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Page 1: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

published by in association with

w w w . s p e c c h e m o n l i n e . c o m

OutsourcingSpecial Publication

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Page 2: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

ContentsAn introduction from the editor 3

AMI 4

CU Chemie Uetikon GmbH 5

Dishman Europe Ltd. 5

Dottikon Exclusive Syntheis AG 6

Dystar 6

Gee Lawson Limited 7

Genzyme Pharmaceuticals 7

Jai Research Foundation 8

NOTOX B.V. 8

Neogen Chemicals Limited 10

Omnichem 12

ORGANICA Feinchemie GmbH 12

PPC - Potasse et Produits Chimiques SAS 13

Sajjan India Limited 13

Schirm GmbH 14

St Andrews ChemTech International Limited 14

Saltigo GmbH 15

Tokyo Chemical Industry Co., Ltd. 16

Valsynthése Ltd 16

WelyChem 17

Expertise matrix 18

Company contact details 19 & Back cover

Specchem magazine Outsourcing special publication page 2|

Published with the July/August 2008 issue of

Speciality Chemicals MagazineDMG World Media Westgate House, 120/130 Station Road, Redhill, Surrey RH1 1ET, UK

Tel: +44 (0) 1737 768611 Fax: +44 (0) 1737 855418

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Page 3: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

Introduction from the EditorWelcome to this year’s Outsourcing Special Publication from SpecialityChemicals Magazine.

‘Outsourcing’ has become something a scare word in recent years. In the UK at least, itis increasingly seen in terms of big consumer-oriented firms moving their call centres toIndia; on a wider scale, it is taken to mean factories closing in the US or Europe to re-open next week in Mexico or China.

In reality, outsourcing is a fact of life. It always has been, albeit that it has picked uppace in the last generation. In the media, where I work, there was a time when everypublisher printed their own magazines; it was a core capability. Virtually none do now.Outsourcing means simply taking the decision to pay a third party to do what you could- at least at the outset - do yourself because it makes sense to do so. Outsourcing ispretty much the history of civilisation in microcosm.

In the fine and speciality chemicals sector, companies compete with each other for theoutsourced manufacturing business of third parties but they have also been outsourcingcertain reactions to each other for years. It is hard to imagine Chemspec and SpecialityChemicals Magazine coming into being if they did not.

All this may sound obvious, but it is well to remember that outsourcing is neither a one-way street nor a novelty. And the above definition of what it means reminds us that thecompanies who offer contract manufacturing services are competing as often as not withspare capacity at the customers’ own sites.

This is a hard competition to win. Having invested in capacity, companies naturallyincline to using it. To win the order, CMOs must offer real added value that makes theiroffer more attractive than those from other CMOs, more viable than the alternativechemical and/or biological routes and a better all-round bet than the low-costalternatives from China and India.

All of the companies featured in this special publication have banked their futures onbeing a top ranking player in the field, either in terms of size, breadth of capabilities,special expertise or value-added service. They realise that there is no future in being ageneric supplier of low-value products any more and have invested in an extraordinarilywide array of technologies and competencies on offer. We invite you to take a look andsee what they can do for you.

Dr Andrew Warmington Editor - Speciality Chemicals Magazine

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Page 5: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

CU Chemie Uetikon GmbH:We offer a broad expertise toour pharmaceutical andbiotechnology partners: customsyntheses of advanced interme-diates and APIs, orphan drugsand speciality chemicals are ourcore competencies.

We offer a high level of qualitycompliance (cGMP), a 20 year his-tory of successful FDA inspectionsand state-of-the-art production facil-ities.

The Lahr facility has a total reactorvolume of 100 m3 and approvalfor 34 different chemical reactiontypes. We produce intermediatesand APIs for the generic and inno-vator pharmaceutical industries.Furthermore, we offer more than250 advanced intermediates in ourgeneral catalogue. Beside ourestablished products, we also per-form custom synthesis

We are operating a state-of-the-artGMP plant which includes a 1,000l reaction train (train = reactor, crys-talliser, centrifuge and dryer), 2x3,000 l trains and a 6,000 l train.All these trains operating independ-ently from each other and arearranged vertically and fully encap-sulated. Just recently we haveexpanded our capabilities with theinstallation of a low temperaturereactor which is part of a 3,000 lreaction train (2,500 l; down to -80°C, 25 bar).

CU Chemie Uetikon GmbH hasdeveloped specific expertise in theareas of hydrogenation, high pres-sure reactions and Grignard reac-tions. We have special experiencein protected amino acids and chiralcompounds. We develop multi-stepsyntheses and can offer the fullscale of auxiliary services, like ana-lytical method development andthe elaboration of DMFs.

Our expertise is your success.

PRINCIPAL CONTACTDr. Hendrik Baumann, Commercial Director

CU Chemie Uetikon GmbH

Raiffeisenstrasse 4,77933 Lahr, Germany

Tel: +49 7821 585 0 Fax: +49 7821 585 230

Email: [email protected]

Website: www.uetikon.com

Specchem magazine Outsourcing special publication page 5|

CU ChemieUetikon GmbH

DishmanDishman: an India- and UK-based global provider ofcontract R&D, custommanufacture for pharmaceuticaland fine chemicals.

