november 29 (thu.)

14

Program

Novem

ber 29

November 29 (Thu.)Session 1

13:00-15:00 Ito Hall

Chairs: Chiara Romagnani ( German Rheumatism Research Center, A Leibniz Institute, Berlin, Germany)

Hiroshi Ohno ( Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Madical Sciences, Kanagawa, Japan)

〈Chairs' Overview〉S1-1 Chiara Romagnani

〈Invited Talk〉S1-2 Innate Lymphoid Cells in Chronic Inflammatory Diseases

Andreas Ramming

S1-3 Role of Group 2 Innate Lymphoid Cells in Idiopathic Interstitial PneumoniasKazuyo Moro

〈Short Talks from Poster〉S1-4 Emergence of ILC2 Subtype Heterogeneity during Helminth Infection

Patrice Zeis, Mi Lian, Xiying Fan, Cornelia Hilpert, Rebecca Gentek, Marc Bajenoff, Alexander Rudensky, David Voehringer, Georg Gasteiger, Dominic Grün

S1-5 ILC3s Mediate Early Protection against Mycobaterium TuberculosisAmanda Lee Ardain, Racquel Domingo-Gonzalez, Shibali Das, Samuel W Kazer, Tyler Ulland, Alex K Shalek, Henrik N Kloverpris, Marco Colonna, Shabaana A Khader, Alasdair Leslie

S1-6 ILC3-like NK Cells Promote Tumor Growth in Head and Neck Squamous Cell CarcinomaDavid C Mundy, Uriel Y Moreno-Nieves, Serena C Chang, Saumyaa Mittal, June Ho Shin, John B Sunwoo

S1-7 Infants Breastfed with Milk Containing High Long-chain Saturated Fatty Acids (LCSFA) Is Associated with Risk of Atopic Dermatitis Development via an Involvement of ILCsMasamoto Kanno, Weng Sheng Kong, Naohiro Tsuyama, Naoki Shimojo, Hiroko Inoue, Yun Guo

15

ProgramN

ovember 29

Session 215:30-17:15 Ito Hall

Chairs: Andrew N J McKenzie ( Medical Research Council Laboratory of Molecular Biology, Cambridge, UK)

Shinichiro Sawa ( Division of Developmental Immunology, Institute for Genetic Medicine, Hokkaido University, Hokkaido, Japan)

〈Chairs' Overview〉S2-1 Andrew N J McKenzie

S2-2 Adipose-derived Stromal Cells Provide a Niche for ILC2-driven Type-2 Immune HomeostasisBatika M J Rana, Jillian L Barlow, Jennifer A Walker, Clare S Hardman, E Suzanne Cohen, Ian C Scott, Matthew A Sleeman, Chiamaka I Chidomere, Sara Cruz Migoni, Jorge Caamano, Helle F Jorgensen, Stefania Carrobio, Antoni Vidal-Puig, Paul J Bryce, Andrew N J McKenzie

〈Invited Talk〉S2-3 Regulation of NKT Cell Development and Function

Florian Winau

〈Short Talks from Poster〉S2-4 Characterization of ILC Precursor Potential in Multi-transcription Factor

Reporter Mouse ModelsDylan E Cherrier, Wei Xu, Sylvestre Chea, Christian Vosshenrich, Nicolas Serafini, Maxime Petit, Rachel Golub, James P Di Santo

S2-5 A Point Mutation in the Ncr1 Signal Peptide Impairs the Development of Innate Lymphoid Cell SubsetsFrancisca Almeida, Sara Tognarelli, Andrew Kueh, Yang Liao, Emilie Narni-Mancinelli, Justine Galluso, Marco Herold, Thierry Walzer, Sophie Ugolini, Wei Shi, Eric Vivier, Evelyn Ullrich, Gabrielle Belz

S2-6 Insulin-like Growth Factor 1 Regulates a Pulmonary Niche Promoting Type 3 Innate Lymphoid Cell Development Necessary for Protection against Pneumonia in the NewbornHitesh Deshmukh, Ian Lang, Jerilyn Gray, Karishma Ponkshe, Aishwarya Varma

S2-7 Sin1 Regulates Group 2 Innate Lymphoid Cell (ILC2) Maintenance and FunctionHongzhi Liu, Yanyun Hao, Jingjing Qi, Liang Li, Xinxing Ouyang, Lei Chen, Lei Shen, Bing Su

16

Program

Novem

ber 29

Keynote Lecture17:30-18:15 Ito Hall

Chair: Shigeo Koyasu ( Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan)

KL-1 Overcoming Inflammatory Diseases and Cancer: Characterization of Damage-associated Molecular PatternsTadatsugu Taniguchi ( Department of Molecular Immunology, Institute of Industrial Science, The

University of Tokyo, Tokyo, Japan)

17

ProgramN

ovember 30

November 30 (Fri.)Session 3

9:00-10:30 Ito Hall

Chairs: Eric Vivier ( Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université – CNRS, Marseille, France)

Susumu Nakae ( Japan Frontier Research Initiative, Institute of Medical Science, The University of Tokyo, Tokyo, Japan)

〈Chairs' Overview〉S3-1 Eric Vivier

S3-2 Definition of Natural Killer Cell Heterogeneity in Human and Mouse by High-throughput Single-cell RNA SequencingAdeline M Crinier, Pierre Milpied, Bertrand Escalière, Christelle Piperoglou, Justine Galluso, Anaïs Balsamo, Lionel Spinelli, Inaki Cervera-Marzal, Mikaël Ebbo, Sébastien Jaeger, Emilie Bollon, Sami Hamed, Jean Hardwigsen, Frédéric Vély, Emilie Narni-Mancinelli, Eric Vivier

〈Invited Talk〉S3-3 Transcriptional Delineation of Human ILCs at the Single-cell Level

Jenny Mjösberg

〈Short Talks from Poster〉S3-4 Single Cell RNA Sequencing Analysis of Lineage low Lung Cells from

RORα Lineage Tracer Mice Reveals Heterogeneity and Potential Immune Regulatory Capacity of Group 2 Innate Lymphoid CellsMaryam Ghaedi, Zi Yi Shen, Lisa Wei, Itziar Martinez-Gonzalez, Marco A Marra, Fumio Takei

S3-5 Innate Lymphoid Cells and Interleukin-22: Functional Analysis in ZebrafishPedro Pablo Hernandez, Paulina Strzelecka, Emmanouil Athanasiadis, Jean-Pierre Levraud, Ana Cvejic

S3-6 Tracking the Fate of Antigen-specific Versus Cytokine-activated Natural Killer Cells after Cytomegalovirus InfectionTsukasa Nabekura, Lewis L Lanier

18

Program

Novem

ber 30


Chairs: Sachiko Miyake ( Department of Immunology, Juntendo University Faculty of Medicine, Tokyo, Japan)

Hiroshi Watarai ( Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan)

〈Chairs' Overview〉S4-1 Sachiko Miyake

〈Invited Talk〉S4-2 The γδ TCR: Combining Innate and Adaptive Immunity in a Single

ReceptorAdrian Hayday

〈Long Talk from Poster〉S4-3 Quiescent Tissue-resident ILCs Give Rise to a Spectrum of ILC2 and ILC3

