plant sterols kit sds.pdf · beta -sitosterol 83-46-5 100 no section 4. first aid measures...

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Revision Date: 7/28/2020 SDS-1123 SAFETY DATA SHEET Plant Sterols Kit Catalog number to reorder this kit: 1123 Recommended storage for these components: -20ºC This kit contains the following products, listed by number and name. 1117-k Steryl Glucosides, 25 mg 1118-k Esterified Steryl Glucosides, 10 mg 1119-k Plant Sterol Mixture, 25 mg/ml, 1 ml chloroform 1110-k beta-Sitosterol, 100 mg 1111-k Desmosterol, 2 mg 1120-k Lanosterol, 100 mg 1121-k Stigmasterol, 25 mg 1122-k Ergosterol, 25 mg 1116-k Coprostanol, 5 mg 1112-k Cholestanol, 100 mg

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Page 1: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 7/28/2020

SDS-1123

SAFETY DATA SHEET

Plant Sterols Kit

Catalog number to reorder this kit: 1123 Recommended storage for these components: -20ºC This kit contains the following products, listed by number and name.

1117-k Steryl Glucosides, 25 mg

1118-k Esterified Steryl Glucosides, 10 mg

1119-k Plant Sterol Mixture, 25 mg/ml, 1 ml chloroform

1110-k beta-Sitosterol, 100 mg

1111-k Desmosterol, 2 mg

1120-k Lanosterol, 100 mg

1121-k Stigmasterol, 25 mg

1122-k Ergosterol, 25 mg

1116-k Coprostanol, 5 mg

1112-k Cholestanol, 100 mg

Page 2: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/7/2020 Version: 9

SDS-1117

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Steryl Glucosides

Product Number(s): 1117; 1117-k

Synonym(s): Sterolins

CAS Number: No data available

Source: Natural, plant Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Steryl Glucosides No data available 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

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SDS-1117 Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20C. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: 283-287C Initial boiling point and boiling range: No data available Flash point: No data available

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SDS-1117 Page 3 of 5

Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform/methanol/DI water, 2:1:0.1 (warm) Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C35H60O6 Molecular weight: 577 (based on beta-sitosteryl glucoside)

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

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SDS-1117 Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Steryl Glucosides No data available

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are not on the Canadian DSL nor NDSL lists. Component CAS Number Steryl Glucosides No data available

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SDS-1117 Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

05/25/2012

10/10/2012

03/11/2014

03/30/2015

11/2/2016

7/28/2017

8/17/2018

4/7/2020

Version 2

Version 3

Version 4: Revised product use statement.

Version 5: Changed company address.

Version 6: Added synonym name.

Version 7: Removed Chemtrec International number.

Version 8: Reviewed, no changes.

Version 9: Updated logo, added Chemtrec international number.

Page 7: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/7/2020 Version: 9

SDS-1118

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Esterified Steryl Glucosides

Product Number(s): 1118; 1118-k

Synonym(s): Esterified sterolins

CAS Number: No data available

Source: Natural, plant Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Esterified Steryl Glucosides No data available 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

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SDS-1118 Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20C. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: No data available Initial boiling point and boiling range: No data available Flash point: No data available

Page 9: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1118 Page 3 of 5

Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform, ethyl ether, pyridine Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C51H90O7

Molecular weight: 815 (based on beta-sitosteryl glucoside palmitate)

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 10: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1118 Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Esterified Steryl Glucosides No data available

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are not on the Canadian DSL nor NDSL lists. Component CAS Number Esterified Steryl Glucosides No data available

Page 11: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1118 Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

05/25/2012

10/10/2012

03/11/2014

03/30/2015

11/3/2016

7/28/2017

8/17/2018

4/7/2020

Version 2

Version 3

Version 4: Revised product use statement.

Version 5: Changed company address.

Version 6: Updated synonym name.

Version 7: Removed Chemtrec International number.

Version 8: Reviewed, no changes.

Version 9: Updated logo, added Chemtrec international number.

