parmetol® MBX

Fast-acting preservative with long-term protection

Many sources of

contamination:

one solution

parmetol® MBX

2

Fast germ count reduction Long-term protection Low use concentration Synergistic combination of actives Excellent pH- and temperature stability Free of formaldehyde, AOX, VOC

and alkylphenolethoxylates Conforms to ecolabel Fully BPR* supported under PT 6 | 11 | 13

Product description parmetol® MBX is a fast-acting 2 in 1 in-can preservative based on a synergistic combination of benzisothiazolone (BIT), methyl-isothiazolone (MIT) and laurylamine dipropylenediamine (BDA) with a broad spectrum of efficacy.

Contaminated process water and raw materials Microbial contamination of a product can occur during its manufacture, with the majority of contaminants being present in many different sources: • Water • Raw materials • Vessels, bulk tanks and plumbing lines • Biofilms • Ion exchanger resins and reverse osmosis membranes Moreover, moderate temperatures, neutral pH and neglected housekeeping tend to cause and support process and product contamination.

How to eliminate the risk of contamination In general oxidising and non-oxidising biocides are used to prevent products from being contaminated by microorganisms. In addition to bleaching, oxidising agents possess some severe disadvantages; many manufacturers therefore use non-oxidising in-can preservatives to treat stored raw materials, wash water and finished products. This single long-term preservative may get the job done however it may be time-consuming and the cost of long-term preservation can be quite high! That is why many manufacturers use additional agents to treat raw materials and process water in order to avoid contamination within their manufacturing process. However, this approach is inconvenient, expensive and does not ensure for comprehensive process and product security! schülke therefore offers a product solution that: • Treats contaminated process water and raw materials • Enables extensive process hygiene** • Provides synergistic in-can preservation

parmetol® MBX This innovative blend based on BDA, a fast-acting amine, and MIT/BIT, responsible for in-can preservation, kills bacteria, yeasts and moulds within process water or raw materials in only a few minutes. At the same time it offers a long-term protection ensuring a well preserved finished product.

Key benefits of parmetol® MBX: • Only one dose of parmetol® MBX at the very beginning of the production process is necessary to prevent or to minimise the effect of contamination during the whole manufacturing process. • parmetol® MBX provides safer manufacturing procedures and provides the opportunity to eliminate quarantine time, product recalls and downtime issues; reduces blocking of filling lines by contaminated products. • parmetol® MBX allows for sustainable use of raw materials due to low use concentrations. • As a result, parmetol® MBX complies with the standards of various ecolabels. • No H317-/EU H208-labelling of products containing < 2 % / < 0.2 % (from 6/2015) of parmetol® MBX. ** Always consider importance of good housekeeping. Ask for MQM by schülke.

Methylisothiazolone (MIT)

N–CH3S

OC4H5NOS115.15 g/mol

CAS name: 2-methyl-2H-isothiazol-3-one

CAS no.: 2682-20-4

INCI name: Methylisothiazolinone

EINECS name: 2-methyl-2H-isothiazol-3-one

EINECS no.: 220-239-6

Benzisothiazolone (BIT)

NHS

OC7H5NOS151.18 g/mol

CAS name: 1,2-benzisothiazol-3(2H)-one

CAS no.: 2634-33-5

INCI name: Benzisothiazolinone

EINECS name: 1,2-benzisothiazol-3(2H)-one

EINECS no.: 220-120-9

Composition

Laurylamine Dipropylenediamine (BDA)

NH2

N CH3H2N

C18H41N3299 g/mol

CAS name: N-3-Aminopropyl-N-dodecyl-1,3-propanediamine

CAS no.: 2372-82-9

INCI name: Laurylamine Dipropylenediamine

EINECS name: N-(3-Aminopropyl)-N-dodecylpropane-1,3-diamine

EINECS no.: 219-145-8

* Biocidal Products Regulation 528/2012

parmetol® MBX

3

parmetol® MBX-ConceptThere are various sources of microbial contamination in a manufacturing process: stagnant water in pipes may contain bacterial counts >106 cfu/ml. In addition serious sources of contamination are raw materials or other subsequently added components. What is the common approach for these problems? A single “quick-killer” is used to treat the contaminated process water and raw materials. In most cases the in-can preservative to ensure a long-term preservation is added within the last production step of the product.

schülke’s new parmetol® MBX-Concept requires the addition of the whole biocide concentration at the very beginning of the production process. Enabled due to the outstanding stability and short-term efficacy, parmetol® MBX guarantees for:

• A highly effective biocide for pre-contaminated process water • A security buffer for contaminated raw materials • Long-term in-can preservation ➜ All in one single product!

