OptiMass 9500ICP-oTOFMSOrthogonal Time-Of-Flight The World’s Fastest BenchtopICP Mass Spectrometer

GBC has alwaysplaced a strongemphasis on qualityin all aspects of our operation,from design and manufacture tothe provision of service andsupport to our customers, andwe are fully committed tocontinuous evaluation andimprovement in all areas.

The GBC Quality ManagementSystem has been accredited tothe ISO 9001 quality standardby Lloyd’s Register QualityAssurance Limited. Thiscertification is your assurancethat the procedures andprocesses used to produce thegoods and services which GBCprovides comply with therelevant International Standard,and demonstrates commitmentto meeting the needs andexpectations of our customers.

For almost 30 years GBC hasbeen at the forefront of scientifictechnological development,manufacturing and marketing awide range of award winning,quality scientific instruments.

GBC’s product lines...

GBC Scientific Equipment

aawill advance people’s knowledge and

their capacity to enhance the quality of life

for all humankind.

HPLC ICP-OESAAS ICP-oTOFMS Rheometry UV-Vis XRD

“Sensitive Technologyfor a Sensitive World”

ISO 9001QualityAccreditation

Look into the elements of the new OptiMass 9500 ...

The 2nd Generation OptiMass 9500 packed withlots of great features to giveyou the technological edge!

3

With the release of the secondgeneration OptiMass 9500, GBCremains at the forefront in thedevelopment and marketing of ICPorthogonal Time of Flight MassSpectrometry.

The OptiMass 9500 has animpressive install base whichcovers both the traditional routinescreening and sample analysisthrough to unique laser ablation,graphite furnace and HPLCinterface applications. In fact, theOptiMass 9500 speed of analysisis particularly suited to any fasttransient type analysis.

No matter what yourapplication, the OptiMass 9500will analyse faster, moreaccurately and more costeffectively than ever before!

The OptiMass 9500 acquires allmasses simultaneously, analysistime is the same for one massor all masses.

The OptiMass 9500 performs30,000 acquisitions each second.Each acquisition simultaneouslymeasures every mass and isotopefrom mass 1 to mass 260 amu.This unique feature represents amajor advancement in technologyand differentiates the OptiMass9500 from any other ICP MassSpectrometer.

Low Operating Cost

Whether running a commerciallaboratory or a research facility,cost of operation is ALWAYSimportant. The OptiMass 9500 isboth faster and consumes lessArgon compared to a Quadrupole.When running USEPA method200.8 a quadrupole requires 180seconds per suite of elements. TheOptiMass 9500, however, requiresonly 25 seconds to analyse allelements.

Lower Argon Consumption

Due to the speed of analysis, the2nd generation OptiMass 9500requires less operating time thancompeting ICP-MS instrumentation,resulting in a 40% decrease inArgon consumption translating tocost savings.

Futuristic Technology

Simultaneous determination of trace elements inRiver Water using ICP-oTOFMS and USEPA 200.8method

Results were generated for allICP-MS measurable elementsand isotopes in the periodictable for this sample. With theOptiMass 9500, the sameanalysis time is required,regardless of the number ofelements required to beanalysed.

The USEPA 200.8 method hasbeen the standard method forICP-MS for the determination ofwaters and waste waters formany years.

Traditionally, this methodrequires 180 seconds acquisition timeper sample for the 20 elements to beanalysed. The OptiMass 9500 canaccurately quantify all ICP-MSmeasurable elements in 25 seconds.

SAMPLE COLLECTION

A SLRS-4 River Water Reference Material for trace elements wasanalysed.

STANDARD PREPARATION

A series of four standards containingall the elements of interest wereprepared. These were prepared in1%HNO33.

RESULTS

The following tables show the resultsfor the USEPA 200.8 elements. Thesecond table shows the results forother elements certified but notrequired for the USEPA 200.8 method.As can be seen in both tables, theresults obtained for the analysis showexcellent correlation with the certifiedresults.

Precise Environmental Analysis4

Elements Certified Result(ppb)

Result(ppb)

Al 54+ 4 52.0

Sb 0.23 + 0.04 0.24

As 0.68 + 0.06 0.690

Ba 12.2 + 0.6 12.60

Be 0.007 + 0.002 0.006

Cd 0.012 + 0.002 0.012

Cr 0.33 + 0.02 0.343

Co 0.033 + 0.006 0.029

Cu 1.81 + 0.08 1.730

Pb 0.086 + 0.007 0.093

Mn 3.37 + 0.18 3.440

Mo 0.21 + 0.02 0.190

Ni 0.67 + 0.08 0.69

Se n/a 0.23

Ag n/a 0.13

TI n/a 0.14

Th n/a 0.19

U 0.05 + 0.003 0.049

V 0.32 + 0.03 0.330

Zn 0.93 + 0.10 0.98

Results obtained for the USEPA 200.8required elements. n/a - no certifiedvalues available

