oesophageal atresia anne aspin 2010. types of oesophageal atresia and fistula 86%7% 4%
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OESOPHAGEAL OESOPHAGEAL ATRESIAATRESIA
OESOPHAGEAL OESOPHAGEAL ATRESIAATRESIAAnne AspinAnne Aspin
20102010
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Types of oesophageal atresia and fistula
86% 7%4%
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Types continued
1%<1
<1
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History• First case recorded Durston (1670)• Gibson (1697) first recorded with
fistula• Ladd (1939) first staged repair• Height (1941) first successful
primary repair.
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• Survival rate of around 90%• Incidence 1: 4500• Antenatal diagnosis –
polyhydramnios and absent stomach 56% predictive of OA.
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After birth• Large NG tube• CXR, AXR• Replogle tube, 10 min suction to
pharynx
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Associated anomalies• 50% associated anomalies• Cardiac 29%
• Vertebral, Anorectal, Cardiac, Tracheo, Oesophageal, Renal, Limb
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• CHARGE, Coloboma, Heart defects, Atresia choanal, retarded growth and development, Genital Hypoplasia, Ear
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Table 1• Cardiovascular 29%• Gastro intestinal (anorectal 14%)
27%• Genito urinary 13%• Vertebral and skeletal 10%• Respiratory 6%• Genetic 4%
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Table 2• Risk classification for OA• Group BW Major cardiac survival defect 1 >1500 No 96% 2 <1500 or Yes 60% 3 <1500 and Yes 18%
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Primary repair• Paralyse and ventilate 5 days post
op• Long gap – gastrostomy and
assessment of gap, may leave 6 – 12 weeks before primary closure.
• Gap of more than 6-8 vertebrae, oesophageal replacement
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Post operation- early complications
• Anastomotic leak , 27%, 24 – 72hrs
• Anastomotic stricture
• Recurrent tracheo oesophageal fistula
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Late complications• Tracheomalacia• Gastro oesophageal reflux• Respiratory problems• Motility disorders• Growth
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Research• Family study – broad spectrum• Relatives of TOF have these
anomalies (genetic factor)• Range of medical problems ie
dysmotility, reflux –family have these. (Genetic story to investigate)
• Vitamin A, Adriamycin (cancer drug)