Populations in Response to IL-23 StimulationSamantha J Riesenfeld, Piotr Bielecki, Monika Kowalczyk, Carolina Maria Amezcua Vesely, Abigail Jarret, Ruaidhri Jackson, Will Bailis, Aviv Regev, Richard A Flavell

〈Short Talks from Poster〉S4-4 Transdifferentiated Type 2 Innate Lymphoid Cells Are Important Regulators

of Neutrophilia in Cystic FibrosisSuzanne Bal, Korneliusz Golebski, Xavier Ros, Sophie van Tol, Maho Nagasawa, Balthasar Heesters, Hajar Aglmous, Chantal Kradolfer, Cornelis van Drunen, Wytske Fokkens, Hergen Spits

S4-5 Functional Plasticity of ILC2s to ILC3s Is Determined by the Tissue MicroenvironmentJan-Eric Turner, Martina Becker, Ann-Christin Gnirck, Malte Wunderlich, Constantin Rickassel, Tingting Xiong, Georg Gasteiger

19

ProgramN

ovember 30

Luncheon Seminar 112:30-13:15 Ito Hall

Chair: Koichiro Asano ( Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Kanagawa, Japan)

LS-1 Group 2 Innate Lymphoid Cells in the Airways of Patients with Severe AsthmaParameswaran Nair ( McMaster University, ON, Canada)

Sponsored by AstraZeneka K.K.


Chairs: Marco Colonna ( Department of Pathology and Immunology, Washington University School of Medicine, MO, USA)

Kazuko Shibuya ( Department of Immunology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan)

〈Chairs' Overview〉S5-1 Marco Colonna

S5-2 The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid CellsJennifer Kaoru Bando, Susan Gilfillan, Christina Song, Keely G McDonald, Stanley C-C Huang, Rodney D Newberry, Yasuhiro Kobayashi, David SJ Allan, James R Carlyle, Marina Cella, Marco Colonna

〈Invited Talk〉S5-3 ILC1 Confer Early Host Protection at Initial Sites of Viral Infection

Orr-El Weizman, Nicholas M Adams, Iona Schuster, Chirag Krishna, Yuri Pritykin, Colleen Lau, Mariapia A Degli-Esposti, Christina S Leslie, Joseph C Sun, Timothy E O’Sullivan

S5-4 Regulation of ILC Function and IdentityDavid R Withers, Remi B Fiancette, Claire M Willis, Matthew R Hepworth

〈Short Talks from Poster〉S5-5 Runx Proteins Prevent Group 2 Innate Lymphoid Cells from Exhaustion in

Allergic InflammationTakashi Ebihara, Chizuko Miyamoto, Satoshi Kojo, Motoi Yamashita, Kazuyo Moro, Georges Lacaud, Ichiro Taniuchi

S5-6 Group 3 Innate Lymphoid Cells Amplify Hippo-Yap1 Signaling Pathways Required for Small Intestinal RepairTom Cupedo, Monica Romera Hernandez, Patricia Aparicio Domingo, Natalie Papazian, Julien J Karrich, Ferry Cornelissen, Remco M Hoogenboezem, Janneke N Samsom

20

Program

Novem

ber 30

S5-7 Group 3 Innate Lymphoid Cells Regulate the Intestinal Mucosal Adaptive Immune Responses through ID2-dependent PathwayYiping Li, Wenyan Wang, Xiaohuan Guo


Chairs: Gregory F Sonnenberg ( Jill Roberts Institute for Research in Inflammatory Bowel Disease, Department of Medicine, Gastroenterology Division, Weill Cornell Medicine, Cornell University, NY, USA)

Naoki Shimojo ( Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan)

〈Chairs' Overview〉S6-1 Gregory F Sonnenberg

S6-2 Metabolic Control of Pathologic Versus Protective Functions of Innate Lymphoid Cells at Barrier SitesLaurel Monticelli, Tiffany Huang, Gregory Putzel, David Artis

〈Invited Talk〉S6-3 Neuroendocrine Regulation of Innate Lymphoid Cell Function

Sophie Ugolini

〈Short Talks from Poster〉S6-4 Oxysterol Sensing through the Receptor GPR183 Is Essential for the

Migration and Lymphoid Tissue-inducing Function of Innate Lymphoid Cells in the IntestineTim Willinger

S6-5 Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune CircuitJakob von Moltke, Marija S Nadjsombati, John W McGinty, Miranda R Lyons-Cohen, James B Jaffe, Lucian DiPeso, Christoph Schneider, Corey N Miller, Joshua L Pollack, GA Nagana Gowda, Mary F Fontana, David J Erle, Mark S Anderson, Richard M Locksley, Daniel Raftery

S6-6 Lipid Droplet Formation Fuels Pathogenic ILC2 Responses in Airway InflammationChristoph Wilhelm, Schekufe Kharabi, Fotios Karagiannis, Vanessa Schmitt, Alexander Kazakov, Surendar Jayagopi

21

ProgramN

ovember 30

Evening Seminar on Human ILCs18:00-18:50 Ito Hall

Studies on Human ILCs toward Understanding DiseasesChair: Takanori Kanai ( Division of Gastroenterology & Hepatology, Department of Internal Medicine,

Keio University School of Medicine, Tokyo, Japan)

ES-1 New Transitional Populations of Human ILCHergen Spits ( Department of Experimental Immunology Amsterdam UMC, University of Amsterdam,

Amsterdam Infection & Immunity Institute, Amsterdam, The Netherlands)

ES-2 Clonal Dissection of Human ILC DifferentiationJames Di Santo ( Department of Immunology, Institute Pasteur, Paris, France)

Sponsored by Sanofi K.K.

22

Program

Decem

ber 1

December 1 (Sat.)Session 7

9:30-11:15 Ito Hall

Chairs: Richard M Locksley ( Department of Medicine / Howard Hughes Medical Institute, University of California San Francisco, CA, USA)

Ken-ichiro Seino ( Institute for Genetic Medicine, Hokkaido University, Hokkaido, Japan)

〈Chairs' Overview〉S7-1 Richard M Locksley

S7-2 ILC2s and Type 2 Immunity Regulate Hair Follicle Stem Cell Proliferation and Skin HomeostasisRoberto R Ricardo-Gonzalez, Steven J Van Dyken, Jinwoo Lee, Richard M Locksley

〈Invited Talk〉S7-3 Defining Group 2 Innate Lymphoid Cell Tissue Niches

Ari B Molofsky

〈Short Talks from Poster〉S7-4 Trafficking and Tissue Tropism of Group 2 Innate Lymphoid Cells

Maxime Petit, Delphine Guy-Grand, Ana Cumano, Rachel Golub

S7-5 Tissue Signals Imprint ILC2 Identity with Anticipatory FunctionSteven Van Dyken, Roberto Ricardo-Gonzalez, Christoph Schneider, Jinwoo Lee, Jesse Nussbaum, Ari Molofsky, Richard Locksley

S7-6 Activation of Memory ILC2s Require Multi-cellular InteractionItziar Martinez-Gonzalez, Maryam Ghaedi, Laura Mathä, Catherine A Steer, Brian Shin, Fumio Takei

S7-7 Protective Memory-like ILC3 Responses Promote Intestinal DefenseNicolas Serafini, Angélique Jarade, Laura Surace, Pedro Goncalves, Philppe Bousso, Gad Frankel, James Di Santo

23

ProgramD

ecember 1

Luncheon Seminar 211:35-12:20 Ito Hall

Chair: Kenji Kabashima ( Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan)

LS-2 Deeper Biological Characterisation Enabled through High-parameter CytometryJohn Scott Wotherspoon ( Cytometry, Research and Training Consultant, BD Life Sciences - Biosciences)

Sponsored by Nippon Becton Dickinson Company, Ltd.


