onsite aerosol measurements for various engineered
TRANSCRIPT
Journal of Physics Conference Series
OPEN ACCESS
Onsite aerosol measurements for variousengineered nanomaterials at industrialmanufacturing plantsTo cite this article I Ogura et al 2011 J Phys Conf Ser 304 012004
View the article online for updates and enhancements
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This content was downloaded from IP address 2231613894 on 26112021 at 2029
Onsite aerosol measurements for various engineered
nanomaterials at industrial manufacturing plants
I Ogura H Sakurai and M Gamo
National Institute of Advanced Industrial Science and Technology (AIST) 16-1
Onogawa Tsukuba Ibaraki 305-8569 Japan
E-mail i-oguraaistgojp
Abstract Evaluation of the health impact of and control over exposure to airborne engineered
nanomaterials (ENMs) requires information inter alia the magnitude of environmental release
during various industrial processes as well as the size distribution and morphology of the
airborne ENM particles In this study we performed onsite aerosol measurements for various
ENMs at industrial manufacturing plants The industrial processes investigated were the
collection of SiC from synthesis reactors synthesis and bagging of LiFePO4 and bagging of
ZnO Real-time aerosol monitoring using condensation particle counters optical particle
counters and an electrical low-pressure impactor revealed frequent increases in the number
concentrations of submicron- and micron-sized aerosol particles but few increases in the
number concentrations of nanoparticles In the SEM observations a large number of
submicron- and micron-sized agglomerated ENM particles were observed
1 Introduction
Although engineered nanomaterials (ENMs) have many potential benefits for society there is growing
concern about their potential impact on health [1] A significant exposure route is inhalation of
airborne ENMs during manufacture and handling Information on airborne ENMs such as the
magnitude of release and the industrial processes involved as well as particle size distribution and
morphology is required in order to evaluate and control ENM exposure [2]
In this study we performed onsite aerosol measurements for various ENMs at industrial
manufacturing plants The processes investigated were the collection of silicon carbide (SiC) from
synthesis reactors synthesis and bagging of lithium iron phosphate (LiFePO4) and bagging of zinc
oxide (ZnO) The investigations were conducted in collaboration with the National Institute of
Occupational Safety and Health Japan (JNIOSH) However this paper presents only the results
obtained by the National Institute of Advanced Industrial Science and Technology (AIST)
2 Methods
21 Real-time aerosol monitoring
The number concentrations and size distributions of aerosol particles were measured using real-time
aerosol monitoring instruments viz condensation particle counters (CPCs model 3007 TSI Inc
USA 10 to gt1000 nm) optical particle counters (OPCs Handheld 3016 Lighthouse Worldwide
Solutions Inc USA optical diameters of gt300 gt500 gt1000 gt3000 gt5000 and gt10000 nm) and an
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
Published under licence by IOP Publishing Ltd 1
electrical low-pressure impactor (ELPI Dekati Ltd Finland aerodynamic diameters of 7ndash10000 nm
12 channels) A stainless pipe and conductive silicone tubing were used to transmit the particles from
the sampling point around the work area to the measuring instruments The sampling flow rates of the
CPC OPC and ELPI were 07 28 and 10 Lmin respectively and the average time was 10 s per
sample
22 Filter sampling and electron microscope observation
The aerosol particles were collected on a Nuclepore membrane filter (diameter of 25 mm pore size of
0080 microm Nomura Micro Science Co Ltd Japan) with a stainless steel filter holder (available
filtration area of 380 mm2 KS-25F Advantec Toyo Kaisha Ltd Japan) for electron microscopy
analysis The sampling flow rate was set at approximately 1ndash2 Lmin A stainless pipe and conductive
silicone tubing were used to transmit the particles from the sampling point around the work area to the
sampling filter
The aerosol particles collected on the Nuclepore filters were observed using a field-emission
scanning electron microscope (SEM S-4300 Hitachi High-Technologies Corporation Japan) under
an accelerating voltage of 1 kV Before the SEM observation the samples mounted on SEM grids
were coated with platinumndashpalladium (approximately 1 nm) to avoid image charging
23 Processes investigated
We performed onsite aerosol measurement for ENMs at industrial plants manufacturing ENMs during
the following processes
231 Collection of SiC from synthesis reactors During the collection of SiC from two reactors after
synthesis by thermal plasma chemical vapor deposition the aerosol particles at a site near to the work
area (approximately 50ndash100 cm) and at a site far from the work area (approximately 5 m) were
measured simultaneously Because the room had a ventilation system with a high efficiency particulate
air (HEPA) filter the aerosol particle concentrations in the room during nonworking periods were
generally low The representative characteristics of SiC provided by the manufacturer are as follows
the average primary particle diameter is 30 nm and the specific surface area is 50 m2g
232 Synthesis and bagging of LiFePO4 LiFePO4 which is used as the cathode materials in lithium-
ion batteries is synthesized by sintering a precursor material the nature of this material is
confidential Aerosol particles were measured at a distance of approximately 60 cm from the work
area where the synthesized LiFePO4 was being bagged (1100ndash1320) and approximately 100 cm from
the work area where the precursor material was being filled into containers and weighed (1320ndash
1520) In addition the aerosol particles in the air entering through the outside air intake were