Elements Certified Result(ppm)

Result (ppm)

Ca 6.2 + 0.2 6.13

Mg 1.6 + 0.1 1.57

K 0.68 + 0.02 0.67

Na 2.4 + 0.2 2.33

Fe 103 + 5 104.22

Sr 26.3 + 3.2 26.340

5

Rapid Sample Throughput

One of the largest Europeananalytical laboratories commissionedGBC to conduct a feasibility study todemonstrate how the Optimass 9500would benefit their analyticalenvironment. This laboratory analyzesmore than 2 million samples peryear, generating revenue in excess ofUSD$50M. With more than 700employees the laboratory isresponsible for the safe drinkingwater of 8 million Europeans.

The OptiMass 9500 wassuccessfully used for the analysis ofwater samples per the USEPA200.8 method. 26 elements in acertified river water sample werequantified. In contrast to aquadrupole ICP-MS, which requiresan 180 second acquisition time for20 elements per sample, theOptimass 9500 requires only 25seconds per sample.

5 Times Faster Sample Analysis than a QuadrupoleDuring this acquisition, it is possibleto analyze and quantify all ICP-MSmeasurable elements and isotopesbecause of the true simultaneousnature of the Optimass 9500’sdata acquisition capabilities.

All masses are displayedsimultaneously. This means thatthe user can view possiblecontaminants and elements notpreviously considered.

The objective of the laboratorywas to increase samplethroughput beyond thecapabilities of their existingquadrupole ICP-MS. Detectionlimits in the ppb range, rapidservice response, minimalmaintenance and maximummean time between failures wereall critical considerations for thislaboratory.

The OptiMass 9500 clearlydemonstrated that it could not onlymeet, but exceed, this customer’sstringent requirements and alsodemonstrated that it is a valuableanalytical instrument which canincrease sample throughput by afactor of five.

Results show excellent reproducability over 14 hours.

The additional information canprompt the user to investigate andquantify these newly identifiedcontaminants and elements.

Programmable

Simple, Powerful and Intuitive:The OptiMass 9500 Software

6

Easy to Use

The OptiMass 9500 software isthe most powerful and versatileavailable. Its functionality,programmability and ease ofuse, in addition to its diagnosticcapabilities, lead the industry inexcellence.

The Optimass 9500 generates avast quantity of information,which is easily managed andmanipulated by the anlaystthrough simple interfaces,recognizable icons, and easy toedit menus. The notebook styleformat keeps all parameters in alogical layout for ease of use.

As shown above, elements and/orall isotopes are easily selectedfrom the periodic table. Themultielement simultaneous natureof the OptiMass 9500 allowsdirect correction of interferenceswith no further analysis timerequired. Interference equationscan be easily entered into theanlalyte list. The OptiMass 9500can be easily calibrated on amass basis and Smartgate canalso be calibrated simply andautomatically.

The software incorporates easy touse automated acquisition

functions including automatic tuning,setting of all ICP parameters, methoddevelopment through to qualitativeand quantitative analysis and resultsgeneration.

With the click of a button, allinstrumentation parameters can be easily controlled.

As the OptiMass 9500 is trulysimultaneous across the entiremass range, calibration graphsand results can be created forone or all isotopes of a particularelement. This enables rapidmethod development asinterferences are immediatelyobvious when concentrationresults from different isotopes are compared.

Impressive Processing Power7

New Software Features

The OptiMass 9500 softwarenow includes new features toenhance productivity makingit easier to use. Theseinclude Auto Optimisation,Fingerprinting, Semi-Quantitative, Retrospective-Semi-Quantitative analysisand Scan overlays.

Diagnostics

All instrument parameters can be user selected to create acustomisable status panel.Status panels can be saved andaccessed anytime by a simpleclick of an icon. In addition,many service parameters areavailable for remote onlinediagnostics.

The complete spectrum data is saved for every replicatereading. This enables the userto retrospectively analyseelements that were notpreviously considered.

Element Identification

The advanced library query andsearch feature provides access tothe information needed for massidentification and for theinterpretation of spectra inunknown samples. The peakmass, resolution, and isotopicabundance can be simplyrecalled.

Just click andzoom forEasy ElementIdentification

Natural Abundance

Data

8

Unique Retrospective Semi-Quantitative Analysis

The ICP-oTOFMS offers the uniquefeature of powerful retrospectivesemi-quantitative analysis modenot available on any other form ofICP-MS.

The ICP-oTOFMS Semi-Quantitativeanalysis uses factory defined relativesensitivity factors (RSF) to define thedetector response to an unknownconcentration of analytes. Thesimultaneous nature of the OptiMass9500 allows not only semi-quantitative,but also retrospective semi-quantitativeanalysis (RSQ).

