pfizer contractor safety specification project ......the start of the work by the contractor's...

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1 Drawn up by: Roel Scheys Issue date: 13/03/17 Updated by: Julie De Bruyne Issue no: 05 PFIZER CONTRACTOR SAFETY SPECIFICATION PROJECT: CONTRACTING FIRM: Drawn up by: Name First name Position Date Contracting firm representative: Pfizer Project Manager or his/her appointee:

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Page 1: PFIZER CONTRACTOR SAFETY SPECIFICATION PROJECT ......the start of the work by the contractor's site supervisor and issued by the Pfizer project manager at the site where the work will

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Drawn up by: Roel Scheys Issue date: 13/03/17

Updated by: Julie De Bruyne

Issue no: 05

PFIZER CONTRACTOR SAFETY SPECIFICATION

PROJECT:

CONTRACTING FIRM:

Drawn up by: Name First name Position Date

Contracting firm representative:

Pfizer Project Manager or his/her appointee:

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TABLE OF CONTENTS

CHAPTER (hyperlink) TITLE

00 Basic EHS arrangements

01 Identification of the company and safety and health charter

02 List of subcontractors

03 Description of the work to be performed

04 Unique site notification

05 Training requirements

06 Legal inspections

07 Regulations concerning temporary site facilities contractors

08 Access to the Pfizer site

09 Access to the construction site

10 Construction site traffic – loading and unloading materials

11 General rules of conduct and supervision

12 Weekend work

13 General work permit

14 Hot work (welding, grinding, burning)

15 Entering enclosed spaces

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16 Working on fire extinguishing systems

17 Working above aseptic production zones

18 Electrical Work Permit

19 Lock-out - Tag-out

20 Personal protective equipment

21 Collective protective equipment

22 Signalisation

23 Working at height

24 Automated equipment for working at heights (aerial hoisting equipment, scissor lifts…)

25 Use of scaffolding, mobile stairway towers

26 Use of ladders

27 Working on roofs

28 Use of personal fall protection

29 Working on electricity

30 Use of hoisting and lifting equipment

31 Excavation work

32 Storage and use of dangerous substances

33 Use of knives

34 Demolition works

35 Fine dust during construction & demolition works

36 Storage and removal of soil, waste, rubble and debris

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37 Removal and transport of hazardous materials

38 Order and neatness

39 Assistance & Measures in the case of work accident

40 Fire

41 Evacuation

42 Safety & health organisation at the work site

43 Construction site organization

44 Project specific risks

45 Action list to be executed before start of works

ALWAYS APPLICABLE Chapter 0 BASIC EHS ARRANGEMENTS

0.1 Personnel safety: The personnel employed by the contractor (site supervisor, foreman, workers) must be informed and have sufficient knowledge of the applicable procedures, tender specifications and technical specifications.

0.2 Authorisation to enter the work sites (= gate list): All contractor companies doing activities which are not mentioned on the exception list must present a valid safety certificate for contractors (SCC), comparable with VCA certificate before they will be added to the gate list. Exception list (no certificate needed):

Description activity Telecommunication Software (maintenance, inspection)

Hardware (communication technics, maintenance, inspection) Gates and doors (maintenance, assemby) Dry construction working office buildings Prefabricated building and tents Engineering Mechanical (incl. piping) Engineering civil

Engineering E&I/Automation Engineering multidisciplinair Commercial cleaning

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Gardening Street cleaning

Winter maintenance service Pest control Cleaning other Waste treatment Waste transportation Storage extern (logistics) Filling extern (logistics) Packaging service (logistics)

Logistics service (other) Recruitment & selection Personnel management / HRM

Repair tools in production installations & workshop activities Laboratory and inspection service (other) Catering Services

Security supervision Communication Services & PR Training, education & coaching Strategic Consultancy Marketing Consultancy Technology Consultancy Controlling, finances and accounting Management Consultancy HR Consultancy (incl. assessment centers) IT Consultancy Canteen, kitchen equipment (maintenace, inspection) Laboratory furniture & equipment (assembly, maintenace, inspection) Repair / maintenance equipments (according to manufacturer's warranty)

0.3 Rules for subcontracting: A maximum of 2 levels of subcontracting are permitted. No temporary/interim workers are allowed.

0.4 Minimum age: Only persons 18 years or older are eligible to work at the work sites.

0.5 Contractor safety officer: Each contractor is obliged to designate a safety officer, regardless of the amount of work to be done. The safety officer must be clearly identifiable (purple sticker on helmet). In the case of extensive work with a high risk and/or works with more than 25 persons irrespective of whether they are located in one site or across multiple sites, this will be a half-time position; when there are more than 50 employees, it will be a full time position.

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The safety officer will participate daily in the safety briefings of the various sites during the period that his company employs personnel at the site. The safety officer is responsible for promoting the safety of the personnel of his company and the subcontracting companies working for his company. This person does need to train his employees in the applicable safety measures within Pfizer (blue sticker – see chapter 9).

0.6 Language: The foremen must speak the languages of the workers under their supervision. The safety officer and the foreman must serve as a contact between their own personnel and the Pfizer contact, and must always be on site during the work. The safety officer and the foreman shall always speak at least Dutch or English.

0.7 Work permit (cf. chapter 13): No work may be performed without a work permit. Violation of this rule shall result in immediate dismissal. The work permit is prepared before the start of the work by the contractor's site supervisor and issued by the Pfizer project manager at the site where the work will be carried out.

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ALWAYS APPLICABLE Chapter 1 IDENTIFICATION OF THE COMPANY AND SAFETY AND HEALTH CHARTER

Commissioning authority: PFIZER, Rijksweg 20, PUURS

SAFETY and HEALTH CHARTER

Construction project:

Construction site:

Company (sub)contractor: .............................................................................................................................................

Address: .............................................................................................................. No. ....................................

Postal code: ......... City: .................................................................................................................................

Tel.: ........................................... Mobile: ............................................... Fax: ................................................

Information specific to construction site:

your Site Supervisor: ........................................................................................... tel/Mobile: ........................

your safety & health manager at the work site: ................................................. tel/Mobile: ........................

your First Aid assistant(s): ................................................................................... tel/Mobile: ........................

subcontractors: YES / NO ; if yes, see relevant contact information in Chapter 2 ..........................................

1. Undersigned will return this completed and signed safety & health charter, and confirms that he has reviewed and clearly understood the safety prescriptions applicable to the construction site. He agrees to strictly comply with the safety and health requirements as well as the stipulations of the applicable laws (in particular the Royal Decree of 25/01/2001 on temporary or mobile construction sites)

2. Undersigned declares to have received the safety and health plan for this construction site and to take the needed initiatives to inform all of his employees, and if necessary also the

(sub)contractors working for him, concerning the contents of this safety & health plan.

....... / ....... / ..... .............................................................................. .................................

date Name and position signature

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Applicable / N/a Chapter 2 LIST OF SUBCONTRACTORS

No Company name Contact Description of the work to be performed by the subcontractor

1

Name:

Tel.:

e-mail:

2

Name:

Tel.:

e-mail:

3

Name:

Tel.:

e-mail:

4

Name:

Tel.:

e-mail:

5

Name:

Tel.:

e-mail:

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ALWAYS APPLICABLE Chapter 3 DESCRIPTION OF THE WORK TO BE PERFORMED

In the following table, please provide an overview via a step-by-step plan of the work to be performed and the tools / products that will be used.

Step Activity to be performed Tool(s) / products to be used

1

2

3

4

5

6

7

8

9

10

11

12

13

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Applicable / N/a Chapter 4 (UNIQUE) SITE NOTIFICATION(S)

4.1 Contractors in the construction sector are bound by a number of legal requirements concerning the reporting of work. DEPENDING ON THE TYPE AND VOLUME OF THE WORK TO BE PERFORMED, DIVERSE NOTIFICATIONS must be made to a number of institutions that partially contain the same data. More details on these various notifications (when required, who must prepare them …) can be found in the table below.

Applicable? TYPE OF NOTIFICATION

Applicable

N/A

Notification of the work 30bis to National Social Security Office;

For which work is notification required? Notification is obligatory for all work on immovable property (new area of application regarding notification of work from 01/06/2009).

• Every contract “client – contractor who does the declaration” starting from 5000 euro (taxes excluded) with at least 1 subcontractor or

• Every contract “client – contractor who does the declaration” starting from 30.000 euro (taxes excluded) with or without a subcontractor

Who must make the notification? The notification must be done by the contractor hired by the commissioning authority.

When must the notification take place? Notification must take place before the work starts.

Applicable

N/A

The notification of work to the National Action Committee for Safety and Hygiene in the Construction Sector (NAVB);

For which work is notification required? Notification is obligatory for work whose completion time amounts to 30 working days or more. Notification is also obligatory for special work, work with a health risk and/or work that creates a nuisance, even if the completion time is less than 30 working days, unless it concerns minor maintenance or repair work.

Who must make the notification? The notification must be done by the contractor (natural or legal person, contracting authority or contracting partner of the contracting authority) who is executing the work in question.

When must the notification take place? Notification by the contractor to the NAVB must be done no later than 15 days before the contractor begins work.

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In the case of force majeure, due to unforeseen circumstances or if the 15-day period is not feasible, this must be communicated to the NAVB by telephone on the same day, and confirmed within 48 hours by a notification.

Applicable

N/A

The notification of temporary or mobile construction sites to the FPS Employment, Labour and Social Dialogue - Work Safety Administration (AAV);

For which work is the notification required? The notification of temporary or mobile construction sites is obligatory for all work:

• that last longer than 30 working days and in which more than 20 employees are on the job at the same time (see article 26 § 2) • whose expected work volume is greater than 500 man-days.

Specific 'hazardous' works (see article 26 § 1) that take longer than 5 working days must also be reported.

Who must make the notification? The notification must be done by the construction management charged with supervision. If multiple management entities are active, it is the responsibility of the construction management that is first to perform work at the construction site.

When must the notification take place? The notification must take place at least 15 calendar days before starting the work. In the case of urgent works or short-term planning, the notification must take place no later than the day on which the work begins.

Applicable

N/A

The notification of asbestos removal work to the FPS Employment, Labour and Social Dialogue / Medical Inspection - Work Hygiene and Industrial Medicine Administration (AHG);

For which work is the notification required? Notification is obligatory before the start of:

• all asbestos removal work or the removal of material containing asbestos. • work to replace, maintain or make limited repairs to tubes and piping whose insulation contains asbestos and that is done using

asbebags.

Who must make the notification? The notification must be completed by the contractor performing the asbestos removal work. When must the notification take place? The notification of asbestos removal work must take place no later than fourteen days before the start of work and whenever significant changes

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to the original report take place with respect to the procedures being used.

Applicable

N/A

The notification of work in a hyperbaric environment to the FPS Employment, Labour and Social Dialogue / Medical Inspection - Work Hygiene and Industrial Medicine Administration (AHG);

For which work is the notification required? Notification is obligatory before the start of: each work assignment executed in a hyperbaric environment in which workers are subject to a pressure greater than 100 hectopascal above local atmospheric pressure.