simultaneously measured Both LiFePO4 and precursor material mainly consist of the primary particles
with a diameter of approximately a hundred to a few hundred nanometers
233 Bagging of ZnO When the synthesized ZnO was being bagged aerosol particles at a distance
of approximately 50ndash100 cm from the work area and outdoors were measured simultaneously
Although the hoppers of ZnO were automatically emptied into drums which were lined with plastic
bags the processes of disconnecting the bags containing the synthesized ZnO from the hopper outlets
sealing the bags and connecting the empty bags in the drums to the hopper outlets were performed
manually The bagging began at 1000 and ZnO was filled into ten drums during a period of three
hours ie till 1300 The primary particle diameter was a few tens of nanometers as observed through
the SEM (see section 32)
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
2
3 Results
31 Particle number concentrations and size distributions of released airborne ENMs
311 Collection of SiC from synthesis reactors Figure 1 shows the changes in the particle number
concentrations measured by the CPCs and OPCs When collecting SiC from the two synthesis reactors
(first 1054ndash1105 and second 1110ndash1117) the number concentrations of micron-sized particles
increased whereas those of nano- and submicron-sized particles did not
Figure 2 shows the particle size distributions during the SiC collection (highest 10-s-average
concentration at 1110) and before it (ie the average concentration in the period 1042ndash1054) at the
site near to the work area measured by the ELPI and OPC Figure 2 indicates that the number
concentrations of particles with a diameter greater than a few hundred nanometers were higher during
the collection process than before
0
500
1000
1500
2000
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
0
5
10
15
20
0
5
10
15
20
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
1
2
3
4
5
6
0
1
2
3
4
5
6
Collection Collection
Site near to work area
Site far from work area
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Site near to work area
Site far from work area
Site near to work area
Site far from work area
Figure 1 Changes in the particle number concentrations at a site near to and at a site far from
the work area where SiC was collected from the synthesis reactors
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
3
0001
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
ELPI
OPC
Before SiC collection
During SiC collection
Before SiC collection
During SiC collection
Figure 2 Particle size distributions during and before the collection of SiC Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
312 Synthesis and bagging of LiFePO4 Figure 3 shows the changes in the particle number
concentrations measured by the CPCs and OPCs near the work areas where the synthesized LiFePO4
was bagged (1100ndash1320) and where the precursor material was filled into containers and weighed
(1320ndash1520) and outdoors (1100ndash1520) The number concentrations of submicron- and micron-
sized particles increased when a bag containing LiFePO4 was being disconnected from the hopper
outlet and sealed (1135 and 1250) and when filling and weighing the precursor material (1140ndash
1152 1400ndash1424)
Figure 4 shows the particle size distributions during the bagging of LiFePO4 (highest 10-s-average
concentration at 1135) and before it (ie the average concentration in the period 1120ndash1134) near
the work area measured by ELPI and OPC Figure 5 shows the particle size distributions during the
filling and weighing of the precursor material (ie the average concentration in the period 1400ndash
1424) and before it (ie the average concentration in the period 1350ndash1400) near the work area
measured by the ELPI and OPC Figures 4 and 5 indicate that the number concentrations of particles
with a diameter greater than several hundred nanometers increased when LiFePO4 was being bagged
and when filling and weighing the precursor material
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
4
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
100
50
150
0
100
50
150 Bagging of
LiFePO4
Filling and weighing
of precursor material
0
100
50
150
200
0
10000
20000
30000
0
10000
20000
30000
1100 1200 1300 1400 15001100 1200 1300 1400 1500
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Filling and weighing
of precursor material
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 3 Changes in the particle number concentrations near the work areas where
synthesized LiFePO4 was bagged (1100ndash1320) and where the precursor material was
filled into containers and weighed (1320ndash1520) and outdoors (1100ndash1520)
dN
dlo
gD
p[p
arti
cles
cm
3] ELPI
OPC
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
Before bagging of LiFePO4
During bagging of LiFePO4
Before bagging of LiFePO4
During bagging of LiFePO4
Figure 4 Particle size distributions during and before the bagging of LiFePO4 Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
5
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
ELPI
OPC
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
Figure 5 Particle size distributions during and before the filling and weighing of the precursor
material Particle sizes are expressed in terms of aerodynamic diameter for ELPI and optical
diameter for OPC
313 Bagging of ZnO Figure 6 shows the changes in the particle number concentrations measured by
the CPCs and OPCs near the work area and outdoors during the bagging of ZnO (1000ndash1300) The
number concentrations of micron-sized particles were slightly higher near the work area than outdoors
Figure 7 shows the particle size distributions during the bagging of ZnO (highest 10-s-average
concentration at 1115) and before it (ie the average concentration in the period 955ndash1000) near the
work area measured by the ELPI and OPC The number concentrations of micron-sized particles
during the bagging of ZnO were slightly higher than those before