Every analysis contains data for everymass, the OptiMass 9500 continuouslyacquires data from mass 1 through tomass 260 amu. Utilizing the RSQfeature, this data is always available forfuture examination and quantification formasses not previously callibrated.

Data for Future Reference

When comparative studies arerequired, such as in ForensicScience, it can be very useful to usespectral fingerprinting.

This type of analysis allows spectrato be compared to determine howclosely they match by giving afigure from 0 to 1. Thiscomparison is achieved using astatistical algorithm that compares atest spectrum to a known spectrum.

This can be a comparison of anSRM to sample material or thecomparison of scene-of-crimeevidence to samples recovered fromsuspect’s residence, vehicle orpersonal belongings.

The OptiMass 9500 then providesrapid multielement analysisenabling complete spectral datacollection. This, coupled with thepowerful statistical fingerprintingsoftware of the OptiMass 9500,completes the package forcomparative analysis.

SMALL VOLUMES

The true simultaneous multielementcapability of the Time-of-Flighttechnology used in the OptiMass9500 ensures that all informationcan be obtained from the analysisof small volume samples oftenfound in scene-of-crime scenarios.

For example, in the event of thedetonation of so called, “dirty”weapons, the speed andportablility of the OptiMass 9500make it ideal for “on site”fingerprinting of radio-nuclidesreleased during the event.

Spectral fingerprinting is also anextremely useful tool in screeningsamples for many applications. Theuse of this technique, coupled withthe speed of time-of-flight, is anideal tool for rapid screening ofsamples for international securitypurposes.

9

Sample Matching

This would allow authorities to quickly implement thecorrect safety procedures.

Multielement Spectral Fingerprinting Capability

The Time-of-Flight technology usedin the OptiMass 9500 allows rapidauto-optimisation of all instrumentparameters across the entire massrange. The simultaneous acquisitionof all masses from mass 1 to mass260 amu means that this feature willautomatically compensate for massbias effects. The flexible OptiMass9500 software allows the use of anycombinations of instrumentparameters to perform theoptimisation.

The auto optimisation software willoptimise torch position, nebuliserflow, beam energy and otherfocusing parameters. Also, anyisotope mass can be selected foroptimisation on either sensitivity orresolution. Minimum and maximumparameter values can be defined aswell as parameter step size duringoptimisation, to allow for settling ofgas flow parameters. Thecomprehensive results panel suppliesa complete report of the entireoptimisation process (if required).

10

Auto-Optimisation

Simple, Automated and Fast

Laser AblationICP-oTOFMS

The Laser Ablation Sampling

GBC now offers a packagedLaser Ablation-ICP-MS system.The integrated Dual Screensoftware control system facilitateseasy viewing and control of boththe Laser Ablation and Optimass9500 software.

This provides a flexible userfriendly option for the rapidmultielement analysis of solidsamples.

The OptiMass 9500 can acquiredata at a rate of 30,000 full massspectra per second.

The fast data acquisitiontranslates not only to faster speedof analysis but the quality of thedata produced is significantlyimproved.

Transient Analysis11

Dual screens for easy viewing

The OptiMass 9500offers 6 times greaterstability than a standardQuadrupole.

Specifications

Description

Benchtop Inductively CoupledPlasma orthogonal accelerationTime-of-Flight Mass Spectrometer(ICP-oTOFMS), controlled by anexternal computer using Windows®based software.

RF Generator

Solid state 27.12 MHz generator • Computer controlled from 500 W to 1500 W with auto tuning • Auto-start from software.

Sample Introduction

Nebuliser and Spray ChamberConcentric glass nebuliser with thermostatted glass jacketed spraychamber.

Torch

Low flow, low power, single piecequartz torch.

Torch Adjustment

Computer control of torchmovement in the (x-y-z) planes to0.1 nm resolution for optimalanalytical positioning relative to theion sampler interface.

Argon Flows

Individual gas flows undercomputer control

• Mass flow regulation on all gaslines.• <12 L/min total argon flowtypical.

Peristaltic Pump

Computer controlled four-channel12-roller pump, speed 0-60 rpm • Auto fast pump setting for rapidwashout.

Interface and Ion Optics

Easily removable three conesystem

• Water cooled interface. • Cone access via motorisedretraction of the torch. • Gate valve vacuum seal.

Clean Vacuum System

Conventional three-cone interfacevacuum system with differentialpumping utilising low maintenanceturbomolecular pumps and rotaryvane backing pump.

• Automatic sequencing andcontrol. • Interlocks to prevent damage topumping system and high voltageelements in the event of a plasmaextinction.

• Turbomolecular pumpsprotected from overloadconditions.

Optional Kleenvac oil-free rotarypump allows extended detectorlife due to lower hydrocarboncomponents in the vacuumsystem.