Test results comparison: parmetol® MBX | MIT/BIT | DBNPA Fast-acting biocides, so called “quick-killer” are common within several applications, e.g. the combination of dimethylol glycol, methylchloroisothiazolone and methylisothiazolone or 2,2-Dibromo-3-nitrilopropionamide (DBNPA), to name a few. Since formaldehyde releasers and halogenated organic compounds are not accepted by all ecolabels and test magazines such as German “ÖKO-TEST”, the challenge is to develop a fast-acting preservative with long-term protection based on widely accepted ingredients. Due to extensive research work, laurylamine dipropylenediamine (BDA) was recognised as an excellent synergistic molecule for today’s standard soft preservatives based on methylisothiazolone (MIT) in combination with benzisothiazolone (BIT).

Test conditions Dilutions of three preservatives containing different concentrations of either DBNPA, MIT/BIT or parmetol® MBX were prepared using sterile hard water (according to the European standard for testing chemical disinfectants and antiseptics) and inoculated with standard microorganisms (approx. 105 cfu/ml). The dilutions were streaked onto tryptone soya agar (bacteria) or sabouraud-dextrose agar (fungi) after 30 seconds 2, 5, 10 and 60 minutes. The evalua-tion was made on the basis of semi-quantitative assessment of the microbial growth of the streaks.

Results Within the test period of 60 minutes the conventional mixture of methylisothiazolone with benzisothiazolone (MIT/BIT) showed no efficacy even in high use concentrations. Whereas parmetol® MBX killed all microbes within 5 to 10 minutes accordingly performed much faster than the widely known and extensively used DBNPA.

parmetol®

MBX

mixing tank

production /application process

high/low risk of contamination

raw material(contaminated)

mixing tank

addition of raw materials / other components

finished product + in-can preservation

low risk of contamination

�lling tank

storage tanks�nished product

low risk of contamination

Candida albicans (ATCC 10231)

Staphylococcus aureus (ATCC 6538)

0 10 20 30 40 50 60

107

106

105

104

103

102

101

cfu

/ ml

contact time [min]

0 10 20 30 40 50 60

107

106

105

104

103

102

101

cfu

/ ml

0.1 % parmetol® MBX.......27 ppm BDA + 50 ppm MIT/BIT active content

0.5 % MIT/BIT ....................................................................250 ppm active content

0.04 % DBNPA .................................................................... 80 ppm active content

contact time [min]

parmetol® MBX

4

Polymer dispersion based products (e.g. paints & coatings) - Repeated challenge tests (schülke FaKo test) The test is performed to determine the efficacy of chemical preservatives, e.g. in water-containing coatings, adhesives and other water-containing technical emulsions or dispersions. This test is similar to the HauHaKo test, except 50g test batches and the current germ load is 0.2 ml with a titre of 1010 cfu/ml. A sample is considered to be well preserved after passing a period of six weeks under the above described laboratory conditions without showing microbial growth in the test batches. This means that even after the sixth inoculation no microbial contamination is observed. From experience we can state that this test equates to a microbiological stability of 24 months.

As to further improve the overall performance of parmetol® MBX various fungicides e.g. IPBC (Iodopropynyl butylcarbamate) can be added in small amounts.

Legend:

0 = sterility control - = free of microbial growthB = bacteria + = slight growthY = yeast ++ = moderate growthM = mould +++ = massive growth./. = test cancelled due to massive growth

Cleanerwith milk powder

Inoculation Cycles

0 1 2 3 4 5 6

1 unpreserved –+++B, Y, M

+++B, Y, M

./.

20.10 % MIT/BIT (2.5/2.5 %)

–++B

+++B

+++B

./.

30.20 % MIT/BIT (2.5/2.5 %)

–+B

+++B

+++B

./.

40.10 % parmetol® MBX

–+B

+B

+B

++B

++B

++B

50.20 % parmetol® MBX

– – – – – – –

HauHaKo test

Legend:

0 = sterility control - = free of microbial growthB = bacteria + = slight growthY = yeast ++ = moderate growthM = mould +++ = massive growth./. = test cancelled due to massive growth

Dispersion paintInoculation Cycles

0 1 2 3 4 5 6

1 unpreserved – –+++B, Y, M

+++B, Y, M

./.

20.10 % MIT/BIT (2.5/2.5 %)

– – –+++B, Y, M

+++B, Y, M

./.