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
6
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
Onsite aerosol measurements for various engineered
nanomaterials at industrial manufacturing plants
I Ogura H Sakurai and M Gamo
National Institute of Advanced Industrial Science and Technology (AIST) 16-1
Onogawa Tsukuba Ibaraki 305-8569 Japan
E-mail i-oguraaistgojp
Abstract Evaluation of the health impact of and control over exposure to airborne engineered
nanomaterials (ENMs) requires information inter alia the magnitude of environmental release
during various industrial processes as well as the size distribution and morphology of the
airborne ENM particles In this study we performed onsite aerosol measurements for various
ENMs at industrial manufacturing plants The industrial processes investigated were the
collection of SiC from synthesis reactors synthesis and bagging of LiFePO4 and bagging of
ZnO Real-time aerosol monitoring using condensation particle counters optical particle
counters and an electrical low-pressure impactor revealed frequent increases in the number
concentrations of submicron- and micron-sized aerosol particles but few increases in the
number concentrations of nanoparticles In the SEM observations a large number of
submicron- and micron-sized agglomerated ENM particles were observed
1 Introduction
Although engineered nanomaterials (ENMs) have many potential benefits for society there is growing
concern about their potential impact on health [1] A significant exposure route is inhalation of
airborne ENMs during manufacture and handling Information on airborne ENMs such as the
magnitude of release and the industrial processes involved as well as particle size distribution and
morphology is required in order to evaluate and control ENM exposure [2]
In this study we performed onsite aerosol measurements for various ENMs at industrial
manufacturing plants The processes investigated were the collection of silicon carbide (SiC) from
synthesis reactors synthesis and bagging of lithium iron phosphate (LiFePO4) and bagging of zinc
oxide (ZnO) The investigations were conducted in collaboration with the National Institute of
Occupational Safety and Health Japan (JNIOSH) However this paper presents only the results
obtained by the National Institute of Advanced Industrial Science and Technology (AIST)
2 Methods
21 Real-time aerosol monitoring
The number concentrations and size distributions of aerosol particles were measured using real-time
aerosol monitoring instruments viz condensation particle counters (CPCs model 3007 TSI Inc
USA 10 to gt1000 nm) optical particle counters (OPCs Handheld 3016 Lighthouse Worldwide
Solutions Inc USA optical diameters of gt300 gt500 gt1000 gt3000 gt5000 and gt10000 nm) and an
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
Published under licence by IOP Publishing Ltd 1
electrical low-pressure impactor (ELPI Dekati Ltd Finland aerodynamic diameters of 7ndash10000 nm
12 channels) A stainless pipe and conductive silicone tubing were used to transmit the particles from
the sampling point around the work area to the measuring instruments The sampling flow rates of the
CPC OPC and ELPI were 07 28 and 10 Lmin respectively and the average time was 10 s per
sample
22 Filter sampling and electron microscope observation
The aerosol particles were collected on a Nuclepore membrane filter (diameter of 25 mm pore size of
0080 microm Nomura Micro Science Co Ltd Japan) with a stainless steel filter holder (available
filtration area of 380 mm2 KS-25F Advantec Toyo Kaisha Ltd Japan) for electron microscopy
analysis The sampling flow rate was set at approximately 1ndash2 Lmin A stainless pipe and conductive
silicone tubing were used to transmit the particles from the sampling point around the work area to the
sampling filter
The aerosol particles collected on the Nuclepore filters were observed using a field-emission
scanning electron microscope (SEM S-4300 Hitachi High-Technologies Corporation Japan) under
an accelerating voltage of 1 kV Before the SEM observation the samples mounted on SEM grids
were coated with platinumndashpalladium (approximately 1 nm) to avoid image charging
23 Processes investigated
We performed onsite aerosol measurement for ENMs at industrial plants manufacturing ENMs during
the following processes
231 Collection of SiC from synthesis reactors During the collection of SiC from two reactors after
synthesis by thermal plasma chemical vapor deposition the aerosol particles at a site near to the work
area (approximately 50ndash100 cm) and at a site far from the work area (approximately 5 m) were
measured simultaneously Because the room had a ventilation system with a high efficiency particulate
air (HEPA) filter the aerosol particle concentrations in the room during nonworking periods were
generally low The representative characteristics of SiC provided by the manufacturer are as follows
the average primary particle diameter is 30 nm and the specific surface area is 50 m2g
232 Synthesis and bagging of LiFePO4 LiFePO4 which is used as the cathode materials in lithium-
ion batteries is synthesized by sintering a precursor material the nature of this material is
confidential Aerosol particles were measured at a distance of approximately 60 cm from the work
area where the synthesized LiFePO4 was being bagged (1100ndash1320) and approximately 100 cm from
the work area where the precursor material was being filled into containers and weighed (1320ndash
1520) In addition the aerosol particles in the air entering through the outside air intake were
simultaneously measured Both LiFePO4 and precursor material mainly consist of the primary particles
with a diameter of approximately a hundred to a few hundred nanometers
233 Bagging of ZnO When the synthesized ZnO was being bagged aerosol particles at a distance
of approximately 50ndash100 cm from the work area and outdoors were measured simultaneously
Although the hoppers of ZnO were automatically emptied into drums which were lined with plastic
