vanessa a. sanders - university of nevada, las vegas a. sanders is a 5th year student in the unlv...
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Vanessa A. Sanders Office: HRC 205 Mail code: 4009 Phone: (321) 536-3540 Fax: (702) 895-3094 Email: [email protected]
Biography Vanessa A. Sanders is a 5th year student in the UNLV Radiochemistry PhD Program. She received her Bachelor of Arts in Chemistry from Florida Memorial University. Research The Characterization and Crystallization of Re/
99Tc-complexes for Radiopharmaceuticals
Radiopharmaceuticals are very powerful diagnostic tools for evaluation a host of medical conditions. The radioisotope
99mTc is central to many of these
compounds. Understanding and exploiting technetium chemistry can provide insight into the reaction mechanisms and coordination chemistry of these compounds. Ligands are chosen based on their in-situ biological behavior. The KYCAR (lysyl-tyrosyl-cystyl-alanyl-arginine), ligand has been designed for the possible application for tumor imaging for breast cancer. The coordination chemistry and reaction mechanisms must be efficiently characterized to ensure the reproducibility of the radiopharmaceutical. The current study focuses on pentapeptide macrocyclic ligands and their interactions with radioactive elements. The exploration of various oxidation states as a function of the ligands used and the reaction conditions can help develop novel radiopharmaceuticals. Complexes will be characterized by UV-Visible Spectroscopy, NMR, Electrospray Ionization Mass Spectroscopy, Single-crystal XRD, and XAFS, to compare them to current radiopharmaceuticals. Publications, Presentations and Awards The Characterization of
Re/
99Tc-Complexes for Radiopharmaceuticals
17th
Radiochemical Conference Marianske Lazne, Czech Republic 2014 The Characterization of
Re/
99Tc-Complexes for Radiopharmaceuticals
243rd
ACS National Meeting & Expo Indianapolis, Indiana 2013
The Characterization of Re/
99Tc-Complexes for Radiopharmaceuticals
ANS Student Conference Atlanta, Georgia 2011 The Characterization and Crystallization of
Re/
99Tc-Complexes for Radiopharmaceuticals
242nd
ACS National Meeting & Expo Denver, Colorado 2011 The Characterization and Crystallization of
Re/
99Tc-Complexes for Radiopharmaceuticals
242nd
ACS National Meeting & Expo Denver, Colorado 2011