Headquartered in Ahmedabad,Gujarat, India, Dishman started as aPTC producer and later applied thisexperience to the manufacture ofintermediates and APIs. Now it is amajor supplier of quaternaryammonium & phosphonium saltsand is Asia’s leading contract R&Dand custom manufacture providerto multinational chemical andpharmaceutical companies.

Dishman provides processdevelopment, API route optimisationand kilo synthesis. It services clientsin Europe and America via Londonand New Jersey offices, with localtechnical/commercial support inGermany, Italy, the Netherlands andFrance.

Technology and intermediates areavailable for the following APIs:Alizapride, Butethamate, Cisapride,Cisatracurium besylate,Ethylphenacemide, Glibenclamide,Lansoprazole, Levomepromazine,Loratadine, Losartan, Omeprazole,Pantoprazole, Perimetazine,Rabeprazole and Venlafaxine.

PRINCIPAL CONTACT

Christian Dowdeswell

Dishman Europe Ltd.

120 New Cavendish Street

London W1W 6XX, UK

Tel: +44 (0)20 7323 0608

Fax: +44 (0)20 7323 0609

Email: [email protected]

Website: www.dishman-europe.com

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DyStar

DyStar is your first choice ascompetent partner for tailor-made products, with a longtrack record in the productionof agricultural, pharmaceutical,cosmetic, fine and specialitychemicals.

We are a single-source supplier ofunique solutions for a wide varietyof problems involving the manufac-ture of advanced intermediates.

Our services cover the entireprocess chain from lab and pilot tri-als to bulk production. Our experi-enced chemists can help you toachieve optimum manufacturingconditions and make sure yourproducts meet all necessary specifi-cations.

We are committed to ResponsibleCare and our plants in Europe,South America and Asia operate totop ecological standards.We have a strong background inthe production of textile dyes andthe legal permits required to han-dle all types of chemicals, interme-diates and solvents.

Our reaction vessels range from 1m3

to 60m3, enabling us to manufacturedifferent batch sizes economically.

We offer a rapid response to helpyou cut the time to market andbenefit from new business opportu-nities as soon as possible.

Our aim is to be your partner, nota competitor.

PRINCIPAL CONTACT

Dirk De Vos

DyStar Texilfarben GmbH & Co. Deutschland KG

65926 Frankfurt, Germany

Tel: +49 (0) 69 2109 2288

Email: [email protected]

Website: www.dystar.com

Chemical solutions you can trust

DottikonExclusiveSynthesis AG

PRINCIPAL CONTACT

Gabriela Schuppli

Dottikon Exclusive Synthesis AG

Hembrunnstrasse 17

5605 Dottikon

Switzerland

Tel +41 56 616 81 11

Fax +41 56 616 81 20

Email: [email protected]

Website: www.dottikon.com

Your Specialist for Hazardous Reactions.

DOTTIKON EXCLUSIVE SYN-THESIS is an SWX-listed Swisscustom manufacturer withalmost 100 years of experiencein hazardous reactions. At theproduction site in Dottikon,APIs, preformulated drugs andhigh quality intermediates aremanufactured for the leadingpharmaceutical and chemicalcompanies. DOTTIKON ES isspecialised in robust and effi-cient process development forrapid scale-up, either in batchor continuous mode. Large-scale syntheses of up to 15steps have been performed,including strongly exothermic

reactions and highly reactive,unstable or highly potent com-pounds.

Currently, DOTTIKON ES is in theprocess of expanding one of itsmulti-purpose production plants byadding six new reactors (18 m

3in

total), including a new 1600 lHastelloy reactor for processes per-formed at temperatures as low as -100°C. Further, a new contain-ment system was installed in oneof the pilot plants, allowing for thehandling and production of Class-IV HAPIs (OEL = 1 - 20 µg/m

3) in

1,200- and 750 l stainless steel andglass-lined reactors, respectively.

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Gee Lawson An Integrated Resource of Custom Manufacturing

Founded in 1939, GeeLawson was established tosupply a range of finechemicals, dyes, stains andindicators for research andindustry worldwide.

Sourced Serviced SatisfiedGee Lawson's traditional businessis the sourcing of semi-bulkquantities of speciality chemicals.Our computerised database, whichis constantly updated, allows us toidentify supply sources quickly andoffer a broad range ofcompetitively priced products.

Through our extensive worldwidesupply network, our SpecialistTeam works with our customers tosolve supply issues across a widerange of methodologies includingto date:

• Esterification

• Addition

• Elimination

• Reduction

• Oxidation

• Bromination

• Nitration

• Friedel-Crafts

• Diazotisation

• Formylation

Shipping and Packing ServicesWith the knowledge andexperience of our in-houseDangerous Goods Safety Advisor,we can help you to ship hazardousmaterial worldwide, safely, inaccordance with appropriateregulations.