Who must make the notification? The notification must be done by the contractor performing the work in question.

When must the notification take place? Notification of work in a hyperbaric environment must take place no later than fourteen calendar days before the scheduled start of the work.

Applicable

N/A

The notification of sandblasting work to the FPS Employment, Labour and Social Dialogue / Medical Inspection - Work Hygiene and Industrial Medicine Administration (AHG).

For which work is the notification required? Notification is obligatory before the start of all abrasion work via sandblasting and de-sanding in which the sand or other granules used contain more than 1 percent free silicon dioxide.

Who must make the notification? The notification must be done by the contractor performing the sandblasting work.

When must the notification take place? The notification of the sandblasting work must take place no later than 10 days before the start of work.

Vt

Nvt

In the case of earthworks, a cable and piping plan must be requested via the KLIP portal. For which works must plans be requested from the KLIP? Plans must be requested from the KLIP by the contractor who will execute earthworks on the territory of the Flemish Region. The obligation to request a cable and piping plan does not apply in cases of force majeure and for earthworks carried out manually. The requirement also does not apply if it concerns earthworks on land owned or managed by the person who will carry out the earthworks and if that person knows that nothing has changed concerning the presence and location of the cables and piping since the last request. Who must submit the application? The request must be made by the contractor performing the earthworks.

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When must the request be made? The notification of the earthworks must take place no later than 15 days before the start of work.

4.2 Using the application 'UNIQUE SITE NOTIFICATION/UNIEKE WERFMELDING' at the social security portal site, contractors performing WORK ON IMMOVABLE PROPERTY (new area of application 30bis from 01/06/2009), must notify this work ELECTRONICALLY.

ALWAYS APPLICABLE Chapter 5 TRAINING REQUIREMENTS

5.1 For the SPECIFIC SAFETY TASKS contained in the following table, the contractor will provide a copy of the qualifications of its authorised personnel BEFORE START OF WORKS:

No

Description of the training

Applicable or Not?

Certificate by a recognized

examination centre (VCA)

Health certificate - Safety function

Competency certificate for

immediate employer (*)

Pfizer in-house training

Due Date

Signature as confirmation.

5.2 Safety video Access to the Pfizer site

X Applicable X

5.3

Site-specific safety training for contractor

supervispr

X Applicable X

5.4a Crane operator mobile crane

Applic

N/A

X

X

5.4b Crane operator tower crane

Applic

N/A X X

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5.5a Rigger/ Training on

lifting/hoisting equipment and the securing of critical loads

Applic

N/A X

X

(Position requiring increased alertness)

5.5b Training on hoisting non- critical loads

Applic

N/A X

5.6 Forklift operator

Applic

N/A X X

5.7 Scissor lift operator

Applic

N/A

X

X

5.8

Aerial work platform operator

Applic

N/A

X

X

5.9 Excavator Operator

Applic

N/A X X

5.10

Scaffolding inspector

Fixed scaffolding

Applic

N/A

X

5.11

Scaffolding inspector

Modular scaffolding

Applic

N/A

X

5.12

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Scaffolding builder

Fixed scaffolding

Applic

N/A X

5.13

Scaffolding builder

Modular scaffolding

Applic

N/A

X

5.14 Scaffolding user

Applic

N/A X

5.15 Mobile stairway tower builder and inspector

Applic

N/A X

5.16 Tank watch

Applic

N/A X

5.17 Fire watch

Applic

N/A X

5.18 Safety watch confined space

Applic

N/A X X

5.18 First Aid assistant

Applic

N/A X

5.19 Asbestos remover

N/A X

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Applic

5.20 BA4 - BA5

Applic

N/A X

5.21 Safe working at heights

Applic

N/A X

5.22 Prior radiation training is required when working on the E-beam (DSF3)

Applic

N/A

X

5.23 Working with personal Fall Protection

Applic

N/A X

(*) if it concerns a competence certificate awarded by the own company the content of the course should be presentable and, if asked, handed to Pfizer.

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ALWAYS APPLICABLE Chapter 6 INSPECTIONS / CHECKS OF WORK EQUIPMENT - TOOLS

6.0 The inspections / checks of work equipment must be performed according to the frequencies and specifications established in the following table. The user of the work equipment / tools always must verify its proper operation before use. If serious defects / damage is observed, the work equipment / tools must be immediately taken out of service for repair.

No Type of work equipment:

Will this work equipment be used?

Inspection / checked by:

Frequency of the inspection / check

How must the inspection / check be demonstrated

Certified Technical Inspection Service

(CTIS)

Authorised person (of the

contracting firm itself)

6.1 Tower crane

YES

NO X After construction and every 3

months thereafter

Most recent inspection report must be present on site

6.2

Mobile crane

YES

NO X Every 3 months

6.3

Forklift

YES

NO X Every 3 months

6.4 Scissor lift

YES

NO X Every 3 months

6.5 Aerial work platform

YES

NO X Every 3 months

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6.6 Material lifts

YES

NO X

Every 3 months Most recent inspection report must be present on site

6.7 Personnel lifts

YES

NO

X

Every 3 months

6.8

Lifting and hoisting

equipment chains, hooks, hoisting

belts, yokes, etc.

YES

NO X Every 3 months CTIS inspection sticker

6.9

Personal

protective equipment safety harnesses and

belts, lanyards, rescue ropes, fall arrest equipment, accessories,

etc.

YES

NO

X Yearly and after each fall CTIS inspection sticker

6.10

Temporary power (electrical) box/cart

YES

NO X After connection, and yearly thereafter

CTIS inspection sticker

6.11

Modular scaffolding (e.g. Alu mobile scaffolding)

YES

NO

X Every week

Scaffolding inspection card / assembly and disassembly

instructions (should be available and fixed on

scaffolding)

6.12

Fixed Scaffolding and

X Every week

Scaffolding inspection card

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mobile scaffolding YES NO fixed to scaffolding / assembly and disassembly instructions and calculation notes (should

be handed to Pfizer if requested)

6.13 Mobile stairway tower

YES

NO X Monthly

6.14

Ladder

YES

NO X Yearly

The inspection result must be present on the equipment

(inspection sticker or colour code as described in a

procedure)

6.15

Step ladder

YES

NO X Yearly

6.16

Fire extinguishers

YES

NO X Yearly

6.17

Electrical hand tools

YES

NO X Yearly

6.18 Electrical cables

YES

NO X Yearly

6.18 All GRINDERS must be equipped with a DEAD MAN'S SWITCH. A dead man's switch requires a double action to start the unit, and the machine stops immediately after the start button is released. The grinder must also be equipped with a HANDLE and PROTECTIVE SHIELD. SELECTION OF THE GRINDING DISC must be done in function of the maximum RPM of the grinder. The maximum RPM of the grinding disc must ≥ maximum RPM of the grinder.

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6.19 MAGNETIC DRILLS must always be secured to the structure on which they are mounted using a SAFETY CHAIN OR SAFETY

STRAP . Improper attachment (e.g. due to paint on metals) or the sudden loss of the magnetic force (e.g. as a result of a power failure) could cause the drill to be ejected, with possible injury to people.

6.20 Use of a grinding disc to cut bricks is not allowed. Only the use of a COBBLESTONE CUTTER, STONE CUTTER OR WATER COOLED DIAMOND SAW is allowed.

Applicable / N/a Chapter 7 REGULATIONS CONCERNING TEMPORARY SITE FACILITIES CONTRACTORS

7.1 If a site or material container is needed during performance of the works on site, the installation may take place only after consultation with the Pfizer contact responsible for contractor safety and construction. A specific area will be assigned to the contractor for installation of the container. Before any construction may be erected, formal approval must be given by the responsible Pfizer contact. This approval will be given for a period of the duration of the project, with a maximum of 2 years. After this period, the approval needs to be revised based on ongoing activities.

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7.2 The contractor may only store material in the area assigned to the contractor. Any materials stored outside this area will be removed. Costs resulting from this removal will be charged to the contractor.

7.3 Each STAIRWAY with more than 2 stairs must be equipped with a railing. Two railings are required if there are more than 8 stairs or the stairway is wider than 1.5 meters. The step must be made according to the applicable regulations. The use of OPEN PALLETS as step or walkway to the container is PROHIBITED. All exterior doors must open outward.

7.4 The MINIMUM WIDTH for all passages, door openings,… is 70 cm. This applies to both normal and emergency exits. The contractor must take into account doors that open outward, which could block passages.

7.5 Hanging flags or advertising panels is not allowed. Each container must contain a TAG with the NAME of the firm, and the NAME and TELEPHONE NUMBER OF THE CONTACT PERSON. The identification used should be a Pfizer sticker witch will be given to the contractor after approval

7.6 Storing materials on top or between containers is NOT ALLOWED.

7.7 The contractor is responsible for the REGULAR CLEANING of its containers (material, office containers or other).

The HOUSEHOLD WASTE produced by the contractor must be deposited in the appropriate waste containers. These Pfizer containers are emptied periodically by Pfizer. If a contractor brings its own waste container for household waste, it must be equipped with a WASTE BAG and must REMAIN CLOSED AT ALL TIMES in order not to attract vermin. In this case, the contractor itself is responsible for periodically emptying its own waste container (removing the waste bag).

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7.8 A common dining room is foreseen (contractor cafeteria). This is cleaned on a regular basis by Pfizer. No authorisation will be given for the placement of individual containers to serve as dining rooms.

7.9 Toilet facilities will be made available to the contractor in the contractor cafeteria. These will be cleaned by Pfizer on a regular basis (daily). Deviations to this must be formally approved by the Pfizer contact responsible for contractor safety and construction.

7.10 It is NOT ALLOWED to perform work in the contractor village that is unrelated to the work to be carried out on behalf of Pfizer. It is also NOT ALLOWED to use the allocated area to stock material that is unrelated to the work to be carried out at the site or to stock material in other than the assigned location.

7.11 The allocated area must be managed with due care by the contractor. Therefore, it must regularly CLEAN UP the zone and, if necessary, carry out the necessary repair work. The contractor must ensure that water and condensate cannot accumulate.

7.12 Vehicles are only allowed for loading and unloading materials. Vehicles must be parked at the designated location, i.e. the contractor parking area.

The storage location, and loading and unloading zones for materials and equipment must be determined such that loading, unloading and other activities do not pose risks to other personnel (own and third parties) present in the area assigned to the contractor. If obstructions need to be selectively placed in order to achieve this, the contractor is responsible for this.

