p < 0.0001

0.0 0.2 0.4 0.6 0.8 1.0 Progression-free survival 0 20 40 60 80 100 120 140 160 180 Duration (months) P < 0.0001 4-year survival rate 27.9% 63.8% 96.6% A high intermediat low 0.0 0.2 0.4 0.6 0.8 1.0 Cancer-specific survival 0 20 40 60 80 100 120 140 160 180 200 Duration (months) P < 0.0001 4-year survival rate 65.0% 81.6% 100% B high intermediat low 0.0 0.2 0.4 0.6 0.8 1.0 Overall survival rate 0 100 200 Duration (months) P = 0.0074 4-year survival rate 63.4% 70.7% 85.6% C high intermediat low Supplementary Figure 1 Shiota et al. Supplementary Figure 1. Prognostic stratification of patients with prostate cancer treated with CAB according to J-CAPRA score. (A)-(C) PFS (A), CSS (B), and OS (C) in patients stratified by categorized scores are shown.

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Supplementary Figure 1 Shiota et al. A. 4-year survival rate 27.9% 63.8% 96.6%. P < 0.0001. B. 4-year survival rate 65.0 % 81.6% 100%. P < 0.0001. C. 4-year survival rate 63.4% 70.7% 85.6%. P = 0.00 74. - PowerPoint PPT Presentation

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Duration (months)

P < 0.0001

4-year survival rate

27.9%

63.8%

96.6%

high

intermediate

low

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65.0%

81.6%

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intermediate

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Duration (months)

P = 0.0074

4-year survival rate

63.4%

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intermediate

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Supplementary Figure 1 Shiota et al.

Supplementary Figure 1. Prognostic stratification of patients with prostate cancer treated with CAB according to J-CAPRA score. (A)-(C) PFS (A), CSS (B), and OS (C) in patients stratified by categorized scores are shown.

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.75

1.0

ensi

tivity

0.00 0.25 0.50 0.75 1.001-Specificity

Prediction of CSS using continuous J-CAPRA score

P = 0.2533

1996-2005 ROC area: 0.879

2006-2012 ROC area: 0.803

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.25

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.75

1.0

ensi

tivity

0.00 0.25 0.50 0.75 1.001-Specificity

Prediction of CSS using categorized J-CAPRA score

P = 0.3371

1996-2005 ROC area: 0.821

2006-2012 ROC area: 0.759

Supplementary Figure 2 Shiota et al.

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0.00 0.25 0.50 0.75 1.001-Specificity

1996-2005 ROC area: 0.895

2006-2012 ROC area: 0.876

Prediction of PFS using continuous J-CAPRA score

P = 0.7444

0.0

.25

0.5

.75

1.0

ensi

tivity

0.00 0.25 0.50 0.75 1.001-Specificity

Prediction of PFS using categorized J-CAPRA score

P = 0.2251

1996-2005 ROC area: 0.886

2006-2012 ROC area: 0.812

Supplementary Figure 2. Validation of J-CAPRA score. Receiver operator characteristic curves of J-CAPRA score (left panel, continuous scores; right panel, categorized scores) among patients in 1996-2005 and 2006-2012 for the prediction of PFS (A) and CSS (B). The curves describe the association between sensitivity and specificity.

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