Chairs: Andreas Diefenbach ( Institute of Microbiology, Infectious Diseases and Immunology, Charité - Medical University Berlin, Berlin, Germany)

Shinjiro Hamano ( Department of Parasitology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan)

〈Chairs' Overview〉S8-1 Andreas Diefenbach

〈Invited Talk〉S8-2 Innate Lymphoid Cell Regulation of Intestinal Health

Gregory F Sonnenberg

〈Short Talks from Poster〉S8-3 Investigating the Role of γδ T Cells in Lung Inflammation and Mucus

Metaplasia in Chronic Obstructive Pulmonary DiseaseJessica Geraldine Borger, Maverick Lau, Evelyn Tsantikos, Mhairi J Maxwell, Timothy A Gottschalk, Matthias Ernst, Daniel M Andrews, Gary P Anderson, Margaret L Hibbs

S8-4 Natural IgE Production Requires iNKT Cells and CD1d Expression on B CellsAkihiko Kitoh, Rintaro Shibuya, Kenji Kabashima

S8-5 Group 2 Innate Lymphoid Cells Regulate Susceptibility to Allergic Lung Inflammation via an Innate Amplification CircuitYasutaka Motomura, Shigeo Koyasu, Kazuyo Moro

S8-6 T Cells Regulate the Homeostasis of ILCs through Distinct Mechanisms Depending on the ILC Sub-type and Tissue Micro-environmentMarie Cherrier, Priscillia Bresler, Emmanuel Tejerina, Jean Marie Jacob, Agnes Legrand, Sophie Ezine, Lucie Peduto

24

Program

Decem

ber 1

S8-7 Antigen Presenting ILC3 Regulate T Cell-dependent IgA Responses to Colonic Mucosal-associated BacteriaMatthew Hepworth, Felipe Melo-Gonzalez, Hana Kammoun, Elza Evren, Emma Dutton, Markella Papadopoulou, Barry Bradford, Ceylan Tanes, Kyle Bittinger, Neil Mabbott, Bruce Vallance, Tim Willinger, David Withers


Chairs: Gérard Eberl (Institute Pasteur, Paris, France) Kazuya Iwabuchi ( Department of Immunology, Kitasato University School of Medicine,

Kanagawa, Japan)

〈Chairs' Overview〉S9-1 Gérard Eberl

S9-2 The Central and Peripheric Nervous Systems Control Innate Lymphoid Cells in the Small IntestineMaud Alizee Pascal, Gabriel Lepousez, Gregoire Chevalier, Pierre-Marie Lledo, Gérard Eberl

〈Invited Talk〉S9-3 Neuronal Regulation of Innate Lymphoid Cells

Henrique Veiga-Fernandes

〈Long Talk from Poster〉S9-4 The Enteric Nervous System Regulates Intestinal Inflammation via

Neuromedin UChristoph S N Klose, David Artis

〈Short Talks from Poster〉S9-5 Combinatorial Regulation of Lung ILC2 Responses by an Alarmin and

NeuropeptidesHiroyuki Nagashima, Han-Yu Shih, Fred P Davis, Francoise Meylan, Yuefeng Huang, Chen Yao, Yohei Mikami, Joseph F Urban, Kathleen M Caron, Yasmine Belkaid, Yuka Kanno, John J O’Shea

S9-6 VIPergic Neurons Modulate Activation of ILC3 in the GutJhimmy Talbot, Paul Hann, Henry Nguyen, Maria Pokrovskii, Jason Hall, Dan R Littman

S9-7 Role of Neuroregulators in Adipose Tissue ILC2sFilipa Ribeiro Cardoso, Henrique Veiga-Fernandes

25

Program

Poster Gallery 2

P-1 Characterization of ILC Precursor Potential in Multi-transcription Factor Reporter Mouse ModelsDylan E Cherrier, Wei Xu, Sylvestre Chea, Christian Vosshenrich, Nicolas Serafini, Maxime Petit, Rachel Golub, James P Di Santo

P-2 Tissue Signals Imprint ILC2 Identity with Anticipatory FunctionSteven Van Dyken, Roberto Ricardo-Gonzalez, Christoph Schneider, Jinwoo Lee, Jesse Nussbaum, Ari Molofsky, Richard Locksley

P-3 T Cells Regulate the Homeostasis of ILCs through Distinct Mechanisms Depending on the ILC Sub-type and Tissue Micro-environmentMarie Cherrier, Priscillia Bresler, Emmanuel Tejerina, Jean Marie Jacob, Agnes Legrand, Sophie Ezine, Lucie Peduto

P-4 Sin1 Regulates Group 2 Innate Lymphoid Cell (ILC2) Maintenance and FunctionHongzhi Liu, Yanyun Hao, Jingjing Qi, Liang Li, Xinxing Ouyang, Lei Chen, Lei Shen, Bing Su

P-5 Functional Plasticity of ILC2s to ILC3s Is Determined by the Tissue MicroenvironmentJan-Eric Turner, Martina Becker, Ann-Christin Gnirck, Malte Wunderlich, Constantin Rickassel, Tingting Xiong, Georg Gasteiger

P-6 Innate Lymphoid Cells and Interleukin-22: Functional Analysis in ZebrafishPedro Pablo Hernandez, Paulina Strzelecka, Emmanouil Athanasiadis, Jean-Pierre Levraud, Ana Cvejic

P-7 Combinatorial Regulation of Lung ILC2 Responses by an Alarmin and NeuropeptidesHiroyuki Nagashima, Han-Yu Shih, Fred P Davis, Francoise Meylan, Yuefeng Huang, Chen Yao, Yohei Mikami, Joseph F Urban, Kathleen M Caron, Yasmine Belkaid, Yuka Kanno, John J O’Shea

P-8 Mechanisms for the Regulation of Adipose Tissue Expansion and Remodeling by Group 2 Innate Lymphoid CellsKafi Nequan Ealey, Shigeo Koyasu, Yibo Wu, Kazuyo Moro

P-9 The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid CellsJennifer Kaoru Bando, Susan Gilfillan, Christina Song, Keely G McDonald, Stanley C-C Huang, Rodney D Newberry, Yasuhiro Kobayashi, David SJ Allan, James R Carlyle, Marina Cella, Marco Colonna

26

Program

P-10 Induction of Interleukin-33 Responsive ILC2 and Tregs Reflects an Immune-modulatory Pathway to Counteract Immune-mediated Hepatitis and Hepatic InjuryAaron Ochel, Fabina Heinrich, Gisa Tiegs, Katrin Neumann