7.13 If the contractor wishes to store FUELS at its assigned location, this storage area must meet all requirements of Vlarem II. This includes in particular, drip trays, double-walled tanks, overpressure protection, leak-proof underground, etc. The requirements for open storage areas are as follows:

• Closed storage areas or storage in basements is prohibited • Never place under office containers • Full and empty cylinders must be stored separately from each other with a clear indication “full” and “empty” • Protection against sun and other heat radiation is used (shelter). • Ventilation is foreseen above and below • The pictogram “Fire, open flame and smoking prohibited” is applied if flammable gases are being stored

The following minimum safety distances must be respected between the inflammable gases (e.g. acetylene, propane,…) and the oxidising gases (oxygen):

• Storage capacity up to a maximum of 1,000 litres (water content): 2 m • Storage capacity up to a maximum of 5,000 litres (water content): 5 m

These safety distances also apply to empty, not gas-free receptacles.

7:14 Pfizer makes ELECTRICITY available for lighting, small appliances and small hand tools (drill, grinder, …). If heating is necessary in the container, the contractor must provide its own electric heater. The contractor is expected to use this heating with due care. It is not allowed to heat the container with doors and windows open. If no one will be present in the containers for a prolonged period, the heating must be turned off.

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7.15 The permanent storage and processing of waste is not permitted. It is prohibited to bring external waste to the Pfizer site.

7.16 The surface area of a zone determines the minimum NUMBER OF FIRE EXTINGUISHERS that must be present. Based on a normal fire risk, the following must be installed:

• Per 150m², at least 1 fire extinguisher with a capacity of 6 kg powder or 6 l foam, 1 extinguisher (1 powder or foam extinguisher 6 kg = 2 CO2 of 5 kg) • Per 225 m², at least 1 fire extinguisher with a capacity of 9 kg powder or 9 l foam; 1.5 extinguishers (1 powder or foam extinguisher 9 kg = 3CO2 of 5 kg) • At least 2 fire extinguishers per zone • If a zone is smaller than 100 m², 1 fire extinguisher of at least 6 kg powder or 6 l foam is sufficient • The fire extinguishers must always be easily accessible and located within 20 meters walking distance.

7.17 At the end of work at the site, the contractor, at its own expense, must return to its original state the premises or container made available to it. This must take place WITHIN 2 WEEKS after finishing work at the site. This means that all structures, cables and pipes installed by the contractor must be removed and the area cleaned up completely.

Any damaged parts that are the property of Pfizer must be repaired by the contractor.

7.18Compliance with this requirement within the contractor village will be frequently monitored via ROUNDS. If deviations are found with respect to the requirements, the contractor must take all necessary measures to comply with the regulations. If the contractor fails to do what is required, Pfizer will take the necessary measures at the expense of the contractor.

7.19 Permanently installed machines (table saw, drill press, …) must always be equipped with an instruction card in the language of the user. This instruction card must hang in the immediate vicinity of the machine.

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ALWAYS APPLICABLE Chapter 8 ACCESS TO THE PFIZER SITE

8.1 Access to the site only after obtaining an ACCESS BADGE

8.2 An access badge must be requested BY MAIL AT LEAST 2 DAYS BEFOREHAND

8.3 An access badge is granted only after:

* the prior badge request by the Pfizer commissioning authority * submission of the appropriate identification (passport, limosa forms for foreighn workers)

* after following the general EHS training film and successful completion of the corresponding test

Registration is done via ONYX (http://www.pfizerpuurscontractors.com)

8.4 The access badge must ALWAYS BE VISIBLE.

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ALWAYS APPLICABLE Chapter 9 ACCESS TO THE CONSTRUCTION SITE

9.1 SITE ENTRANCES / GATES are kept closed to prevent unexpected visitors to the construction site.

9.2 AT THE END OF THE WORKING DAY, the access routes to the work site must be LOCKED.

9.3 A CONSTRUCTION SITE SIGN will be installed at all major access routes to the work site. This sign indicates the minimum STANDARD PERSONAL PROTECTIVE EQUIPMENT to be worn and the TELEPHONE NUMBERS of the Pfizer PROJECT MANAGERS.

9.4 All supervisors of the contractor are required to follow “Pfizer EHS training” each year. This training will be given on Thursdays of all odd weeks from 1:00 to 3:00 pm in the training room adjacent to the contractor cafeteria. Attendance of this training is documented and participants receive a PURPLE sticker for their helmet to verify participation. The trained supervisor will receive the training-related toolboxes (digital or hard copy).

The trained supervisor in turn is responsible for training all of its employees (incl. subcontractors) on the basis of the toolboxes before the start of their activities. He will submit the list of participants to the Safety Supervisor of the engineering department and will receive a number of BLUE stickers corresponding to the number of participants. These must be worn visibly on the helmet.

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ALWAYS APPLICABLE Chapter 10 CONSTRUCTION SITE TRAFFIC – LOADING AND UNLOADING MATERIALS

10.1 PARKING in the contractor parking area or the Lease 4 parking area.

10.2 Belgian TRAFFIC RULES apply, including the wearing of a seat belt.

10.3 MAXIMUM ALLOWABLE SPEED is 20 km/hour. Passing moving vehicles is prohibited. Pedestrians and bicyclists always have right of way. In case of excavators, the maximum allowed speed is 10 km/h.

10.4 FIRE DEPARTMENT ACCESS ROADS and important passageways may not be blocked.

10.5 ALL TRANSPORT to the construction site takes place via the foreseen roads and passageways. If vehicles must be driven in other zones, arrangements for must be made with the relevant supervisor(s).

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10.6 LOADING AND UNLOADING at the work site may only take place subject to prior consultation with the site supervisors.

10.7 Vehicle MANOEUVRES will always take place under supervision.

10.8 Occupying parts of the public road for construction site purposes must be kept to a minimum and may only take place after prior consultation with the competent authorities.

10.9 All movements or removal of this signalling required to perform the work must be notified to the contractor responsible for the signalling. A copy of the TRAFFIC SIGNAL LING PLAN approved by the competent authorities will be made available at the work site and submitted for inspection to the safety coordinator.

10.10 EMERGENCY DOORS MAY ONLY BE OPENED IN THE CASE OF EMERGENCY. They may NOT be used as standard ACCESS TO THE SITE. To make an emergency door a standard access, the project must equip it with an “airlock” secured with a badge. The unauthorised opening of emergency doors will be sanctioned.

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ALWAYS APPLICABLE Chapter 11 GENERAL RULES OF CONDUCT & SUPERVISION

11.1 Pfizer or its appointees have the right to INSPECT the work at all times.

11.2 In the case of SERIOUS / REPEAT VIOLATIONS, Pfizer is entitled to HAVE THE WORK STOPPED.

11.3 In the case of SERIOUS / IMMEDIATELY DANGER FOR PERSONS OR THE ENVIRONMENT Pfizer has the right to immediately take suitable actions AT THE EXPENSE OF THE CONTRACTOR(S) that remain in default.

11.4 Persons who do NOT COMPLY with the safety and health guidelines and/or who are unable to identify themselves, will be ORDERED OFF THE CONSTRUCTION SITE.

11.5 An absolute BAN ON ALCOHOLIC DRINKS AND DRUGS applies to the Pfizer site.

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11.6 The POSSESSION OR USE OF ALCOHOLIC DRINKS / DRUGS on the Pfizer site is considered a serious violation of the safety regulations and will result in IMMEDIATE REMOVAL OF THE PERSON IN QUESTION.

11.7 Smoking is only allowed in OPEN AIR, OPEN BUILDING SHELLS and the FORESEEN SMOKING AREAS.

11.8 NO EATING AT THE WORK SITE. Eating may only take place in the areas foreseen for such.

11.9 TOILETS in contractor village or office buildings.

11.10 It is STRICTLY PROHIBITED to make use of WORK EQUIPMENT (scissor lifts, pallet transporter,…) and TOOLS that belong to Pfizer at ONE's OWN INITIATIVE AND WITHOUT THE FORMAL AUTHORISATION OF PFIZER.

11.11 Every contractor company needs to have an attendance list with contractors who are working on Pfizer on a daily basis and should be able to present it to Pfizer if requested.

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ALWAYS APPLICABLE Chapter 12 WORKING HOURS & WEEKEND WORK

12.1 The DURATION of the activities as specified in the GENERAL WORK PERMIT must ALWAYS BE RESPECTED. WORKING LONGER is possible ONLY AFTER FORMAL APPROVAL BY PFIZER.

12.2 The following activities may be performed only in the weekend (Saturday 6:00 a.m. – Sunday 6:00 p.m.):

* transport and removal of machines, material and equipment through the building

* dangerous hoisting and lifting work above buildings

12.3. If activities are planned for a weekend, approval is needed in advance (Pfizer contact person) as the involved departments need to be informed.

ALWAYS APPLICABLE Chapter 13 GENERAL WORK PERMIT

13.1 For all operational activities, a GENERAL PFIZER WORK AUTHORISATION/PERMIT must be requested and received prior to execution of the work.

13.2 Depending on the specific risks and working conditions, the following SUPPLEMENTARY WORK PERMITS may be required:

o FIRE PERMIT (see chapter 14) o PERMIT FOR ENTERING ENCLOSED SPACES (see chapter 15) o SHUT DOWN OF FIRE EXTINGUISHING SYSTEMS (see chapter 16) o CEILING PERMIT (see chapter 17) o ELECTRICAL WORK PERMIT (see chapter 18)

The use of one or more of these supplementary work permits, however, does not prejudice the further use of the corresponding General work permit.

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13.3 The General work permit is VALID FOR A MAXIMUM OF 7 SUCCESSIVE WORKING DAYS. The Pfizer commissioning authority, however, is always free to limit the duration of the permit.

13.4 The work permit is prepared before the start of work by the PFIZER PROJECT MANAGER and then reviewed together with the contractor's SITE SUPERVISOR and possibly supplemented with additional task-specific safety measures before being issued by the PFIZER PROJECT ENGINEER at the construction site.

13.5 When requesting the work permit, account must be taken of the fact that SUFFICIENT TIME must be allowed to thoroughly and safely handle the needed PREPARATORY WORK (securing the installation, installation of scaffolding…).

13.6 If the work permit is APPROVED, it is SIGNED BY ALL CONCERNED PARTIES and the planned work may be executed according to the arrangements contained in the work permit.

13.7 The representative of the contractor who signs the permit upon issue is responsible for COMMUNICATING to each of his COLLEAGUES the EHS requirements as these are established in the permit. Each employee of the contractor who contributes to the work described in the work permit must sign off on the back of the work permit for approval, indicating that he/she received and understands the instructions described on the permit. Contractor employees who have not signed off on the back of the work permit and therefore are not aware of the safety requirements may never perform the work described in the work permit.

13.8 The General work permit is always drawn up in DUPLICATE. The ORIGINAL WHITE COPY of the permit must be PRESENT AT THE WORK PLACE. The YELLOW COPY of the permit remains in the possession of the PFIZER PROJECT RESPONSIBLE. ATTENTION: no changes may be made to the original without changing the carbon copy.

