optics and image quality in the human eyeroorda.vision.berkeley.edu/pubs/optics_of_the_eye.pdfthe...
TRANSCRIPT
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Optics and Image Quality in the Human Eye
Austin Roorda, PhDBraff Chair in Clinical Optometric Sciences
University of California, BerkeleySchool of Optometry
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• email: [email protected]
• google: Austin Roorda
all slides (in color) are available on the web at • vision.berkeley.edu/roordalab/• link to courses/resources on left menubar
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Part 1 The Optics of the Eye
(NOTE: sections 1.1 and 1.2 will not be covered in the lecture. They are included
for your reference)
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n
F F’CA
rn’
f f’
F nf
=−
fnF′′
=′ Rr
=1
Refraction and Image Formation
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n
L L’CA
rn’
l l’
rnn
ln
ln −′
+=′′
′ =′′
L nl
L nl
=′ = +
′ −L L n nr
define:
object vergence at surface
image vergence at surface
Refraction and Image Formation
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n
F F’CA
rn’
f’
′ =′ −F n nr
special case 1: object at infinity => L = 0 & L’=F’
Refraction and Image Formation
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n
F F’CA
rn’
f
F n nr
F=′ −
= ′
special case 2: image at infinity => L’ = 0 & L=-F
′ = + ′L L F
Refraction and Image Formation
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mm 22.22 =′∴′′
=′ ffnF
To simplify image formation in the eye we use the reduced eye. The reduced eye has a single refracting surface
n’=4/3n’=1
F=60 D
1.2 The reduced eye
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FLL +=′
ee FKKFKK −′=⇒+=′
By definition, in the human eye
In the reduced eye,k (far point) and k’ are measured from the
refracting surface.
1.2 The reduced eye
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Cornea (first surface)
transition from air (n =1)to front surface ofcornea (n = 1.376)
radius of curvature = 7.7 mm
power:
1.3 Components of the human optical system
′ =′ −
=−
= +
F n nr
1376 10077
48 83
..
. D
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Cornea (second surface)
Transition from back surfaceof cornea (n = 1.376) to theaqueous humor (n = 1.336)radius of curvature = 6.8 mm
power:
total power of cornea ~ +43 D
1.3 Components of the human optical system
D 88.50068.
376.1336.1
−=
−=
−′=′
rnnF
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The Pupil is affected by:
light conditions attentionemotionage
Function:
govern image qualitydepth of focuscontrol light level?
1.3 Components of the human optical system
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• Stimulus Variables– light level– spectral composition– spatial configurations
• field size• spatial structure of field
– monocular/binocular view– accommodative state– non-visual stimuli
• pain• noise
• Observer Variables– individual differences– age– day-to-day within observer variance– biomechanical factors
• respiration• heart beat
– cognitive factors• arousal, attention, fright• workload• hedonistic content
Pokorny and Smith, 1997
Factors affecting pupil size
1.3 Components of the human optical system
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The pupil is perfectly located to maximize the field of view of the eye
Recall that the ½-illumination field of view is defined as the angle subtended from the center of the entrance pupil to the edges of the field stop.
Aperture stop
Entrance pupil
Extremely wide field of view
.Cornea
1.3 Components of the human optical system
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The range of luminances in the environment is enormous!1.3 Components of the human optical system
Rodieck, B. The First Steps in Seeing
luminance (cd/m2)
10-6 10-5 10-4 10-3 10-2 10-1 1 10 102 103 104 105 106 107 108 109 1010
rod threshhold
clear blue sky
snowin
sunlight
solardisc
darkest sky
white paper illuminated by a
full moon
cinema screen
computer monitor
surface of the moon
fluorescent bulb
incandescent light filament
retinal damage threshold (depends
on pupil size)
floodlit buildingsstatues
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Crystalline Lens
Gradient index of refractionn = 1.385 at surfacesn = 1.375 at the equatorn ~= 1.41 at the center
Little refraction takes place atthe surface but instead the light curves as it passes through.