P-11 Definition of Natural Killer Cell Heterogeneity in Human and Mouse by High-throughput Single-cell RNA SequencingAdeline M Crinier, Pierre Milpied, Bertrand Escalière, Christelle Piperoglou, Justine Galluso, Anaïs Balsamo, Lionel Spinelli, Inaki Cervera-Marzal, Mikaël Ebbo, Sébastien Jaeger, Emilie Bollon, Sami Hamed, Jean Hardwigsen, Frédéric Vély, Emilie Narni-Mancinelli, Eric Vivier

P-12 Single Cell RNA Sequencing Analysis of Lineage low Lung Cells from RORα Lineage Tracer Mice Reveals Heterogeneity and Potential Immune Regulatory Capacity of Group 2 Innate Lymphoid CellsMaryam Ghaedi, Zi Yi Shen, Lisa Wei, Itziar Martinez-Gonzalez, Marco A Marra, Fumio Takei

P-13 The Enteric Nervous System Regulates Intestinal Inflammation via Neuromedin UChristoph S N Klose, David Artis

P-14 Lung Activated ILC2s Migrate to and Persist in the LiverLaura Mathae, Hanjoo Shim, Catherine Anne Steer, Fabio Rossi, Fumio Takei

P-15 Group 2 Innate Lymphoid Cells Regulate Susceptibility to Allergic Lung Inflammation via an Innate Amplification CircuitYasutaka Motomura, Shigeo Koyasu, Kazuyo Moro

P-16 Trafficking and Tissue Tropism of Group 2 Innate Lymphoid CellsMaxime Petit, Delphine Guy-Grand, Ana Cumano, Rachel Golub

P-17 Inflammasome-associated Cytokines Induce Antigen Presenting Properties in Human ILCsAnna Rao, Mélanie Bruchard, Efthymia Kokkinou, Luca Mazzurana, Heinrich Schlums, Viktoria Konya, Ulrik Lindforss, Hergen Spits, Jenny Mjösberg

P-18 Antigen Presenting ILC3 Regulate T Cell-dependent IgA Responses to Colonic Mucosal-associated BacteriaMatthew Hepworth, Felipe Melo-Gonzalez, Hana Kammoun, Elza Evren, Emma Dutton, Markella Papadopoulou, Barry Bradford, Ceylan Tanes, Kyle Bittinger, Neil Mabbott, Bruce Vallance, Tim Willinger, David Withers

P-19 Quiescent Tissue-resident ILCs Give Rise to a Spectrum of ILC2 and ILC3 Populations in Response to IL-23 StimulationSamantha J Riesenfeld, Piotr Bielecki, Monika Kowalczyk, Carolina Maria Amezcua-Vesely, Abigail Jarret, Ruaidhri Jackson, Will Bailis, Aviv Regev, Richard A Flavell

27

Program

P-20 Transdifferentiated Type 2 Innate Lymphoid Cells Are Important Regulators of Neutrophilia in Cystic FibrosisSuzanne Bal, Korneliusz Golebski, Xavier Ros, Sophie van Tol, Maho Nagasawa, Balthasar Heesters, Hajar Aglmous, Chantal Kradolfer, Cornelis van Drunen, Wytske Fokkens, Hergen Spits

P-21 CD127+ Innate Lymphoid Cells (ILCs) with NK Cell Features Accumulate in Inflammatory Bowel Disease (IBD)Lisette Krabbendam, Chantal Kradolfer, Christianne Buskens, Wilhelmus A Bemelman, Jochem H Bernink, Hergen Spits

P-22 The Human Liver Contains an IL-13-producing ILC3-like Cell That Might Be Involved in Modulation of Hepatic FibrogenesisJan Raabe, Benjamin Krämer, Philipp Lutz, Felix Goeser, Christoph Hoffmeister, Michael To Vinh, Claudia Finnemann, Steffen Manekeller, Vittorio Branchi, Tobias van Bremen, Isis Ludwig-Portugall, Christian P Strassburg, Ulrich Spengler, Jacob Nattermann

P-23 The Human CD117+ Innate Lymphoid Cell Population Contains Committed Precursors of ILC2s and ILC3sMaho Nagasawa, Balthasar A Heesters, Chantal MC Kradolfer, Lisette Krabbendam, Korneliusz Golebski, Hergen Spits, Suzanne M Bal

Poster Gallery 1

P-24 Oxysterol Sensing through the Receptor GPR183 Is Essential for the Migration and Lymphoid Tissue-inducing Function of Innate Lymphoid Cells in the IntestineTim Willinger

P-25 Metabolic Control of Pathologic Versus Protective Functions of Innate Lymphoid Cells at Barrier SitesLaurel Monticelli, Tiffany Huang, Gregory Putzel, David Artis

P-26 Involvement of Innate Lymphoid Cells in the Induction of Diet-induced ObesityTakaharu Sasaki, Kazuyo Moro, Tetsuya Kubota, Naoto Kubota, Hiroshi Ohno, Shigeo Koyasu

P-27 Adipose-derived Stromal Cells Provide a Niche for ILC2-driven Type-2 Immune HomeostasisBatika M J Rana, Jillian L Barlow, Jennifer A Walker, Clare S Hardman, E Suzanne Cohen, Ian C Scott, Matthew A Sleeman, Chiamaka I Chidomere, Sara Cruz Migoni, Jorge Caamano, Helle F Jorgensen, Stefania Carrobio, Antoni Vidal-Puig, Paul J Bryce, Andrew N J McKenzie

28

Program

P-28 ILC2s in the Stomach are Induced by Commensal Bacteria and Protect from Pathogenic InfectionNaoko Satoh, Tamotsu Kato, Yasutaka Motomura, Eisuke Kuroda, Ryo Daitoku Kinoshita, Naoko Atarashi, James Di Santo, Hitomi Mimuro, Kazuyo Moro, Hiroshi Ohno

P-29 Regulation of Type 1 Features in Innate Lymphoid CellsGiuseppe Sciume, Yohei Mikami, Gianluca Scarno, Beatrice Zitti, Han-Yu Shih, Yuka Kanno, John J O'Shea, Angela Santoni

P-30 A Point Mutation in the Ncr1 Signal Peptide Impairs the Development of Innate Lymphoid Cell SubsetsFrancisca Almeida, Sara Tognarelli, Andrew Kueh, Yang Liao, Emilie Narni-Mancinelli, Justine Galluso, Marco Herold, Thierry Walzer, Sophie Ugolini, Wei Shi, Eric Vivier, Evelyn Ullrich, Gabrielle Belz

P-31 IL-33 Signaling Together with Stem Cell Factor Enhances Lung Type 2 Innate Lymphoid Cell ActivationAlan Chuan-Ying Lai, Po-Yu Chi, Christina Li-Ping Thio, Chun-Chou Tsai, Yi-Hsiu Wu, Dale T Umetsu, Ya-Jen Chang

P-32 Aryl-hydrocarbon Receptor-driven Regulation of ILC Responses in Chronic Liver DamageAna Stojanovic, Margareta Correia, Klara Klein, Veronika Sexl, Peter Angel, Michael Platten, Karin Müller-Decker, Adelheid Cerwenka