13.9 If during execution of the work it appears that the SECURITY ARRANGEMENTS as established in the permit CANNOT BE COMPLIED WITH, the work must be STOPPED TEMPORARILY and the Pfizer managers (site supervisor/project manager) must be notified immediately. Consultation must take place to determine whether and how the work can be continued.

13.10 Pfizer may request the work permit at any time during execution of the work for INSPECTION purposes. If SERIOUS VIOLATIONS are detected, this can result in the IMMEDIATE REVOCATION OF THE WORK PERMIT and consequently STOPPAGE OF THE WORK.

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13.11 The commissioning authority and the contractor for the work will agree among themselves whether or not the work permit must be TURNED IN daily. If NO ACTIVITIES take place on a specific day within the validity period of the permit, the license must be TURNED IN to the commissioning authority. Upon restart of the work, the permit is retrieved from the Pfizer project repsonsible and information obtained concerning whether the conditions at the workplace are unchanged since the last working day.

13.12 The contractor's SITE SUPERVISOR will check daily whether the conditions on the work floor are consistent with the arrangements made in the permit. As confirmation, he must enter his initials, the date and the number of employees.

13.13. At the end of the work, the contractors' SITE SUPERVISOR will sign for confirmation that the job was properly completed and the workplace cleaned. The PFIZER PROJECT ENGINEER verifies that all the requirements were met, and signs for acceptance.

13.14. A permit is always completed IN THE NAME OF THE MAIN CONTRACTOR. ONLY THE MAIN CONTRACTOR receives the permit from the commissioning authority.

Applicable / N/a Chapter 14 HOT WORK / FIRE PERMIT

14.1 A FIRE PERMIT must be obtained for ALL FLAMMABLE WORK (the only exceptions are the welding container/corners in the contractor village and the maintenance shops)

14.2 A fire permit must also be obtained for the use of NON EX-PROOF ELECTRIC TOOLS IN EX ZONES.

14.3 The FIRE PERMIT must always be PRESENT AT THE WORKPLACE.

14.4 The fire permit must be RE-REQUESTED AND ISSUED DAILY . Before start of the works 1 copy needs to be delivered to the Pfizer security (FCR). After finishing of the works, the extra copy (double) needs to be delivered as well to the Pfizer security (FCR).

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14.5 During execution of the hot work, at least 1 ABC FIRE EXTINGUISHER of minimum 6 kg must ALWAYS be in the vicinity.

14.6 In the case of SPARKING, surrounding zones must be protected with FIRE-RESISTANT BLANKETS.

14.7 A PERMANENT GUARD / FIRE WATCH is required for HOT ROOFING WORK or when this is specified on the fire permit.

14.8 At the END OF THE DAY'S WORK or during breaks (no one at workplace), GAS BOTTLES MUST BE CLOSED and THE PRESSURE IN HOSES AND PRESSURE GAUGES RELEASED.

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14.9 Gas bottles must be handled with extreme caution. Gas bottles not being used (including empty bottles) must be STORED OUTSIDE THE BUILDING at a fixed location IN AN UPRIGHT POSITION, SECURED, equipped with the PROTECTIVE CAP and PROTECTED FROM THE SUN.

14.10 Although there are no open flames or high temperatures with electrowelding, there is a risk of fire. Because of this risk, the following measures are applicable:

* prohibited on pipes with a cylinder bore > 125 mm

* allowed on pipes with a cylinder bore < 125 mm ONLY with full-time supervision until 1 hour after the works end.

Exceptions to this rule need to be agreed with the Pfizer Engineering Department and are only allowed when extra safety measures are taken (e.g. infrared measurement)

14.11. While performing hot work, the contractor must always wear FIRE RETARDANT CLOTHING according to the standard EN ISO 14116 - Protection against heat and flame, and the clothing of welders must meet the EN ISO 11611 standard for protective clothing for use in welding.

14.12. While performing GRINDING ACTIVITIES, goggles or safety glasses IN COMBINATION WITH A FACE SHIELD must be used.

14.13. Zones with an explosion hazard must be equipped with the necessary signalisation. Thus the explosion hazard zone in a work zone around the charging points for forklifts must be clearly identified (zone to be demarcated with tape/cable and foreseen with pictogram).

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Applicable / N/a Chapter 15 ENTERING ENCLOSED/CONFINED SPACES

15.1 An enclosed space is a space that is DIFFICULT TO ACCESS (narrow entrance / exit) and a space in which a HAZARDOUS ATMOSPHERE can be present. A hazardous atmosphere can be formed by oxygen displacing gases (nitrogen, argon …), poisonous and or explosive fumes.

15.2 EXAMPLES of the most common enclosed spaces are: manholes, storage tanks, steam boilers…

15.3 Note: TEMPORARILY CREATED SPACES where a hazardous atmosphere might be present must be considered and treated according to the instructions for enclosed spaces. Examples of these include: welding tents, covered trenches close to gas lines, tents close to N2 systems…

15.4 Before entering an enclose space, a SEPARATE WORK PERMIT must be obtained. The permit for entering an enclosed space must be RE-ISSUED DAILY.

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15.5 Safely entering an enclosed space requires much preparation (measurements, rescue equipment…). For this reason, always submit your request AT LEAST 1 DAY BEFOREHAND.

15.6 Entry of an enclosed space may only be initiated after performing the needed DAILY PRELIMINARY CONTROL MEASUREMENTS (oxygen, LEL…). These measurements need to be executed by a trained gas analyst.

15.7 While the enclosed space is being accessed, there must ALWAYS BE AT LEAST 1 TRAINED SAFETY GUARD CONTINUOUSLY SUPERVISING the safe execution of the work.

15.8 The person in the enclosed space must ALWAYS wear a PERSONAL OXYGEN METER.

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Applicable / N/a Chapter 16 WORKING ON FIRE EXTINGUISHING SYSTEMS

16.1 Work on or shutting down CRITICAL FIRE SYSTEMS (SPRINKLERS, SMOKE ALARMS, MODIFICATIONS TO FIRE WALLS, FIRE DOORS,…) or USING FIRE EXTINGUISHING WATER must ALWAYS be REQUESTED from Pfizer AT LEAST 24 HOURS beforehand. The work may only be performed if a valid RSVP tag is obtained via the Pfizer Safety Department.

16.2 TAPING OVER SMOKE DETECTORS is only allowed in exceptional circumstances, after approval by the Pfizer responsible and EHS department. If smoke detectors must temporarily be taken out of service, this must be requested and an RSVP tag need to be obtained.

Applicable / N/a Chapter 17 WORKING ABOVE ASEPTIC PRODUCTION ZONES

17.a.1 If access is needed to a ceiling above an aseptic production zone, a CEILING PERMIT must be requested and approved beforehand. Failure to follow this procedure can result in VERY SERIOUS QUALITY PROBLEMS.

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17.a.2 The simultaneous execution of work (whether or not by different parties) on work floors located on top of each other can entail the danger of falling objects.

If there is direct visual contact between two work floors located on top of each other that is accompanied by activities entailing the risk of falling objects, access to the danger zone in the lower work floor must be prevented as long as work is being conducted on the upper level.

If there is no direct visual contact between the two work floors located on top of each other, but falling/loose objects could still (albeit indirectly through openings) reach the lower working level, at least the openings between the work floors must be blocked using tarps.

Applicable / N/a Chapter 18 ELECTRICAL WORK PERMIT

18.1 ALL OF THE WORK LISTED BELOW requires the prior application for and approval of an electrical work permit.

• work on a live electrical installation (>50V AC and 75V DC)(1)

o Work in the vicinity of a live electrical installation Measurement in a BA5 labelled panel

• Working on high-voltage systems

• Mechanical work (grinding, drilling, cutting,…) in the vicinity (<1 meter) of live power cables and not locally fused cables.

(1) Working under/in the vicinity of power is allowed as long as the IP2X conditions are met. For the replacement of lamps under power, this means that the fixture is intact and is not removed.

18.2 The obligation to use an electrical work permit applies to all (including Pfizer employees). The electrical work permit is valid for MAXIMUM 1 working day.

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18.3 The table below gives an overview of the minimum training qualifications for the Worker(s) and the Pfizer Approver.

Type of work Worker(s) Pfizer Approver

Work on a live electrical installation (> 50V) BA5

Work in the vicinity of a live electrical connection

BA5

Work on high-voltage installations BA5 + additional training on high-voltage installations

Mechanical work within a 1-meter radius of live high-voltage cables

Must be determined in consultation with the Pfizer

Approver

BA5 + additional training on high-voltage installations

Applicable / N/a Chapter 19 LOCK-OUT-TAG-OUT PROCEDURE

19.1 Work may NEVER be done on MOVING PARTS, LIVE INSTALLATIONS OR EQUIPMENT UNDER PRESSURE without the explicit and written authorisation of Pfizer.

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19.2 EACH CONTRACTOR MUST HANDLE LOCKING FOR ITSELF. This means that if multiple parties are working on the same machine / installation independently of each other, each of them must lock the machine to prevent restarting. The use of MULTI-LOCK PLATES can be a help here.

19.3 Locking should be done with PERSONAL PADLOCKS. The locks used, however, must always be clearly identified (company name, name & telephone number of the person who attached the lock).

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19.4 If no other solution is possible, the following LOCKING TAGS may be used. These locking tags are available from the Pfizer site supervisors. The use of these tags need to be approved by the Pfizer responsible on the work permit.

19.4 The REMOVAL OF LOCKS OR LOCKING TAGS BY UNAUTHORISED PERSONS will result in IMMEDIATE DISCIPLINARY ACTION.

19.5 If it is NOT POSSIBLE to perform the task with a LOCK, the RED TAG PROCEDURE must be used by the person who will be performing the work:

• If a red tag is already present for another task, please contact the supervisor

• Perform a risk assessment with the work manager

• Demarcate the zone

• Fill in the red tag(s) for “Unsafe situation” and have it/them signed by the work manager.

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• Install the red tag visibly at the entrance(s) to the demarcated zone and at the place where the dangerous situation is.

o The contractor determines who is adequately informed / skilled to safely work in the danger zone

o The contractor will inform these people of the unsafe situation

o The contractor will note on the red tag the names of ALL people who have access to the danger zone

19.6. Blue tags are used when equipment is “in validation”.

19.7 White tags are used for infomation, they may not be used if there are any possible risks to unsafe situations.

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ALWAYS APPLICABLE Chapter 20 PERSONAL PROTECTIVE EQUIPMENT (PPE)

20.1 The following PPE must ALWAYS be worn at the work site:

• Safety helmet

• Safety shoes (with steel toe and steel soles)

• Safety glasses

• Work clothing (long pants and outerwear)

• High visibility vests

• Safety gloves (except when works are performed with rotary equipment – see 20.6)

20.2 EXCEPTIONS to this are only possible with the formal authorisation of Pfizer. These will be documented on the work permit or indicated on site.

