paracelsus paracelsus was so grandiose and perhaps just a little bit gross

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A Small Dose of Toxicology Welcome to Small & Large Dose of Toxicology Paracelsus Paracelsus was so grandiose And perhaps just a little bit gross Manure, blood, and sand and thus you create man But what makes it a poison is dose! The Undecided Dose Too much of a thing makes you blue But not having it can kill you too Too much or too little Let's not be so fickle We'll go Dutch and divide it by two. Limericks by Toni Hayes

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Limericks by Toni Hayes. Paracelsus Paracelsus was so grandiose And perhaps just a little bit gross Manure, blood, and sand and thus you create man But what makes it a poison is dose!. The Undecided Dose Too much of a thing makes you blue But not having it can kill you too - PowerPoint PPT Presentation

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A Small Dose of Toxicology Welcome to Small & Large Dose of Toxicology

ParacelsusParacelsus was so grandiose

And perhaps just a little bit grossManure, blood, and sandand thus you create man

But what makes it a poison is dose!

The Undecided DoseToo much of a thing makes you blue

But not having it can kill you tooToo much or too littleLet's not be so fickle

We'll go Dutch and divide it by two.

Limericks by Toni Hayes

A Small Dose of Toxicology Welcome to Small & Large Dose of Toxicology

A Small Dose of Toxicology Welcome to Small & Large Dose of Toxicology

A Small & Large Dose of Toxicology

Welcome !!

Introduction to the Health Effects of Chemicals

Steven G. Gilbert, PhD, DABT

www.asmalldoseof.orgwww.toxipedia.org

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Objective

Increase our understanding of how chemicals affect human health.

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Course evaluation – Very important

Other stuff!!!

Ask questions – Talk to me!!!

Logistics

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Special Thank you to:

Those that really make this happen:

Northwest Center for Occupational Health and Safety Environmental Health University of Washington

Maribeth Moore

Thanks to Organizers

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

8:00 am Registration

8:30 Welcome to “A Small Dose of Toxicology” S. Gilbert

8:40 An Introduction to Principles of Toxicology S. Gilbert

10:00 Break

10:30 Non-Cancer and Neurotoxicology S. Gilbert

11:30 Q&A Basic toxic S. Gilbert

12:00 pm Lunch – will be catered – networking time

1:00 Case Study: Health Effects of Lead S. Gilbert

2:00 An Introduction to Repro & Devel Toxicology S. Gilbert

2:45 Break

3:00 Precautionary Assessment – Beyond RA S. Gilbert

4:00 Questions and Answers all

4:30 Adjourn

A Small Dose of Toxicology

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

8:00 am Registration

8:30 Welcome S. Gilbert

8:40 Toxicology and Drug Development R. Ponce

9:30 Managing Exposure – Occupational Issues. J. Camp

10:15 Break

10:45 Nanotoxicoloogy W. Smith

11:45 Question and Answers All

12:00 pm Lunch – provided

1:00 Respiratory Toxicology M. Morgan

2:00 Pollution in People – Biomonitoring S. Gilbert

2:30 Break

2:45 Melamine Risk Assessment S. Wong

3:45 Ethical, Legal, Social Issues – e-waste S. Gilbert

4:15 Questions and Answers All

4:30 Adjourn

A Large Dose of Toxicology

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

A Small Dose of Toxicology

See: www.asmalldoseof.org -- smdose

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Small Dose of Toxicology

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Milestones of Toxicology

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

www.toxipedia.org

A free toxicology encyclopedia and resource center that anyone can edit. Toxipedia provides comprehensive, accurate, and scientifically based information on the hazards and risks of chemical and physical agents, with the goal of advancing human and environmental health. Toxipedia

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

The World Library of Toxicology

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Toxipedia suite of sites

www.ipmopedia.org

www.healthyworldtheater.orgwww.wanmec.org

www.toxipedia.org

www.wltox.org

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicologywww.wltox.org

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Connecting Gardeners and Experts for Green Gardening Solutions Identify Your Pest

Find the Right Plant Ask the Experts Garden Design Guide Indoor Pest Control

www.ipmopedia.org

Supported by Local Hazardous Waste Management Program in King County, WA.

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

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A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Healthy World Theater• http://healthyworldtheater.org

• promote awareness and understanding through the arts to create a more healthy and peaceful world

• plays, poems, jokes, fiction, music, cartoons, haiku, and even limericks

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

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A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Washington Nuclear Museum and Educational Center (WANMEC)

• http://wanmec.org

• learning from the past for a safer tomorrow

• a project of Washington Physicians for Social Responsibility - funded in part by WA DOE

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Toxipedia www.toxipedia.org

Connecting Science and People

Washington Nuclear Museum and Education Center - www.wanmec.org

Integrate Pest Managementwww.IPMopedia.org

World Library of Toxicology www.wltox.org

Healthy World Theaterwww.healthyworldtheater.org

A product of the Institute of Neurotoxicology and Neurological Disorders (INND) For more information contact Steven G. Gilbert at [email protected]

Connecting Gardeners and Experts for Green Gardening Solutions

Learning from the past for a safer tomorrow Uniting art and science for a healthy, peaceful world

Connecting Scientists and Experts to Improve Global Health

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

LDDI Consensus Statement

Scientific Consensus Statement on Environmental Agents Associated with

Neurodevelopmental DisordersDeveloped by the Collaborative on

Health and the Environment’s Learning and Developmental Disabilities

InitiativeNovember 7, 2007

http://www.iceh.org/LDDI.html

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

LDDI Consensus Statement

http://www.iceh.org/LDDI.html

Given the established knowledge, protecting children from neurotoxic environmental exposures from the earliest stages of fetal development clearly is an essential public health measure if we are to help prevent learning and developmental disorders and create an environment in which children can reach and maintain their full potential.

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

NW Public Health

See: http://healthlinks.washington.edu/nwcphp/nph/

nwph

Public Health and the Precautionary

Principle

By Steven G. Gilbert

A Small Dose of Toxicology Welcome to Small & Large Dose of Toxicology

Precautionary Principle

“When an activity raises threats of harm to human health or the environment,

precautionary measures should be take even if some cause and effect relationships are not

fully established scientifically.”

Wingspread Conference, 1998.

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Child Health

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

So Many Chemicals so Little Data

2863 above 1 Million pounds

78.2% no data

21.4% some data

12 or 0.4% good data

www.preventingharm.org

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

Nearly 12 million children (17%) under age 18 in the US suffer from one or more developmental disabilities

Learning disabilities – 5-10% of kids in public school

ADHD – 3-6% of all school kids, maybe higher

The Consequences

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

A Small Dose of – web site

A Small Dose of Toxicology

www.asmalldoseof.org

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

A Small Dose of Toxicology