For a homogenous lens to have same power, the overall indexwould have to be greater than thepeak index in the gradient.
total power of lens ~= 21 D
1.3 Components of the human optical system
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courtesy of Adrian Glasser, PhD
1.3 Components of the human optical system
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Accommodation
The relaxed eye is under tensionat the equator from the ciliary body.This keeps the surfaces flatenough so that for a typical eyedistant objects focus onthe retina.
1.3 Components of the human optical system
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Accommodation
In the accommodated eye, the ciliary muscle constrictsand relaxes the tension onthe equator of the lens.
Surface curvature increases.
Power of the lens increases.
Power of the accommodated lens ~= 32.31 D
1.3 Components of the human optical system
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1.3 Components of the human optical system
Accommmodation
• The eye needs ~ 60D of power to focus light from infinity onto its retina– 1.33/60 = .02217 m = 22.17 mm
• Any extra power offered by the lens allows the eye to focus on near objects. – 8 D of extra power allows the eye to focus on
objects as close as 1/8 = 0.125m = 12.5 cm
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Retina:
Images are sampled by millions of rods and cones.
fovea: 5 degrees from optical axisoptic disc: 15 deg from fovea,10 deg from optical axis.
1.3 Components of the human optical system
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It is the angle subtended at the second nodal point by the imageIt is also equal to the angle subtended at the first nodal point by the object
The nodal points are points in the optical system where the light passing through emerges at the same angle
The second nodal point in the eye is about 16.5 mm from the retina
Consider a 1 mm image on the retina…
1.3 Components of the human optical systemWhat is Visual Angle?
N’N
θ/2θ/2 1mm
o
0.5tan 1.732 16.5 2
visual angle = =3.47an object subtending 3.47 deg makes a 1 mm image on the retina an object subtending 1 makes and image that is 288 across
o
o m
θ θ
θ
µ
= ⇒ =
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1.3 Components of the human optical system
• 1 radian = 57.29 degrees• 1 degree = .0174 radians = 17.4 mrad• 1 minute = .29 mrad• 1 mrad = 3.44 minutes• 1 minute = 4.8 microns (depends on axial length)
• 1 foveal cone = 2.5 microns (with intersubject variability)
Visual Angle
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1.3 Components of the human optical system
Because small angle approximations require the units to be in radians.
( )
( )
sin for small angleseg. first try using degrees..sin 1 0.017now try using radians...sin 0.017453 0.017452
θ θ≅
=
=
Why Radians?
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1.3 Components of the human optical system Visual Angle: ‘Handy’ guide
*viewed at arms-length
fingernail~1 deg*
fist~10 deg*
moon (& sun)0.5 deg
20/20 E5 arcmin**
20/10 E2.5 arcmin**
**1 degree = 60 arcmin
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1 foveal cone = ~2.5 microns = ~0.5 arcmin
1.3 Components of the human optical system
1 deg = ~288 microns
Visual Angle
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1 foveal cone = ~2.5 microns = ~0.5 arcmin
20/20 letter= 5 arcmin
1.3 Components of the human optical system Visual Angle
1 deg = ~288 microns
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1 foveal cone = ~2.5 microns = ~0.5 arcmin
20/10 letter= 2.5 arcmin
1.3 Components of the human optical system Visual Angle
1 deg = ~288 microns
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1 foveal cone = ~2.5 microns = ~0.5 arcmin
Moon= 30 arcmin
1.3 Components of the human optical system Visual Angle
1 deg = ~288 microns
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1.3 Components of the human optical system
N’N
optical axis
C1
L1 L2
ακ
C1L1
L2H H’
centers of curvature
λ
fixated object
Axes in the Eye
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1.3 Components of the human optical system
• Optical axis: best line joining the centers of curvatures of the optical surfaces– Some definitions choose to weight the centers of curvature by the
respective powers of the components• Visual axis: line from fovea through the nodal points• Line of sight: line from object through center of entrance pupil that
reaches the fovea (chief ray)• Pupillary axis: line from center of curvature of corneal first surface
with pupil center• Angle alpha: angle between optical axis and visual axis• Angle kappa: angle between pupillary axis and visual axis (angle
kappa is easily observed as a displacement of the coaxially viewed corneal reflex from the pupil center of a fixating eye)
• Angle lambda: angle between pupillary axis and line of sight
Visual axis and line of sight are often assumed to be parallel, which is only true for distant objects