20.3 In function of the risks associated with the work to be performed, the WORK PERMIT can impose ADDITIONAL PPE.

20.4 It is the RESPONSIBILITY OF EACH CONTRACTOR to make the PPE that is prescribed in the work permit available to its workers / visitors / subcontractors, and to ensure that it is used correctly.

20.5 Each contractor will ensure that the PPE is in GOOD CONDITION and INSPECTED if legally required (see chapter 6).

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206 In certain cases, the use of (safety) clothing and PPE can entail additional risks because they can become caught in the tools used. Consequently, it is PROHIBITED TO WEAR GLOVES AND OTHER LOOSE OR WIDE-FITTING OUTERWEAR while operating DRILLS and CIRCULAR SAWS.

Applicable / N/a Chapter 21 COLLECTIVE PROTECTIVE EQUIPMENT (CPE)

21.1 Based on the prevention principles of the Social Welfare Act, PREFERENCE MUST BE GIVEN TO THE USE OF COLLECTIVE PROTECTIVE EQUIPMENT (guards, safety nets…) over personal protective equipment.

21.2 Locations where a fall hazard exists (openings in ceilings, pits, non-walkable ceiling areas,…) must be closed off or protected by guards that are not easy to remove/move. Temporary closed openings (using panels) should have an sign on top (available @ Pfizer Engineering safety supervisor)

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21.3 If protective slats or scaffolding material is used for protection, the guardrail must be placed at a height of 1 - 1.2 m. The intermediate slat must be located at a height of +/- 0.45 meter. There must also be a baseboard of min. 0.15 m.

21.4 Deviations in the use of the intermediate slat and baseboard must be requested and approved in advance by Pfizer.

21.5 The INSTALLATION AND/OR REMOVAL OF CPE must always take place in DIALOGUE with the SITE SUPERVISORS.

21.6 TEMPORARILY INSTALLED CPE must always be retained and may NEVER BE REMOVED BEFORE DEFINITIVE CPE OR OTHER EQUIVALENT PROTECTIVE EQUIPMENT is installed.

21.7 Locations where a fall hazard exists (openings in ceilings, pits, non-walkable ceiling areas,…) must be closed off or protected by guards that are not easy to remove/move.

21.8 The use of modular fencing (e.g. Heras fencing) is permitted as permanent protection only to the extent that it is secured against unauthorised moving. This can be done for example by connecting the fences to each other and attaching them to a permanent structure.

21.9 If a fall hazard zone cannot be protected by fixed guards, this should be reported immediately to Pfizer. In this case, by way of exception, it may be permitted to protect the zone with double barrier fencing mesh. The first barrier fencing is placed at the edge of the danger zone. The second fencing is placed as an additional barrier 2

Mobile fence foot Mobile fence

Anti-lift device

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meters around the first fencing. Both of these barrier fences must be equipped on all sides with the appropriate Signs that indicate the zone's danger and any required PPE. The use of a single barrier tape to protect zones with a falling hazard is NOT allowed. In case a double barrier fencing mesh is used, a permanent watch need to be present at the opening.

21.10 All temporarily placed collective protection must be equipped at regular intervals with the appropriate Signs.

21.11 Removing collective protection may only take place with the consent of the person who had the protection installed (cf. name on the sign).

Applicable / N/a Chapter 22 SIGNALISATION

22.1 If a zone must be (completely) closed to unauthorised persons, use must be made of adapted signalisation Signs which indicate the risks. All temporary arrangements (fixed guards, barrier fencing, barrier tape,….) for closing off a zone must be equipped with adapted Signs (available at Pfizer Engineering).

22.2 These signs must make it clear to all the reason for closing off the zone (in other words, the hazard). The sign must also indicate the contact information of the person who had the zone closed off. The date of installation as well as the anticipated period of validity of the demarcation must be included on the sign. The sign must indicate whether a general entry ban applies to the zone or whether the zone is subject to restricted access.

22.3 The signalisation sign must be placed at all accesses to the risk zone. In the case of large enclosed zones, signs must be installed at regular intervals so that they can be easily consulted.

22.4 The signalisation must be placed in visible locations, and protected against (weather) conditions that would make the information on the sign illegible.

22.5 The Signalisation does not prohibit the use of Pfizer in-house signalling and other signalling.

Types of signalling Description of use, see section…

Construction site sign 9.3

On-site road signs 10

Signs concerning the general rules of conduct 11

Zones with an explosion hazard 14

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Enclosed spaces 15

Work on fire safety systems 16

Lock tag 19

Tag for dangerous situations 19

Scaffolding inspection card 25

Non-walkable zones 27

Fire safety and alarm 40

Evacuation 41

22.6 Single barrier fencing or tape may not be used to close off zones.

22.7 All loose structures that are temporarily placed/erected at a construction site (e.g. STRUTS, SUPPORTS, ACCESS LADDERS, TEMPORARY WORK PLATFORMS,…) must be identified. The IDENTIFICATION must contain the following information:

* Name and phone number of the person who had the structures installed

* Date of installation

Applicable / N/a Chapter 23 WORKING AT HEIGHT

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23.1. Where elevated work/ work at height can not be avoided, the following hierarchy of controls should be followed

Applicable / N/a Chapter 24 AUTOMATED EQUIPMENT FOR WORKING AT HEIGHTS (AERIAL HOISTING EQUIPMENT, SCISSOR LIFTS…)

24. 1 AERIAL HOISTING EQUIPMENT, SCISSOR LIFTS or other work equipment for working at heights are subject to LEGAL INSPECTIONS (see chapter 6) and be suitable for the working environment (e.g. ATEX zoning). Use of cages in which people are lifted by forklift and open lift systems are prohibited.

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24.2 The users of this work equipment must have received the APPROPRIATE TRAINING (see chapter 5).

24.3. It is forbidden to stand on the railings of the aerial work platform or scissor lift to perform work.

24.4. Ensure that the loading capacity of the aerial work platform, scissor lift or other work equipment for work at heights is never exceeded.

24.5. When using scissor lifts, aerial work platforms and safety cages that are hoisted on high, PERSONAL FALL PROTECTION must always be used (harness, stopdrop tooling, shock absorber). For CONSTRUCTION SITE ACTIVITIES, the standard required personal protective equipment (helmet, safety shoes and safety goggles) must also be worn. For NON-CONSTRUCTION SITE RELATED ACTIVITIES (such as in the warehouse or production), at least safety shoes, safety glasses, bump cap/helmet and a harness must be worn.

24. 6 In operational / production zones, the area around an aerial work platform / scissor lift must always be DEMARCATED WITH FENCES. This is intended to prevent FALLING OBJECTS from injuring bystanders, and other internal means of transport (reach trucks, BTs,…) from COLLIDING with the aerial work platform / scissor lift. At construction sites, this also applies to stationary work from an aerial work platform/scissor lift. For mobile work at construction sites from a scissor lift/aerial work platform, demarcation of the work zone must be examined based on the risks, and the use of separate pedestrian zones must be considered.

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24.7 Scissor lifts, aerial hoisting equipment may NOT be used TO HOIST/LIFT LOADS, which are situated outside the cage. Exceptions are only allowed when there are no other options available. In that case, the contractor should provide a risk analysis to prove the work method and used equipment don’t add additional risks and are suitable for the works to be executed. The safety precautions provided by the manufacturer should be followed/implemented at all times. The risk assessment should be added as an attachment to the work permit.

24.8 EXERCISE CAUTION for possible SUSPENDED ELECTRIC CABLES!

24.9 When using automated work equipment for work at heights, account must be taken of the safety requirements below.

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24.10. A mobile aerial work platform may only be moved when the platform is at its lowest point. Those operating the device must dismount from the platform if the aerial work platform/scissor lift needs to be moved through an area with limited height/width.

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Applicable / N/a Chapter 25 USE OF SCAFFOLDING, MOBILE STAIRWAY TOWERS

25.0 Installing, changing, tearing down and approving (mobile) scaffolding and stairway towers on the Pfizer company premises may only be performed by a specialised scaffold builder appointed by Pfizer. Contractors who for the execution of their duties wish to make use of (mobile) scaffolding or stairway towers must request this from Pfizer sufficiently in advance. However, it is the contractor's responsibility to provide the scaffold builder with sufficient information concerning the exact location where the scaffolding is to be built as well as the expected maximum scaffolding load.

25.1 When scaffolding is being constructed, account must be taken of the risks to individuals and materials that might be located under this scaffolding while it is being built, used and disassembled. The appropriate measures need to be taken to minimise the risks.

25.2 All scaffolding higher than 2 metres must be equipped with GUARDRAILS, CROSS BRACING AND SKIRTING. The work platform must be continuous, i.e. without dangerous gaps between the boards, no free boards, and the guardrail, and sturdy enough for the loads to be carried.

25.3 Scaffolding must be properly secured or anchored when people are working on the scaffolding.

25.4 ACCESS TO THE WORK FLOORS on (mobile) scaffolding is done via STAIRWAY (towers) or LADDERS that must be fitted on the inside of the scaffolding structure. Deviations are only allowed after approval by Pfizer (Safety Department).

25.5 Scaffolding that is 3 times higher than the smallest base must be secured against TIPPING.

25.6 The scaffolding must be inspected by an authorised person before initial use, after modification, and at regular intervals (AT LEAST EVERY WEEK).

25.7 Approval of the scaffolding must be indicated on the scaffolding using a SCAFFOLDING INSPECTION CARD. The same applies to mobile stairway towers and walking platforms. The scaffolding inspection card must contain at least the following information:

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• owner of the scaffolding, • name of the authorised scaffolding inspector, • date until inspection is valid, • max. permitted scaffolding load, • and the indication that the scaffolding must be re-inspected at least every 14 days and after each modification.

25.8 The scaffolding inspection card must be placed in a holder or SCAFFTAG. In the case of removal of the scaffolding inspection card, a text must be visible that clearly indicates that the SCAFFOLDING MAY NO LONGER BE USED because it is still being installed, is no longer safe, or is overdue for inspection.

25.9 Each employee who works on scaffolding, climbs scaffolding or inspects scaffolding must have followed SUITABLE TRAINING (see Chapter 05).

25.10 Scaffolding must be assembled according to the instructions of the manufacturer. For Modular scaffolding (e.g. ALU self-build scaffolding), the ASSEMBLY and DISASSEMBLY DIAGRAM for the scaffolding must be present on the scaffolding at all times.

25.11 For FIXED SCAFFOLDING AND MOBILE STAIRWAY TOWERS BUT ALSO FOR SCAFFOLDING THAT CANNOT BE ASSEMBLED ACCORDING TO THE INSTRUCTIONS OF THE MANUFACTURER, a CALCULATION NOTE must be drawn up. CALCULATION NOTES FOR FIXED SCAFFOLDING must ALWAYS BE PRESENT ON SITE. The calculation notes must be communicated to all contractors who use the scaffolding.

25. 12 MOBILE SCAFFOLDING is a special type of scaffolding and thus must comply with the general regulations applicable to scaffolding.

