nucleotide synthesis (de-novo and salvage pathways of purine & pyrimidine biosynthesis ppt by...
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NUCLEOTIDE BIOSYNTHESISBio-synthesis of Purines & Pyrimidines
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“The formation of DNA's structure by Watson and Crick may turn out to be the
greatest developments in the field of molecular genetics in recent years”
Linus Pauling, 1953
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Learning objectives:How nucleotides are synthesized in the cells?
Understand the Two Pathways of nucleotide biosynthesis
(1). De-novo synthesis and (2). Salvage Pathways
De-novo synthesis of purines
Synthesis of IMP (precursor of adenine and guanine)
Synthesis of Adenine and Guanine from IMP
De-novo synthesis of pyrimidines
Synthesis of Uracil
Synthesis of Cytosine
Synthesis of deoxy nucleotides
Synthesis of Thymine
Salvage pathways of Purines and Pyrimidines
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NUCLEOTIDE BIOSYNTHESIS
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o-salvage-purine-pyrimidine-nucleotides-cells
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