bags the processes of disconnecting the bags containing the synthesized ZnO from the hopper outlets
sealing the bags and connecting the empty bags in the drums to the hopper outlets were performed
manually The bagging began at 1000 and ZnO was filled into ten drums during a period of three
hours ie till 1300 The primary particle diameter was a few tens of nanometers as observed through
the SEM (see section 32)
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
2
3 Results
31 Particle number concentrations and size distributions of released airborne ENMs
311 Collection of SiC from synthesis reactors Figure 1 shows the changes in the particle number
concentrations measured by the CPCs and OPCs When collecting SiC from the two synthesis reactors
(first 1054ndash1105 and second 1110ndash1117) the number concentrations of micron-sized particles
increased whereas those of nano- and submicron-sized particles did not
Figure 2 shows the particle size distributions during the SiC collection (highest 10-s-average
concentration at 1110) and before it (ie the average concentration in the period 1042ndash1054) at the
site near to the work area measured by the ELPI and OPC Figure 2 indicates that the number
concentrations of particles with a diameter greater than a few hundred nanometers were higher during
the collection process than before
0
500
1000
1500
2000
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
0
5
10
15
20
0
5
10
15
20
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
1
2
3
4
5
6
0
1
2
3
4
5
6
Collection Collection
Site near to work area
Site far from work area
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Site near to work area
Site far from work area
Site near to work area
Site far from work area
Figure 1 Changes in the particle number concentrations at a site near to and at a site far from
the work area where SiC was collected from the synthesis reactors
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
3
0001
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
ELPI
OPC
Before SiC collection
During SiC collection
Before SiC collection
During SiC collection
Figure 2 Particle size distributions during and before the collection of SiC Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
312 Synthesis and bagging of LiFePO4 Figure 3 shows the changes in the particle number
concentrations measured by the CPCs and OPCs near the work areas where the synthesized LiFePO4
was bagged (1100ndash1320) and where the precursor material was filled into containers and weighed
(1320ndash1520) and outdoors (1100ndash1520) The number concentrations of submicron- and micron-
sized particles increased when a bag containing LiFePO4 was being disconnected from the hopper
outlet and sealed (1135 and 1250) and when filling and weighing the precursor material (1140ndash
1152 1400ndash1424)
Figure 4 shows the particle size distributions during the bagging of LiFePO4 (highest 10-s-average
concentration at 1135) and before it (ie the average concentration in the period 1120ndash1134) near
the work area measured by ELPI and OPC Figure 5 shows the particle size distributions during the
filling and weighing of the precursor material (ie the average concentration in the period 1400ndash
1424) and before it (ie the average concentration in the period 1350ndash1400) near the work area
measured by the ELPI and OPC Figures 4 and 5 indicate that the number concentrations of particles
with a diameter greater than several hundred nanometers increased when LiFePO4 was being bagged
and when filling and weighing the precursor material
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
4
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
100
50
150
0
100
50
150 Bagging of
LiFePO4
Filling and weighing
of precursor material
0
100
50
150
200
0
10000
20000
30000
0
10000
20000
30000
1100 1200 1300 1400 15001100 1200 1300 1400 1500
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Filling and weighing
of precursor material
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 3 Changes in the particle number concentrations near the work areas where
synthesized LiFePO4 was bagged (1100ndash1320) and where the precursor material was
filled into containers and weighed (1320ndash1520) and outdoors (1100ndash1520)
dN
dlo
gD
p[p
arti
cles
cm
3] ELPI
OPC
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
Before bagging of LiFePO4
During bagging of LiFePO4
Before bagging of LiFePO4
During bagging of LiFePO4
Figure 4 Particle size distributions during and before the bagging of LiFePO4 Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
5
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
ELPI
OPC
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
Figure 5 Particle size distributions during and before the filling and weighing of the precursor
material Particle sizes are expressed in terms of aerodynamic diameter for ELPI and optical
diameter for OPC
313 Bagging of ZnO Figure 6 shows the changes in the particle number concentrations measured by
the CPCs and OPCs near the work area and outdoors during the bagging of ZnO (1000ndash1300) The
number concentrations of micron-sized particles were slightly higher near the work area than outdoors
Figure 7 shows the particle size distributions during the bagging of ZnO (highest 10-s-average
concentration at 1115) and before it (ie the average concentration in the period 955ndash1000) near the
work area measured by the ELPI and OPC The number concentrations of micron-sized particles
during the bagging of ZnO were slightly higher than those before
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
6
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
electrical low-pressure impactor (ELPI Dekati Ltd Finland aerodynamic diameters of 7ndash10000 nm
12 channels) A stainless pipe and conductive silicone tubing were used to transmit the particles from
the sampling point around the work area to the measuring instruments The sampling flow rates of the