25.13 The drawings below give an overview of some important safety concerns when using mobile scaffolding.

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25.14 If scaffolding must be used in zones in which work is frequently done with internal means of transport, the zone around the scaffolding must be DEMARCATED WITH SAFETY TAPE and equipped with custom Pfizer Standard Signs (see chapter 20.b). This must prevent internal means of transport (reach trucks, BTs…) from colliding with the scaffolding. During build up / break down of the scaffolding, the impacted area around should be delimited.

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25.15 The performance of some work may require the installation of SPECIAL / COMPLEX SCAFFOLDING . After completion of the work, it is advisable to have the complex scaffolding disassembled as quickly as possible or to prevent unauthorised use thereof by permanently blocking access to the scaffolding and indicating this fact.

25.16 In some cases, it is possible that a scaffolding must be used that IS NOT EQUIPPED WITH A GUARDRAIL (e.g. limited distance between work platform and ceiling). In this case, in consultation with the Pfizer supervisor, an assessment can be made concerning whether the scaffolding may still be used in combination with the use of personal fall protection. If it is deemed that this method can be used safely, it must be very clearly indicated on the work permit and on the scaffolding itself that the SCAFFOLDING MAY ONLY BE USED IN COMBINATION WITH PERSONAL FALL PROTECTION. Account should be taken of the considerations contained in 25.3. 25.17. Fall protection must be worn when performing work from a (mobile) scaffolding whose reach is beyond the perimeter of the scaffolding or when moving from a scaffolding to a fixed structure. 25.18 (Mobile) scaffolding must be kept clean at all times, with a minimum of materials being stored. Materials may not be stored vertically on scaffolding when the scaffolding is not secured. 25.19. For (mobile) scaffolding that is used outdoors, an appropriate procedure must be available that includes restrictions in the case of weather conditions.

Applicable / N/a Chapter 26 USE OF LADDERS

26.1 Ladders must in the first place be used to BRIDGE DIFFERENCES IN HEIGHT.

26.2 Ladders, stepladders and platform ladders may be used as a platform to work at heights for BRIEF TASKS with a LIMITED RISK. If longer periods must be worked at heights or risky work must be performed at heights, other work equipment (scaffolding, aerial work platforms…) must be used.

26.3 Before using stairway or landing ladders, the following safety measures must be taken into account.

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The use of sliding or straight ladders is only permitted only under the following conditions

• As the last option to carry out work at height (no safer alternatives available)

• In the case of works of short duration (less than 30 minutes)

• When tasks are low risk, with the risk analysis showing that alternatives are not a viable option (work permit = risk analysis).

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26.4. A-frame ladders may not be used as a straight ladder. A-frame ladders must be fully opened before use. When using the ladder, both feet must be located on its operational side.

26.5 The use of sliding or straight ladders is permitted only under the following conditions

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Additional considerations when using a ladder:

• The ladder must be in accordance with design standards and legal requirements. • The correct type of ladder must be chosen for the task (height, load capacity, construction material,…) • Before use, the ladder must be inspected for damage and functionality. In this, the following risk criteria must be taken into account:

o Condition of the ladder (damage?) o Age o Rating of the ladder: suitable for the task to be carried out, taking into account the weight of the materials and of the person who will use the ladder.

Recommended rating = EU - Min Class EB131 (SWL 150 kg)

26.6 Overshoes must be removed before climbing a ladder.

26.7 The use of ladders for the execution of mechanical work near (<1 meter) (high voltage) power supply cables need to be evaluated as part of the electrical work permit.

26.8 If tools must frequently be used on a ladder and/or the ladder must be placed in a busy area, the zone around the ladder must be DEMARCATED and an appropriate sign needs to be in place. This is to prevent FALLING OBJECTS injuring bystanders, and people or internal means of transport (reach trucks, BTs…) from colliding with the ladder.

Applicable / N/a Chapter 27 WORKING ON ROOFS

27.1 Work may be done on roofs only after the CARRYING CAPACITY of the roof has been checked in function of the work to be performed. This carrying capacity needs to be mentioned on the work permit.

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27.2 If work must be done WITHIN 4 METRES OF A ROOF EDGE that is not equipped with a permanent guardrail at least 1.2 METRES HIGH OR an OPENING IN A CEILING OR ROOF, COLLECTIVE PROTECTION (guards, safety net) must be used or use must be made of suitable PPE.

27.3 SAFETY NETS may ONLY be installed by SPECIALISED FIRMS.

27.4 NEVER HOIST HEAVY LOADS ABOVE SAFETY NETS.

27.5 IT IS PROHIBITED TO STAND OR LEAN ON SMOKE DOMES / SMOKE HATCHES. They are unable to bear the weight of a person. Non-load bearing structures (e.g. smoke domes) must be identified using the icon above.

27.6 If work must be done on ceilings, the carrying capacity of the ceilings must be verified prior to performing the work. The zone where the work will be done must be indicated on a MAP and included as appendix TO THE WORK PERMIT.

27.7. If OPENINGS in roofs, ceilings or floors must be made, they must ALWAYS be covered, such that they are WALKABLE. The cover needs to be identified using following sign:

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If this is NOT POSSIBLE, all access routes to the non-walkable zone (openings) must be blocked using COLLECTIVE PROTECTIVE EQUIPMENT (guardrails). If these are covered with materials that are not walkable for (quality) reasons, the RISK OF FALLING must be clearly IDENTIFIED AT ALL ACCESS ROUTES TO THE ZONE. The name and telephone number of the person responsible for having this protection installed must also be indicated. In addition, EACH INDIVIDUAL NON-WALKABLE COVERING must be fitted with SIGNS that indicate the BAN ON ACCESS.

27.8 If walkable floors must be (temporarily) opened or ducts made, a request must be made at least the day before for a general permit specifically issued for this purpose. The Pfizer entity commissioning the work can, according to the specific working conditions, decide to have the work performed under the supervision of a standby person. The executors of the work must always wear personal fall protection. All accesses to the zone where the floors have been opened up or ducts are being installed must be closed off with fixed guards and the appropriate signalisation. The validity of the above work permit must be limited to 1 working day. Upon returning the work permit at the end of the working day, Pfizer as commissioning authority, together with the manager of the person performing the work, must consult on site to verify whether the work zone is safe to leave (floor slabs replaced and baseboards reinstalled, guards back intact,…).

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Applicable / N/a Chapter 28 USE OF PERSONAL FALL PROTECTION

28.1 PERSONAL FALL PROTECTION may only be connected to an APPROVED (or sufficiently solid) ANCHOR POINT and/or AFTER CONSULTATION WITH PFIZER

28.2 BAN on HIP BELT as personal fall protection. OBLIGATORY use of HARNESS as fall protection.

28.3 Users must be 100% PROTECTED AGAINST FALLING. While using fall protection, AT LEAST 1 OF THE 2 HOOKS must ALWAYS be ATTACHED to the connection point.

28.4 When using PERSONAL FALL PROTECTION, account must be taken of the following safety aspects.

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28.5 Persons required to wear fall protection must be trained its use.

Applicable / N/a Chapter 29 WORK ON & USE OF ELECTRICAL INSTALLATIONS

29.1 WORK MAY NEVER BE DONE WITH POWER APPLIED.

The distance to an accessible, i.e. not IP2X or finger-safe, piece of conductor that is under power, in which a body part or a tool is to be introduced, determines whether the work is conducted under, in the vicinity of, or outside the high voltage zone. The zone under power is called the touch zone (red circle) and the zone in the vicinity of the voltage (blue circle) is called the proximity zone. The distances that determine these zones depend on the voltage on the accessible conductor

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Below In the proximity of Outside

50-500 V AC <2.5 cm 2.5 cm < ….< 1m >1m

500-15000 V AC <20 cm 20 cm < ….< 3m >3m

29.2 In order to WORK WITHOUT ELECTRICITY APPLIED, the following 7 ESSENTIAL STEPS must be followed:

1. Work preparation (e.g. locate the correct electrical diagrams)

2. Switching off (e.g. turn off main power switch, remove from electrical outlet)

3. Lock (e.g. place lock on main power switch – see chapter 22)

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4. Test / Measure

5. Earth (required in the case of high voltage and in the case of low voltage when there is a risk of induced voltages)

6. Isolation of the zone / isolation of parts that are still live

7. Release of the work

29.3 Work on electrical systems / installations may ONLY be performed by duly TRAINED PERSONS (BA4 / BA5 – see chapter 5).

29.4 For the following work, a SUPPLEMENTARY ELECTRICAL WORK PERMIT must be requested and obtained:

1. All work ON HIGH-VOLTAGE INSTALLATIONS

2. All work in the VICINITY OF HIGH-VOLTAGE CABLES

2. Work on LIVE INSTALLATIONS

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3. Work in the VICINITY OF NON-ISOLATED ELECTRICAL INSTALLATIONS (e.g. measuring in a BA5 panel)

29.5 All TEMPORARY ELECTRICAL INSTALLATIONS must be APPROVED beforehand by a certified technical inspection firm (see chapter 15). It is not sufficient to certify panels or distribution boards in the warehouse. The entire installation (connectors, cabinets, cables, connections, electrical generators, earth conductor …) must be certified on site.”

29.6 DISTRIBUTION PANELS must ALWAYS REMAIN CLOSED.

29.7 All connections (PLUGS / POWER OUTLETS) must be suited to use in A DAMP ENVIRONMENT MINIMUM IP44. The mechanical resistance of the cables at the construction site must be compatible with the conditions of use. At a construction site, only cables of the type H07RN-F, CTMB-N, CTFB-N or equivalent cables may be used. In practice, the diameter of the wiring to which a power outlet is connected must be at least 2.5 mm². A diameter of 1.5 mm² is only allowed for the connection of lighting equipment.

29.8. Electrical supplies for industrial applications need to be produced according to the European Standards and need to have a CE label.

29.9 When extension cables are used, the cable must be completely unwinded before use.

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29.10 CABLES must ALWAYS BE SUSPENDED and/or protected against possible damage.

29.11 DAMAGED CABLES must be removed and replaced immediately.

29.12 PFIZER will take care of the GENERAL AISLE AND EMERGENCY LIGHTING. EACH SUBCONTRACTOR is responsible for LIGHTING ITS OWN WORK AREAS. The lighting must implemented according to the applicable regulations.

29.13 Only the Pfizer Utilities department is allowed to connect or disconnect the Electrical cabinets from the Pfizer power distribution net.

29.14 CABLES TAKEN OUT OF SERVICE MUST BE REMOVED IMMEDIATELY! = PROFESSIONALISM

29.15 If a cable cannot be removed immediately, the following is REQUIRED: Step 1: Disconnect the cable (without power) from its power source

Step 2: Remove a bit of insulation from the other end of the cable

Step 3: Twist the copper wires together (= twist wires around each other)

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Step 4: Protect the free end of the cable with a wire nut/insulating tape

Step 5: Attach a lockout tag to the cable end.