Axes and Angles in the Eye
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optic disc
foveaposterior pole
5 deg10 deg
1.3 Components of the human optical system
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1.3 Components of the human optical system
020000400006000080000
100000120000140000160000180000
-25 -20 -15 -10 -5 0 5 10 15 20retinal eccentricity (mm)
spat
ial d
ensit
y (#
/mm
2)
conesrods
Osterberg, Acta Ophthalmologica, 6:1-103, 1935
Curcio et al, Journal of Comparative Neurology, 292:497-523, 1990
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1.3 Components of the human optical system
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Relative Spectral Absorptance
wavelength (nm)
norm
alize
d sp
ectra
l abs
orpt
ance
0.00
0.25
0.50
0.75
1.00
400 450 500 550 600 650 700
L conesM conesS conesrods
1.3 Components of the human optical system
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5 arc min
JW 1 deg nasal JW 1 deg temporal
AN 1 deg nasal macaque 1.4 deg nasal
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Boettner and Wolter, 1962
1.4 Transmission of the Ocular Media
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Lens Optical Density Increases with Age
figure from Wyszecki and Stiles, 1982
1.4 Transmission of the Ocular Media
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1.4 Transmission of the Ocular Media
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“Now, it is not too much to say that if an optician wanted to sell me an instrument which had all these defects, I should think myself quite justified in blaming his carelessness in the strongest terms and giving him back his instrument”
Helmholtz (1881) on the eye’s optics.
Part 2 Image Quality in the Eye
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2 mm 4 mm 6 mm
2.1 Blur, Defocus and Pupil Size
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2 mm pupil 4 mm pupil 6 mm pupil
In focus
Focused in front of retina
Focused behind retina
2.1 Blur, Defocus and Pupil Size
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2.1 Depth of focus is a function of pupil size
blur[mrad] [ ]blur[minutes] 3.44 [ ]
D pupilsize mmD pupilsize mm
= ×= × ×
where D is the defocus in diopters
Computation of Geometric Blur Size
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2.1 Depth of focus is a function of pupil size
lx
θW
( ) ( ) ( )2
By similar triangles...
use small angle approximation to get...
1 1
where is defocus in diopters
W bl x x
W ll x x
Wx x l l l l xW W W WDl lx l l x l l x l l x l x l
D
θ
θ
=−
=−
− + − = = = − = − = − − − − −
b
Derivation of Geometric Blur Size Eqn.
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Application of Blur Equation
• 1 D defocus, 8 mm pupil produces 27.52 minute blur size ~ 0.5 degrees
2.1 Depth of focus is a function of pupil size
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2.1 Depth of focus is a function of pupil size
Draw a cross like this one on a page. Hold it so close that is it completely out of focus, then squint. You should see the horizontal line become clear. The line becomes clear because you have used your eyelids to make your effective pupil size smaller, thereby reducing the blur due to defocus on the retina image. Only the horizontal line appears clear because you have only reduced the blur in the horizontal direction.
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2.1 Blur, Defocus and Pupil Size
=
=
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2.1 Depth of focus is a function of pupil size
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“Any deviation of light rays from a rectilinear path which cannot be interpreted as reflection or refraction”
Sommerfeld, ~ 1894
2.2 Diffraction and Interference
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2.2 Diffraction and Interference
• diffraction causes light to bend perpendicular to the direction of the diffracting edge
• interference causes the diffracted light to have peaks and valleys
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2.2 Diffraction and Interference
• Also called far-field diffraction• Occurs when the screen is held far from the aperture.
• Occurs at the focal point of a lens!
Fraunhofer Diffraction
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rectangular aperture
square aperture
2.2 Diffraction and InterferenceFraunhofer Diffraction
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???
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Airy Disc
circular aperture
2.2 Diffraction and Interference
Sir George Biddel Airy: Inventor of spectacles for astigmatism
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The Point Spread Function, or PSF, is the image that an optical system forms of a point source.
The point source is the most fundamental object, and forms the basis for any complex object.
The PSF is analogous to the Impulse Response Function in electronics.