P-33 GM-CSF-producing Synovial ILCs Exacerbate Th17-mediated Autoimmune ArthritisKeiji Hirota, Motomu Hashimoto, Yoshinaga Ito, Mayumi Matsuura, Hiromu Ito, Masao Tanaka, Hitomi Watanabe, Gen Kondoh, Atsushi Tanaka, Keiko Yasuda, Manfred Kopf, Alexandre J Potocnik, Brigitta Stockinger, Noriko Sakaguchi, Shimon Sakaguchi

P-34 Tracking the Fate of Antigen-specific Versus Cytokine-activated Natural Killer Cells after Cytomegalovirus InfectionTsukasa Nabekura, Lewis L Lanier

P-35 The Roles of ILC2 in Ocular Allergic DiseasesAkira Matsuda, Yosuke Asada, Jobu Sugita, Susumu Nakae

P-36 ILC3s Mediate Early Protection against Mycobaterium TuberculosisAmanda Lee Ardain, Racquel Domingo-Gonzalez, Shibali Das, Samuel W Kazer, Tyler Ulland, Alex K Shalek, Henrik N Kloverpris, Marco Colonna, Shabaana A Khader, Alasdair Leslie

P-37 NKp80 Identifies a Human ILC1-like Cell Population with KIR-independent Cytotoxicity, Impaired in AML PatientsAlejandra Gomez-Cadena, Bérengère Salomé, Romain Loyon, Madeleine Suffiotti, Carsten Riether, Matteo Giovanni Della Porta, David Gfeller, Adrian Ochsenbein, Domenico Mavilio, Antonio Curti, Emanuela Marcenaro, Alexander Steinle, Pedro Romero, Sara Trabanelli, Camilla Jandus

29

Program

P-38 VIPergic Neurons Modulate Activation of ILC3 in the GutJhimmy Talbot, Paul Hann, Henry Nguyen, Maria Pokrovskii, Jason Hall, Dan R Littman

P-39 Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune CircuitJakob von Moltke, Marija S Nadjsombati, John W McGinty, Miranda R Lyons-Cohen, James B Jaffe, Lucian DiPeso, Christoph Schneider, Corey N Miller, Joshua L Pollack, GA Nagana Gowda, Mary F Fontana, David J Erle, Mark S Anderson, Richard M Locksley, Daniel Raftery

P-40 Group 3 Innate Lymphoid Cells Amplify Hippo-Yap1 Signaling Pathways Required for Small Intestinal RepairTom Cupedo, Monica Romera Hernandez, Patricia Aparicio Domingo, Natalie Papazian, Julien J Karrich, Ferry Cornelissen, Remco M Hoogenboezem, Janneke N Samsom

P-41 A Novel Therapeutic Strategy in Ulcerative Colitis through Enforcing IL-22 Production by ILC3Yusuke Yoshimatsu, Yohei Mikami, Kosuke Yoshida, Tomohiro Fukuda, Shinya Sugimoto, Toshiaki Teratani, Shinta Mizuno, Tomohisa Sujino, Makoto Naganuma, Takanori Kanai

P-42 Lipid Droplet Formation Fuels Pathogenic ILC2 Responses in Airway InflammationChristoph Wilhelm, Schekufe Kharabi, Fotios Karagiannis, Vanessa Schmitt, Alexander Kazakov, Surendar Jayagopi

P-43 ILC2s and Type 2 Immunity Regulate Hair Follicle Stem Cell Proliferation and Skin HomeostasisRoberto R Ricardo-Gonzalez, Steven J Van Dyken, Jinwoo Lee, Richard M Locksley

P-44 The Central and Peripheric Nervous Systems Control Innate Lymphoïd Cells in the Small IntestineMaud Alizee Pascal, Gabriel Lepousez, Gregoire Chevalier, Pierre-Marie Lledo, Gérard Eberl

P-45 Hormonal Regulation of Innate Lymphoid CellsCyril Seillet, Sophie Laffont, Kylie Luong, Eve Blanquart, Gilles Laverny, Jean-Philippe Girard, Lucette Pelletier, Jean-Charles Guéry, Gabrielle Belz

P-46 Constitutive CD8 Expression Drives Innate CD8+T Cell Differentiation via NKT2 Subset InductionIchiro Taniuchi, Satoshi Kojo, Michiko Ohno-Oishi, Hisashi Wada, Sebastian Nieke, Sawako Muroi

P-47 Peripheral PDGFRα+gp38+ Mesenchymal Cells Support the Differentiation of Fetal Liver-derived ILC2Satoshi Koga, Katsuto Hozumi, Ken-ichi Hirano, Masaki Yazawa, Tommy Terooatea, Aki Minoda, Takashi Nagasawa, Shigeo Koyasu, Kazuyo Moro

30

Program

P-48 CD56 Marks Human ILC2 Divergence from a Shared NK Cell and ILC3 Developmental PathwayAharon G Freud, Luxi Chen, Youssef Youssef, Cameron Robinson, Gabrielle F Ernst, Mary Y Carson, Steven D Scoville, Xiaoli Zhang, Ansel P Nalin, Emily M Mace, Sujash S Chatterjee, Preethi H Gunaratne, Gregory K Behbehani, Bethany L Mundy-Bosse, Michael A Caligiuri

P-49 NOX2 is Required for the Neonatal LPS Exposure-induced Increase of ILC2s in the LungsYung-Chieh Lin, Tzu-Yi Chan, Cheng-Yuan Hsieh, Shih-Ying Lee, Ki-Chiong Shieh

P-50 Withdrawal

P-51 Emergence of ILC2 Subtype Heterogeneity during Helminth InfectionPatrice Zeis, Mi Lian, Xiying Fan, Cornelia Hilpert, Rebecca Gentek, Marc Bajenoff, Alexander Rudensky, David Voehringer, Georg Gasteiger, Dominic Grün

P-52 iNKT Cell Development in the ThymusHiroshi Watarai

P-53 IL-7 Family of Cytokines Regulate ILC2 Development in Bone Marrow and Response to Airway Viral ImmunityAbdalla Abdussamamd Sheikh, Jennie Jackson, Maryam Ghaedi, Fumio Takei, Ninan Abraham

P-54 Withdrawal

P-55 PLZF Regulates the Function of Group 3 Innate Lymphoid CellsYaru Xu, Shuai Wu, Hongzhi Liu, Lei Shen

P-56 Purinergic Signaling in Gut Innate Lymphoid CellsBlanda Di Luccia, Victor S Cortez, Marco Colonna

P-57 Withdrawal

P-58 RORγt Expressing ILC2s Circulate in Human Peripheral Blood and Have the Capacity to Molecularly Switch into Potent IL-17 Producing CellsYoichiro Ohne, Jingya Wang, Jincheng Wu, Alan Copenhaver, Yashaswi Shrestha, Young Lee, Aaron Berlin, Rajiv Raja, Alison A Humbles

P-59 Heterogeneity in Differentiation Capacity among ILC3-like ILC Precursors in Human TissuesEfthymia Kokkinou, Anna Rao, Jenny Mjösberg

31

Program

P-60 Regulation of ILC1 and NK Cell Plasticity by TGF-β Signaling PathwaysVictor Samuel Cortez, Tyler K Ulland, Luisa Cervantes-Barragan, Jennifer K Bando, Michelle L Robinette, Qianli Wang, Andrew J White, Susan Gilfillan, Marina Cella, Marco Colonna