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The twisting together of the copper wires is an additional safety measure that supplements disconnection of the cable. In the case of unauthorised switching on the circuit, this causes a short circuit and the fuse will blow immediately. However, this procedure should only be applied in exceptional cases. The rule remains that cables should be removed immediately after being taken out of use. This therefore must be systematically verified at the end of the work/project acceptance.

29.16 If a cut-through cable is discovered that is not equipped a wire nut or insulation tape and tag, it should NEVER be touched, measured or removed. Create a safe zone around the cable and immediately notify your Pfizer contact of the dangerous situation. This person is obliged to inform the Pfizer Utilities Department, which will take the appropriate action to safely take the cable out of service.

29.17 New electrical cables which need to be connected need to be provided with a protective tape at all sides which are not connected.

Applicable / N/a Chapter 30 HOISTING AND LIFTING LOADS

30.1 All hoisting and lifting devices used must pass LEGAL INSPECTION (see chapter 6).

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30.2 Hoisting activities may only be performed by AUTHORISED PERSONNEL (also for hoisting of non critical loads) (see chapter 5).

30.3 Each contractor must take the required measures to guarantee the STABILITY of its hoisting and lifting equipment (as well as the other equipment). For this, it will consult the GROUND STUDY, UTILITY LINE MAPS… If the stability of the ground is inadequate, OUTRIGGER PADS OR STEEL RAMPS must be used in order to ensure safe deployment of the lifting equipment.

30.4 The working environment must be properly VISIBLE to the operator (install additional lighting if necessary). Communication between operator and RIGGER must be guaranteed. Additional means of communication must be foreseen if needed.

30.5 If MULTIPLE LIFTING DEVICES WITH OVERLAPPING BOOMS are used (at one or contiguous construction sites), a procedure must be drawn up in consultation with the safety coordinator(s) responsible for project execution.

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30.6 For LARGE AND CRITICAL LOADS, such as loads with an irregular shape, such that the centre of gravity is difficult to determine, a lifting plan will be drawn up before execution of the hoisting operation. This lifting plan will be submitted for approval to the contracting authority and safety coordinator before start of the work. The lifting plan contains at least the following information:

* The weight and centre of gravity of the load

* The procedure for securing the load

* The set-up of the crane

* Delivery and removal of the load

* Check for the presence of underground pipes and/or obstacles

* Ground pressure (up to 10 tonnes/m²)

* Check for the presence of power lines

* Procedure for communication between the rigger and crane operator

* Qualification information for crane operator and rigger

30.7 NEVER HOIST ABOVE PERSONS OR ZONES THAT ARE IN USE. The zones where the hoisting will be done must be CLOSED OFF during the hoisting work and appropriate signalisation need to be installed.

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30.8 ALWAYS DOUBLY SECURE HEAVY LOADS.

30.9 The RIGGER needs to be clearly recognizable (eg orange fluo jacket). When lifting works are started, a clear signal must be given by the rigger.

30.10. HOISTING BELTS used must always be APPROVED (even when lifting non-critical loads). This must be VISUALLY APPARENT to the user.

Applicable / N/a Chapter 31 EXCAVATION WORK

31.1 ALWAYS CONSULT THE MAPS BEFORE BEGINNING TO DIG. Plans that need to be consulted are:

• Internal floor plans at Pfizer (via Pfizer contact person)

• the plans requested via the KLIP portal (requested by the contractor in question at least 2 weeks prior to the start of work).

31.2 The available floor plans must be present on site with the work permit.

31.3 At the start of excavation works for the purpose of repair or changes to underground cables or pipes, it is necessary to clearly identify the cable or pipe beforehand

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31.4 When excavation work must be done by means of cranes, backhoes or other mechanical equipment, exploratory excavations will first manually be made around the construction site with a flat shovel or mechanically with a sand sucker. This is to locate and mark underground lines. Only when complete certainty prevails concerning the existing pipes/cables can use be made of excavation equipment. The exploratory trenches must be at least 20 cm deeper than the pit to be dug mechanically

31.5 Within a radius of 1 METRE AROUND UNDERGROUND PIPING/ELECTRIC CABLING, only MANUAL EXCAVATION may be done. This boundary indication must always be conspicuously attached to the site of the work.

31.6 Excavation work near live electrical cables may only be carried out by BA4 qualified workers with an electrical work permit.

31.7 Excavation work close to UNDERGROUND GAS LINES must be REQUESTED FROM the GAS NETWORK MANAGER beforehand.

31.8 Excess groundwater will always be removed in order to ensure maximum visibility during the excavation work to be carried out. This can be done by ground dewatering and/or pumping. Ground dewatering requires a permit and this must be requested and discussed with the Pfizer EHS/environment department during the design phase.

31.9 Upon discovering unidentified pipes/cables or in the case of damage to the piping/cables, work must be stopped immediately. The work may be resumed only after approval by the responsible Pfizer manager

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31.10 the use of a concrete or stone saw and the use of mechanical excavators is allowed when dealing with a hardened/hard top layer, but is FORBIDDEN within a 1 meter zone around a location where electrical or instrument cables disappear below ground level. All mechanical work within a perimeter of 1 meter around the cable may only take place when the POWER HAS BEEN REMOVED. If power cannot be removed, an electrical work permit must be requested.

31.11 All excavated cables and piping must always be sufficiently supported to prevent damage. The cables must be prevented from sagging.

31.12 When working with a mechanical shovel, bulldozer or other mechanical excavator or excavation equipment, no one may enter the outer turning radius, + the length of one man, from the boom and the machine.

31.13 When re-filling excavations, sufficient attention must be paid to compaction of the ground layers.

31.14 High-voltage cables and cables not locally fused must be equipped with physical shielding before filling in.

31.15 The impact of excavation work on the internal traffic plan must be assessed during preparations. In consultation with the appropriate Pfizer manager, the necessary alternative routes/accesses must be provided for and indicated.

31.16 All excavations must be surrounded by fencing (fixed rails). By exception for excavations < 2 meters deep the Pfizer responsible can give permission to use nets. IN this case it must first be equipped with fixed rail barrier fencing mesh at least 1 meter from the edge of the pit and a 2nd orange barrier fence 1 meter from the first fence. Excavations deeper than 2 meters must always be equipped with fixed rails at least 1 meter from the edge of the pit.

31.17 All excavations greater than 1.20 meters deep and whose sides have a slope steeper than 4/4 (45°) (base/height) must always be equipped with an appropriate support wall for the entire circumference to prevent the excavation from caving in. Also, a sufficient number of ladders must be placed in the pit to allow all the possibility of rapid evacuation.

31.18 For depths > 1.2 meter, excavation work must be considered as risky. With respect to supervision, this means that during the excavation work, there must always be at least 1 person outside the excavation area. This person may be working, but must always maintain eye contact with those performing the excavation work (see work permit item 8.16)

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Applicable / N/a Chapter 32 STORAGE AND USE OF DANGEROUS SUBSTANCES

32.1 Hazardous products must be properly LABELLED.

32.2 The use of hazardous products must be REPORTED TO PFIZER BEFOREHAND by submitting the MSDS (material safety data sheet) for the product to Pfizer.

32.3 The HEALTH AND SAFETY MEASURES (e.g. PPE) PRESCRIBED in the material safety data sheet must always be respected.

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32.4 Hazardous products must be safely STORED according to the relevant legal regulations. All hazardous liquids must be stored in a DOUBLE-WALLED CONTAINMENT FACILITY OR ABOVE A DRIP TRAY. The containment facility must be able to handle the maximum volume of stockpiled liquid.

32.5 The ASBESTOS present has been inventoried and indicated with pictograms. If asbestos is detected that has not been indicated, this must be reported to Pfizer immediately. REMOVAL OR MECHANICAL DAMAGE TO ASBESTOS IS STRICTLY PROHIBITED AND MAY ONLY BE PERFORMED BY SPECIALISED FIRMS.

32.6 The use of IONISING SOURCES (e.g. thickness measurements) must ALWAYS be REPORTED beforehand. All access to the work areas where work is being done with ionising sources must be sealed and equipped with the appropriate Signalisation Signs - general entry ban.

Applicable / N/a Chapter 33 USE OF KNIVES

33.1 Use of knives with blades that do not retract automatically are not allowed.

.

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33.2 ALLOWED KNIVES (automatically retracting blades)

33.3 Other types of knives are only allowed after approval by Pfizer EHS department / safety supervisors and the use of additional PPE (gloves)

33.4 Knives with no automatically retractable blade (eg Stanley) may not be left behind unprotected. This means that the knife must be retracted or stored in a blade holder after each use. It is NOT ALLOWED to store unprotected knives in clothing or storage boxes.

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Applicable / N/a Chapter 34 DEMOLITION WORKS

34.1 before start of demolition works, a detailed execution plan need to be prepared (day by day works, drawing available, attached to work permit). This execution plan need to be reviewed and formally approved by a structural engineer.

34.2 during execution of the works, the execution plan need to be revised/reviewed periodically (daily) and followed stricktly. Daily approval by the structural engineer is obligated.

Applicable / N/a Chapter 35 CONTROL OF DUST EMISSIONS DURING CONSTRUCTION, DEMOLITION AND INFRASTRUCTURE WORKS

35.1 From 1 January 2017, contractors are obliged to minimise dust emissions from construction, demolition and infrastructure works. The regulations apply to all construction, demolition and infrastructure works carried out in the open air by a contractor that take longer than one day.

35.2 There are four specific measures required to prevent dust emissions coming from razing work, sandblasting, polishing, grinding, drilling, milling, sawing and demolition. At least one of these four measures must be taken. These measures are:

(1) Protection with cloth or tarps,

(2) Misting of the location where work will be performed,

(3) Wetting the area round the equipment,

(4) Direct dust extraction on demolition hammers, polishers, grinders, drills, milling machines and sanders. Additionally there must be misting or wetting when doing demolition work under dry or windy conditions in which dust dispersal visually occurs.

35.3 The installations must be maintained and inspected, and dust filters must be replaced in a timely manner.

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Applicable / N/a Chapter 36 STORAGE AND REMOVAL OF SOIL, RUBBLE AND DEBRIS

36.1 STORAGE OF WASTE, SOIL AND DEBRIS may only be done in ZONES DESIGNATED for this in the site organisation map. The materials must be stacked in the zones provided in an ORDERLY AND STABLE WAY, AND PROTECTED AGAINST THE WEATHER.

36.2 EXCAVATED GROUND may only be removed from the site according to the legal regulations related to SOIL TRANSPORT and in consultation with Pfizer.

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ALWAYS APPLICABLE Chapter 37 REMOVAL AND TRANSPORT OF (HAZARDOUS) WASTE

37.1 Depending on the TYPE OF WASTE (domestic waste, industrial waste, small hazardous waste, wastewater, scrap material, etc.) the contractor, in accordance with the applicable regulations, shall PROPERLY TRANSPORT THESE MATERIALS and if applicable SUBMIT PROOFS OF THEIR TRANSPORT to an APPROVED DUMPING SITE OR TREATMENT SITE as well as the PROOFS OF TREATMENT (one copy is submitted to the environmental department for inclusion in the site dossier).

