pet imaging of glutaminolysis in tumors by 18 f-(2s,4r)4-fluoroglutamine
DESCRIPTION
PET Imaging of Glutaminolysis in Tumors by 18 F-(2S,4R)4-Fluoroglutamine. Reporter: Fei Liu Supervisor: Prof. Zhi Yang 31 March 2014 Mentor: Nan Li and Hua Zhu. Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55. PET Imaging of Glutaminolysis in Tumors by 18F-(2S,4R)4-Fluoroglutamine. - PowerPoint PPT PresentationTRANSCRIPT
PET Imaging of Glutaminolysis in Tumors by18F-(2S,4R)4-Fluoroglutamine
Reporter: Fei Liu
Supervisor: Prof. Zhi Yang
31 March 2014
Mentor: Nan Li and Hua Zhu
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
Contents:
PET Imaging of Glutaminolysis in Tumors by18F-(2S,4R)4-Fluoroglutamine
Reporter: Fei Liu
Supervisor: Prof. Zhi Yang
31 March 2014
Mentor: Nan Li and Hua Zhu
Contents:PET Imaging of Glutaminolysis in Tumors by
18F-(2S,4R)4-Fluoroglutamine
Reporter: Fei Liu
Supervisor: Prof. Zhi Yang
31 March 2014
Mentor: Nan Li and Hua Zhu
Contents:
Conten
ts:
Conten
ts:
1 Background 2 Research3 Summary 4Development
Conten
ts:
1 Background 2 Research3 Summary 4Development
1Background
Conten
ts:
1 Background 2 Research3 Summary 4Development
2Research
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
2Research
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
2Research
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
2Research
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
2Research
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
2Research
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
2Research
Kung HF, et al, J Nucl Med, 2011, 52(12):1947-55.
Conten
ts:
1 Background 2 Research3 Summary 4Development
3Summary
The results support the feasibility of PET for the study of a fundamental change in tumor metabolism---high-rate glutaminolysis.
1 In vitro tumor cell uptake of 18F-(2S,4R)4-Fluoroglutamine is higer than uptake of 18F-FDG.
2In vivo PET studies showed significant tumor uptake adnd trapping inside tumor tissue in 2 different tuor models.
3
Conten
ts:
1 Background 2 Research3 Summary 4Development
4Development
Kung HF , et al, Chemistry. Science, 2013 , 342(6157):429-30.
4Development
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