2.3 The Point Spread Function
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Airy Disc
The PSF for a perfect optical system is the Airy disc, which is the Fraunhofer diffraction pattern
for a circular pupil.
2.3 The Point Spread Function
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θ
1.22aλθ ⋅
=N’
angle subtended at the nodal point
wavelength of the light
pupil diametera
θ
λ
≡
≡
≡
2.3 The Point Spread FunctionThe Airy Disc
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=
angle between peak and first minimum (in radians!)
wavelength of the light
pupil diameter
1801 radian degrees
1 degree = 60 minutes of arc1 minute of arc = 60 seconds of arc
1.22
a
aθ
λ
π
λθ
≡
≡
≡
⋅=
2.3 The Point Spread FunctionThe Airy Disc
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1 mm 2 mm 3 mm 4 mm 5 mm 6 mm 7 mm
Diffraction-limited Eye
2.3 The Point Spread FunctionPSF vs. Pupil Size: Perfect Eye
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2.4 Resolution
Rayleigh resolution
limit
Unresolved point sources
Resolved
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min
min
angle subtended at the nodal point
wavelength of the light
pupil diameter
1.22
a
aθ
λ
λθ
≡
≡
≡
⋅=
0
0.5
1
1.5
2
2.5
1 2 3 4 5 6 7 8
pupil diameter (mm)
min
imum
ang
le o
f res
olut
ion
(min
utes
of a
rc 5
00 n
m li
ght)
2.4 Resolution
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2.4 Resolution
=
min
min
angle subtended at the nodal point
180 1.2260a
θ
λθπ
≡
⋅= × ×
5 ar
cmin
2.5
arcm
in
20/2
020
/10 PSF
2mm pupil550 nm
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Keck telescope: (10 m reflector)
9
min1.22 1.22 900 10
10109.8 nanoradians0.023 seconds of arc
aλθ
−⋅ ⋅ ×= =
==
> 2500 times better than the eye!
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2.5 Light scatter in the human eye
slides courtesy of Thomas J. T. P. van den Berg
The Netherlands Ophthalmic Research Institute of the Royal Netherlands Academy of Arts and Sciences,
Amsterdam, The Netherlands;
Published in:
van den Berg TJ, Hagenouw MP, Coppens JE. The ciliary corona: physical model and simulation of the fine needles radiating from point light sources. Invest Ophthalmol Vis Sci 2005; 46(7):2627-2632.
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Tom van den Berg
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Sources of Scatter
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Tom van den Berg
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Ciliary corona
Actual subjective appearance of straylight: a pattern of very fine streaks, not at all like the circularly uniform (Airy disc-like) scattering pattern of particles of
approximate wavelength size
Tom van den Berg
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Effect of Scatter on Retinal Surface
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Tom van den Berg
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Tom van den Berg
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2.5 Straylight (Glare) Equation
n
AEIθ
=where I is the retinal illuminance at the distance θ from the glare source of illuminance E. A is a scaling constant. n is usually calculated to be 2.
0
0.005
0.01
0.015
0.02
0.025
0 2 4 6 8 10 12distance from glare source on retina (degrees)
frac
tion
of p
eak
inte
nsity
Equation applies outside of about 1 degree from the glare source.Although 1% at 1 degree seems small, the total flux in the annulus outside of 1 degree can amount to 10% or more.
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Longitudinal Chromatic Aberration
Blue focus
Red focus
2.6 Chromatic Aberration
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Lateral Chromatic Aberration
2.6 Chromatic Aberration
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2.6 Chromatic Aberration
Fig. 1. Chromatic difference of refraction from three experimental studies2–4 in the visible spectrum and best-fit Cauchy equation (5a), Cornu’s equation (5c), and Herzberger’s equation to the combined studies. All data were set to be zero at 590 nm. Results of three studies6–8 with measurements in the infrared are also shown; we moved the data from these studies studies to coincide with Eq. (5a) at the lower wavelength (543 nm, Refs. 6 and 7) or at the lowest wavelength (700 nm, Ref. 8). Where shown, error bars indicate standard deviations.
