paracetamol

1
Generic Name Acetaminophen/ paracetamol Brand Name biogesic Classification Analgesic, antipyretic Mode of Action Antipyretic: Reduces fever by acting directly on the hypothalamic heat- regulating center to cause vasodilation and sweating, which helps dissipate heat. Analgesic: Site and mechanism of action unclear. Ordered Dose December 6, 2015 500 mg 1 tab now Suggested Dose . 500 mg every 4 hours Indication Temporary reduction of fever; temporary relief of minor aches and pains caused by common cold and influenza, headache, sore throat, toothache (patients ages 2 yr and older), backache, menstrual cramps, minor arthritis pain, and muscle aches (patients older than 12 yr) Unlabeled use: Prophylaxis in children and patients at risk for seizures who are receiving DTP vaccination to reduce incidence of fever and pain Contraindication Contraindicated with allergy to acetaminophen. Use cautiously with impaired hepatic function, chronic alcoholism, pregnancy, lactation.

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Page 1: Paracetamol

Generic Name Acetaminophen/ paracetamol

Brand Name biogesic

Classification Analgesic, antipyretic

Mode of Action Antipyretic: Reduces fever by acting directly on

the hypothalamic heat-regulating center to cause

vasodilation and sweating, which helps dissipate

heat.

Analgesic: Site and mechanism of action unclear.

Ordered Dose December 6, 2015

500 mg 1 tab now

Suggested Dose . 500 mg every 4 hours

Indication Temporary reduction of fever; temporary relief of

minor aches and pains caused by common cold

and influenza, headache, sore throat, toothache

(patients ages 2 yr and older), backache,

menstrual cramps, minor arthritis pain, and

muscle aches (patients older than 12 yr)

Unlabeled use: Prophylaxis in children and

patients at risk for seizures who are receiving

DTP vaccination to reduce incidence of fever and

pain

Contraindication Contraindicated with allergy to acetaminophen.

Use cautiously with impaired hepatic function,

chronic alcoholism, pregnancy, lactation.

Side Effects CNS: Headache

 CV: Chest pain, dyspnea

GI: jaundice

GU: Acute renal failure, renal tubular necrosis

Hematologic: Methemoglobinemia— cyanosis;

hemolytic anemia—hematuria, anuria;

neutropenia, leukopenia, pancytopenia,

thrombocytopenia, hypoglycemia

Hypersensitivity: Rash, fever

Adverse Effects Myocardial damage

Hepatic toxicity and failure