pandora-id-net pan-african network for rapid research...
TRANSCRIPT
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Pan-African Network for Rapid Research, Response, Relief
and Preparedness for
Infectious Diseases Epidemics
Francine Ntoumi PhD, HDR, FRCPCoordinator
Fondation Congolaise pour la Recherche Medicale, Brazzaville, Congo
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EDCTP Call RAI2016E
IPANDORA ID-NET is a ‘ONE Human and Animal HEALTH’ multidisciplinary consortium of 24 partner institutions (15 African and 9 European) derived from 9African and 4 European countries.
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The Consortium
Our partners are from:
– WEST AFRICA: 1).Sierra Leone, 2).Nigeria, 3).Ghana
– CENTRAL AFRICA: 4) Republic of Congo, 5) Gabon
– EAST AFRICA: 6) Sudan, 7) Uganda, 8) Tanzania
– SOUTHERN AFRICA: 9) Zambia
– EUROPE: 10). United Kingdom, 11). Italy, 12). Germany and 13) France.
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Overall Aim
To strengthen regional and pan-African
capacities and systems for enabling rapid
and effective response to emerging and re-
emerging infectious diseases threats arising
from within Africa, or those imported from
overseas.
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Specific objectives
• To develop and setup robust ‘ready to go within 48-72 hours’ outbreak rapid response teams, at each of the four African regions (West, Central, East and Southern Africa)
• To strengthen capacities for conduct of research (multidisciplinary operational, anthropological, social science)
• To train and empower scientists, healthcare workers, laboratory personnel, clinical trialists, ethicists and social scientists
• To engage stakeholders and global public health agencies at the highest level during all stages of our program.
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Workpackages
• WK1: Coordination, administration, advocacy, networking
• WK2: Capacity building and training
• WK3: Epidemiological, clinical and surveillance pathogens studies
• WK4: Zoonotic One Health (Human-animal) interface studies– Natural studies
• WK5: Clinical trials on existing and sporadic zoonotic disaeses
• WK6: Data management, sharing and reporting
• WK7: engaging policy makers, global public health bodies and communities and ethical, administrative, regulatory and operational obstacles during outbreaks
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Strategy
Each Africa Region will have focal coordinating institutions:
• West Africa(Nigeria)-Irrua Teaching Hospital. • Central Africa(Congo)-Fondation Congolaise pour la
Recherche Medicale• East Africa (Sudan)- Institute of Endemic Diseases,
(Tanzania)- National Institute for Medical Research• Southern Africa(Zambia)-University of
Zambia/University Teaching Hospital (includes veterinary partners).
Each region will have lead clinical site, satellite clinical sites, an animal health institution and a reference laboratory.
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Organisation structure
• The Coordinator will be responsible for the overall administrative, financial, legal, contractual aspects of the consortium in accordance with the EDCTP contract
• The coordination team (deputy-coordinators , project managers, finance managers)
• Executive board: Decision making body composed of coordinating team and representative of each partner
• External Scientific Advisory Group advises the Executive Board and ensures objectivity and inputs into a high standard of scientific excellence
• Project coordinating officers ( workpackage leaders) will provide leadership of the consortium, running all aspects of the project coordination of research and innovation tasks.
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Implementation - Activities
• Areas:• Human Health
• Animal health
• Ethics and social sciences
• Policy makers and community involvement
• Cross-cutting activities• Epidemiology and surveillance
• Laboratory
• Training and capacity building
• Coordination, dissemination and information
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WK2 - Training and capacity building
▪ Training and tailored regional workshops on specific and cross-cutting areas
• Develop instructional training video (on line) s materials.
• Educational and academic individual training.
• Development/improvement of infrastructure
• Establishment of Biobank(s)
• Increase laboratory diagnostic capability
• Establishment of 2 new mobile lab units in Africa
• Conduct Quality assurance and quality control processes for accreditation
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WK3-Establishment of Outbreak response team
• Identify key institutions who can develop their existing capacity and capability.
• To strengthen networks with existing agencies already active in this field to ensure synergy and maximum collective benefit.
• Between outbreaks, epidemiological studies on the sporadic and continuing infectious outbreaks
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WK4- Animal health WK5-surveillance and clinical trials
• Needs assessment on key zoonoses in the participant countries, identification of key gaps, opportunities, clinical trials
• Epidemiological studies and determining the risk factors of zoonotic diseases with potential to cause large epidemics.
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WK6- Data collection and management
• Strengthen systems for data collection
• Enhance the utilisation of surveillance data
• Harmonizing data collection platforms
• Establishing best practices in data collection, curation and analysis
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WK7- Ethics
• Development of a an adaptive trial platform and pre-approval by local ethics committees.
• Review recommendations from Ebola recent outbreaks
• Organise deliberative workshops and consensus summit for regulators and ethics committees
• Developing ethics expertise in ethics of research in emergency situations –including operational activities and interventions used by rapid response teams
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WK7-Engaging stakeholders and Communities
• To understand perceptions of EID risks and the level of support for specific interventions.
• To identify the existing multi-sectoralstrategies for building appropriate levels of preparedness and response to EID outbreaks.
• To investigate the barriers that impede rapid and effective responses to EID outbreaks
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Synergies for developing activities
• The four EDCTP regional networks of Excellence
• ALERRT
• Regional health organizations (OCEAC, WAHO,etc.)
• International organization (AFRO, NEPAD, AFRICA-CDC)
• Other initiatives
• Local private sector
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Special thanks to coordination team
Sir Ali ZUMLA
Prof. Giuseppe IPPOLITO
Dr. Francesco VAIRO
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Zikomo Kwambhiri
GraziasDěkujiKiitos
Terima kasihShukran gazilanJazakallah kheir
Thank youAsante
Merci beaucoupDankie