Pediatrics doses of commonly used drugs

BY: Ala’a Fadhel Hassan & Magedel Alshams Mahdi/clinical pharmacy

Drug Doses Amikacin 15mg/kg/day (sever sepsis 20 mg/kg req.)

Aminophylline

Loading: 5mg/kg over 20min. Maint: 0.5-0.8-1mg/kg/hr (age dependent)

Calcium gluconate Intial: 0.11 mmol/kg slow IV or inf. (o.5 ml) Maint: 1mmol/kg/day

Ceftriaxone (novocef) 20-50mg/kg/day (meningitis 80mg/kg infusion req.)

Cefotaxime (Claforan) 50mg/kg every 8-12hr (time interval dep. on age)

Ceftazidime 30-50mg/kg 2-3 times/day (time interval dep. on age) Dexamethason (decadron)

0.2-0.4mg/kg day once (as anti inflamm.) 0.15mg/kg every 12hr (for croups)

Diph.hydramin (allermin) 1-1.25mg/kg every 6hrs Furosemide (lasix) 0.5-1mg/kg/dose every 6-12hr

Gentamicin (garamycin) 5-7mg/kg/day IV inf. (septic pt.8mg/kg/day req.)

Glucose 50 % (hypertonic sol.)

Hypoglycemia 200-500mg/kg /day Hyperkalemia 500mg-1g/kg/day

Hydrocortisone 2.5mg/kg bolus then 2mg/kg every 6hr (neonates) 4mg/kg every 6hr (other ages)

KCl 20mEq 1-2mmol/day add to IVF (0.5-1mEq/kg/dose)

Meropenem 20mg/kg every 8-12hr (sever inf. 40 mg/kg/day req.).

Metoclopromide (plasil) 0.1mg/kg/day (6-14yr 2.5-5mg single dose) Metrondazole (flagyl)

7.5mg/kg every 8-12hr (loading inf. of 15mg/kg rec. in neonate)

NaHCO3 8.4% (sod.bicarb) 1-5mmol/kg single dose (1ml) Oseltamivir (tamiflu)

0-1mnth 2mg/kg twice 1-3yr 30mg twice/day 1-3mnth 2.5mg/kg twice 3-7yr 45mg twice/day 3-12mnth 3mg/kg twice 7-12yr 60mg twice/day

Ranitidine (zantac) 1-3mg/kg 3-4times daily (unlicensed adm. route)

Teicoplanin (Targocid)

10mg/kg twice(3 doses) then 6-10mg/kg once/day

Vancomycin 15mg/kg every 8-12-24hr (interval dep. on age)

Vit B6 (pyridoxine) 100mg as therap.trial (risk of cardiovascular collapse) Vit K (phytominadion) 0.4-1mg/kg single dose