P-61 Withdrawal

P-62 Investigating ILC Plasticity through Transcriptome Analysis Kentaro Yomogida, Marco Colonna

P-63 Control of Mucosal Defense and Innate Immunity by NeuroregulatorsVania Faria Cardoso, Julie Chésne, Hélder Ribeiro, Bethania Garcia Cassani, Tânia Carvalho, Tiffany Bouchery, Kathleen Shah, Nuno Barbosa Morais, Nicola Harris, Henrique Veiga Fernandes

P-64 Control of Innate Lymphoid Cells by Circadian InputsCristina Godinho-Silva, Rita G Domingues, Miguel Rendas, Bruno Raposo, Hélder Ribeiro, Tânia Carvalho, Henrique Veiga-Fernandes

Poster Event Space

P-65 Role of Neuroregulators in Adipose Tissue ILC2sFilipa Ribeiro Cardoso, Henrique Veiga-Fernandes

P-66 Insulin-like Growth Factor 1 Regulates a Pulmonary Niche Promoting Type 3 Innate Lymphoid Cell Development Necessary for Protection against Pneumonia in the NewbornHitesh Deshmukh, Ian Lang, Jerilyn Gray, Karishma Ponkshe, Aishwarya Varma

P-67 Retinoic Acid Converts Human Group 2 Innate Lymphoid Cells to a Regulatory PhenotypeHideaki Morita, Terufumi Kubo, Susumu Nakae, Hirohisa Saito, Kenji Matsumoto, Mübeccel Akdis, Cezmi A Akdis

P-68 Activation of Memory ILC2s Require Multi-cellular InteractionItziar Martinez-Gonzalez, Maryam Ghaedi, Laura Mathä, Catherine A Steer, Brian Shin, Fumio Takei

P-69 Role of Receptor Activator of NFκB Ligand and Group 2 Innate Lymphoid Cells in Type 2 Inflammation in Chronic Rhinosinusitis with Nasal PolypsNoriko Ogasawara, Julie A Poposki, Aiko I Klingler, Bruce K Tan, Kathryn E Hulse, Whitney W Stevens, Anju T Peters, Robert P Schleimer, Pejman Soroosh, Ken-ichi Takano, Tetsuo Himi, Robert C Kern, Atsushi Kato

P-70 The Function of Hepatic Type 2 Innate Lymphoid Cells Is Regulated by Liver Inflammation-induced Cytokines and Effector CD4+ T CellsKatrin Neumann, Silja Steinmann, Marek Schoedsack, Aaron Ochel, Philippe C Breda, Gisa Tiegs

32

Program

P-71 Posttranscriptional Regulation of Type 2 Cytokine Gene Expression in ILC2Yuki Hikichi, Yasutaka Motomura, Kazuyo Moro

P-72 Mechanisms for Regulation of Type 2 Cytokine Expression by MicroRNA in Group 2 Innate Lymphoid CellsYoshiki Momiuchi, Kazuyo Moro

P-73 Butyrate and Propionate Regulate Proliferation and Activation of Human Group–2 Innate Lymphoid Cells (ILC2s)Keisuke Orimo, Masato Tamari, Hirohisa Saito, Kenji Matsumoto, Hideaki Morita

P-74 IL-9 Producing Type II Innate Lymphoid Cells as New Players in FibrosisStefanie Weber, Simon Rauber, Markus Luber, Matteo Biondi, Thomas Wohlfahrt, Mahmad Ismail Housni, Jutta Jordan, Tobias Bäuerle, Arif Ekici, Stefan Wirtz, Georg Schett, Jörg HW Distler, Andreas Ramming

P-75 Essential Role of c-Rel in IL-33-mediated Activation of Group 2 Innate Lymphoid CellsBarbara Christina Mindt, Claudia Ursula Duerr, Mathieu Mancini, Silvia Marina Vidal, Steve Gerondakis, Philippe Gros, David Langlais, Jorg Hermann Fritz

P-76 Runx Proteins Prevent Group 2 Innate Lymphoid Cells from Exhaustion in Allergic InflammationTakashi Ebihara, Chizuko Miyamoto, Satoshi Kojo, Motoi Yamashita, Kazuyo Moro, Georges Lacaud, Ichiro Taniuchi

P-77 Suppression of Aiolos and Ikaros Expression by Lenalidomide Reduces Human ILC3 to ILC1 Transdifferentiation and Enhances ILC3 FunctionLuca Mazzurana, Marianne Forkel, Anna Rao, Aline Van Acker, Efthymia Kokkinou, Tamaki Ichiya, Sven Almer, Charlotte Höög, Danielle Friberg, Jakob Michaelsson, Jenny Mjösberg

P-78 RORα Directly Regulates Arginase 1 Expression in ILC2Ana C F Ferreira, Jennifer A Walker, Aydan Szeto, Andrew N J McKenzie

P-79 Infants Breastfed with Milk Containing High Long-chain Saturated Fatty Acids (LCSFA) Is Associated with Risk of Atopic Dermatitis Development via an Involvement of ILCsMasamoto Kanno, Weng Sheng Kong, Naohiro Tsuyama, Naoki Shimojo, Hiroko Inoue, Yun Guo

P-80 The NLRP3-dependent Inflammasome Induces ILC3 Activation and Promotes Local Inflammation in the KidneyIsis Ludwig-Portugall, Teresa Maria Frasconi, Christian Kurts

33

Program

P-81 Investigating the Role of γδ T Cells in Lung Inflammation and Mucus Metaplasia in Chronic Obstructive Pulmonary DiseaseJessica Geraldine Borger, Maverick Lau, Evelyn Tsantikos, Mhairi J Maxwell, Timothy A Gottschalk, Matthias Ernst, Daniel M Andrews, Gary P Anderson, Margaret L Hibbs

P-82 Th2 Cell-derived IL-4/IL-13 Promote ILC2 Accumulation in the Lung by ILC2-intrinsic STAT6 SignalingCornelia Symowski, David Voehringer

P-83 The Role of Group 2 Innate Lymphoid Cells in Pulmonary FibrosisNatsuko Otaki, Kazuyo Moro

P-84 An Inhibitory NKT Subset That Suppress Airway HyperreactivityYa-Ting Chuang

P-85 NKT Cell-adipocyte Interaction Have an Important Role in Adipose Tissue InflammationMasashi Satoh, Kazuya Iwabuchi

P-86 The Regulatory Function of NKT Cells in Experimental Autoimmune UveoretinitisTaiki Kato, Masashi Satoh, Kazuya Iwabuchi

P-87 The Protective Role of MAIT Cell in Allergic Contact DermatitisNaoya Imahashi, Masashi Satoh, Kazuya Iwabuchi

P-88 The Effect of Invariant NKT Cell Activation by A-galactosylceramide in the HeartKazuhisa Yoshino, Masashi Satoh, Kazuya Iwabichi

P-89 ILC3 and ILC1 Are Activated in a Model Mouse of Spondyloarthritis with a T Cell Signal DysfunctionYuya Tabuchi, Motomu Hashimoto, Yuri Nakamura, Mirei Shirakashi, Syuji Akizuki, Ran Nakashima, Kosaku Murakami, Hajime Yoshifuji, Masao Tanaka, Koichiro Ohmura, Tsuneyo Mimori

