ORecommendation Leads inx Medical to Permian Plastics

As a referral from an existing Permian Plastics client, inx Medical was aware of the range of services and high quality standards in the controlled environment, GMP compliant facility with ISO, FDA and UL certi�cation. inx Medical had a design developed which required engineered plastics and some �ne tuning for performance and cost e�ective tooling. The �nished Nexus™ Ligator needed to be assembled, individually packaged, sealed and kept clean under GMP standards.

Material Requirements & Functionality

Permian’s broad range of medical engineered plastics’ expertise matched the Nexus™ Ligator material requirements with the right plastic options: • Non-BPA• Recyclable• Safe. Eastman Tritan™ copolyester-industry-recognized testing for attributes such as toughness, clarity and sustainability and completion of numerous tough safety tests.The dual triggers in the handle were color coded by use. The trigger material was selected for lubricity, designed to provide the physician smooth, comfortable control.

When asked about the overall experience with Permian Plastics, Jim Vermeersch, President & CEO inx Medical, responded “Permian’s support was timely and professional. They were very responsive and a pleasure to work with, while further developing the Nexus™ Ligator. I would have no reservations recommending the team at Permian Plastics.”

Nexus™ Ligator with Easy Fire™ technologyImproving the non-surgical treatment for hemorrhoids.

OOPTIONS Material Selection Key to Product Success

Permian PlasticsMedical Device Case Study

inx Medical envisioned a medical device for the treatment of hemorrhoids that would deliver signi�cant advantages to the patient and physician over devices which are currently being used.

Patient Advantages - time and discomfort reduced!• Rubber band ligation in less than 5 minutes without anesthesia or pain medication • Average recovery time less than 1 day• Average success rate of 95%

Physician Advantages - an opportunity for expanding their continuum of care, while providing a safe and painless experience for hemorrhoid su�erers.

inxMedical.com

OProduct Key Requirements

• Office Based Treatment. Not restricted to hospital, clinic or surgery centers o No additional personnel or equipment required• Perform better than current rubber band ligation methods o Supplied pre-loaded with latex free bands > Allows for single or multiple banding during one procedure o Intuitive design for rapid adoption and pro�ciency o Dual action with integrated suction & band deployment triggers• Completely disposable

Design Support from Permian Plastics

Permian worked closely with inx Medical and their design engineer to modify the original design for moldability. Each part was reviewed for thickness of walls, aesthetics, functionality, and economy. By focusing on best injection molding practices the result was cost e�ective tooling for smooth manufacturing and assembly.

First Run for Clinical Evaluations

Permian produced a short run for clinical evaluations that Jim Vermeersch stated was completed on time and with excellent quality.

About Permian Plastics

Permian Plastics LLC is one of the premier plastic injection molding St. Louis, Missouri, companies. The company focuses on custom plastic injection molding and product design. Since 1994, Permian has delivered maximum value to their customers’ products by selecting the highest performance plastic material purchased at the lowest cost and through e�ciencies from design to delivery.

Permian Plastics’ In-House Team Developed Cost-Effective Tooling; Assembly, Pad Printing and GMP Clean Procedures.

PermianPlastics.com 636.978.4655 info@permianplastics.com