Mass Analyser and DetectorSystem

Orthogonal acceleration Time-of-Flight mass spectrometer • Mass range 1 to 260 amu. • More than 30,000 full spectraper second ion extraction speed. • Parts per trillion detection limits.

Automatic detector protection anduser-selectable matrix ionselimination with SMARTGATE ionblanker.

• Up to 1 GHz detection systemsampling rate. • Unique detection system withdiscrete dynode multiplier forextended dynamic range. • Transient signal acquisition rateof 100 integrated full massspectra per second.

The resolution of the OptiMass9500 is typically 2000 or greaterfor U238 or 0.4 amu.

Parts per Trillion Detection Limits12

GBC OptiMass 9500Spares & Accessories

Precision glassware readily available

Precision Components

The precision designed andengineered components andconsumables (as shown on the left)are manufactured to very rigidspecifications. Designed withdurability and longevity in mind, theoperator can still replace parts andconsumables quickly when requiredto ensure any downtime is minimised.

SDS 540 Autosampler

The new 40% faster GBC automatedSample Delivery System, SDS 540,offers automation when combinedwith your OptiMass 9500 ICP-oTOFMS. The SDS 540 is totallycontrolled by the OptiMass 9500software, providing random accessas well as micro sampling capabilityfor small samples and transientanalysis.

The SDS 540 allows varioussampling procedures and automationfor liquid samples. It is capable ofhandling up to 540 samples and sixdifferent rack types in variousconfigurations. The OptiMass 9500combined with the SDS 540 meanslaboratories can quickly performtrace analysis to ppt levels withouttime consuming and costly sampledilutions.

Such extensive, unattended operationleads to high cost effectiveness and isespecially beneficial to environmentaland quality control laboratories.

HG3000PII Hydride Generator

The GBC Hydride Generatorenables the analysis of the hydrideforming elements using a vapourgeneration technique. Elementssuch as As, Bi, Sn, Sb, Te, Se andHg can be determined with partsper trillion detection limits.

The HG3000PII hydride generatorincorporates precision glasswarefor highly efficient mixing ofreactants and gas liquid separationto ensure reproducibility and highsensitivity.

Precision Components13

The HG3000PII hydride generator

The OptiMass 9500 three-cone interface

SDS 540 Autosampler

SoftwareTrue multi-ttasking Windows® basedoperating software.

• Modular design with Method,

Samples, Analysis, Instrument Control

and Results modules accessible from any

part of the software.

• External and isotope dilution

calibration.

• Automatic correction for interferences

and measurement with internal

standards.

• Measurement of transient signals.

• Isotope ratio measurement.

• Complete quality control protocols,

including check samples, spike

recoveries, calibration failure and QC

limits.

• Unlimited number of samples in a run.

• Comprehensive report generation.

• Complete computer control of instrument

parameters.

• Auto-optimisation of plasma parameters

and auto-tuning of mass analyser.

• Customisable instrument status display.

• Fingerprinting

• Auto-optimisation

• Semi-Quantitative analysis

• Retrospective Semi-Quantitative analysis

• Access data base

• Complete full spectrum results data

saved for every replicate

Ease of Use14

Customer Service

You can be assured that GBC willprovide you the service that yourequire. With more than 100agents across the globe atechnician will never be far away.

GBC Customer Serviceincludes:

Rapid Service Response

GBC has many factory trainedservice representatives world-wideso you can be assured of a rapidresponse to your servicerequirements.

Rapid Service Response15

Personalised InstrumentInstallation and Training

An experienced product specialistfrom the GBC globalheadquarters will travel to yourlaboratory site to performinstallation, qualification andtraining.

Remote Diagnostics

Easy to install, user friendlysoftware enables GBC toprovide you with complete on-line remote instrumentdiagnostics and troubleshooting.

Designed and manufactured byGBC Scientific Equipment Pty LtdA.C.N. 005 472 686

GBC reserves the right tochange specifications withoutprior notice.

GBC publication number01-0875-03July 2006 Australia

GBC SCIENTIFIC EQUIPMENT

Manufacturer of world-classscientific instruments andaccessories :AAS, HPLC, ICP-OES, ICP-oTOFMS, Rheometry,UV-Vis and XRD

12 Monterey RoadDandenong, Victoria 3175Australia

Telephone 61 3 9213 3666Facsimile 61 3 9213 3677email gbc@gbcsci.comURL www.gbcsci.com

All trade-marks and trade-namesare the property of theirrespective owners.

OptiMass 9500 SPECIFICATIONS

OptiMass 9500 Dimensions1200 x 840 x 700 (W x D x H, mm)

OptiMass 9500 WeightsPacked - 390 KgUnpacked - 270 Kg

Electrical Requirements200-240 V AC, 7 kVA, 20A. 50/60 Hz

ORDERING INFORMATIONGBC OptiMass 9500 ICP orthogonal Time-Of-Flight Mass SpectrometerPart No. 99-2155-01