p. 1

FAQs- before analyzing your sample

p. 2

Temperature (thermal degradable?) Split or splitless Split ratio Injection volume

FAQs- injection port

p. 3

Split/splitless injection port

p. 4

Column selection Polarity (DB5-ms, DB-17, DB-Wax) Chirality (HP-Chiral ß column) cis/trans form (HP-88)

Length of column H = L/N

FAQs –column and oven

p. 5

FAQs-peaks

p. 6

Experimental resolution

p. 7

van Deemter equation

p. 8

FAQs-peaks

p. 9

FAQs-peaks

p. 10

FAQs-peaks

p. 11

Detection limit for trace analysis

LOQMDL

p. 12

Detection limit for trace analysis

MDL

p. 13

Detection limit for trace analysis

Limit of linearity (LOL)

Limit of quantitation (LOQ)

Method detection limit (MDL)

22

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p. 14

Retention time only Dual column with certify reference materials

Retention time with mass spectrum Identification power of ion (at least 4) MS: 1 IP MS/MS and HR MS: 2 IP

FAQs –qualification

p. 15

Quality assurance systematic processes that provide confidence in

a suitability of analytical process for its intended purpose.

Blank (field, reagent, matrix) Calibration check sample

FAQs –QA/QC

p. 16

Quality control systematic processes that ensure test results are

designed and produced to meet the requirements Spike Duplicate Spike duplicate

FAQs –QA/QC

p. 17

Reagent blank Calibration C1-C5 (at least 5 points within 1 order) Calibration check CK1

Sample S1-Sn ( 10 for environmental analysis, 20 for common ≦ ≦practice)

Spike SK1

Duplicate D1

Spike duplicate sample SD1

Sample Sn+1-S2n

Spike SK2

Duplicate D2

Spike duplicate sample SD2

Calibration check CK2

FAQs –sequence

p. 18

An internal standard in analytical chemistry is a chemical substance that is added in a constant amount to samples, the blank and calibration standards in a chemical analysis.

This substance can then be used for calibration by plotting the ratio of the analyte signal to the internal standard signal as a function of the analyte concentration of the standards.

FAQs –internal standard

p. 19

This is done to correct for the loss of analyte during sample preparation or sample inlet. The internal standard is a compound that matches as closely, but not completely, the chemical species of interest in the samples, as the effects of sample preparation should, relative to the amount of each species, be the same for the signal from the internal standard as for the signal(s) from the species of interest in the ideal case.

Adding known quantities of analyte(s) of interest is a distinct technique called standard addition, which is performed to correct for matrix effects.

FAQs –internal standard