Partnerships  on  the  Path  to  Commercializa2on  of  DDDA  

Tom  Beardslee,  PhD  

ABLC  Next  Conference,  San  Francisco  CA  November  11,  2014  

10x Scale Up 40x Scale Up 6x Scale Up

Proof of Concept Lab Validation Pilot Small Commercial

25,000 L

400 L 10 L

1 L

•  Functional pathway for production of target

•  Measureable outputs

•  Design fermentation process

•  Commercially relevant yield (50% of maximum)

•  Process optimization •  Demo process at scale •  Proof of concept •  Produce market samples

•  Data to construct commercial facility

•  Establish offtake

4,000 L

10x Scale Up

Demonstration •  Confirm process •  Scale up samples •  Reduce scale-up risk

“The  Path  to  Commercializa2on”  

Fermenta2on-­‐based  Technology  PlaJorm  

Feedstock  Strategy   Proprietary  Technology   Chemical  Intermediates   End-­‐Products    

•  Vegetable  oils  •  Soapstocks  and  dis2llates  •  Other  palm  co-­‐products  (i.e.  PKO,  PFAD)  

Robust  yeast  pla-orm  using  industrial  

fermenta5on  methods   Total  $70B+  Market  

•  Nylon  and  polyesters  •  Fibers  •  Polyurethanes  •  Engineered  Plas2cs  •  Lubricants  •  Coa2ngs  &  adhesives  •  Corrosion  Inhibitors  •  Transparent  

Thermoplas2cs  

Total  $1.5T+  Market  

Using  faCy  acids  from  any  source  to  produce  

chemicals  

•  Organisms  engineered  for  yield  and  selec2vity  

•  Fermenta2on-­‐based  produc2on  

•  Diacids  used  in  fibers,  polymers  and  coa2ngs  

•  Other  organic  acids  •  Acrylic  intermediates  

Merging  Value  Chains  by  Diversifica2on  &  Differen2a2on  

Crude  Vegetable  Oils  

Crude  Oil  &  

Natural  Gas  

Standard  Conversions  

•  Edible  Oils  •  Oleochemicals  

-­‐  FaZy  acids  -­‐  FaZy  alcohols  

•  Biodiesel  

Petrochemical  Refining  

•  Petrochemical  Intermediates  -­‐  Adipic  Acid  -­‐  Sebacic  Acid  -­‐  DDDA  

Verdezyne  Technology  

Global  Produc2on  of  Vegetable  Oils  

Data  from  USDA  Foreign  Agricultural  Service's  Produc5on,  Supply  and  Distribu5on  (PSD)  Database,  2013/2014  data  presented  

5  

10  

25  

Million  Tons   Palm    

Soybean    

Rapeseed    

Sunflowerseed    

Partnerships  De-­‐risking  Commercializa2on  

25,000 L

400 L 10 L

1 L

4,000 L

Construc2on  of  Commercial  Bio-­‐DDDA  Facility  

•  Beginning  construc2on  early  Q2  2015    

•  30  million  pound  /  year  capacity  (13.6  kt/yr)  

•  Commercial  produc2on  to  begin  in  2017  

Thank  You!  

Verdezyne,  Inc.  2715  Loker  Avenue  West  Carlsbad,  CA  92010  

www.verdezyne.com  760.707.5245