Additionally, we can re-pack alltypes of air sensitive and hazardousmaterials to single use quantities,allowing customers to purchase insemi-bulk but with the convenienceof pre-pack.

PRINCIPAL CONTACTMike Norman

First Floor, Melville House

8-12 Woodhouse Road

London N12 0RG

UK

Tel: +44 (0)20 8343 5400

Fax: +44 (0)20 8445 7529

Email: [email protected]

Website: www.geelawson.co.uk

PRINCIPAL CONTACTGenzyme Pharmaceuticals

675 West Kendall Street

Cambridge, MA 02142 USA

Tel: :+1 800 868 8208 or +1 617 374 7248

Fax: +1 617 768 9765

Email: [email protected]

Website: www.genzymepharmaceuticals.com

"Taking the problems out of sourcing products"

Genzyme Pharmaceuticals, abusiness unit of GenzymeCorporation, provides over 25years of experience to pharma-ceutical and biotechnologycompanies in the area of cus-tom manufacturing of specialitychemicals and pharmaceuticalmaterials. From early R&Dphase through full commercial-isation, build your successaround our integrated resourceof highly trained people, state-of-the-art cGMP Swiss facilityand history of chemical excel-lence, with products includingcomplex custom-manufacturedchemicals, registered interme-diates, APIs, and drug deliverymaterials.

Our corporate infrastructure allowsfor the flexible autonomy of a dis-tinct business within the stability ofa premier biotechnology corpora-tion. We extend this unequaledvalue in custom manufacturing tocustomers through an integratedresource of:

Core competencies

• Speciality chemicals

• Amino acid derivatives &building blocks

• Peptide synthesis

• Synthetic phospholipids,sphingolipids, other lipids

• Polymers

• Carbohydrates

• Project management

Chemistry excellence

• Exceptional command offundamental chemistries

• R&D & kilo lab facilities tosupport early stage chemicaldevelopment

Manufacturing capabilities

• Production capacities from kiloto tonne quantities

• Equipment flexibility to suitdevelopment needs

• FDA inspected plant for APIs

Analytical and regulatory support

• GMP certificate

• Filing and maintenance of DMFs

• CMC quality documentation inCTD format

AN INTEGRATED RESOURCE OF CUSTOM MANUFACTURING

CORE COMPETENCIES

CHEMISTRY EXCELLENCE

MANUFACTURING EQUIPMENT

ANALYTICAL AND REGULATORY SUPPORT

CORPORATE INFRASTRUCTURE

PEOPLE

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Page 8: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

NOTOX was founded in 1983to provide full safety and toxi-cology services for the pharma,chemical and agro industries.Privately owned NOTOX con-tinued its organic growth strat-egy over the years.

In July 2005 NOTOX became partof a world wide group ofautonomous companies providingtoxicology research services. Thistrans-Atlantic presence was builtwith a vision to seamlessly addressthe service needs of internationalindustry partners.

We provide regulatory services forthe evaluation of existing chemicals(HPV and REACH). For REACH wehave developed a 10 stepprogramme to compliance. Fromthe inventarisation pre-registration,data evaluation including IUCLID5completion of robust summariesand hazard/exposure assessments(CSA/CSR) to dossier submissionand follow up. These services areprovided for companies andconsortia. We can also act as your

“only-representative”, third partyrepresentative or organizeSIEF/consortium meetings andactivities if needed. (e-mail:[email protected])

The facility in ‘s- Hertogenbosch islocated conveniently close to majorairports and employs now over 300staff. The latest major extension ofthe facility became operational inJuly 2008, allowing a 40% growth.The service profile consists of invitro and in vivo toxicology, kineticsand metabolism studies, geneticand environmental toxicology aswell as physical-chemical testing forpharmaceutical and (agro-)chemical industries. The toxicologyresearch is supported by anextensive (bio-) analytical laboratoryfacility with state of the artequipment, method validation andmetabolite identification.Operations have been endorsed bythe Dutch GLP-Inspectorate andare in accordance with theprinciples of OECD/EPA/FDA GoodLaboratory Practice.

PRINCIPAL CONTACTIng. Chris de Ries & Ir. Danny Haacke

NOTOX B.V.

P.O. Box 3476

5203 DL ‘s-Hertogen bosch

The Netherlands

Tel: + 31 73 640 6700 Fax: + 31 73 640 6799

E-mail: [email protected] & [email protected]

Website: www.notox.nl

Specchem magazine Outsourcing special publication page 8 |

NOTOX B.V.

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Contact the sales teamJohn LaneTel: +44 (0) 1737 855 [email protected]

Organised byIn association with Official media partnerIncorporating

www.chemspeceurope.com

200917 – 18 JUNE 2009GRAN VIA EXHIBITION CENTERBARCELONA, SPAIN

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Specchem magazine Outsourcing special publication page 12|

OmniChem offers a blendof high technology know-how, a level of quality thatmatches the demands andexpectations of today’spharmaceutical world,flexibility andtrustworthiness, basedupon personnel of thehighest competence, onadapted equipment andmulti-purpose facilities onthree different sites.

