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Page 3 Page 3Our human clinical trials summarised

Page 2Bio-Kult student bursary winner revealed

Protexin Veterinary’s winning digestive health drive

www.protexin.comIssue 13 | July 2015

Celebrating 23 years of good health

Probiotics International Ltd (Protexin) introduced their first probiotic product on the market over 22 years ago. Back then the term ‘probiotic’ was not as well-known as it is today, but as the evidence of probiotic benefits grew, so did the knowledge and the number of products on the market. This evidence is still growing at a rapid rate, and as an example, a simple PubMed search for published trials using the search word ‘probiotic’ brings over 12,700 articles, whereas a similar search just 5 years ago returned less than half this number.

About Protexin

Protexin products are sold to over 80 countries worldwide and manufacturing is at their purpose built facility in Somerset, South-West England. Quality is of paramount importance, with a dedicated quality department and accreditations including cGMP (audited by the MHRA) and ISO 9001:2008.

The Protexin Strains

All of the Protexin strains are lodged at a leading culture collection bank known as the National Collection of Industrial, food & Marine Bacteria (NCIMB). This allows safe storage as well as a library to ensure no genetic shift of the strains.

This is important as there are many different strains of the same species, but as research has shown, their efficacy

and mode of action can vary. Therefore, preventing genetic shift will mean that the benefits of the Protexin strains will not change. It is for this reason that when taking a probiotic, it is essential that it is identified to strain level, produced to the highest quality, and backed by good science.

Protexin’s Research

One of the key areas of investment for Protexin is research. A large, diverse programme is in place across all divisions, covering new product development, as well as new clinical evidence for existing products.

Janine Barlow, Technical & Product Development Manager at Protexin explains the process; ‘At Protexin, we have a philosophy of producing innovative, research-based products to the highest standards for both human and animals. Our product development can take a long time, and once a new product is launched into the market, the research does not stop there. We are committed to an extensive research programme that includes supporting products already on the market as well as developing new products. For example, on the healthcare side, we are commissioning four new clinical trials on existing products over the next 12 months, and this is in addition to more than 15 clinical trials already completed with Protexin products.’

ourtop

stories

An Introduction to Protexin Research

researchspecial

CONTINUED ON PAGE 2

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AdultsProtexin

probiotics significantly

improved liver function in patients with

Non-alcoholic Fatty Liver Disease

2014

Protexin probiotics

significantly reduced fasting blood sugar

levels in patients being treated for Metabolic

Syndrome

2014

Protexin probiotics

significantly improved liver

function in patients with Non-alcoholic

Steatohepatitis

2013

Protexin probiotics

significantly reduced abdominal

cramps and constipation

2011

Protexin probiotics significantly

reduced Bacterial Vaginosis

2014

Human Clinical TrialsOur Protexin Strains

Children

Protexin probiotics

significantly reduced diarrhoea associated

with antibiotics in children

2013

Protexin probiotics

significantly reduced sepsis and hospital stay in babies with

Neonatal Pneumonia

2012

Protexin probiotics significantly

reduced childhood constipation

2010 & 2014

Protexin probiotics

significantly improved recovery

in infants suffering with

Acute Diarrhoea

2010

Protexin probiotics

significantly reduced symptoms

of eczema in children

2011

Protexin probiotics

significantly decreased intestinal

inflammation in children with Cystic

Fibrosis

2013

Protexin probiotics

significantly reduced

infant colic

2014

Protexin probiotics significantly

increased H. pylori eradication rates in

children

2013

Here is a summary of some of the latest human

clinical trials using the Protexin strains. If you

would like to read a more detailed research

summary visit www.protexin.com/research.

Janine continues, ‘our commitment to new product development research is large too, with projects both on the human and veterinary side that will keep us at the forefront of producing innovative, research-based new products.’

The product development at Protexin includes more than just clinical trials – pre-clinical work such as proof of concept, survivability and shelf life stability are to name just a few stages of this process.

The Research Team

With more than 100 people employed across the company, our knowledgeable and committed research and product development team has grown in all divisions. On the healthcare side is Head of Research Peter Cartwright, who has a wealth of microbiota knowledge, Medical Advisor Dr Mayur R Joshi and Technical Advisor Natalie Lamb. On the Veterinary side, there is Veterinary Technical Manager, James Kyffin and Veterinary Research Manager, Lindsay Rose. Lindsay explains ‘the depth of research here at Protexin is paramount to producing products that optimise animal health. It is an exciting time with new research results being released this year and more trials currently under way.’

Protexin works with various leading organisations across the world on research projects, including universities, clinical research organisations and hospitals. Janine explains ‘it is the variety of organisations that we have links with and our in-house knowledge which enables us to produce high standard research on scientific formulas alongside world-leading experts’.

