patient specific qc in aarhus

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Patient specific QC in Aarhus Lone Hoffmann Ulrik Vindelev Elstrøm, Mai-Britt Kyed Jørgensen

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Patient specific QC in Aarhus. Lone Hoffmann Ulrik Vindelev Elstrøm, Mai-Britt Kyed Jørgensen. VMAT introduction. Introduced in May 2009 First patient: June the 17th, 2009 Treated approx. 800 patients Primarily pelvic cancers Prostate, cervix, bladder, anal, rectum,.. Other types: - PowerPoint PPT Presentation

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Page 1: Patient specific QC in Aarhus

Patient specific QC in Aarhus

Lone HoffmannUlrik Vindelev Elstrøm, Mai-Britt Kyed Jørgensen

Page 2: Patient specific QC in Aarhus

VMAT introduction

Introduced in May 2009 First patient: June the 17th, 2009 Treated approx. 800 patients Primarily pelvic cancers

Prostate, cervix, bladder, anal, rectum,..

Other types: Brain, sarcomas, abdominal

Page 3: Patient specific QC in Aarhus

Patient specific QA

Perform Delta4 verification for all patients Normalization to daily output Gamma(3,3) > 95 % Most patients: G(3,3) > 97 %

Page 4: Patient specific QC in Aarhus

Test/learning plans

10 prostate plans (15MV)were created with: 250MU, 500MU, 750Mu, 1000MU, 2000MU In 1 or 2 arcs

10 H&N plans (6MV) were created with: 250MU, 500MU, 750Mu, 1000MU, 2000MU In 1 or 2 arcs

2 Gy/fx

Page 5: Patient specific QC in Aarhus

G(3,3) vs. #MUs G(3,3) decreases as a function of MUs Planning criteria: MU < 400 for 1/2 arcs

Page 6: Patient specific QC in Aarhus

G(3,3) vs. accelerator

Differences between accelerators

Page 7: Patient specific QC in Aarhus

Test plans used for QA 6 of the test plans are use for QA 4 times a year each acc. Plans with high G(3,3) are very stable (within 2-4%)

acc7

80

85

90

95

100

06-07-2009

22-01-2010

10-08-2010

26-02-2011

14-09-2011

01-04-2012

Prost1 250Tonsil1 250Prost2 500Tonsil2 500Prost1 2000Tonsil1 2000 Low/moderate modulation

High modulation

Page 8: Patient specific QC in Aarhus

Test plans used for QA

Some accelerators are more stable than others Acc1 performs bad in autumn 2011 – no

problems with mashine QC

Test_RI_Prost2, 15MV, 500MU, Gamma(3,3)

90

91

92

93

94

95

96

97

98

99

100

06-07-2009

14-10-2009

22-01-2010

02-05-2010

10-08-2010

18-11-2010

26-02-2011

06-06-2011

14-09-2011

23-12-2011

01-04-2012

Acc 2

Acc 5

Acc 6

Acc 9

Acc 3

Test_RI_Prost2, 15MV, 500MU, Gamma(3,3)

90

91

92

93

94

95

96

97

98

99

100

06-07-2009

14-10-2009

22-01-2010

02-05-2010

10-08-2010

18-11-2010

26-02-2011

06-06-2011

14-09-2011

23-12-2011

01-04-2012

Acc 1

Acc 4

Acc 7

Acc 10

Acc 8

Page 9: Patient specific QC in Aarhus

Acc QC vs. Patient spec QC

Problems with acc QC on acc 5 (spring 2011) Not seen for patient specific QC

-0.2

0

0.2

0.4

0.6

0.8

1

1.2

1.4

1.6

0 100 200 300 400 500 600 700

Pixel

No

rm

Leaf 30 Leaf 30 baggrund

Acc5 Gamma(3,3)

90

91

92

93

94

95

96

97

98

99

100

06-07-2009

14-10-2009

22-01-2010

02-05-2010

10-08-2010

18-11-2010

26-02-2011

06-06-2011

14-09-2011

23-12-2011

Prost2 500

Tonsil2 500

Prost1 250

Tonsil1 250

Low dose rate

DRMLC test

Page 10: Patient specific QC in Aarhus

86

88

90

92

94

96

98

100

0 5 10 15 20 25

Different patients

G(3

,3)

Acc 4 08-04-2010Acc 6 08-09-2010Acc4 08-17-2010Acc 4 08-18-2010Acc 6 08-19-2010Acc 8 08-23-2010Acc 8 08-25-2010Acc10 09-02-2010Acc3 10-14-2010Acc 6 11-11-2010

Real patient plans Reproducibility for each acc Difference between acc – not seen with acc QC

acc3

Page 11: Patient specific QC in Aarhus

True beam

5 patients treated at Clinac and True beam G(3,3) does not depend on Clinac/True beam?

MeanG(Clinac)=98.4% MeanG(TrueBeam)=99.0%

Page 12: Patient specific QC in Aarhus

Portal dosimetry Use EPID/MVD for patient specific QC Fast measurement Ideal for routine measurements

Page 13: Patient specific QC in Aarhus

127 Single arcs G(3,3)

80,0

85,0

90,0

95,0

100,0

80,0 85,0 90,0 95,0 100,0

Delta4

PD

I

Single arcs G(3,3) Unity Composite G(3,3)

Delta4 vs. PDI Perform Delta4 and PDI measurement consecutively at

same accelerator Preliminary results, Oct-Dec 2011:

68 plans (1,2, ..6 arcs) 127 single arcs

Single arcs G(3,3)D4: 1.7% higher than G(3,3)PDI

Plans G(3,3)D4: 1.0% higher than G(3,3)PDI

Pass criteria: G(3,3)D4: 95% G(3,3)PDI: 94%

Page 14: Patient specific QC in Aarhus

Work in Progress Measurement of D4 and PDI for same plan at

different accelerators Analysis of data (approx 100 plans and 10 new

plans pr week) Workflow today:

Daily PDI; used for accept/reject Weekly D4; used for check

Future: Only PDI New/additional machine QC program

Page 15: Patient specific QC in Aarhus

Machine QC program

MV imager:Test of ”clinical” dose ratesTest of reverse gantry direction

Test of gantry position Delta4

Still of measurement of 6 test plans 4xyear each accelerator