OmniChem has strong expertisein azide chemistry, catalytichydrogenation, hydride reduction ,organometallic chemistry,oxidation, phosgenation, nitration,low temperature (-100°C for whichit has the world’s largest capacity),high pressure, cycotoxic handlingand natural product extraction

OmniChem’s assets :

• worldwide marketing network

• broad technology base

• key technologies

• multi-purpose facilities

• total GMP capacity of 590 m3

• specific equipment

• Highly Potent Compoundsdevelopment and manufacturing.

• highly-skilled R&D support

• regulatory compliance

• GMP, FDA approval

• From gram to multi-tonnes.

Contact OmniChem for a detailedlist of core competencies.

OmniChem

PRINCIPAL CONTACT s.a. Ajinomoto Omnichem n.v

OmniChem Division

Industrial Research Park Fleming

B-1348 Louvain-la-Neuve, Belgium

Tel: +32 10 483111 Fax: +32 10 452553

Email: [email protected]

Website: www.omnichem.com

ORGANICAFeinchemie

The high demandsplaced on quality, strictcustomer orientation,outstanding reliabilityand a high level ofscience and technologyhave elevatedORGANICA from atraditional manufacturerof photographicchemicals to a valuableand recognised partnerfor CustomManufacturing ofpharmaceutical intermediates,functional dyes andagrochemicals.

Located in the ChemieParkBitterfeld-Wolfen, where it wasestablished in 1995, ORGANICAFeinchemie GmbH has focused onsyntheses of high quality andrefined organic specialties for avariety of industrial applications. Inits long pre-history the companygathered chemical experience in alot of laboratory and productionprocesses and is now able toperform 70 listed reaction types,which, today, makes it possible toact quickly and flexibly. Aparticularly strong expertise isenjoyed in the performance ofprocesses with specific hazardousreactants such as azide chemistry,alkylation, cyanation, halogenation,nitration and sulphonation, as wellas in heterocyclic syntheses andhigh pressure reactions.

The innovative and highly motivatedteam of chemists and researchersand their permanent endeavour forexcellent results, accompanied bythe Quality Assurance System and inconnection with the ISO 9001certification, has guaranteed therealisation of numerous customsynthesis projects and the successfullaunch of many new productsduring the last years.

With its own fully-equipped R&Dlaboratory as well as pilot plant andmultipurpose facilities with a totalreactor capacity of 100 m3, thecompany is flexible enough toperform custom synthesis and tollmanufacturing in a wide range,whereby the service covers thecomplete project cycle, fromprocess design through pilot scaleup to commercial production. Arecently FDA inspected GMP kilolab accomplishes the possibilities forproducing pharmaceutical productsand parenteralia.

PRINCIPAL CONTACT

Werner Salomon Marketing and Sales DirectorORGANICA Feinchemie GmbHKunstseidestr. 5D – 06766 Bitterfeld-WolfenGermanyTel: +49 3494 636389 Fax: +49 3494 637239Email: [email protected] Website: www.organica.de

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Page 13: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

A leading manufacturer ofspecialty chemicals, with itsmanufacturing site inAnkleshwar, India’s largestchemical zone, Sajjan is a 100%export-oriented unit, whosecustomers include majormultinational companies. Withits state-of-art, ISO-9001,certified facility in Ankleshwarand its new site in Dahej, aSpecial Economic Zone (SEZ),Sajjan will make an idealpartner for customers requiringproducts on a contractmanufacturing basis.

Sajjan also offers specialitychemicals which have applicationsin agrochemicals, pharmaceuticals,dyes, pigments & electronics.

The manufacturing site built on75,000 m2 of land, houses threeplants comprising a total reactorcapacity of 3,700 m3.

The core technology matrixincludes:• High Pressure Ammonolysis• Chlorosulphonation• Catalytic Hydrogenation• Heterocyclic Chemistry• Polychlorination

It is well-complemented by large-scale capacities for:• Acetylation• Friedel-Crafts• Nitration• Diazotization• Alkali Fusion

Expansion – Dahej SEZSajjan India has acquired 100,000m2 of land in India’s first chemicalSEZ. Sajjan will develop this site forthe manufacture of specialitychemicals on a contractmanufacturing basis.

The Dahej SEZ will have worldclass infrastructure & a largepetrochemical complex.

Dahej is only 50 km from theexisting site and also close toNhava Sheva & Mumbai ports.

The combination of technology &spare space will make Sajjan yourideal supplier, since our focus hasalways been on:

• Developing cutting-edgetechnologies

• Transforming them intocustomer-driven products.

We offer a wide range of specialtychemicals & pyrimidines for manyclients under secrecy agreements.Strict confidentiality & theprotection of the commercial &technical interests of our clienteleare of paramount importance to us.We have demonstrated bothintegrity & reputation in this field.

