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PHENOXYETHANOL

(* = stereogenic center)

3D STRUCTURE

CH3 H

O

OH

STEREOISOMER

Enantiomers

CH3 H

O

OH

CH3H

O

OH

*

7/26/2019 Phen Oxy Ethanol

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ASSIGNING PRIORITIES TO STEREOGENIC CENTERS

i. Enantiomer

CH3 H

O

OH

(2S)-2-PHENOXYETHANOL

ii. Enantiomer !

CH3H

O

OH

(2R)-2-PHENOXYETHANOL

AD"ANTAGE O# !$PHENOXYETHANOL

i. Phenoxyethanol is used as an anti-bacterial in cosmetics as well as a stabilizer in perfume.ii. It is moderately soluble in water.

iii. ess toxicand non-reacti!e with copperand lead.

DISAD"ANTAGE O# !$PHENOXYETHANOL

i. "ome experts belie!e it to be a toxic ingredient.

ii. #an be an extreme irritant to the eyes and s$in% and can e!en cause blistering.

iii. It also can cause shut down of the central ner!ous system% !omiting and contact

dermatitis.

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http://en.wikipedia.org/wiki/Toxichttp://en.wikipedia.org/wiki/Copperhttp://en.wikipedia.org/wiki/Copperhttp://en.wikipedia.org/wiki/Leadhttp://en.wikipedia.org/wiki/Copperhttp://en.wikipedia.org/wiki/Leadhttp://en.wikipedia.org/wiki/Toxic