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Thibos, Bradley & Zhang, 1989
2.6 Chromatic Aberration
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2.6 Chromatic Aberration
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Perfect Eye(limited only by diffraction)
2.7 Monochromatic Aberrations
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Aberrated Eye
2.7 Monochromatic Aberrations
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“I have never experienced any inconvenience from this imperfection, nor did I ever discover it till I made these experiments; and I believe I can examine minute objects with as much accuracy as most of those whose eyes are differently formed”
Thomas Young (1801) on his own aberrations.
2.8 The Total Aberrations of the Eye
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Change in the line spread function with
pupil size
Campbell & Gubisch, 1966
2.8 The Total Aberrations of the Eye
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1 mm 2 mm 3 mm 4 mm 5 mm 6 mm 7 mm
Perfect Eye
Typical Eye
2.8 The Total Aberrations of the Eye
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1 2 3 4 5 6 7
1
0
-1
Pupil Size (mm)
Def
ocus
(D)
10 arcminutes
2.8 The Total Aberrations of the Eye
Diffraction-limited eye
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1 2 3 4 5 6 7
1
0
-1
Pupil Size (mm)
Def
ocus
(D)
10 arcminutes
Typical eye
2.8 The Total Aberrations of the Eye
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2.9 The Modulation Transfer Function, or MTF
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low medium high
object:100% contrast
image
spatial frequency
cont
rast
1
0
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2.9 The Modulation Transfer Function3D MTF
vertical spatial frequency (c/d) horizontal spatial
frequency (c/d)
0
0.2
0.4
0.6
0.8
1
0 50 100 150 200
Con
trast
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0 50 100 150 200 250
2.9 The Modulation Transfer Function
0
0.2
0.4
0.6
0.8
1 0 50 100 150 200 250
10 i
1 2 3 4 5 6 7 8
Con
trast
cut-off frequency
57.3cutoffafλ
=⋅
Rule of thumb: cutoff frequency increases by ~30 c/d for each mm increase in pupil size
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2.9 The Modulation Transfer Function
20/20 20/10
5 ar
cmin
2.5
arcm
in30 cyc/deg
60 cyc/deg
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0
0.2
0.4
0.6
0.8
1
0 50 100 150 200 250
1 mm2 mm3 mm4 mm5 mm6 mm7 mm8 mm
Spatial frequency (c/deg)
Mod
ulat
ion
trans
fer
2.9 The Modulation Transfer Function
20/20
20/10
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Change in MTF with pupil size
2.9 The Modulation Transfer Function
0
0.2
0.4
0.6
0.8
1
0 50 100 150 200 250
1 mm2 mm3 mm4 mm5 mm6 mm7 mm8 mm
Spatial frequency (cycles/degree)Imag
e co
ntra
st/o
bjec
t con
trast
perfect eyetypical eye
Rule of thumb: cutoff frequency increases by ~30 c/d for each mm increase in pupil size
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PSFs for the same eye
2.9 The Modulation Transfer Function
1 2 3 4 5 6 7 8
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2.10 The Phase Transfer Function, or PTF
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object
image
spatial frequency
phas
e sh
ift 180
0
-180
low medium high
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Phase Transfer Function
-150-100-50 0 50 100 150
-150
-100-50
050
100150 -150
-100
-50
0
50
100
150
-150-100-50 0 50 100 150
-150
-100-50
050
100
150 -150
-100
-50
0
50
100
150
phas
e sh
ift (d
egre
es)
0 50 100 150-180
-120
-60
0
60
120
180
0 50 100 150-180
-120
-60
0
60
120
180
phas
e sh
ift (d
egre
es)
spatial frequency (c/deg)spatial frequency (c/deg)
No AOrms: 0.29 µm
AO correctedrms: 0.09 µm
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2.11 Measurement of the wave aberrations of the eye
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2.11 What is the Wavefront?
converging beam=
spherical wavefront
parallel beam=
plane wavefront
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2.11 What is the Wavefront?
ideal wavefrontparallel beam=
plane wavefrontdefocused wavefront
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2.11 What is the Wavefront?
parallel beam=
plane wavefront aberrated beam=
irregular wavefront
ideal wavefront
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2.11 What is the Wavefront?
aberrated beam=
irregular wavefront
diverging beam=
spherical wavefront
ideal wavefront
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2.11 What is the Wave Aberration?diverging beam
=spherical wavefront wave aberration
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-3 -2 -1 0 1 2 3
-3
-2
-1
0
1
2
3
Wavefront Aberration
mm (right-left)m
m (s
uper
ior-i
nfer
ior)
2.11 What is the Wave Aberration?Wave Aberration of a Surface
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What are Zernike Polynomials?
