pathology mcq
DESCRIPTION
Pathology MCQ. PHASE 1. 1.Which of the following appear in the red cells of Ivemark syndrome/ asplenic individuals? Macroovalocytosis Basophilic stippling Howell-Jolly bodies Target cells. 2. The life span of platelets in circulation is about? a. 1 to 3 days b.3 to 5 days - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/1.jpg)
Pathology MCQ
PHASE 1
![Page 2: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/2.jpg)
1.Which of the following appear in the red cells of Ivemark syndrome/asplenic individuals?
a. Macroovalocytosis b.Basophilic stipplingc. Howell-Jolly bodiesd.Target cells
![Page 3: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/3.jpg)
2. The life span of platelets in circulation is about?
a. 1 to 3 days b.3 to 5 days c. 5 to 7 days d. 7 to 10 days
![Page 4: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/4.jpg)
3. A 13 yr old child suffered from dysentery one week ago, currently complaining of hematuria and raised serum creatinine. PBS examination is expected to show:
a. Target cellb.Spherocyte c. Schistocyte d.Bite cell
![Page 5: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/5.jpg)
4. HbC is best illustrated as?
a. Α2ß2 3Glu→Lys
b. Α2ß2 4Glu→Lys
c. Α2ß2 5Glu→Lys
d. Α2ß2 6Glu→Lys
![Page 6: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/6.jpg)
5. The 4T ‘s scoring system for pre-test probability of HIT includes all except:
a. Thrombocytopenia b. Timing of platelet count fallc. Thrombosisd. Treatment dose
![Page 7: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/7.jpg)
6.In comparison to myeloma,which is more frequent in plasma cell leukemia:
a. Osteolytic lesionb.Bone painc. Renal failured.All of the above
![Page 8: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/8.jpg)
7. Leukaemia with t(15;17)(q22;q12) usually has the immunophenotype:
a. CD13,CD33,CD15,CD117b.CD13,CD33,CD117,HLADRc. CD13,CD33,CD117,cMPOd.CD13,CD33,CD15,cMPO
![Page 9: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/9.jpg)
8. Match the following with respect to iron deficiency
anaemia:
a. Red cell zinc protoporphyrin (ZPP)
b. Serum transferrin receptor
c. Transferrin saturationd. Hepcidin
1. Increases
2. Decreases
3. Increases 4. Decreases
![Page 10: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/10.jpg)
9. Which of the following is safe in therapeutic doses in patients with G6PD deficiency:
a. Primaquineb.Acetaminophenc. Sulfamethoxazoled.Dapsone
![Page 11: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/11.jpg)
10. The affinity of haemoglobin for Oxygen is decreased by all except:
a. Fever b.Alkalosisc. Binding of CO2d.Binding of 2,3-DPG
![Page 12: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/12.jpg)
11. An Increased percentage of HbA2 is expected in :
a. αthal traitb. ßthal traitc. δßthal traitd. All of the above
![Page 13: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/13.jpg)
12. A 15 yr old child presents with fever and generalised petechiae, lab investigation reveal:
• Hb 6gm% MCV = 105fl MCH = 30pg • WBC = 1.2 X 109 /L PC = 10 X 109 /L • LYMP%- 73%, GRAN%-25%,MID%-2%• BM: Hypo cellular. What is the most likely diagnosis?a. Severe aplastic anemiab. Very severe aplastic anemiac. Nonsevere aplastic anemiad. Hypoplastic MDS
![Page 14: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/14.jpg)
13. All are direct thrombin inhibitors except:a. Fondaparinux sodiumb.Bivalirudinc. Argatroband.Lepirudin
![Page 15: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/15.jpg)
14. For the given coagulation work up results which is the most probable diagnosis:
• BT- 5 min• PT- 11 sec ( 10 sec)• APTT- 50sec (32 sec)• Mixing study with factor IX deficient plasma: APTT – 40
seca. Hemophilia Ab. Hemophilia Bc. Hemophilia Cd. Factor VIII inhibitor positive
![Page 16: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/16.jpg)
15. Regarding febrile nonhemolytic transfusion reaction false is:
a. More common in multiply transfused patientsb.HLA antibodies are most commonc. Leucodepletion of blood products is not
helpfuld.Due to transfusion of cytokines
![Page 17: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/17.jpg)
16. Which is not a GpIIb/IIIa inhibitor:a. Abciximabb.Eptifibatidec. Tirofiband.Argatroban
![Page 18: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/18.jpg)
17.Haemolytic disease of new born(erythroblastosis fetalis ) is an example of:
a. Type I hypersenstivityb.Type II hypersenstivityc. Type III hypersenstivityd.Type IV hypersenstivity
![Page 19: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/19.jpg)
18. Pre-transfusion cross-match is not required for:
a. Cryoprecipitateb.pRBCc. FFPd.Granulocyte tranfusion
![Page 20: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/20.jpg)
19. Neutrophilia is seen in all except:a. Leucocyte adhesion defectb.Steroid administrationc. Lithium therapyd.Kostmann syndrome
![Page 21: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/21.jpg)
20. Infectious complications of blood transfusion may result from all except:
a. HTLV Ib.HTLV IIc. West Nile virus d.None of the above
![Page 22: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/22.jpg)
21. Good prognosis ALL:a. t(4;11)b.t(9;22)c. t(12;21)d.t(1;19)
![Page 23: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/23.jpg)
22. For diagnosis of Smoldering Myeloma, false is:
a. BM plasma cells ≤ 10%b.Absence of anemiac. Serum monoclonal protein ≥ 3g/dld.None of the above
![Page 24: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/24.jpg)
23. IPSS for MDS includes all except:a. Marrow blast %b.Karyotype c. Cytopeniasd.Age
![Page 25: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/25.jpg)
24. Hairy cell leukaemia , immunophenotype:a. Bright CD20,CD10,CD25,CD103b.Dim CD20,CD10,CD25,CD103c. Bright CD20,CD11c,CD25,CD103d.Dim CD20,CD11c,CD25,CD103
![Page 26: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/26.jpg)
25. WHO definition of anaemia in pregnancy requires Hb below:
a. 10g%b.11g%c. 12g%d.13g%
![Page 27: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/27.jpg)
26. Albino child with repeated infection
most probable diagnosis:a. Grescilli syndromeb. Chediac Higashi syndromec. Dohle bodiesd. Toxic granules
![Page 28: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/28.jpg)
27.
Comment on PBS:
![Page 29: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/29.jpg)
28.
Identify the cell with arrow head:a.Gaucher cellb.Mott cellc.Histoplasma inclusion d.Fungal bodies
![Page 30: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/30.jpg)
29.
Identify the abnormality in the Karyotype
![Page 31: Pathology MCQ](https://reader030.vdocument.in/reader030/viewer/2022012307/56813253550346895d98d32a/html5/thumbnails/31.jpg)
30.Identify the cytogenetic finding shown in the FISH metaphase spread.