P-90 Enhanced Transdifferentiation to ILC3s Aggravates Inflammatory Arthritis in Mice Lacking Functional Phagocytic NADPH OxidaseTzu-Yi Chan, Chi-Chang Shieh

P-91 Innate Lymphoid Cells in Advanced Stage Chronic Liver Disease and Acute-on Chronic Liver FailureFrank Fasbender, Sarah Schlüter, Ahmed Ghallab, Agata Widera, Jan Hengstler, Carsten Watzl

P-92 Withdrawal

34

Program

P-93 Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth InfectionsChikako Shimokawa, Takashi Kanaya, Masami Hachisuka, Kenji Ishiwata, Hajime Hisaeda, Yosuke Kurashima, Hiroshi Kiyono, Tsuneyasu Kaisho, Hiroshi Ohno

P-94 Protective Memory-like ILC3 Responses Promote Intestinal DefenseNicolas Serafini, Angélique Jarade, Laura Surace, Pedro Goncalves, Philppe Bousso, Gad Frankel, James Di Santo

P-95 HIV Response in Tissue Resident Innate Lymphoid Cells from HIV Infected Children Despite Loss of Circulating ILCs from Early LifeAlveera Singh, Sam Kazer, Julia Roider, Duran Ramsuran, Rabiah Fardoos, Amanda Ardain, Maximiliam Muenchoff, Warren Kuhn, Farina Karim, Thumbi N'dungu, Alex Shalek, Philip Goulder, Alasdair Leslie, Henrik N Kloverpris, Osaretin Asowata

P-96 Targeting Mitochondrial Dysfunction Can Restore Antiviral Activity of NK Cells in HIV InfectionMichael To Vinh, Christina Gotter, Kristiyana Dobrikova, Benjamin Krämer, Jan Raabe, Christoph Hoffmeister, Carolynne Schwarze-Zander, Christian P Strassburg, Jürgen K Rockstroh, Ulrich Spengler, Jacob Nattermann

P-97 The Role of Innate Lymphoid Cells in Cutaneous and Visceral LeishmaniasisCarolin Sasse, Andrea Debus, Christian Bogdan, Ulrike Schleicher

P-98 Respiratory Syncytial Virus Evokes Airway Hyperreactivity and Peripheral Eosinophilia through IL-33-activated Type 2 Innate Lymphoid CellsPo-Yu Chi, Yi-Hsiu Wu, Alan Chuan-Ying Lai, Ya-Jen Chang

P-99 Group 2 Innate Lymphoid Cells Exacerbate Severe Amebic Liver Abscess by IFN-gamma Independent Manner in MiceRisa Nakamura, Sharmina Deloer, Masachika Senba, Mihoko Kikuchi, Shigeo Koyasu, Kazuyo Moro, Shinjiro Hamano

P-100 Crosstalk between ILC3s and T Cells in Protection against Bacterial InfectionAngelique Jarade, Nicolas Serafini, Gad Frankel, James P Di Santo

P-101 The Role of Innate Lymphoid Cells and Aryl Hydrocarbon Receptor during Pulmonary Pseudomonas Aeruginosa InfectionChristina Stehle, Ulrike Uhlig, Pedro Moura-Alves, Stefan HE Kaufmann, Chiara Romagnani

P-102 The Costimulatory Role of ILC3 in Th1 and Th17 T Cell Programmes: Dissecting Critical OX40L Providers in VivoDominika Gajdasik, Claire Willis, Remi Fiancette, Marina Botto, Timothy J Vyse, Gad Frankel, David Ruano-Gallego, David R Withers

35

Program

P-103 Segmented Filamentous Bacteria Exacerbates Lupus Nephritis in Lupus Mice and Promotes an Exacerbation of Both Intestinal Group 3 Innate Lymphoid Cells and Th17 CellsGiancarlo R Valiente, Armin Munir, Takuma Tsuzuki Wada, Jeffrey M Hampton, Perry Blough, Emma E Dalan, William L Willis, Nicholas Young, Lai-Chu Wu, Aharon G Freud, Wael Najib Jarjour

P-104 Withdrawal

P-105 Characteristic of ILC2s from Eosinophilic Rhinosinusitis Patients Using Real-time Single-cell ImagingMasako Matsusaka, Koichi Fukunaga, Satoshi Koga, Kaede Miyata, Takashi Kamatani, Rie Baba, Mai Yamagishi, Takao Mochimaru, Yasutomo Araki, Kenji Kawano, Toru Kikawada, Yoshitaka Shirasaki, Kazuyo Moro, Sotaro Uemura, Tomoko Betsuyaku

P-106 Withdrawal

P-107 Ustekinumab Induces a Shift from ILC1 to ILC3 in Patients with Refractory Crohn’s DiseaseBrecht Creyns, Bram Verstockt, Roselien Vandecasteele, Jonathan Cremer, Marc Ferrante, Séverine Vermeire, Gert Van Assche, Ceuppens Jan, Christine Breynaert

P-108 TGM2+ ILC3 NCR- Are Enhanced in Children with Celiac DiseaseSara Trabanelli, Giuseppe Ercolano, Tania Wyss Lozano Hoyos, Alex Moretti, Michela Gaiazzi, Alessandra Tozzo, Silvia Salvatore, Camilla Jandus

P-109 Innate Lymphoid Cells Subsets in Peripheral Blood of Patients with Asthma Treated with MepolizumabHitoshi Sasano, Norihiro Harada, Sonoko Harada, Yuki Tanabe, Yuuki Sandhu, Tomohito Takeshige, Kei Matsuno, Ayako Ishimori, Fumihiko Makino, Jun Ito, Asako Chiba, Sachiko Miyake, Kazuhisa Takahashi

P-110 Type 3 Innate Lymphoid Cells Secreting IL-17A Orchestrate HDM-induced Atopic Dermatitis-like Inflammation Dong Hun Lee, Minho Kim, Seon-Pil Jin, Doo Hyun Chung, Kyu Han Kim, Hye Young Kim

P-111 Group 3 Innate Lymphoid Cells Are Associated with Smoking in Asthmatic PatientsJongho Ham, Jihyun Kim, Hye Young Kim

P-112 Immunosuppressive Mediators Impair Pro-inflammatory ILC Functions in Human Malignant MelanomaCamilla Jandus, Bérengère Salomé, Beatris Mastelic-Gavillet, Giuseppe Ercolano, Daniel E Speiser, Pedro Romero, Sara Trabanelli

36

Program

P-113 ILC3-like NK Cells Promote Tumor Growth in Head and Neck Squamous Cell CarcinomaDavid C Mundy, Uriel Y Moreno-Nieves, Serena C Chang, Saumyaa Mittal, June Ho Shin, John B Sunwoo

P-114 Unravelling Innate Lymphoid Cell Regulation in Lymphoma PatientsStefania Roma, Patrizia Mancuso, Chiara Camisaschi, Sara Trabanelli, Camilla Jandus, Francesco Bertolini