30.15 % MIT/BIT (2.5/2.5 %)

– – –+

B, Y+

B, Y++B, Y

++B, Y

40.10 % parmetol® MBX

– – – – –+B

+B

50.15 % parmetol® MBX

– – – – – – –

6

0.05 % parmetol® MBX + 0.0025 % IPBC

– – – – – – –

FaKo test

In-can preservation properties

Household products - Repeated challenge tests (schülke HauHaKo test) The test is performed to determine the efficacy of chemical preservatives in household formulations, e. g. fabric softener, washing-up liquids, all-purpose cleaner etc. In separated batches different concentrations of the test preservatives are added to the unpreserved samples, an unpreserved sample is tested as a growth control. Two days after incorporation of the preservatives the 25g test batches are inoculated with a current germ load (0.1 ml, titre 108 – 109 cfu/ml) and obtained by a weekly inoculation of the test batches.

A sample is considered to be well preserved after passing a period of six weeks under the above described laboratory conditions without showing microbial growth in the test batches. This means that even after the sixth inoculation no microbial contamination is observed. From experience we can state that this test equates to a microbiological stability of 30 months which is recommended for finished household products.

parmetol® MBX

5

Preservation properties of metal working fluids

One of the biggest threats for quality assurance, work and process

safety in the mass production of metal parts is microbial contamina-

tion. When choosing a suitable preservative for a metal working fluid

there are various factors to consider: different ingredients, pH value,

compatibility, legal approvals and climate conditions – to name a few.

The large number of possible microorganisms cannot be covered by

just one microbial active used at an acceptable dosage.

schülke offers the metalworking industry a complete range of

tailor-made biocides for all possible applications; such as preserva-

tion of metalworking fluid concentrates, post treatment of water

mixed metalworking fluids as well as microbiocidal system cleaners.

parmetol® MBX is an optimal formulation since it offers a

formaldehyde-free solution for the upcoming requirements

with additional beneficial characteristics:

• Very fast acting, broad spectrum microbicide

• Inhibition of proliferation of aerobic/anaerobic

microorganisms in aqueous systems

• Better performance compared to CMIT/MIT as

post-treatment additive

• Enhanced efficacy with fungicides tested (e.g. IPBC, OIT or BuBIT)

Stabilisation*parmetol® MBX contains methylisothiazolone and benzisothiazolone, actives that by experience react with alkanolamines. Therefore certain stabilization is required for the use of parmetol® MBX in metal working fluid concentrates containing high amine quantities. By adding inorganic salts like potassium iodate in a ratio of 1:100 (1 part of potassium iodate stabilizes 100 parts of MIT and 100 parts of BIT in the presence of 5 % alkanolamine) the stability of parmetol® MBX is proven under following conditions: 40 °C, 12 weeks storage test.

Repeated challenge tests - Water-diluted metal working fluids (schülke BoKo test) With this method the efficacy of chemical preservatives is tested according to the preservation of water-diluted metal working fluids. In separated batches different concentrations of the test preservatives are added to the unpreserved samples. An unpreserved sample is tested as a growth control. Two days after incorporation of the preservatives the test batches are inoculated with 1 ml of an inoculation solution for the first time. This solution contains microorganisms as mentioned in the following. The titre of the solution should be approx. 109 germs/ml (≈109 bacteria/ml, ≈108 yeast/ml, ≈107 moulds/ml).

As to further improve the overall performance of parmetol® MBX various fungicides e.g. IPBC (Iodopropynyl butylcarbamate) can be added in small amounts. Additionally it was found that Phenoxyethanol or -propanol are supportive as well and could be an interesting solvent for your metal working fluids if parmetol® MBX is used!

* Test design: 5 % monoethanolamine, 3 % parmetol® MBX, 0.05 % potassium iodate

Legend: 0 = sterility controlB = bacteriaY = yeastM = mould

- = free of microbial growth+ = slight growth++ = moderate growth+++= massive growth./. = test cancelled due to massive growth

BoKo test

BoKo Test SM 019 Weekly inoculation with1010 cfu/ml (inoculum)

Inoculation Cycles

0 1 2 3 4 5 6 7 8 9 10 11 12

15 % of coolant in tap water, unpreserved

–+++

B, Y, M+++

B, Y, M+++

B, Y, M./.

2 0.10 % parmetol® MBX –+++B, Y

+++Y

+++Y

./.

