pharmacology course outline
TRANSCRIPT
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Department: Pharmacy
Course Code: PhBioSci 6
Course Title: Pharmacology and Therapeutics II – Lecture
Course Description:
This course introduces the study of the properties, effects, and therapeutic value of the primary
agents in the major drug categories. Topics include autonomic pharmacology, drugs acting on the
cardiovascular-renal system, central nervous system pharmacology, drugs with important actions
on the smooth muscle, drugs used to treat diseases of the blood, inflammation and gout, endocrine
system pharmacology and chemotherapeutics. Upon completion, students should be able to place
major drugs into correct therapeutic categories and identify indications, side effects, and trade and
generic names.
Course Credit(s): 4 Units – Lecture (3 Units); Laboratory (1 Unit)
Contact Hours: Friday, 3 pm – 6 pm
Pre-Requisite(s): Organic Medicinal and Pharmaceutical Chemistry (Lecture and Laboratory)
Co-Requisite(s): Pharmacology and Therapeutics II – Laboratory
Course Outcomes: Upon completion of this course, the student will demonstrate knowledge of each
of the following:
Major types of drug receptors and the molecular mechanisms of drug action.
Autonomic pharmacology.
Basic and clinical pharmacology of the cardiovascular and renal agents.
Central nervous system pharmacology.
Molecular mechanisms of action and clinical use of smooth muscle acting agents.
Hematologic pharmacology.
Basic and clinical pharmacology of the drugs that regulate inflammation and gout.
Endocrine pharmacology and hormone therapy.
Chemotherapeutics.
MINDANAO MEDICAL FOUNDATION COLLEGE P. Villanueva St., Agdao, Davao City
Tel. No. (082) 221-6225
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Course Content (Outline of Instruction)
1st Preliminary Grading Period – January 6, 2017
SECTION I – BASIC PRINCIPLES
1. Introduction: The Nature of Drugs & Drug Development & Regulation
2. Drug Receptors & Pharmacodynamics
SECTION II - AUTONOMIC DRUGS
6. Introduction to Autonomic Pharmacology
SECTION V - DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM
21. Introduction to the Pharmacology of CNS Drugs
1st Preliminary Examination – January 13, 2017
2nd Preliminary Grading Period – January 20 and 27, 2017
SECTION II - AUTONOMIC DRUGS – January 20, 2017
6. (Review of) Introduction to Autonomic Pharmacology
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs
8. Cholinoceptor-Blocking Drugs
9. Adrenoceptor Agonists & Sympathomimetic Drugs
10. Adrenoceptor Antagonist Drugs
SECTION III – CARDIOVASCULAR-RENAL DRUGS – January 27, 2017
11. Antihypertensive Agents
12. Vasodilators & the Treatment of Angina Pectoris
13. Drugs Used in Heart Failure
14. Agents Used in Cardiac Arrhythmias
15. Diuretic Agents
2nd Preliminary Examination – February 3, 2017
Midterm Grading Period – February 10 and 17, 2017
SECTION V - DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM – February 10, 2017
21. (Review of) Introduction to the Pharmacology of CNS Drugs
22. Sedative-Hypnotic Drugs
23. The Alcohols
24. Antiseizure Drugs
25. General Anesthetics
26. Local Anesthetics
SECTION V - DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM – February 17, 2017
27. Skeletal Muscle Relaxants
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
29. Antipsychotic Agents & Lithium
30. Antidepressant Agents
31. Opioid Agonists & Antagonists
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32. Drugs of Abuse
Midterm Examination – February 24, 2017
Pre-Final Grading Period – March 3, 10, and 17, 2017
SECTION IV - DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE – March 3, 2017
16. Histamine, Serotonin, & the Ergot Alkaloids
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related
Compounds
19. Nitric Oxide
20. Drugs Used in Asthma
SECTION VI - DRUGS USED TO TREAT DISEASES OF THE BLOOD, INFLAMMATION, & GOUT – March 10, 2017
34. Drugs Used in Disorders of Coagulation
35. Agents Used in Dyslipidemia
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs,
Nonopioid Analgesics, & Drugs Used in Gout
SECTION VII - ENDOCRINE DRUGS – March 17, 2017
37. Hypothalamic & Pituitary Hormones
38. Thyroid & Antithyroid Drugs
39. Adrenocorticosteroids & Adrenocortical Antagonists
40. The Gonadal Hormones & Inhibitors
41. Pancreatic Hormones & Antidiabetic Drugs
42. Agents That Affect Bone Mineral Homeostasis
Pre-Final Examination – March 24, 2017
Final Grading Period – March 31, 2017 and April 7, 2017
SECTION VIII - CHEMOTHERAPEUTIC DRUGS – March 31, 2017
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, &
Oxazolidinones
45. Aminoglycosides & Spectinomycin
46. Sulfonamides, Trimethoprim, & Quinolones
47. Antimycobacterial Drugs
48. Antifungal Agents
51. Clinical Use of Antimicrobial Agents
SECTION VIII - CHEMOTHERAPEUTIC DRUGS – April 7, 2017
49. Antiviral Agents
52. Antiprotozoal Drugs
53. Clinical Pharmacology of the Antihelminthic Drugs
54. Cancer Chemotherapy
55. Immunopharmacology
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Final Examination – April 14, 2017
Course Requirement(s):
Perfect Attendance
Textbook (Latest Edition) – Print or Electronic Version
Notebook and Pen
Grading System: (Total: 100%)
Attendance - 10%
Quizzes - 30%
Periodical Exam - 60%
Textbook:
Basic and Clinical Pharmacology
□ Author(s)/ Editor(s): Bertram G. Katzung, Anthony J. Trevor
□ Edition: 13th
□ Copyright: 2015
□ Publisher: McGraw-Hill Education
□ ISBN: 978-0-07-182505-4
Other Reference(s):
Katzung and Trevor s Pharmacology Examination and Board Review
□ Author(s)/ Editor(s): Bertram G. Katzung, Anthony J. Trevor, Marieke Kruidering-
Hall
□ Edition: 11th
□ Copyright: 2015
□ Publisher: McGraw-Hill Education
□ ISBN: 978-0-07-182635-8
Wilson and Gisvold s Organic Medicinal and Pharmaceutical Chemistry
□ Author(s)/ Editor(s): John M. Beale, John H. Block
□ Edition: 12th
□ Copyright: 2011
□ Publisher: Lippincott Williams & Wilkins
□ ISBN: 978-0-7817-7929-6
Goodman and Gilman s The Pharmacological Basis of Therapeutics
□ Author(s)/ Editor(s): Laurence L. Brunton, Bruce A. Chabner, Bjorn C. Knollman
□ Edition: 12th
□ Copyright: 2011
□ Publisher: The McGraw-Hill Companies, Inc.
□ ISBN: 978-0-07-162442-8
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General and Molecular Pharmacology – Principles of Drug Action
□ Author(s)/ Editor(s): Francesco Clementi, Guido Fumagalli
□ Edition: 1st
□ Copyright: 2015
□ Publisher: John Wiley & Sons
□ ISBN: 978-1-118-76857-0
Clinical Pharmacy and Therapeutics
□ Author(s)/ Editor(s): Roger Walker, Cate Whittlesea
□ Edition: 5th
□ Copyright: 2012
□ Publisher: Elsevier, Ltd.
□ ISBN: 978-0-7020-4294-2 Professor’s Detail s : Name: Dex Marco T. Guibelondo, BSPharm 15 (SPC Davao City), RPh 16
Contact No(s): (082) 235-2916; (+63) 921-2097-257
E-mail address(es): [email protected]; [email protected]