P-115 Novel Protocol for the Isolation and Ex Vivo Expansion of Group 2 Innate Lymphoid CellsClaudia Duerr, Barbara C Mindt, Connor McCarthy, Regina Cencic, Tho-Alfakar Al-Aubodah, Jerry Pelletier, Jörg H Fritz

P-116 Nkp80 Expression on Human Liver CD49a+ NK Cells Define Two Subsets with Different FunctionsBenjamin Kraemer, Philipp Lutz, Felix Goeser, Claudia Finnemann, Vittorio Branchi, Jan Raabe, Hans Dieter Nischalke, Michael ToVinh, Christoph Hoffmeister, Joerg Timm, Joerg Pollok, Jeanette Bierwolf, Christian P Strassburg, Ulrich Spengler, Jacob Nattermann

P-117 Graft-versus-host Disease Leads to Systemic Elimination of Innate Lymphoid Cells and Abolishes Their DevelopmentPaola Vinci, Elena Garcia-Martinez, Margaret H. O'Connor, Anastasiya Egorova, Anna M. Mertelsmann, Eileen Nicoletti, Clair D. Geary, Sean M. Devlin, Chen Liu, Joseph C. Sun, Marcel RM van den Brink, Robert R. Jenq, Alan M. Hanash

P-118 The Role of Group 2 Innate Lymphoid Cells (ILC2s) in the Pathogenesis of Allergic RhinitisIchiro Tojima, Koji Matsumoto, Hirotaka Kikuoka, Shiori Hara, Sayuri Yamamoto, Shino Shimizu, Hideaki Kouzaki, Takeshi Shimizu

P-119 Lung Resident ILC2s Are Trained by Endogenously Released IL-33 in the Neonatal Period Catherine A Steer, Hanjoo Shim, Laura Mathae, Fabio Rossi, Fumio Takei

P-120 Peripheral Blood Type 2 Innate Lymphoid Cells of Asthmatic Patients Display an Activated Effector CharacteristicsKorneliusz Golebski, Joannah Fergusson, Hergen Spits, Suzanne Bal

P-121 Pulmonary ILC2s Express Toll-like Receptor 2 (TLR2) and Its Can Modify Asthmatic Characteristics through TLR2Takashi Ishii, Tomoya Narita, Yusuke Murakami, Yuichi Nikura, Takahide Nagase, Naomi Yamashita

P-122 The Potential Role of Innate Lymphoid Cells in Severe Asthmatic PatientsAnne-Charlotte Jonckheere, Sven F Seys, Tatjana Decaesteker, Jonathan Cremer, Kornel Gobleski, Xavier Romero-Ros, Christine Breynaert, Jan Ceuppens, Lieven Dupont, Dominique MA Bullens

37

Program

P-123 A Gammaherpesvirus Affects Group 2 Innate Lymphoid Cells in the Context of HDM-Induced AsthmaPauline Loos, Céline Maquet, Justine Javaux, Bénédicte Machiels, Laurent Gillet

P-124 Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type2-innate Lymphoid Cell ResponseRyuichi Nagashima, Hitomi Kosai, Keiko Izumiyama, Nobuyuki Tanaka

P-125 Understanding ILC2 Migration and Interactions during Allergic Inflammation Using Lung Intravital MicroscopyEmma Lefrancais, Jean-Philippe Girard

P-126 The Microbial Metabolite Butyrate Regulates Type 2 Innate Lymphoid Cell-dependent Airway HyperreactivityChristina Li-Ping Thio, Po-Yu Chi, Alan Chuan-Ying Lai, Ya-Jen Chang

P-127 Serum Amyloid A Promote IL-17A Production by Group 3 Innate Lymphoid Cells via Neutrophilic Inflammation in Chronic Obstructive Pulmonary DiseaseJihyun Kim, Hye Young Kim

P-128 The Immunological Aspect of hUC-MSC on Murine Respiratory System Jaewoo Shin, Seungwon Ryu, HyeRyun Kang, HyeYoung Kim

P-129 Group 2 Innate Lymphoid Cell Deficiency Does Not Alter the Severity of Renal Ischemia-reperfusion InjuryGuy John-Malcolm Cameron, Svenja Loering, Aniruddh Vijay Deshpande, Andrew Neil James McKenzie, Philip Michael Hansbro, Malcolm Ronald Starkey

P-130 Type I Interferon Inhibition of Cutaneous Group 2 Innate Lymphocytes: A Key Relationship in Patients with Systemic Lupus ErythematosusGiancarlo R Valiente, Perry Blough, Takuma Tsuzuki Wada, Armin Munir, Kai Quin, Emma E Dalan, Rachel Brown, William L Willis, Lai-Chu Wu, Aharon G Freud, Wael Najib Jarjour

P-131 Basophil-derived IL-4 Aggravates ILC2-dependent Atopic Dermatitis-like Inflammation in Mice Overexpressing IL-33 in the SkinYasutomo Imai, Koubun Yasuda, Minori Kusakabe, Makoto Nagai, Kenji Nakanishi, Kiyofumi Yamanishi

P-132 Role of Group 2 Innate Lymphoid Cells in AngiogenesisHiroe Tetsu, Kazuyo Moro

P-133 ILC Migration between Barriers Sites and Draining Lymphoid TissueEmma Elizabeth Dutton, Claire Willis, Ana Camelo, Matthew Sleeman, Gianluca Carlesso, Ronald Herbst, Alison Humbles, David Withers

38

Program

P-134 Group 3 Innate Lymphoid Cells Regulate the Intestinal Mucosal Adaptive Immune Responses through ID2-dependent PathwayYiping Li, Wenyan Wang, Xiaohuan Guo

P-135 Natural IgE Production Requires iNKT Cells and CD1d Expression on B CellsAkihiko Kitoh, Rintaro Shibuya, Kenji Kabashima

P-136 Regulation of Arthritis by Type 2 Innate Lymphoid CellsYasunori Omata, Stefan Wirtz, Georg Schett, Mario M Zaiss

P-137 Suppression of Critical Transcriptional Programs for ILC2 Differentiation by E Protein Transcription FactorsXiao-Hong Sun, Liangyue Qian, Sandra Bajana, Constantin Georgescu, Vincent Peng, Hong-Cheng Wang, Indra Adriano, Jose Alberola-Ila, Marco Colonna, Jonathan D Wren

P-138 Neuronal Regulation of Type 2 Innate Lymphoid Cells via Neuromedin UJulie Chesné, Vânia Cardoso, Hélder Ribeiro, Bethania García-Cassani, Tânia Carvalho, Tiffany Bouchery, Kathleen Shah, Nuno L Barbosa-Morais, Nicola Harris, Henrique Veiga-Fernandes

P-139 In Vivo Depletion of T-bet in Intestinal Innate Lymphoid CellsJan-Hendrik Schroeder, Jonathan W Lo, Helena Helmby, Graham M Lord

P-140 Group 3 ILCs: Development and Role in AutoimmunityArthi Shanmugavadivu, Tommy Regen, Ari Waisman

P-141 RANKL+mesenchymal Cell is the Genuine Lymphoid Tissue Organizer Cell in the Developing Lymph-nodeShinichiro Sawa, Eriko Sumiya, Kenta Nakano, Tadashi Okamura

november 29 (thu.)

Documents