37.2 HAZARDOUS WASTE must always be identified in accordance with the legal regulations (PRODUCT NAME AND DANGER ICONS).

37.3 Hazardous products may NEVER be poured into SEWERS!

37.4 The INCINERATION OF WASTE at the construction site is PROHIBITED.

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ALWAYS APPLICABLE Chapter 38 ORDER AND NEATNESS

38.1 At least once DAILY, each contractor must CLEAN ITS WORK AREAS AND REMOVE WASTE.

38.2 ROADS, AISLES AND STAIRS must always be FREE of OBSTACLES AND HINDRANCES. Cables may not obstruct passage.

38.3 The STORAGE OF MATERIAL such as scaffolding, ladders, cranes, site machinery, etc. must be done in such a way that all entrances, passageways, emergency exits, stairs, etc. remain open and that possible workers from other companies can further conduct their activity in a safe way.

38.4 All MATERIAL WHICH CAN FALL OVER (scaffolding pipes, ….) MAY NOT BE STORED VERTICALLY

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ALWAYS APPLICABLE Chapter 39 ASSISTANCE & MEASURES IN THE CASE OF WORK ACCIDENT

39.1 EACH CONTRACTOR must always have a complete FIRST-AID KIT available at the work site.

39.2 Each work accident must be notified to a qualified FIRST-AID ASSISTANT, indicating the seriousness and location of the accident.

39.3 In the case of a NON-SERIOUS WORK ACCIDENT, the assistant will provide care for the victim, and if necessary refer him/her to the PFIZER MEDICAL DEPARTMENT (03/897-45-55). Pfizer medical personnel will refer the victim to a doctor or hospital if necessary.

39.4 For a SERIOUS ACCIDENT or accidents that require supplementary medical treatment, Pfizer must ALWAYS be contacted via the EMERGENCY

NUMBER: 03/897-45-55. Pfizer will take the measures required to guide the emergency services to the location of the accident.

39.5 In the case of doubts concerning the condition of the victim (for example after a fall from a height and/or risks to the spinal column) DO NOT MOVE THE VICTIM (unless there is immediate danger), but wait for the emergency services or the qualified assistant.

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39.6 EACH ACCIDENT must be REPORTED to the Pfizer site supervisor and the Safety Coordinator. Each accident must be subjected to an accident investigation in consultation with Pfizer.

39.7 For each ACCIDENT WITH WORK STOPPAGE or with greater than average first-aid care (e.g. suture, cast…), the following parties will be invited to participate in the accident investigation:

o Pfizer Safety Department

o Safety Coordinator responsible for Project Execution

o Safety Adviser of the contracting firm

39.8 For accidents for which reports are legally required (SERIOUS ACCIDENTS), the contracting firm in question, in consultation with Pfizer and the Safety Coordinator responsible for Project Execution, must draw up a comprehensive report and submit this on time to the legal inspection services.

ALWAYS APPLICABLE Chapter 40 FIRE

40.1 EACH FIRE must be reported immediately by:

• activating a FIRE ALARM

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• or notification via the EMERGENCY NUMBER 03/897 45 55

40.2 If the EMERGENCY NUMBER is called, please communicate the following information:

• your NAME • the LOCATION of the fire • the SCALE of the fire • whether DANGER is present

40.3 You may attempt to EXTINGUISH the fire on condition that you do not put yourself in danger.

40.4 Because of a higher risk of fire during site activities, a smoke detection and sprinkler needs to be in use from start till finish. In case of deviations: see chapter 16.

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40.5 As long as the construction site has no continuously operational smoke detection system, the project team must foresee monitoring by a fire watch during the construction activities. The fire watch must remain on site for at least 1 hour after the end of the construction activities. The fire watch may not combine his supervisory duties with other operational tasks.

40.6 During construction site activities, there must be at least 1 fire extinguisher (powder or foam 6 kg) per 150 m2 at strategic locations on site. If no sprinkler protection is active, all points on the site must be accessible with fire hoses. If this is not the case, at the start of the construction site, the project team must provide sufficient extra fire hoses (type DSP45, length 25 m) and associated fire nozzles to make fire extinguishing water from nearby compartments available at all locations at the site.

40.7 The availability and use of fire extinguishers must take account of the (expected) type of fire (fire class).

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ALWAYS APPLICABLE Chapter 41 EVACUATION

41.1 In the case of a FIRE/EVACUATION ALARM (continuous signal / or alarm horn), after securing the workplace, all must proceed to the prescribed EVACUATION MEETING PLACE. The location of the various EVACUATION MEETING PLACES can be found in the map below.

.

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41.2 A count will take place at the evacuation location based on an ATTENDANCE LIST. The names of missing persons must be notified immediately to the Pfizer company intervention team via the emergency number 03/897 45 55.

41.3 The evacuation location may only be left after the END ALARM or after formal permission by the Pfizer managers.

41.4 Following an evacuation, ALL WORK PERMITS EXPIRE. Work may only be resumed after the work permits are re-issued by the Pfizer managers.

41.5 Work is done in certain zones within the company with NITROGEN AND HYDROGEN PEROXIDE. In the event of a leak in small, enclosed areas, these products can result in a hazardous atmosphere (nitrogen -> suffocation and hydrogen peroxide -> internal burns). These zones and the access to these zones are equipped with oxygen and hydrogen peroxide alarms (blue light). If you are IN A ROOM where a BLUE FLASHING LIGHT AND ALARM are activated, LEAVE THIS ROOM IMMEDIATELY and inform the Pfizer manager responsible for this. Rooms where a BLUE FLASHING LIGHT at the ACCESS DOOR IS ACTIVE may NOT BE ENTERED.

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41.6 There is an X-ray producing apparatus (E-Beam) in one of the production rooms (DSF3). This machine does not contain an ionising source. However, the E-beam does produce X-rays when in operation. In consultation with the supplier and the government licensing body, the E-Beam was equipped with diverse protective means (lead housing, protection due to distance,…). These protective measures ensure that radiation exposure to bystanders remains well below the legal limits. While this is not legally required, continuous dosimeters were installed in the room at critical places. If these meters detect an increase in radiation, a visual and audible alarm will be activated. Upon activation of the alarm, the room must be vacated immediately. The instructions to be followed in the case of alarm are hanging in the room and at all entrances to the room. No specific training is required for contractor activities in the room. However, if work is to be performed on the E-beam itself, the workers must have already followed Pfizer in-house radiation training.

ALWAYS APPLICABLE Chapter 42 ORGANISATION OF SAFETY AND HEALTH ON THE CONSTRUCTION SITE

42.1 The SAFETY COORDINATOR is in charge of coordinating the safety and health aspects for the totality of the work, in case a project should meet requirements according to legislation of temporary or mobile construction sites. Agreements between different employers concerning safety and health at the construction site must first be approved by the safety coordinator. The necessary documents for this must be supplied by the contractor firms. This must take place at least 14 days before starting work. The task-specific risk assessments must be delivered in DUTCH and ENGLISH.

42.2 Before the start of the project (and/or before the start of each phase/batch in function of the work), the COMMISSIONING AUTHORITY will organise a KICK-OFF MEETING. All affected contractors and the safety coordinator will be invited to this meeting.

42.3 The COMMISSIONING AUTHORITY will organise a START-WORK MEETING before the start of work with each RESPONISBLE CONTRACOR separately.

42.4 The relevant parties agree to be present at the WEEKLY COORDINATION STRUCTURE MEETINGS.

42.5 EACH CONTRACTOR must hold at least 1 TOOLBOX meeting monthly on a safety topic.

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42.6 EACH CONTRACTOR is required to appoint a SAFETY OFFICER who will be present at the construction site for the full duration of the work.

42.7 All site supervisors must be competent in DUTCH OR ENGLISH, as well as the LANGUAGE spoken by their WORKERS.

42.8 Pfizer is free to invite the safety officer to participate in a SAFETY TOUR at the work site.

42.9 A DAILY SAFETY MEETING will be held at the large construction sites at a time to be announced. At this meeting, the activities of the last 24 hours as well as those of the coming 24 hours will be discussed with respect to safety. Each contracting company is expected have its safety officer present at this meeting.

42.10 Pfizer is free to invite the safety officer to participate in a SAFETY TOUR (Observation of Unconscious Behaviour [OOG] tours) at the work site.

42.11 Contractors are asked to immediately notify perceived dangerous situations to the Pfizer safety supervisor/commissioning authority. The notification will be entered into a tracking system as a “good save” and further followed up. This manner of working is intended to be a proactive safety policy.

36.12The Pfizer contractor safety committee will regularly conduct a contractor evaluation. During this evaluation, the safety performance of the principal contracting firms will be assessed. The evaluation is carried out based on the following parameters:

* Observations recorded during site tours on the reverse side of the permits

* Accidents

* Major incidents

* Documentation required for safety coordination (Safety, Health and Environment [VGA] plan, EHS charter, risk analysis)

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* Number and quality of the reported “good saves”

A Pfizer contractor safety award is periodically awarded based on these evaluations. Companies that (systematically) score low on this assessment or are guilty of serious infringements will be invited for an interview with the aim of drawing up a corrective action plan. If this results in no improvement or if the seriousness of the infringement is of such a nature, this can result in removal of this company from the list of approved contractor companies.

ALWAYS APPLICABLE Chapter 43 CONSTRUCTION SITE INSTALLATION

43.1 For each construction site a logistics plan/site installation plan needs to be provided and approved by Pfizer (remark: this can be part of the constructability plan). 43.2 The construction site needs to have a fixed fence to prevent unwanted visitors 43.3 if the construction site is located within Pfizer buildings, meaning surrounded by production, the site needs to be enclosed using a temporary wooden wall. 43.4 A separated access route needs to be installed for contractor employees to be able to go to the construction site. Site traffic needs to be abandoned from this area. These access routes need to be demarcated with fixed barriers (no tape allowed). 43.5 To define work areas in the construction site, fixed barriers need to be used. Use of safety tape is not allowed. 43.6 Access routes to and from work areas, need to be and remain free from any obstacles and need to be sufficiently illuminated

Applicable / N/a Chapter 44 PROJECT SPECIFIC RISKS

If the project contains specific risks that are not covered in this document, these should be indicated below. There must also be an indication per risk of which security measures will be taken to carry out the work safely.

Nr Project specific risks Safety measures

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ALWAYS APPLICABLE Chapter 45 LIST OF ACTIONS TO BE COMPLETED BEFORE WORK IS BEGUN

Chapter / paragraph no Description of the activity to be performed Action manager Due date

Name of the contracting firm:

Name First name Position Date Signature for approval

Pfizer Representative

Representative of the contracting firm