PRINCIPAL CONTACT

Sajjan India Limited

Matulya Centre, # 2 Ground Floor,

Senapati Bapat Marg, Lower Parel

Mumbai 400 013, India

Tel: + 91 22 24 97 44 00 Fax: + 91 22 24 95 05 88

Email: [email protected] Website: www.sajjan.com

Specchem magazine Outsourcing special publication page 13|

Located in the east of France onthe Swiss-German border, Potasseet Produits Chimiques SAS (PPC) isa combined research and produc-tion centre. PPC has forged anexcellent reputation thanks to twocenturies of know-how and itshighly skilled workforce. Our corecompetences are bromination andchlorination. This is emphasised byour production of chlorine on siteand our capacity to recover bro-mide residual solutions.

PPC Fine Chemicals division providesglobal facilities and expertise to helpyou at every step of the product devel-opment cycle, from contract researchthrough process development and fastscale-up from laboratory to manufac-turing volumes.

Our objective is to provide the bestsolution to all our customers’ needsin terms of manufacturing quality,reliability and confidentiality, while atthe same time satisfying the environ-mental and safety requirements.

When we use our expertise to meetyour needs, innovation yields success.

A full tool box for customised solutionsHigh-level core competencies• Research and development laboratory

experts • Analytical scientists • Pilot plant chemists/engineers • Production plant chemists/engineers

Non-cGMP capabilities• Synthesis laboratories• Multi-purpose kilo-lab• Pilot plant 1m3

• Multi-purpose production• Reaction vessels (up to 180 m3)

Potasse et ProduitsChimiques (PPC)Where chemistry advances

Air sensitive synthesisAlkylationAminationBleach oxidationBrominationChlorinationCyclizationDehydrobrominationDehydratationEsterificationEther formationFriedel-Crafts reactionHoffman degradation

HydrobrominationIodinationMesylation, TosylationMethoxylation, PropoxylationMethylationMOC, BOC protectionOxidationPhosphorylationReductionTranshalogenationVilsmeier reactionWittig reaction… and others

Technologies

PRINCIPAL CONTACT

PPC - Potasse et Produits Chimiques SAS

95 rue du General de Gaulle

P.O. 60090

F- 68802 Thann Cedex, France

Tel: +33 (0)3 89 38 44 44 +33 (0)3 89 38 46 00

Fax: +33 (0)3 89 38 46 01

Email: [email protected] Website: www.ppchemicals.com

• ISO 9001• ISO 14001• Responsible Care®

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Schirm GmbH

PRINCIPAL CONTACT

Dr. Martin Schaich

Schirm GmbH

Geschwister-Scholl-Straße 127

D-39218 Schönebeck / Elbe

Germany

Tel: +49 3928 456 360 Fax: +49 3928 456 300

Email: [email protected] Website: www.schirm.com

PRINCIPAL CONTACTDr Kate Pepper

Prestonhall Industrial Estate,

CUPAR, Fife,

KY15 4RD. Scotland.

Tel: +44 (0) 1334-657655 Fax : + (0) 1334-657665

Email : [email protected]

Website: www.standrewschemtech.co.uk

Specchem magazine Outsourcing special publication page 14|

The Schirm Group was estab-lished in 1957 as a packagingcontractor. Today, the companyis a full-service manufacturingpartner for the chemical indus-try. Our scope of services com-prises custom synthesis in ourown multi-purpose plant, pro-cessing of solids and liquids,formulation of agrochemicalsand packaging of final prod-ucts, as well as storage, labsupport and dispatch of sam-ples. Schirm operates threesites in Germany and one inthe US.

Synthesis offer:! reactions with isocyanates! reactions with phenols! reactions with aldehydes! reactions with cyanamide! polymerisations! active substance purification! synthesis route development

Processing offer:! mixing! milling/micronisation! sieving

! compacting! pelletising! extruder granulation! spray granulation ! drying

Formulation offer:! WG, WP! EC, SC, SL, SE, EW ! pastes! formulation development

Packaging offer:! 0.5g to bulk / solids and liquids! standard & special packaging! water soluble/ low melting film

Additional offers:! dangerous goods storage! dispatch of samples! analytics support! sourcing of active ingredients! packaging design support

Certificates! ISO 9001, 14001, 18001 ! audited by numerous leading

chemical companies

We look forward to serve you.

As a dynamic and highly skilledteam of 16 (including 5 PhDgraduates), our goal is to pro-vide fast and effective synthesisof fine organic intermediatesfor the chemical and alliedindustries.

Our team has over 100 years ofexperience, in both academic andindustrial areas, giving us a strongproblem solving capability forwhich we have become renowned.

We specialise in the research anddevelopment of procedures for upto multi hundred kilo productionfrom gram-scale methodologyeither provided by clients, obtainedfrom literature or developed in-house.

All projects are carried out understrict confidentiality and we prideourselves on maintaining closeworking relationships with all ofour clients to mutual benefit.

