Pengembangan Farmasi Veteriner

RINI AGUSTIN , M.Si,Apt

INTRODUCTION Animal provide us with companionship, recreation,

food and animal labor Just like human these animal receive medicine to

keep them healthy Drugs have been compounded for veterinary

practise for many years but regulation and compliance policy Guidelines (CPG) should be recognized

A CPG issued in July 2003 listed the current FDA limitation on compounding for veterinary medicine

Introduction Compounding can be characterized as any manipulation

to produce a dosage form other than manipulations that

is provide for in the directions for use on the labeling of

an approved drug product. This is to say that mixing a

pediatric liquid antibiotic is not compounding, but making

a sterile inject able from non-sterile materials is the most

difficult form of compounding.

Introduction Compounding should be the ultimate expression of

Pharmaceutical Care. In order to practice good

Veterinary Pharmaceutical Care the individual will

have to broaden his/her skills beyond human

pharmacology. The diversity of issues involved

with the myriad of species requiring pharmaceutical

interventions is legend.

Introduction Using the ADME model in human patients requires the practitioner to investigate each

step as a consequence of multiple pathologies, using the same model in the veterinary population requires an understanding of the species-specific anatomy, physiology, bio-chemistry, velocity of metabolism to name just a few confounds

Introduction The office based vet is a recent phenomenon. Historically

veterinarians necessarily dispensed medications from their own dispensary. Classically the vet traveled from farm to farm plying their skills which involved not only diagnostics but also creating dosage forms out of readily available materials. To this day the pharmaceutical industry pays vague lip-service to the veterinarian industry.

Introduction The research and development costs involved with

bringing a veterinary new drug to the market-place

sometimes exceed the cost of bringing the very

same drug to the human market-place. As a matter

of course, there are several exotic species with no

approved drug. This yields a very fertile field for

cultivation by an appropriately trained pharmacist.

Introduction The fundamental relationship in veterinary compounding pharmacy is the

Patient-Physician-Pharmacist triad. The addition of the owner can complicate the triad or it can facilitate providing good Pharmaceutical Care. We have seen the complications that the inter-net has created in human medicine, one can expect the same uneducated and sometimes dangerous interventions in veterinary medicine. It is the responsibility of each of us to ensure that our patients will receive the best that our profession provides to the human population

Compounding can be characterized as any manipulation to produce a

dosage form other than manipulations that is provide for in the directions for

use on the labeling of an approved drug product.

Regulation in Indonesia PERATURAN PEMERINTAH REPUBLIK INDONESIA NOMOR 78

TAHUN 1992 TENTANG OBAT HEWAN PERATURAN MENTERI PERTANIAN NOMOR

74/Permentan/OT.140/12/2007 TENTANG PENGAWASAN OBAT HEWAN

 PERATURAN MENTERI PERTANIAN NOMOR 18/Permentan/OT.140/4/2009 TENTANG SYARAT DAN TATA CARA PEMBERIAN IZIN USAHA OBAT HEWAN

PERATURAN MENTERI KESEHATAN NOMOR 466 TAHUN 1999 TENTANG CPOBH

Organisasi Terkait di Indonesia Affaveti (asosiasi Farmakologi dan

Farmasi Veteriner Indonesia) ASOHI (Asosiasi Obat Hewan Indonesia Bbpmsoh (balai besar pengujian mutu

dan sertifikasi obat hewan )

Interaction with Vets

You are the drug experts! Logic Disconnect: Who knows?

You don’t know everything, get a book

Just because you can do it, doesn’t mean you should.

Vets are really nice people

Interaction with Vets Vet Techs are the gate keeper.

Vet techs can be your best friends. Vet techs can be your worst nightmare. Vet techs want to learn. Receptionists are not Vet Techs Some Vet techs are not Vet techs Some “nurses” are vet techs, some nurses

are nurses and some nurses aren’t .

Interaction with Vets Clients are the owners, patients are the animals

SID means once a day, don’t argue you won’t win.

The pharmacological argument. Win, lose or draw.

Don’t mess it up for the rest of us

Just say No.

The Patients/Clients The patient is the animal, the client is the

owner/guardian.

Large Animals /Food Animals/ Zoo animals Probably not the best place to start.. Dr. Midnight Milk Cup The squirt gun approach

The Patients/Clients Companion Animals

You wouldn’t believe what some people have as pets. Aardvarks to zebras, really.

Gerbils, turtles, snakes, butterflies, lizards, large predator cats, elephants, ennui’s, swans, storks, flamingoes, fish, frogs, goats, pigs, foxes, hedgehogs, wolves, foxes,

The Patients/Clients Canine

There are many breeds but they are all canines. There are many genetic specific predominant. The new pocket breeds are fraught with genetic

problems Dogs eat rocks Idiopathic Canine Epilepsy Thunderstorm Phobias Dry Eye Ear Grunge

The Patients/Clients Feline

Cats are finicky, prissy, compulsive, passive aggressive.

Pilling cats ain’t fun You can trick them a couple of times, but plan on

them catching on. Mega colon Hyperthyroidism Hypertensive Psychotic

The Patients/Clients Compounded Companion Animal Dosage Forms

Tablet Triturates Flavored Liquids Treats Transdermals Flavored pastes Capsules

Resources and References Veterinary Information Network A great reference source and a place to interact with

vets. You will need to have a vet sponsor and probably will have to advertise.

http://vin.com/ Plumb’s This is the ubiquitous green book. (although it’s red now)

This is the definitive handbook on veterinary pharmaceutics. It can be accessed via VIN.

Plumb's Veterinary Drug Handbook, Fifth Edition, Donald C. Plumb

Resources and References Mc Gavin’s This is the Depiro of veterinary pharmacology. Great

basic book. The fourth edition is current. Pathologic Basis of Veterinary Disease, Fourth Edition,

Mc Gavin, Donald etal. Moby. ACVP The pre-eminent society of Veterinary Pharmacists. The

put out a newsletter on a regular basis. They also have a Dear Doc letter that can be used in marketing your practice.