3 0.20 % parmetol® MBX – – – – – – – – – – – – –

4 0.30 % parmetol® MBX – – – – – – – – – – – – –

50.10 % parmetol® MBX+ 0.0025 % IPBC

– – – – – – – – – – – – –

parmetol® MBX

Approvals | Compliance Max. concentration parmetol® MBX

RAL UZ (Blue Angel conformity) 102 and 113 0.3 %

BfR (Recommendation on indirect food contact XIV and XXXVI)

Recommended max. use concentration 0.3 %

IKEA (Positiv list biocides IOS-MAT-066) 0.98 %

Ion exchanger compatibility (24 h test trial, 50 °C)

Proven for a concentration up to 0.3 %

Indications for useGeneral remarksparmetol® MBX is a water soluble, light yellow to orange liquid with a characteristic odour.

InventoryTSCA | DSL | PICCS | AICS | IECSC | NZIoC | CSNN | EINECS

Stability aspectsTo test the functionality of parmetol® MBX under different circumstances, several stability tests were carried out: • parmetol® MBX shows outstanding pH- and temperature stability. • Possibility to stabilise parmetol® MBX in the presence of primary (e.g. 2-aminoethanol (MEA)) and tertiary (e.g. Triethanolamine (TEA)) amines.

6

Ecolabel Household

Basic criteria Product typeMax. use concentration

European Flower

2011/264/EC laundry detergents 0.37 %

European Flower

2011/382/EChand dishwashing detergents

0.2 %

European Flower

2011/383/ECall-purpose cleaners and cleaners for sanitary facilities

0.2 %

Nordic Ecolabel

Nordic Swan*Cleaning Products Version 5.2

0.4 %

Ecolabel Paints and Coatings

Basic criteria Product typeMax. use concentration

European Flower

2014/312/ECindoor paints and varnishes

0,8 %

Nordic Ecolabel

Nordic Swan**indoor paints and varnishes

1,0 %

Nordic Ecolabel

Nordic Swan**outdoor paints and varnishes

1,0 %

Nordic Ecolabel

Nordic Swan** fillers 1,0 %

Nordic Ecolabel

Nordic Swan** adhesives 0,2 %

Nordic Ecolabel

Nordic Swan** sealants 0,2 %

Technical properties

pH-range for application 3 - 10

Max. manufacturing temperature 80 °C

Physical-chemical data

Colour light yellow - orange

Form liquid

Odour characteristic

Density (20 °C) 1.009-1.021 g/cm3

Refractive index 1.345 -1.357

Initial boiling point ca. 100 °C

Flash point (ISO 2719) > 100 °C

Flow time (DIN 53211, 20 °C) < 15 s

Water solubility (20 °C) in all proportions

VOC Content to Directive 2004/42/EC none

pH (concentrate) approx. 8 - 9

Use concentrations

Household products 0.05 – 0.4 %

Wet wipes 0.05 – 0.2 %

Paints and coatings 0.1 – 0.4 %

Adhesives 0.1 – 0.4 %

Polymer dispersions 0.1 – 0.4 %

Metalworking (emulsion) 0.1 – 0.4 %

Legionella pneumophila efficacy ≥0.1 %

Use biocides safely. Always read the label and product information before use.

At schülke, we continually strive to make our products globally available. However, due to various factors, the availability of our products in your area may not always be guaranteed. Please contact us at sai@schuelke.com for more information on our product range in your country.

* Not for aerosol products

** Chemical Building Products Version 2.1

parmetol® MBX

7

Material compatibilityConcentrateIn the material compatibility tests with the concentrate of parmetol® MBX high-alloyed stainless steel (e. g. 1.4571), steel, nitrile rubber, fluorinated rubber, natural rubber, polyethylene, polyvinylchloride (hard) and polystyrene proved to be suitable materials for handling the undiluted product. Copper, brass, zinc, sealants and plastics other than mentioned should not be used.

DilutionsThe behaviour of parmetol® MBX in 0.2 % aqueous solution with regard to material compatibility of metals and plastics was not significantly different from that of tap water. A slight incompatibility with brass was determined.

StorageStore in original container. Keep away from frost, heat and direct sunlight. Limited stability - see label on pack.

SanitisationNext to preservation and system cleaning schülke’s MQM concept requires additional sanitization products as to prevent contamination or clean-up contaminated rinse and cleaning water. Therefore parmetol® MBX is highly recommended since a quick sanitization effect is possible with this product. Use solutions can be stored several months.

Use | use concentrations:• Production plants and circulating systems: 0.5 % in aqueous solutions of parmetol® MBX

grotanol® FF 1 NEnsuring reliable product quality also requires a regular cleaning and microbiological sanitation of the production plant. grotanol® FF 1 N is a formaldehyde-free waterbased system cleaner which provides a good immediate effect at a low use concentration in combination with mechanical cleaning. grotanol® FF 1 N is based on benzisothiazolone (BIT), laurylamine dipropylenediamine (BDA) and sodium pyrithione.