CPC OPC and ELPI were 07 28 and 10 Lmin respectively and the average time was 10 s per
sample
22 Filter sampling and electron microscope observation
The aerosol particles were collected on a Nuclepore membrane filter (diameter of 25 mm pore size of
0080 microm Nomura Micro Science Co Ltd Japan) with a stainless steel filter holder (available
filtration area of 380 mm2 KS-25F Advantec Toyo Kaisha Ltd Japan) for electron microscopy
analysis The sampling flow rate was set at approximately 1ndash2 Lmin A stainless pipe and conductive
silicone tubing were used to transmit the particles from the sampling point around the work area to the
sampling filter
The aerosol particles collected on the Nuclepore filters were observed using a field-emission
scanning electron microscope (SEM S-4300 Hitachi High-Technologies Corporation Japan) under
an accelerating voltage of 1 kV Before the SEM observation the samples mounted on SEM grids
were coated with platinumndashpalladium (approximately 1 nm) to avoid image charging
23 Processes investigated
We performed onsite aerosol measurement for ENMs at industrial plants manufacturing ENMs during
the following processes
231 Collection of SiC from synthesis reactors During the collection of SiC from two reactors after
synthesis by thermal plasma chemical vapor deposition the aerosol particles at a site near to the work
area (approximately 50ndash100 cm) and at a site far from the work area (approximately 5 m) were
measured simultaneously Because the room had a ventilation system with a high efficiency particulate
air (HEPA) filter the aerosol particle concentrations in the room during nonworking periods were
generally low The representative characteristics of SiC provided by the manufacturer are as follows
the average primary particle diameter is 30 nm and the specific surface area is 50 m2g
232 Synthesis and bagging of LiFePO4 LiFePO4 which is used as the cathode materials in lithium-
ion batteries is synthesized by sintering a precursor material the nature of this material is
confidential Aerosol particles were measured at a distance of approximately 60 cm from the work
area where the synthesized LiFePO4 was being bagged (1100ndash1320) and approximately 100 cm from
the work area where the precursor material was being filled into containers and weighed (1320ndash
1520) In addition the aerosol particles in the air entering through the outside air intake were
simultaneously measured Both LiFePO4 and precursor material mainly consist of the primary particles
with a diameter of approximately a hundred to a few hundred nanometers
233 Bagging of ZnO When the synthesized ZnO was being bagged aerosol particles at a distance
of approximately 50ndash100 cm from the work area and outdoors were measured simultaneously
Although the hoppers of ZnO were automatically emptied into drums which were lined with plastic
bags the processes of disconnecting the bags containing the synthesized ZnO from the hopper outlets
sealing the bags and connecting the empty bags in the drums to the hopper outlets were performed
manually The bagging began at 1000 and ZnO was filled into ten drums during a period of three
hours ie till 1300 The primary particle diameter was a few tens of nanometers as observed through
the SEM (see section 32)
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
2
3 Results
31 Particle number concentrations and size distributions of released airborne ENMs
311 Collection of SiC from synthesis reactors Figure 1 shows the changes in the particle number
concentrations measured by the CPCs and OPCs When collecting SiC from the two synthesis reactors
(first 1054ndash1105 and second 1110ndash1117) the number concentrations of micron-sized particles
increased whereas those of nano- and submicron-sized particles did not
Figure 2 shows the particle size distributions during the SiC collection (highest 10-s-average
concentration at 1110) and before it (ie the average concentration in the period 1042ndash1054) at the
site near to the work area measured by the ELPI and OPC Figure 2 indicates that the number
concentrations of particles with a diameter greater than a few hundred nanometers were higher during
the collection process than before
0
500
1000
1500
2000
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
0
5
10
15
20
0
5
10
15
20
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
1
2
3
4
5
6
0
1
2
3
4
5
6
Collection Collection
Site near to work area
Site far from work area
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Site near to work area
Site far from work area
Site near to work area
Site far from work area
Figure 1 Changes in the particle number concentrations at a site near to and at a site far from
the work area where SiC was collected from the synthesis reactors
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
3
0001
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
ELPI
OPC
Before SiC collection
During SiC collection
Before SiC collection
During SiC collection
Figure 2 Particle size distributions during and before the collection of SiC Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
312 Synthesis and bagging of LiFePO4 Figure 3 shows the changes in the particle number
concentrations measured by the CPCs and OPCs near the work areas where the synthesized LiFePO4
was bagged (1100ndash1320) and where the precursor material was filled into containers and weighed
(1320ndash1520) and outdoors (1100ndash1520) The number concentrations of submicron- and micron-
sized particles increased when a bag containing LiFePO4 was being disconnected from the hopper
outlet and sealed (1135 and 1250) and when filling and weighing the precursor material (1140ndash
1152 1400ndash1424)
Figure 4 shows the particle size distributions during the bagging of LiFePO4 (highest 10-s-average
concentration at 1135) and before it (ie the average concentration in the period 1120ndash1134) near
the work area measured by ELPI and OPC Figure 5 shows the particle size distributions during the