World-class Custom Synthesis

Our well equipped pilot plant includes:! Two 50 l cryogenic vessels ! Five glass-lined reactors (75-

900l capacity)! 600 l stainless steel reactor! 200 and 900 l vessels capable of

hydrogenation (up to 3 and 6 barrespectively)Our laboratory scale capabilities include:! Microwave synthesis! Ozonolysis! Biotage chromatography system

We have chemical expertise in anumber of areas including nitra-tion, halogenation, oxidation,reduction and the use of pyrophor-ic reagents as well as many more.

Working under new management,the company is looking to expandits portfolio and invites newenquiries to Dr Kate Pepper.

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Page 15: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

As a specialist in custom manufactu-ring, Saltigo provides tailor-made so -lutions for your specific requirements.Supplying a world class range of highquality chemical intermediates andfinal products we already serve custo-mers active in markets as diverse as:cosmetic & personal care, flavors &fragrances, feed & food ingredients,polymer additives and auxiliaries,high-tech monomers, electronic che-micals, dyes, pigments, photo andothers. Saltigo adds value and flexibi-lity to your speciality chemicals' busi-ness, providing a large portfolio ofmulti-customer products. With our fullservice you save time and money rightfrom the start. Saltigo – our focus isyour success!

our focus, your success

tailor-made specialty chemicals

proven track record in specific industries

customized solutions

SALTIGO GMBH | KATZBERGSTR. 1 | 40764 LANGENFELD / RHEINLAND | GERMANYWWW.SALTIGO.COM | PLEASE CONTACT: +49 - 21 73 - 2 03 31 54 OR [email protected]

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Page 16: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

Tokyo ChemicalIndustry Co., Ltd.Tokyo Chemical Industry Co.,Ltd., known as TCI, is a leadingJapanese chemicals producerwith over 60 years’ experienceof reagents and specialitychemicals. Headquartered inTokyo, Japan, with productionfacilities in Tokyo, the USA(Oregon) and China (Shanghai),TCI boasts a unique specialityproduct portfolio comprisingover 20,000 organic laboratorychemicals.

TCI has earned an internationalreputation in the provision of high-quality bulk manufacturing andcustom synthesis services. Ouradvanced proprietary technologiescan be applied to the needs ofyour individual project, and westand ready to service contracts ofany size, from milligrams to kilo-grams, up to multi-tonne scale.We offer a full scale-up servicestarting with small volumes for lab-oratory testing, moving on to kilo-grams and more as your projectgrows.

TCI earned ISO 9001:2000 accred-

itation in 2002 and ISO14001:2004 in 2006, reflecting itsfocus on customer satisfactionthrough total quality and environ-mental management. FDA- inspect-ed cGMP facilities are available inJapan and the USA to supportevery area of your work.

Your business, and ours, stands orfalls on quality. And no-one takesQuality Control more seriously thanTCI. Our QC procedures are rigor-ous and extensive and we alwaysoperate to the highest standards.

Your outsourcing needs a reliableand professional partner thatmatches technical expertise and tal-ented people with flexible, world-class production, all handled withcomplete confidentiality. If yourrequirement is for complex, multi-step synthesis or an application-spe-cific product made to high specifi-cation, for use in pharmaceutical,agrochemical, electronic or cosmet-ic applications, then you need lookno further than TCI.

TCI is an Ideal partner for you.

PRINCIPAL CONTACTTokyo Chemical Industry Co., LtdGlobal Business Department

4-10-2 Nihonbashi-honcho, Chuo-ku, Tokyo 103-0023, Japan

Tel: +81-(0)3-5640-8878 Fax: +81-(0)3-5640-6902

Email: [email protected]

Website: www.tci-asiapacific.com

Specchem magazine Outsourcing special publication page 16|

Société Suisse des Explosifs Group

ValsynthèseValsynthèse was established in1983 as a subsidiary of SociétéSuisse des Explosifs. The broadexpertise acquired by the groupin the field of explosives sinceits foundation in 1894 todayallows Valsynthèse to positionitself as an expert in hazardouschemistry (e.g. nitration, oxida-tion and diazotisation).

Valsynthèse is dedicated to customsynthesis and contract manufactur-ing of intermediates and APIs. Wecan provide our customers with acomprehensive offer from processdevelopment and piloting to indus-trial production.Our servicesinclude the prepa-ration (includingValidation batches,stability tests) andsubmission ofDMFs. Our primeobjective is astrong partnershipwith our cus-tomers. We areready to meettheir expectationsthrough confiden-tiality responsive-ness, superiorquality and ethicalperformance.

Valsynthese is cer-tified to ISO 9001and is cGMPapproved.

PRINCIPAL CONTACTHelmut Zimmermann, Business Development Manager

Valsynthèse Ltd

SSE Group

P.O. Box 636

CH-3900 Brig Switzerland

Tel: +41 27 922 7136

Fax: +41 27 922 7200

Email: [email protected]

Website: www.valsynthese.ch

Both the principle of safety andenvironmental protection and acommitment to the ResponsibleCare programme are an integralpart of the in place quality system.We own facilities for the treatmentsof acids and residual water, distilla-tion towers for organic solvents andan incinerator for waste products.

