Hafiza madiha jaffarM.Phil (HND)

Government college university Faisalabad

PAPAYA DRINK

ROAD MAP

introduction classification objective About the product Material use

budgeting method Benefits of ingredients

Nutrition summary

Active ingredients

Health benefits

Mechanism of action

Papaya Drug Interactions

SIDE EFFECTS references

Classsification• Kingdom Plantae• Subkingdom Tracheobionta• Superdivision Spermatophyta• Division Magnoliophyta• Class Magnoliopsida• Subclass Dilleniidae• Order Violales• Family Caricaceae• Genus Carica• Species Carica papaya

INTRODUCTION• FAMILY: Caricaceae

SCIENTIFIC NAME: Carica papaya L.ORIGIN: American tropical lowlands

• Carica papaya, is a powerhouse of nutrients, it contains both macro and micronutrients and several enzymes.

• Papaya leaves are used to make medicine and leaves extract having potential Activity of increasing platlets against dengue fever found in their study. . (Ahmed et al)

• it`s used for preventing and treating gastrointestinal tract disorders, intestinal parasite infections. It is also used for nerve pains .

Continue…• The enzymes include papain , chymopapain.• Possible mechanisms of action include the activity of proteolytic

enzymes, chemopapain and papain, as well as an antimicrobial activity.papain improved digestion of protein.

• Due to its antioxidant properties, papaya prevents the oxidation of cholesterol. Also, the high fiber content helps in lowering the bad cholesterol level. also contains several protein-digesting enzymes -papain and chymopapain which are responsible to lower inflammation and improves healing from burns.

Nutrition Summary• 100g of papaya gives

• Total Calories 39kcal• Protein 0.5 g• Fat 0.4 g• Carbohydrate 9.8 g

Papaya, raw Nutritional value per 100g (3.5 oz)

ENERGY 163kJ (39 kcal)

CARBHOHYDRATES 9.81g

SUGARS 5.9 g

DIETARY FIBRE 1.8 g

FAT 0.4 g

VITAMIN A EQUIV. 328 μg (41%)THIAMINE (VIT.B1) 0.04 mg (3%)RIBOFLAVIN (VIT.B2) 0.05 mg (4%)NIACIN (VIT. B3) 0.338 mg (2%)VITAMIN B6 0.1 mg (8%)FOLATE(VITB9) 38 μg (10%)VITAMIN C 61.8 mg (74%)CALCIUM 24 mg (2%)IRON 0.10 mg (1%)PHOSPHOROUS 5 mg (1%)

Active ingredients• Papaya contains a chemical called papain, which is commonly

used as a meat tenderizer.• Papain breaks down proteins, carbohydrates, and fats. That’s

why it works as a meat tenderizer. However, papain is changed by digestive juices, so there is some question about whether it could be effective as a medicine when taken by mouth.

Papaya also contains a chemical called carpain. Carpain seems to be able to kill certain parasites, and it might affect the central nervous system.

health benefits and uses of papaya

•Diabetes• lower Blood Pressure(A.Eno. and R.Konya,2000)•Asthma prevention•Reduced risk of certain cancer like prostate cancer•lower inflammation and improves healing from burns•lowering the bad cholesterol level.

Continue….• Weight Loss • Morning Sickness • Osteoporosis• Anti-ageing • Reduced Constipation• improve Immunity • Shampoos• Reduced Kidney disorder• Intestinal Worms

Mechanism of action

• Major digestion problems occur when undigested food reaches lower intestine. This happens particularly in case of eating large quantities of meat with fast speed. The natural digestive enzymes produced in the pancreas and stomach acids generally can’t meet the digestion requirements under those conditions. (Tenenhouse, Harriet S. Deutsch, H. F.1966)

• Unlike carbohydrates, which get digested by saliva produced during chewing, protein do not get digested by saliva. Protein digestion has a different mechanism. Protein gets digested with the help of proteolytic enzymes produced in the pancreas.

• Papaya helps digesting proteins well because Papain is similar other types of enzymes made in the pancreas that help our bodies digest meat. But, these enzymes need acid for activation and papain can work even without the presence of acid.(Tsai C C, Linn C C)

• digestive benefits of papaya comes from various proteolytic (protein digesting) enzymes.  papain which is very similar to the digestive juice pepsin.  An important characteristic of papain is that it breaks down proteins.

•  It breaks complex bonds of protein down to individual amino acids which are ready for use for repair and growth of the body

Cont……..

OBJECTIVESTo develop a nutraceutical drink for improve protein digestion.

Nutritional profiling of papaya nutraceutical drink

To assess the storage stability of papaya nutraceutical drink

ABOUT THE PRODUCT

• Papaya• Orange• Almond• Stevia

This product contains

BENEFITS OF INGREDENTS PAPAYA

1) Effective in combating obesity 2) Contains essential vitamins and minerals

1)Prevent cancer 2)good for skin 3)diabetes management 4)prevent formation of kidney stone

ALMOND 1)Regulation of cholesterol 2)Bone Health 3)Good for

heart

STEVIA Natural sweetener which helps to lower blood sugar level. Contains trace

minerals like zinc, chromium

MATERIALS USEDIngredients Amount 

Papaya pulp 500g

Stevia ½ tsp (2.5g)

Orange pulp 250g

Almond

Preservative

10-12………

 BUDGETINGIngredients PricePapaya Rs.

Orange Rs.

Almond Rs.

Stevia Rs.

Preservative Rs. Packaging material Rs.

Total

Method

Make pulp of fresh papaya and orange

Grind almond after

removing peel

Mix the ingredient as per standard

Add stevia and filter in

home

and enjoy

Papaya Drug InteractionsTotal of 3 drugs (6 brand and generic names) are known to interact

with papaya.Medications known to interact with papaya• Anisindione• Miradon (anisindione)• Dicumarol • Coumadin (warfarin)• Jantoven (warfarin)• Warfarin (Papaya might increase the effects of warfarin and increase the

chances bleeding)

PAPAYA SIDE EFFECTS• when taken in large amount of papaya cause damage the esophagus.

Irritate skin  as papaya latex when apply on skin.• Unsafe during pregnancy (papain might poison the fetus or cause birth

defects) and breast feeding.(Kadry Mohamed Sadek.2012)• DiabetesPeople (with diabetes blood sugar as adjustments to medications

might be needed)• Low blood sugar • Papain allergy • Latex allergy• Surgery (papaya might affect blood sugary during and after surgery. stop 2

weeks before surgery)

References• Ahmed, N., H.Fazal, M. ayaz,B.H.Abbasi, I. Mohammad and

L.fazal.2011.Asian pak J Trop BioMed.1 (4), 330-333.• Kadry Mohamed Sadek.2012.Antioxidant and immunostimulant

effect of Carica papaya L. aquous extract Acrylamide intoxicated rats, 20(3), 180-185

• A.Eno. and R.Konya,2000.Blood pressure depression by the fruit juice of Carica Papaya.

• Tsai C C, Linn C C, Papaiya: Boosting Enzyme, Journal of Ethnopharmacology, 44 (1996) 56.