Product benefits:• Innovative surfactant system• Outstanding (biocidal) cleaning properties• Broad spectrum efficacy against bacteria, yeasts and moulds - fulfills DIN EN 1650 and 1276• Free of formaldehyde and halogenes

Use | use concentrations:• Production plants, circulating systems and equipment: 1 – 3 % in aqueous solutions

grotan® BA 21If a MIT-free product is required grotan® BA 21 can be your solution. Having formulated BIT and BDA as two synergists only grotan® BA 21 offers a performance close to parmetol® MBX. This alternative can be applied according to the outlined parmetol® MBX-Concept and easily be formulated with all common fungicides in use. For further information please contact us directly! Product benefits:• Broad, balanced spectrum of effect against bacteria, yeasts and moulds • Enhanced efficacy especially against pseudomonas sp. • Free of chloromethylisothiazolone, methylisothiazolone, formaldehyde, formaldehyde depots and other aldehydes • Effective even in very low use-concentrations • Also applicable according to the parmetol® MBX-Concept

Use | use concentrations:• Technical formulations: 0.05 – 0.2 %

What´s beyond:

MQMWe are convinced that controlled and responsible use of disinfectants and preservatives is the only way to ensure the sustainable protection of man, materials and the environment. schülke not only manufactures preservatives and disinfectants but also offers Microbiological Quality Management as a holistic approach to achieve hygienically-sound products. On request we can conduct a thorough Hygiene Audit of your operation, train your staff in hygiene practices, provide advice on factory design and compile detailed hygiene plans for your organisation. If you are interested in taking a comprehensive approach to preventing microbiological contamination and safeguarding your products and processes then we will be pleased to support you.

Shelf life18 months at recommended storage conditions. Product specification is valid for the whole shelf life.

Environmental informationparmetol® MBX contains only biodegradable components. Dilutions of parmetol® MBX do not normally interfere with the operation of waste water treatment plants. schülke has DIN EN ISO 9001 and EN ISO 14001 certification and has a validated environmental management system in accordance with the Eco Audit Regulation (Reg. No. D-150-00003). The canisters and drums used by schülke are made of polyethylene (HDPE) and are labelled accordingly. The 1000 kg containers are affiliated to a recycling system that guarantees free pick-up and sen-sible utilisation of used containers throughout Europe. The labels are made of polyethylene (PE). Our packaging materials contain no PVC and are recyclable. Samples of our products are supplied together with extensive information and are supported by personal advice.

Industrial property rightsparmetol® MBX is covered by protective rights.

For more information visit our website: www.parmetol-MBX.com

SAI -T

|GB|

03.16

Our recommendations regarding our products are based on in-depth scientific testing in our Research Department; they are given in good faith, but no liability can be derived from them. It is the responsibility of the final product manufacturer to assure that claims made for the final product are in conformance with all applicable local laws. In other respect our Conditions of Sale and Supply apply.

Schülke&Mayr GmbH22840 Norderstedt | GermanyPhone | Fax +49 40 521 00- 0 | -244www.schuelke.com | sai@schuelke.com

A company of the Air Liquide Group

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schülke worldwide:

ChinaSchülke & Mayr GmbHShanghai Representative OfficeShanghai 200041Phone +86-21-62 17 29 95Fax +86-21-62 17 29 97mail.cn@schuelke-mayr.com

FranceSchülke France SARL92800 Puteaux, Paris La DéfensePhone +33-1- 42 91 42 42Fax +33-1- 42 91 42 88schuelkefrance.info@schuelke.com

United KingdomSchülke & Mayr UK Ltd.Sheffield S9 1ATPhone +44-114-254 35 00Fax +44-114-254 35 01mail.uk@schuelke.com

ItalySchülke & Mayr Italia S.r.l.20158 MilanoPhone +39-02-40 26 590Fax +39-02-40 26 609info-italia@schuelke.com

BeneluxSchülke & Mayr Benelux B.V.2031 CC HaarlemPhone +31-23-535 26 34Fax +31-23-536 79 70salesbenelux@schuelke.com

SwitzerlandSchülke & Mayr AG8003 ZurichPhone +41-44-466 55 44Fax +41-44-466 55 33mail.ch@schuelke-mayr.com

TurkeySchülke & Mayr GmbHKavacik, 34805 Beykoz, IstanbulPhone +90-216-331-39-66Fax +90-216-331-39-36

USA schülke inc.Fairfield, NJ 07004Phone +1-973-770-7300Fax +1-973-770-7302saius@schuelke.com

2615 | IV | 04.16 | C | Rako This information is not automatically updated.