assay platforms
• Big data technologies required to keep up with science
• Rapid cloud and mobile adoption
• Increasing R&D externalization and collaboration
• Need Informatics solutions to complete customer scientific workflow
• Informatics increasingly important to
differentiate instrument platforms
• Customers want more complete solutions to help answer their complex questions
Worldwide data volume doubles every two years. By
2020, it will have grown to 40 zettabytes –a 50x increase
within 10 years
Implications for our strategy…
Modularity
Security
Performance
Cloud
ARCHITECTURE
Data Visualization
Data Integration
Advanced Statistics
Machine Learning
ANALYTICS
Collaboration
Compliance
Data Management
Workflow
CORE
CAPABILITIES
Life Science
Physical Science
Pharma Science
Clinical Development
SCIENCE
Informatics Innovation @ The New Speed of Science
Innovation Lab
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An Evolution of Needs
Capturing Flexible Content
• Documenting The Experiment
• All file types
• Signing, witnessing workflows
• Text string searching
Organizing the Workflow
• Guiding data capture into specific fields
• Increasing consistency
• Guided personal workflows
Collaboration
• Provide communication between groups
• Sample creation
• Returning reports
Data analytics
• Mining and visualizing data from across the company
• Data compiled from multiple experiments
These intentions may change without notice as we respond to customer requirements.
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Strategy to Support Fundamental Research Workflows
Collaborate
Make
Test Decide
Research Workflow Suite
• Cloud enabled
• Integrate workflows
Decision Support
Use Cases
• SAR
• Other
Technology
• Search
• Analytics
What gets made
• Compounds
• Biologics
• Formulations
• Sample Prep
What gets tested
• Proteins
• Cells
• Animals
• Analytical samples
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Perk
inE
lmer
Pla
tform
Core Configurable System Components
Collaboration
Data Management
Sample Workflow
Analytics
Flexible Organization
Security
Form Builder
Flexible Test Results
Test Requests
Sample Management
Spotfire
NoSQL Data Warehousing
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ELN, Search and the Larger Data Sphere Intersection of research informatics, search and business intelligence
Data In
• Structuring Data
• Ingesting Data
Data Out
• Mining and visualization
• Analytics
Index Integration & Enrichment
LIMS Clinical Documents CDS Data Structures
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Sample DMPK and Bioanalytical Workflow
User Roles
SD Create PK
Protocol
Scientist Create
PK Studies
Browse by
Protocols &
Studies
Formulation
Study Folder
InLife Study
Folder
PK BA Study
Folder
Generate PK
Report and
Summit for QC
Submit to CRO
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Organizational Framework
PK scientists are organized into groups
Study Design users direct the entire DMPK studies
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Formulation Initiation
In Formulation Study Folder, to prepare formulation, information of dose groups
and test articles can be loaded from PK protocol
Load dose groups
Load test
articles
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In vivo samples collected
Any entry with completed data will light as green.
Time automatically entered.
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Final Data from Bioanalytical Collated
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Bench level analytics for Formulation Scientists
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Process Optimization Example
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Project management
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Data to Insight Framework
Flexibility
Agility
Perception
Capabilities Function
Advanced Analytics Mathematical Perception
Data Discovery Visual Perception
Agile Science Assay Result Storage
Agile Warehousing Structured & Unstructured Data
Collaboration Document & Share
Storage Backend flexibility
Cloud Flexibility, Scalability & Externalization
Mobile Mobile Access
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A system that gives you answers
SAP
Scientific
Assays
Instruments
Process
Control
Stability
E-Notebook
Forms
Structured Data
Workflow
NoSQL
Portals
Fileshares
Document Stores Documentum
Opentext
Pe
rkin
Elm
er
Sig
na
ls™
Pe
rsp
ec
tive
s
ANSWERS
Analytics
DATA SOURCES TECHNOLOGIES
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Virtual data aggregation and analytics
• ELN that structures data
• Analytics across systems
• Integrated text analytics
• Scientific data visualization
• Integrated design of
experiment
• Instrument data processing
• Natural multivariate statistics
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Proposed Analytics Architecture
Analytical &
CDS Data
PerkinElmer Signals
Oth
er
An
aly
tica
l
Data
ELN Data
Formulations
ELN Analytical
Tests
Other
Experiments
Other Systems? SpotFire
Analytical Data
Screening
Data
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Real-time query directly in Spotfire
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2 3
1. Type-ahead to filter project list.
2. Select the project(s) of interest.
3. Signals for SAR provides real-time feedback about how
many compounds are found.
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Data download to customizable SAR Tables
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Easily configured SAR analysis
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Point-and-click chemically intelligent histograms
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Rotate-able 3D scatter plot to explore chemical space
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Point-and-click SAR cross-table saves hours of work
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Analyze – Compound series
1. Input substructures and
have the found
compounds “tagged” as
compound series.
2. Those compound series
tags then appear as axis
options and filter options
in the other windows.
Thank you
VP, Strategy & Commercial
Michael Swartz
Director, Portfolio Strategy
Joshua Bond