• set of basic shapes that are used to fit the wavefront
• analogous to the parabolic x2 shape that can be used to fit 2D data
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Zernike Polynomials
1st order
2nd order
3rd order
4th order
5th order
high order aberrations
low order aberrations
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Properties of Zernike Polynomials
• orthogonal– terms are not similar in any way, so the weighting of one term
does not depend on whether or not other terms are being fit also• normalized
– the RMS wave aberration can be simply calculated as the vector of all or a subset of coefficients
• efficient– Zernike shapes are very similar to typical aberrations found in the
eye
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2.11.3 Relationships Between Wave Aberration,
PSF and MTF
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PSF(point spread function)
OTF (optical transfer function)
PTF (phase) MTF (contrast)
Image Quality Metrics
The reason we measure the wave aberration
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( )2 ( , )
, ( , )i W x y
i iPSF x y FT P x y eπλ
− =
( ) { }, ( , )x y i iMTF f f Amplitude FT PSF x y=
The PSF is the Fourier Transform (FT) of the pupil function
The MTF is the amplitude component of the FT of the PSF
( ) { }, ( , )x y i iPTF f f Phase FT PSF x y=
The PTF is the phase component of the FT of the PSF
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mm (right-left)-2 -1 0 1 2
-0.5
0
0.5
c/deg-100 0 100
0.2
0.4
0.6
0.8
c/deg-100 0 100
-0.5
0
0.5
arcsec-200 -100 0 100 200
Point Spread FunctionWavefront Aberration
Modulation Transfer Function Phase Transfer Function
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-200 -100 0 100 200
mm (right-left)
Wavefront Aberration
-2 -1 0 1 2-0.5
0
0.5
c/deg
Modulation Transfer Function
-100 0 100
0.2
0.4
0.6
0.8
c/deg
Phase Transfer Function
-100 0 100
-150
-100
-50
0
50
100
150
arcsec
Point Spread Function
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c/deg-100 0 100
-150
-100
-50
0
50
100
150
c/deg-100 0 100
0.2
0.4
0.6
0.8
mm (right-left)-2 -1 0 1 2
-0.5
0
0.5
1
1.5
-1000 -500 0 500 1000
Wavefront Aberration
Modulation Transfer Function Phase Transfer Functionarcsec
Point Spread Function
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Perfect Eye
Aberrated Eye
2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
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2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
rr’ r”
f f f f
p p’
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Perfect eye
Wavefront Lens Array CCD Array
Aberrated (typical) eye
2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
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2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
• The local slope (or the first derivative) of the wavefront is determined at each lenslet location
• The corresponding wavefront is determined by a least squares fitting of the slopes to the derivative of a polynomial selected to fit the wavefront
• Zernike polynomial is the most commonly used
Fitting the Wavefront
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2.11.4 Principles of the Shack-Hartmann Wavefront Sensor: The Lenslet Array
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Shack-Hartmann Images
BD KW SM
2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
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Wavefront Maps(at best focal plane)
BD KW SM
0.33 DS –0.17 DC X 87
6.42 DS –0.6 DC X 126
0 DS –1 DC X 3
2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
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Wavefront sensor image Wavefront aberration
Aberrations of an RK patient
2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
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Aberrations of a LASIK patientWavefront sensor image Wavefront aberration
2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
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Post - RK Post - LASIK
2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
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2.11.4 Principles of the Shack-Hartmann Wavefront Sensor
Keratoconus
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2.11.5 Metrics to Define Image Quality
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Wave Aberration Contour Map
-2 -1 0 1 2-2.5
-2
-1.5
-1
-0.5
0
0.5
1
1.5
2
mm (right-left)
mm
(sup
erio
r-inf
erio
r)
2.11.5 Metrics to Define Image Quality
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-0.5 0 0.5 1 1.5 2123456789
1011121314151617181920
Zern
ike te
rmCoefficient value (microns)
astig.defocus
astig.trefoilcomacomatrefoil
spherical aberration
2nd order
3rd order
4th order
5th order
Breakdown of Zernike Terms
2.11.5 Metrics to Define Image Quality
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2.11.5 Metrics to Define Image Quality
( ) ( )( )
( )( )
21 , ,
pupil area, wave aberration
, average wave aberration
RMS W x y W x y dxdyA
AW x y
W x y
= −
−
−
−
∫∫
Root Mean Square Wave Aberration
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2.11.5 Metrics to Define Image Quality
( ) ( ) ( ) ( )2 2 2 22 0 2 12 2 2 3 .......RMS Z Z Z Z− −= + + +
……
Include the terms for which you want to determine their impact (eg defocus and astigmatism only, third order terms or high order terms etc.)