filling and weighing of the precursor material (ie the average concentration in the period 1400ndash
1424) and before it (ie the average concentration in the period 1350ndash1400) near the work area
measured by the ELPI and OPC Figures 4 and 5 indicate that the number concentrations of particles
with a diameter greater than several hundred nanometers increased when LiFePO4 was being bagged
and when filling and weighing the precursor material
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
4
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
100
50
150
0
100
50
150 Bagging of
LiFePO4
Filling and weighing
of precursor material
0
100
50
150
200
0
10000
20000
30000
0
10000
20000
30000
1100 1200 1300 1400 15001100 1200 1300 1400 1500
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Filling and weighing
of precursor material
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 3 Changes in the particle number concentrations near the work areas where
synthesized LiFePO4 was bagged (1100ndash1320) and where the precursor material was
filled into containers and weighed (1320ndash1520) and outdoors (1100ndash1520)
dN
dlo
gD
p[p
arti
cles
cm
3] ELPI
OPC
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
Before bagging of LiFePO4
During bagging of LiFePO4
Before bagging of LiFePO4
During bagging of LiFePO4
Figure 4 Particle size distributions during and before the bagging of LiFePO4 Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
5
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
ELPI
OPC
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
Figure 5 Particle size distributions during and before the filling and weighing of the precursor
material Particle sizes are expressed in terms of aerodynamic diameter for ELPI and optical
diameter for OPC
313 Bagging of ZnO Figure 6 shows the changes in the particle number concentrations measured by
the CPCs and OPCs near the work area and outdoors during the bagging of ZnO (1000ndash1300) The
number concentrations of micron-sized particles were slightly higher near the work area than outdoors
Figure 7 shows the particle size distributions during the bagging of ZnO (highest 10-s-average
concentration at 1115) and before it (ie the average concentration in the period 955ndash1000) near the
work area measured by the ELPI and OPC The number concentrations of micron-sized particles
during the bagging of ZnO were slightly higher than those before
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
6
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
3 Results
31 Particle number concentrations and size distributions of released airborne ENMs
311 Collection of SiC from synthesis reactors Figure 1 shows the changes in the particle number
concentrations measured by the CPCs and OPCs When collecting SiC from the two synthesis reactors
(first 1054ndash1105 and second 1110ndash1117) the number concentrations of micron-sized particles
increased whereas those of nano- and submicron-sized particles did not
Figure 2 shows the particle size distributions during the SiC collection (highest 10-s-average
concentration at 1110) and before it (ie the average concentration in the period 1042ndash1054) at the
site near to the work area measured by the ELPI and OPC Figure 2 indicates that the number
concentrations of particles with a diameter greater than a few hundred nanometers were higher during
the collection process than before
0
500
1000
1500
2000
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
0
5
10
15
20
0
5
10
15
20
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
1
2
3
4
5
6
0
1
2
3
4
5
6
Collection Collection
Site near to work area
Site far from work area
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
1040 1050 1100 1110 1120 1130 11401040 1050 1100 1110 1120 1130 1140
Site near to work area
Site far from work area
Site near to work area
Site far from work area
Figure 1 Changes in the particle number concentrations at a site near to and at a site far from
the work area where SiC was collected from the synthesis reactors
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
3
0001
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
ELPI
OPC
Before SiC collection
During SiC collection
Before SiC collection
During SiC collection
Figure 2 Particle size distributions during and before the collection of SiC Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
312 Synthesis and bagging of LiFePO4 Figure 3 shows the changes in the particle number
concentrations measured by the CPCs and OPCs near the work areas where the synthesized LiFePO4
was bagged (1100ndash1320) and where the precursor material was filled into containers and weighed
(1320ndash1520) and outdoors (1100ndash1520) The number concentrations of submicron- and micron-
sized particles increased when a bag containing LiFePO4 was being disconnected from the hopper
outlet and sealed (1135 and 1250) and when filling and weighing the precursor material (1140ndash
1152 1400ndash1424)
Figure 4 shows the particle size distributions during the bagging of LiFePO4 (highest 10-s-average
concentration at 1135) and before it (ie the average concentration in the period 1120ndash1134) near
the work area measured by ELPI and OPC Figure 5 shows the particle size distributions during the
filling and weighing of the precursor material (ie the average concentration in the period 1400ndash
1424) and before it (ie the average concentration in the period 1350ndash1400) near the work area
measured by the ELPI and OPC Figures 4 and 5 indicate that the number concentrations of particles
with a diameter greater than several hundred nanometers increased when LiFePO4 was being bagged
and when filling and weighing the precursor material
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
4
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
100
50
150
0
100
50
150 Bagging of
LiFePO4
Filling and weighing
of precursor material
0
100
50
150
200
0
10000
20000
30000