Recently, Valsynthèse has become ajoint-venture partner in ChemfinetServices, the premier provider ofweb-based solutions to the customchemicals and fine chemicals indus-tries (www.chemfinet.com).

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Page 17: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

The WeylChem group offerscustom-made and catalogueproducts from its US plants inElgin and Augusta, fromMannheim and Frankfurt inGermany and from Thann inFrance.

These assets provide access to abroad range of cutting-edge tech-nologies.R&D labs, pilot facilities and techni-cal reactor equipment in the rangeof 6-16 m3 are available at all ofthe sites, coordinated via a globalmanagementteam.

Core technologies are:

• Photochlorination,

• Catalytic Oxidations,

• Halex exchange reaction,

• Bromination

• Diazotization/Sandmeyer,

• Grignard Chemistry,

• Ullmann coupling,

• Allylations ,

• Skraup reaction,

• Enzymatic Reductions.

Weylchem is part of theInternational Chemical InvestorsGroup (www.icig.de)which is a privately held invest-ment company focusing on mid-sized chemicalsbusinesses. Since its inception in2004, ICIG has acquired 15 inde-pendentchemicals businesses, with totalsales of approximately !600 million.

PRINCIPAL CONTACTWeylChem Frankfurt GmbH

Dr. Wolfgang Mueller

New Business Development

Stroofstraße 27, 65933

Frankfurt am Main

Tel.: +49 69 3800 2109

Fax: +49 69 3800 2103

E-Mail: [email protected]

Website: www.weylchem.com

Specchem magazine Outsourcing special publication page 17|

Your pathfinder forbest solutions 2009

15 – 17 APRIL 2009HALL 1, BOMBAY EXHIBITION CENTRE NSE GOREGAON (E),MUMBAI

www.chemspecindia.com

Contact the sales team John LaneTel: +44 (0) 1737 855 [email protected]

In association with

Organised byOfficial media partner

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Page 18: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

Expertise Matrix

Specchem magazine Outsourcing special publication page 18|

AcylationAlkylation AminationBlendingBrominationCarboxylationChiral SynthesisChlorinationCondensationContract ResearchCyanationDehydrogenationDiazotisationDistillationEsterificationFermentationFluorinationFractionationFriedel-Crafts ReactionsGranulationHydrogenationNitrationOxidationPhosphorylationPhosgenationPolymerisationPowder ProcessingReductionRegulatory Affairs ConsultancySeparationSulphonationThiocarbonylationThiolationOther

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p18_OS_Matrix08_blank.qxp 7/8/08 16:21 Page 18

Page 19: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

AMI Drugs & Speciality Chemicals PVT.LtdContact: Naresh Vaghasia2nd Floor, Prestige Plaza40, Urmi SocietyNr Urmi Cross Road, BPC Road,Akota, Baroda- 390020Gujarat, IndiaTel: +91 265 3052103Mobile: +91 98241 47318 or +91 98240 09384Fax: +91 265 3052104Email: [email protected]: www. amidrugs.com

CU Chemie Uetikon GmbHContact: Dr. Hendrik Baumann, Commercial DirectorRaiffeisenstrasse 4,77933 Lahr, GermanyTel: +49 7821 585 0 Fax: +49 7821 585 230Email: [email protected]: www.uetikon.com

Dishman Europe Ltd.Contact: Christian Dowdeswell120 New Cavendish StreetLondon W1W 6XX , UK

Tel: +44 (0)20 7323 0608Fax: +44 (0)20 7323 0609Email: [email protected]: www.dishman-europe.com

Dottikon Exclusive Synthesis AGContact: Gabriela SchuppliHembrunnstrasse 175605 Dottikon SwitzerlandTel: +41 56 616 81 11Fax: +41 56 616 81 20Email: [email protected]: www.dottikon.com

DyStar Texilfarben GmbH & Co. Contact: Dirk De VosDeutschland KG65926 Frankfurt, GermanyTel: +49 (0) 69 2109 2288Email: [email protected]: www.dystar.com

Gee Lawson LimitedContact: Mike NormanFirst Floor, Melville House 8-12 Woodhouse RoadLondon N12 0RG, UKTel: +44 (0)20 8343 5400 Fax: +44 (0)20 8445 7529Email: [email protected] Website: www.geelawson.co.uk

Genzyme Pharmaceuticals675 West Kendall StreetCambridge, MA 02142 USA Tel: :+1 800 868 8208 or +1 617 374 7248Fax: +1 617 768 9765Email: [email protected]: www.genzymepharmaceuticals.com

Jai Research FoundationOff. N.H. No. 8, Near Daman Ganga BridgeValvada. 396 108 Dist. Valsad, Gujarat ,India Tel: +91-260-6540242 / 6543242 Fax: + 91-22-66466119 Email: [email protected] Website: www.jrfonline.com

JSC InternationalContact: Lucy CroucherSimpson House, Windsor CourtClarence Drive, Harrogate, HG1 2PE, UKTel: +44 (0) 1423 520245Fax: +44 (0) 1423 520297Email: [email protected]: www.jsci.co.uk