Root Mean Square Wave Aberration
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2.11.5 Metrics to Define Image Quality
Point Spread Function
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2.11.5 Metrics to Define Image Quality
diffraction-limited PSF
Hdl
Heye
actual PSF
Strehl Ratio = eye
dl
HH
Strehl Ratio
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2.11.5 Metrics to Define Image Quality
00.10.20.30.40.50.60.70.80.9
1
0 50 100 150spatial frequency (c/deg)
cont
rast Area under the MTF
20/20 20/10
Modulation Transfer Function
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( , ) ( , ) ( , )PSF x y O x y I x y⊗ =
Convolution
2.12 Metrics to Define Image Quality
=
=works
the same for
inverse contrast!
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2.11.5 Metrics to Define Image Quality
20/40 letters
20/20 letters
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Typical Values for Wave Aberration
• Strehl ratios are about 5% for a 5 mm pupil that has been corrected for defocus and astigmatism.
• Strehl ratios for small (~ 1 mm) pupils approach 1, but the image quality is poor due to diffraction.
Strehl Ratio
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How bad is the eye? Static Aberrations
This metastudy compiles population statistics of over 1300 eyes collected
from 10 different labs
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How bad is the eye?: Static Aberrations
For the most part, aberrations in the eye are random. When you average enough eyes together, most terms are no different from zero. The only high order aberrations that is non-zero is spherical aberration, which averages to a small positive value.
Salmon & van de Pol, J Cataract Ref Surg, 2006
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How bad is the eye?: Static Aberrations
A population average of the magnitude of the Zernike terms shows that high order aberrations are dominated by 3rd order and spherical aberration.
Salmon & van de Pol, J Cataract Ref Surg, 2006
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How bad is the eye?: Static Aberrations
Like most optical systems, the aberrations diminish as the aperture is reduced.
But unlike turbulence from a telescope, the paraxial regions of the eye have lower aberrations than marginal locations (ie Fried’s parameter is not constant)
Salmon & van de Pol, J Cataract Ref Surg, 2006
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How bad is the eye?: Static Aberrations
Overall, the eye’s high order aberrations reduce with pupil size. The dashed line indicates the effective diffraction limit, according to Marachel’s criterion (RMS < λ/14) for 550 nm light.
Salmon & van de Pol, J Cataract Ref Surg, 2006
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Diaz-Santana et al. Benefit of higher closed-loop bandwidths in ocular adaptive optics, Opt Express, 11: (2003)
How bad is the eye?: Dynamic Aberrations
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• Dynamic Changes in the wave aberrations are caused by
– accommodation– eye movement– eye translation– tear film
2.12 Typical Values for Wave Aberration
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Change in aberrations with age
Monochromatic Aberrations as a Function of Age, from Childhood to Advanced AgeIsabelle Brunette,1 Juan M. Bueno,2 Mireille Parent,1,3 Habib Hamam,3 and Pierre Simonet3
2.12 Typical Values for Wave Aberration
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40 microns0.2 deg
Localizing the Receptive Fieldthe black spot indicates where a dim red laser has been turned on
Sincich et al, Nature Neuroscience, 2009
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Summary
• geometrical optics• physical optics• optical quality in the eye• metrics for determining visual image quality• measurement of optical quality in the eye
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Thank YouTHANKS FOR YOUR ATTENTION!