0
10000
20000
30000
1100 1200 1300 1400 15001100 1200 1300 1400 1500
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Filling and weighing
of precursor material
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 3 Changes in the particle number concentrations near the work areas where
synthesized LiFePO4 was bagged (1100ndash1320) and where the precursor material was
filled into containers and weighed (1320ndash1520) and outdoors (1100ndash1520)
dN
dlo
gD
p[p
arti
cles
cm
3] ELPI
OPC
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
Before bagging of LiFePO4
During bagging of LiFePO4
Before bagging of LiFePO4
During bagging of LiFePO4
Figure 4 Particle size distributions during and before the bagging of LiFePO4 Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
5
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
ELPI
OPC
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
Figure 5 Particle size distributions during and before the filling and weighing of the precursor
material Particle sizes are expressed in terms of aerodynamic diameter for ELPI and optical
diameter for OPC
313 Bagging of ZnO Figure 6 shows the changes in the particle number concentrations measured by
the CPCs and OPCs near the work area and outdoors during the bagging of ZnO (1000ndash1300) The
number concentrations of micron-sized particles were slightly higher near the work area than outdoors
Figure 7 shows the particle size distributions during the bagging of ZnO (highest 10-s-average
concentration at 1115) and before it (ie the average concentration in the period 955ndash1000) near the
work area measured by the ELPI and OPC The number concentrations of micron-sized particles
during the bagging of ZnO were slightly higher than those before
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
6
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
0001
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
ELPI
OPC
Before SiC collection
During SiC collection
Before SiC collection
During SiC collection
Figure 2 Particle size distributions during and before the collection of SiC Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
312 Synthesis and bagging of LiFePO4 Figure 3 shows the changes in the particle number
concentrations measured by the CPCs and OPCs near the work areas where the synthesized LiFePO4
was bagged (1100ndash1320) and where the precursor material was filled into containers and weighed
(1320ndash1520) and outdoors (1100ndash1520) The number concentrations of submicron- and micron-
sized particles increased when a bag containing LiFePO4 was being disconnected from the hopper
outlet and sealed (1135 and 1250) and when filling and weighing the precursor material (1140ndash
1152 1400ndash1424)
Figure 4 shows the particle size distributions during the bagging of LiFePO4 (highest 10-s-average
concentration at 1135) and before it (ie the average concentration in the period 1120ndash1134) near
the work area measured by ELPI and OPC Figure 5 shows the particle size distributions during the
filling and weighing of the precursor material (ie the average concentration in the period 1400ndash
1424) and before it (ie the average concentration in the period 1350ndash1400) near the work area
measured by the ELPI and OPC Figures 4 and 5 indicate that the number concentrations of particles
with a diameter greater than several hundred nanometers increased when LiFePO4 was being bagged
and when filling and weighing the precursor material
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
4
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
100
50
150
0
100
50
150 Bagging of
LiFePO4
Filling and weighing
of precursor material
0
100
50
150
200
0
10000
20000
30000
0
10000
20000
30000
1100 1200 1300 1400 15001100 1200 1300 1400 1500
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Filling and weighing
of precursor material
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 3 Changes in the particle number concentrations near the work areas where
synthesized LiFePO4 was bagged (1100ndash1320) and where the precursor material was
filled into containers and weighed (1320ndash1520) and outdoors (1100ndash1520)
dN
dlo
gD
p[p
arti
cles
cm
3] ELPI
OPC
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
Before bagging of LiFePO4
During bagging of LiFePO4
Before bagging of LiFePO4
During bagging of LiFePO4
Figure 4 Particle size distributions during and before the bagging of LiFePO4 Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
5
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
ELPI
OPC
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
Figure 5 Particle size distributions during and before the filling and weighing of the precursor
material Particle sizes are expressed in terms of aerodynamic diameter for ELPI and optical
diameter for OPC
313 Bagging of ZnO Figure 6 shows the changes in the particle number concentrations measured by
the CPCs and OPCs near the work area and outdoors during the bagging of ZnO (1000ndash1300) The
number concentrations of micron-sized particles were slightly higher near the work area than outdoors
Figure 7 shows the particle size distributions during the bagging of ZnO (highest 10-s-average
concentration at 1115) and before it (ie the average concentration in the period 955ndash1000) near the
work area measured by the ELPI and OPC The number concentrations of micron-sized particles
during the bagging of ZnO were slightly higher than those before
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
6
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
100
50
150
0
100
50
150 Bagging of
LiFePO4
Filling and weighing
of precursor material
0
100
50
150
200
0
10000
20000
30000
0
10000
20000
30000
1100 1200 1300 1400 15001100 1200 1300 1400 1500
1100 1200 1300 1400 15001100 1200 1300 1400 1500
Filling and weighing
of precursor material
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 3 Changes in the particle number concentrations near the work areas where
