nucleic acids - dna is a polynucleotide, usually double stranded, made up of nucleotides with bases...
TRANSCRIPT
![Page 1: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/1.jpg)
NUCLEIC ACIDS
- DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G.- RNA is a polynucleotide, usually single stranded made up of nucleotides containing the bases A,U,C and G.
Objective:describe the structure of RNA and DNA and explain the importance of base pairing and hydrogen bonding
![Page 2: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/2.jpg)
CENTRAL DOGMA OF BIOLOGY
![Page 3: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/3.jpg)
HOMEWORK:
Devise and complete a table of key roles for each specified ion – information coming from bibliographic and web-based research
in living organisms: calcium, sodium, potassium, magnesium, chloride, nitrate, phosphate
![Page 4: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/4.jpg)
NUCLEIC ACIDS
They come in two forms:
1) DNA (deoxyribonucleic acid)2) RNA (Ribonucleic acid)
DNA in eukaryotic cells are found in the nucleus, acting as a information store.
![Page 5: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/5.jpg)
CONTINUED…
Nucleic acids are composed of monomers called a nucleotide.
A nucleotide is composed of 3 subunits:
One phosphate group;One sugar molecule ;One organic nitrogenous base.
These subunits are joined by covalent bonds to form a nucleotide molecule.
![Page 6: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/6.jpg)
![Page 7: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/7.jpg)
BASE TYPES
![Page 8: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/8.jpg)
![Page 9: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/9.jpg)
FEATURES OF NUCLEOTIDES
DNA(double helix) RNA(single)
Same phosphate group Same phosphate group
5-carbon sugar normally deoxyribose
5-carbon sugar normally ribose
Base pairs Guanine, Cytosine, Adenine and Thymine
Base pairs, Guanine, Adenine, Cytosine and Uracil.
![Page 10: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/10.jpg)
JOINING NUCLEOTIDES
A condensation reaction between the phosphate group of one nucleotide and the sugar of another join the two together.
This forms chains called the “Backbone.” Organic bases will project from this, and it is this sequence of bases that forms coded information of nucleic acid.
![Page 11: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/11.jpg)
![Page 12: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/12.jpg)
HOW NUCLEOTIDES JOIN TOGETHER
![Page 13: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/13.jpg)
DNA STRUCTURE
![Page 14: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/14.jpg)
![Page 15: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/15.jpg)
BASE PAIR- ACRONYM
Gangsters – Can
Ask - Time
A-T 2 H bonds
G-C 3 H-bonds
![Page 16: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/16.jpg)
DRAW AND LABEL THE DIAGRAM EVERY COMPONENT AND BOND
![Page 17: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/17.jpg)
DRAW AND LABEL
![Page 18: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/18.jpg)
ribosomal RNA (rRNA)
Makes up the bulk of the ribosome.
Large folded molecule.
![Page 19: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/19.jpg)
messenger RNA (mRNA)
Carries the genetic message from DNA in the nucleus to the ribosomes where proteins are synthesised (made) accordingly.
Long molecule, not folded.
Variable in length and base sequence.
Readily broken down and remade.
![Page 20: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/20.jpg)
Collects amino acids and takes them to the ribosomes for assembly into proteins.
Small molecule.
Winds back on itself to form a “clover-leaf” shape.
One end carries an amino acid.
One loop has a special triplet of bases (ANTICODON) whichdetermines the amino acid carried.
transfer RNA (tRNA)
AMINO ACID
ANTICODON
![Page 21: NUCLEIC ACIDS - DNA is a polynucleotide, usually double stranded, made up of nucleotides with bases A,T,C and G. - RNA is a polynucleotide, usually single](https://reader031.vdocument.in/reader031/viewer/2022012916/56649d0a5503460f949dc70e/html5/thumbnails/21.jpg)
RIBONUCLEIC ACID (RNA)
Single stranded polynucleotide.
Sugar is always ribose.
Organic bases are always A, G, C, and U, NEVER T.
3 types :- ribosomal RNA (rRNA)messenger RNA (mRNA)transfer RNA (tRNA)
Back