Summary

When you buy a Protexin product, you can be assured it is of the highest quality, backed by effective science and supported by a highly qualified team of experts. We look forward to sharing new developments in the future!

CONTINUED FROM PAGE 1

Members of our Healthcare Research Team - Peter, Janine and Mayur

VeterinaryProtexin are winners!

We’re delighted to announce that we have been awarded the SME Marketing Campaign Award at the 2015 Veterinary Marketing Awards!

Awarded for the Digestive Health Drive which ran last summer, the aim of this campaign was to educate pet owners on digestive health issues in dogs and provide support to veterinary practices.

Focusing on Pro-Kolin+ and Pro-Kolin Enterogenic, the campaign incorporated new creative, a dedicated website (www.pro-kolin.com), informative animations and educational material for veterinary practices to use.

Other Vet News:

Urinary Health Campaign. We recently focussed on our dog and cat products, CystoPro and Cystophan, which offer high level support for urinary health. We launched an informative website, www.urinaryhealth.co.uk and we also have a range of educational material for veterinary practices to make use of.

Collecting our award!

ourprobiotic

news www.protexin.comIssue 13 | July 2015

Don’t forget to like our Facebook pages and follow us on Twitter to keep up to speed with all the latest news and events

Human health careBio-Kult Student Bursary Winner Announced!

Stephanie, a student studying MSc Nutritional Therapy at Worcester University has won £1000 towards her career goals. Kristin, a student at CNM came second and has won herself £500. Thank you to everyone who took part.

Natural Products Europe 2015

We had a great time at Natural Products Europe 2015. Here is a picture of our health store inspired Bio-Kult stand and informative ‘loo taboo’ Lepicol stand.

AgricultureWe attended the International Pig and Poultry Show held in Nagoya, Japan

Whilst attending the event, Agriculture Sales Manager, John Tuer gave a paper setting out the role of Protexin Concentrate to reduce the effects of gut diseases including PEDv in piglets.

Equine PremiumPampered Ponies!

We received great feedback and over 80 entries for our Pampered Ponies Facebook competition. Congratulations to Amanda Prior,

whose photo of her horse Strider reading the paper gained 1914 ‘likes’, winning her a £300 spa voucher, a pamper grooming kit for her horse and a stack of Equine Premium goodies!

Bursary Award

We are now accepting entries for this year’s Protexin Equine Premium bursary award! Head over to www.equinepremium.com/bursary now to be in with a chance to win. This year, we will be offering one fabulous rider a whopping £600 Bursary, plus a deserving under 18 the chance to receive a £200 Bursary. Hurry! Entries close 31st July.

morenews

The Bio-Kult team at

CAM ConferenceGut Balancer fan Bimbo,

the 53 yr old Shetland

Ingredients:1 cup pecans

1 cup dates

4 tablespoons of unsweetened desiccated coconut

5 tablespoons raw cacao

Pinch of salt

2 tablespoons agave/raw honey or maple syrup

ourprobiotic

news www.protexin.comIssue 13 | July 2015

Raw Brownies! Protexin’s Charlotte has been making raw brownies and they’ve gone down very well at Protexin HQ! Here’s the recipe - let us know if you decide to make them too!

Process:1. Process 1 cup of pecans in a food

processor.

2. Add 1 cup of dates and process

again – the mixture should be able

to stick together when pinched.

3. Add remaining ingredients and

process until mixed thoroughly.

4. Press into a square tin, lined with

parchment paper and place in the

fridge for 2 hours until firm.

5. Cut into bite sized pieces and

enjoy. Best served straight

from the fridge.

Following us on social media is a great way to keep up to date with all our latest news, events and research.

Probiotics International Limited (Protexin). Lopen Head, Somerset, TA13 5JH, United Kingdom. Telephone +44 (0) 1460 243230 Fax +44 (0) 1460 249543 info@protexin.com www.protexin.com Protexin, Bio-Kult, Equine Premium and Lepicol are registered trademarks of Probiotics International Limited (Protexin). All rights reserved.

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Bio-Kult www.bio-kult.comfacebook.com/biokultprobiotics@Bio_Kult

Lepicol www.lepicol.comfacebook.com/lepicol@Lepicol_UK

Protexin Veterinary www.protexinvet.comfacebook.com/protexinveterinary@Protexin_Vet

Protexin Equine Premium www.equinepremium.comfacebook.com/protexinequinepremium@ProtexinEquine

Clare at Wild Oats health store

Dan and Maggie at the Vets Now Brighton Conference Natalie at the NNA Conference

Sarah and Dan at The Vet Group Partner Conference

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