NOTOX B.V.Contacts: Ing. Chris de Ries & Ir. Danny HaackeP.O. Box 34765203 DL ‘s-Hertogenbosch The NetherlandsTel: + 31 73 640 6700Fax: + 31 73 640 6799E-mail: [email protected] &[email protected]: www.notox.nl

Neogen Chemicals Ltd115, Vardhaman Industrial Complex Agra Road , Thane (W) - 400601Maharashshtra State, India Tel: + 91 022 21723716Fax: + - 91 022 21721083Email - [email protected] -www.neogenchem.com

OmniChemIndustrial Research Park FlemingB-1348 Louvain-la-NeuveBelgiumTel: +32 10 483111Fax: +32 10 452553Email: [email protected]: www.omnichem.be

ORGANICA Feinchemie GmbH Contact: Werner Salomon Marketing and Sales DirectorKunstseidestr. 5D – 06766 Bitterfeld-WolfenGermanyTel: +49 3494 636389Fax: +49 3494 637239Email: [email protected] Website: www.organica.de

Contact Details p19_20_OS_Contact_page08.qxp 8/8/08 15:20 Page 2

Page 20: Outsourcing - ORGANICA Feinchemie GmbH Wolfen · Headquartered in Ahmedabad, Gujarat, India, Dishman started as a PTC producer and later applied this experience to the manufacture

Contact Details

PPC - Potasse et Produits Chimiques SAS95 rue du General de GaulleP.O. 60090F- 68802 Thann Cedex, FranceTel: +33 (0)3 89 38 44 44 +33 (0)3 89 38 46 00Fax: +33 (0)3 89 38 46 01Email: [email protected]: www.ppchemicals.com

RCC LtdZelgliweg 1, ItingenCH-4452, SwitzerlandTel: +41 (0)61 975 11 11Fax: +41 (0)61 971 52 84Email: [email protected]: www.rccltd.ch

Sajjan India Limited Matulya Centre, # 2 Ground Floor,Senapati Bapat Marg, Lower ParelMumbai 400 013,IndiaTel: + 91 22 24 97 44 00Fax: + 91 22 24 95 05 88Email: [email protected]: www.sajjan.com

Saltigo GmbHKatzbergstr. 140764 Langenfeld,Rheinland GermanyTel: 49 - 2173 - 2033 0Email: [email protected]: www.saltigo.com

Schirm GmbHContact: Dr. Martin Schaich Geschwister-Scholl-Straße 127D-39218 Schönebeck/Elbe, GermanyTel: +49 3928 456 360Fax: +49 3928 456 300Email: [email protected]: www.schirm.com

St Andrews ChemTech InternationalLimited

Contact: Dr Kate PepperPrestonhall Industrial Estate,CUPAR, Fife,KY15 4RD, ScotlandTel: +44 (0) 1334-657655 Fax :+44 (0) 1334-657665Email : [email protected]: www.standrewschemtech.co.uk

Synkem47 rue de Longvic - B.P. 5021301 Chenove Cedex, FranceTel: + 33 3 80 44 72 87

Fax: + 33 3 80 44 74 20Email: [email protected]: www.synkem.com

Tokyo Chemical Industry Co., Ltd.Global Business Department4-10-2 Nihonbashi-honchoChuo-ku, Tokyo 103-0023 JapanTel: +81 (0)3 5640 8878Fax: +81 (0)3 5640 6902E-mail: [email protected]: www.tci-asiapacific.comTCI Europe N.V. Tel: +32 (0)3 735 07 00/+00 80046 73 86 67Fax: +32 (0)3 735 07 01E-mail: [email protected]

Website: www.tcieurope.euTCI Deutschland GmbHTel: +49 (0) 6196 998678-0Fax: +49 (0) 6196 998678-1E-mail: [email protected] Chemical Industry UK Ltd.Tel: +44 (0)1865 784560 Fax: +44 (0)1865 784561 E-mail: [email protected]

TSGEContact: Vicky AtkinsonConcordia HouseSt James Business Park Grimbald Crag Court, KnaresboroughNorth Yorkshire HG5 8QB, UKTel: +44 (0) 1423 799 633Fax: +44 (0) 1423 797 804Email: [email protected]: www.TSGEurope.comTSGE Iberia S.L.Tel: +34 984 051 293Fax: +34 984 051 293E-mail: [email protected] Website:www.TSGEIberia.com

Valsynthèse LtdContact: Helmut ZimmermannBusiness Development ManagerP.O. Box 636CH-3900 BrigSwitzerlandTel: +41 27 922 7136Fax: +41 27 922 7200Email: [email protected]: www.valsynthese.ch

WeylChem Frankfurt GmbHContact: Dr. Wolfgang MuellerNew Business DevelopmentStroofstraße 27, 65933 Frankfurt am MainGermanyTel.: +49 69 3800 2109Fax: +49 69 3800 2103E-Mail: [email protected]: www.weylchem.com

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