pharma
TRANSCRIPT
NUTRITION-DRUG
INTERACTION
“A drug is taken to prevent or treat sickness and disease”
Absorption
Distribution
Metabolism
Excretion
How Nutrient-Drug Interaction takes place?
Food(nutrients
)
Used by the body
Energy
Nutrient drug interaction
the body is unable to use a nutrient due to a drug that has been taken
Adverse Effects of Nutrient-Drug Interactions
Some drugs may affect the absorption of nutrients
Some foods, for example, those containing caffeine, can amplify or modify the effects of certain drugs
DRUG
INDICATION
POSSIBLE EFFECTS
COUMADIN
Anticoagulant (blood thinner)
Vitamin K is a nutrient in the body that helps blood to clot
It will interfere with a blood thinner
POSSIBLE EFFECTS
Vitamin K is present in foods such as green, leafy vegetables and fish.
DILANTIN
Anticonvulsant (anti-seizure)
POSSIBLE EFFECTS
Vitamin D and folic acid levels in the body are decreased by taking these types of drugs
NORVASC
Antihypertensive (for high blood pressure)
POSSIBLE EFFECTSConsuming foods high in sodium (i.e., processed meats, canned foods) will decrease the effectiveness of the drug
ASPIRIN
Anti-inflammatory/pain reliever
POSSIBLE EFFECTS
Taking large amounts of these drugs will cause a loss of Vitamin C in the body.
TETRACYCLINE
Antibiotic
POSSIBLE EFFECTS
• Calcium may interact with the effectiveness of the antibiotic.
• Avoid dairy products for two to three hours before and after taking the medicine.
LIPITOR/ZOCOR
Statins (cholesterol-lowering drugs)
POSSIBLE EFFECTS
Antioxidants (Vitamin A, C, E, B, folic acid) may interact with the drug by reversing its effect.
LASIX
Diuretic (water-eliminating)
POSSIBLE EFFECTS
The Drug may decrease appetite thus decreasing
nutrient intake.
Impact of Food on Effectiveness of a Drug
Nutrients in food may either delay absorption into the body or speed up elimination from the body, either or which can impact a drug's effectiveness
The acidic ingredients in fruit juices are capable of decreasing the power of antibiotics such as penicillin
Many medications that are taken to fight depression can be dangerous if mixed with beverages
Impact of Drug on Nutritional Status
Drugs may cause a increase or decrease in appetite, leading to a increase or decrease in nutrient intake
Nutritional status may also be impacted by a drug's effect on the three main nutrients
Carbohydrates
Fat Protein
A drug may speed up or slow down the breakdown of these three nutrients, which are essential to the body's functioning
When a drug affects the absorption of nutrients from food into the body, less energy is available to be used by the body
TIPS FOR AVOIDING INTERACTIONS
Be sure to read the label on a prescription medicine and ask a pharmacist or physician if something is not clear.
Read all directions, warnings, and any possible side effects printed on all drug labels and information in the package
Always take medications with a full glass of water
A drug may not work correctly if a medicine is taken improperly; do not stir medication into food or take apart capsules (unless told to do so).
Contd..
Take vitamin and mineral supplements before or after medicine, as they may interact with certain drugs.
Avoid stirring drugs into hot drinks such as coffee because the drug's effectiveness can be destroyed by the hot temperature.
Do not drink alcohol when taking any medicine.