synthesized LiFePO4 was bagged (1100ndash1320) and where the precursor material was
filled into containers and weighed (1320ndash1520) and outdoors (1100ndash1520)
dN
dlo
gD
p[p
arti
cles
cm
3] ELPI
OPC
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
Before bagging of LiFePO4
During bagging of LiFePO4
Before bagging of LiFePO4
During bagging of LiFePO4
Figure 4 Particle size distributions during and before the bagging of LiFePO4 Particle sizes
are expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
5
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
ELPI
OPC
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
Figure 5 Particle size distributions during and before the filling and weighing of the precursor
material Particle sizes are expressed in terms of aerodynamic diameter for ELPI and optical
diameter for OPC
313 Bagging of ZnO Figure 6 shows the changes in the particle number concentrations measured by
the CPCs and OPCs near the work area and outdoors during the bagging of ZnO (1000ndash1300) The
number concentrations of micron-sized particles were slightly higher near the work area than outdoors
Figure 7 shows the particle size distributions during the bagging of ZnO (highest 10-s-average
concentration at 1115) and before it (ie the average concentration in the period 955ndash1000) near the
work area measured by the ELPI and OPC The number concentrations of micron-sized particles
during the bagging of ZnO were slightly higher than those before
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
6
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
001
01
1
10
100
1000
10000
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
art
icle
scm
3]
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
ELPI
OPC
Before filling and weighing
of precursor material
During filling and weighing
of precursor material
Figure 5 Particle size distributions during and before the filling and weighing of the precursor
material Particle sizes are expressed in terms of aerodynamic diameter for ELPI and optical
diameter for OPC
313 Bagging of ZnO Figure 6 shows the changes in the particle number concentrations measured by
the CPCs and OPCs near the work area and outdoors during the bagging of ZnO (1000ndash1300) The
number concentrations of micron-sized particles were slightly higher near the work area than outdoors
Figure 7 shows the particle size distributions during the bagging of ZnO (highest 10-s-average
concentration at 1115) and before it (ie the average concentration in the period 955ndash1000) near the
work area measured by the ELPI and OPC The number concentrations of micron-sized particles
during the bagging of ZnO were slightly higher than those before
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
6
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
Nu
mb
er c
once
ntr
atio
n
[par
ticl
esc
m3]
CPC 10ndashgt1000 nm
OPC 300ndash500 nm
OPC 1000ndash3000 nm
0
2
4
6
1
3
5
0
2
4
6
1
3
5
0
20000
40000
60000
80000
0
20000
40000
60000
80000
Bagging start
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
0
50
100
150
200
250
300
0
50
100
150
200
250
300
Near work area
Outdoors
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
930 1000 1100 1200 13001030 1130 1230930 1000 1100 1200 13001030 1130 1230
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Near work area
Outdoors
Figure 6 Changes in the particle number concentrations near the work area and outdoors
during the bagging of ZnO
10 100 1000 10000
Particle diameter (Dp) [nm]
dN
dlo
gD
p[p
arti
cles
cm
3]
ELPI
OPC
01
1
10
100
1000
10000
100000
During bagging of ZnO
Before bagging of ZnO
During bagging of ZnO
Before bagging of ZnO
Figure 7 Particle size distributions during and before the bagging of ZnO Particle sizes are
expressed in terms of aerodynamic diameter for ELPI and optical diameter for OPC
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
7
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8
32 Morphology of released airborne ENMs
Figure 8 shows the SEM images of the aerosol particles collected during each process A large number
of submicron- and micron-sized ENM aggregatesagglomerates were observed
5 microm
5 microm
5 microm
A B
C
Figure 8 SEM images of the aerosol particles collected during each process
A Collection of SiC from synthesis reactors B Synthesis and bagging of LiFePO4
C Bagging of ZnO
4 Conclusions
In onsite aerosol measurements for ENMs at industrial manufacturing plants increases in the number
concentrations of submicron- and micron-sized aerosol particles were generally observed whereas few
increases in the number concentrations of nanosized particles were observed Although the relatively
high background concentration of nanosized aerosol particles may have prevented the detection of a
small amount of released nanosized aerosol particles we can at least be certain that the number
concentration of nanosized particles released during these processes was substantially lower than the
background concentration In the SEM observations of the aerosol particles collected during each
process a large number of submicron- and micron-sized ENM aggregatesagglomerates were
observed
Acknowledgment
This work was funded by the New Energy and Industrial Technology Development Organization of
Japan (NEDO) under a grant for ldquoEvaluating risks associated with manufactured nanomaterialsrdquo (no
P06041) We would like to express our gratitude to Sumitomo Osaka Cement Co Ltd for their
cooperation during the onsite measurements We wish to thank the researchers participating in the
JNIOSH project ldquoOccupational Health Issue of Nanotechnology Industryrdquo for their cooperation
References
[1] Oberdoumlrster G Oberdoumlrster E and Oberdoumlrster J 2005 Environ Health Perspect 113 823
[2] Maynard A D 2006 Nano Today 1 22
Nanosafe2010 International Conference on Safe Production and Use of Nanomaterials IOP PublishingJournal of Physics Conference Series 304 (2011) 012004 doi1010881742-65963041012004
8