Page 12: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/7/2020 Version: 7

SDS-1119

Page 1 of 7

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Plant Sterol Mixture Product Number(s): 1119; 1119-k Source: Natural, plant Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: Cardiovascular system, Central nervous system, Peripheral nervous system,

Kidney, Liver, Blood, Nerves, Heart, Eyes or Skin. GHS Classification: Acute toxicity (oral), Category 4

Skin corrosion/irritation, Category 2 Serious eye damage/eye irritation, Category 2A Carcinogenicity, Category 2 Specific target organ toxicity - repeated exposure, Category 2(Central nervous system, kidney, liver, respiratory) Acute toxicity to the aquatic environment, Category 3

GHS Label Elements: Pictogram(s):

Signal Word: Danger

Health Code Hazard statement(s): H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H351 Suspected of causing cancer. H373 May cause damage to organs through prolonged or repeated exposure. H402 Harmful to aquatic life.

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SDS-1119 Page 2 of 7

Prevention Code Prevention Statement(s): P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapors/spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear eye protection/face protection. P281 Use personal protective equipment as required.

Response Code Response Statement(s): P301, P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel

unwell. P330 Rinse mouth P302, P352 IF ON SKIN: Wash with plenty of soup and water. P332, P313 If skin irritation occurs: Get medical advice/ attention. P305, P351, P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact

lenses, if present and easy to do. Continue rinsing. P337, P313 If eye irritation persists: Get medical advice/attention. P321 Specific treatment (see supplemental first aid instructions). P308, P313 IF exposed or concerned: Get medical advice/attention. P314 Get medical advice/attention if you feel unwell. P362 Take off contaminated clothing and wash before reuse.

Storage Code Storage Statement(s): P405 Store locked up.

Disposal Code Disposal Statement(s): P501 Disposal of contents/container in accordance to

local/regional/national/international regulations.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Chloroform 67-66-3 98.339% Brassicasterol 474-67-9 0.2324% Campesterol 474-62-4 0.4648% Stigmasterol 83-48-7 0.1992% beta-sitosterol 83-46-5 0.7130%

Section 4. First Aid Measures

Inhalation: Move exposed person to fresh air. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately. Consult a physician. Skin: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Thoroughly wash or discard clothing and shoes before reuse. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: If swallowed, do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as collar, tie, belt or waistband. Get medical attention immediately.

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SDS-1119 Page 3 of 7

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Specific hazards arising from the chemical: Slight fire hazard when exposed to high heat; otherwise, practically not flammable. Special protective actions for fire fighters: Evacuate area and fight fire from a safe distance. Do not stay in dangerous zone without suitable chemical protection clothing and self-contained breathing apparatus. Special protective equipment for fire fighters: As in any fire, wear self-contained breathing apparatus pressure-demand, (MSHA/NIOSH approved or equivalent) and full protective gear.

Section 6. Accidental Release Measures

Personal precautions: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Do not breathe vapor or mist. Provide adequate ventilation. Wear appropriate personal protective equipment.

Environmental precautions: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewer. Inform the relevant authorities if the product has caused environmental pollution (sewer, waterways, soil or air).

Methods and Materials for containment and cleaning up: Stop leak if without risk. Prevent entry into sewers, water sources, basements or confines spaces. Contain and collect spillage with inert absorbent material and place in container for disposal according to local regulations. Call for assistance on disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not breathe vapor or mist. Do not ingest. Use only with adequate ventilation. Store in a tightly closed container. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20C. Store in a tightly closed container. Separate from oxidizing materials.

Section 8. Exposure Controls/Personal Protection

Component CAS Number Type Exposure Limits Source Chloroform 67-66-3 TWA (8Hr) 10 ppm USA (ACGIH) TWA 50 ppm USA (OSHA) TWA 2 ppm Australia TWA 2 ppm Belgium MAK 2.5 mg/m3 Germany TWA 10 mg/m3 Hungry MAC-TGG 5 mg/m3 Netherlands VME 50 mg/m3 France MAK 50 mg/m3 Poland TWA 2 ppm UK Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Personal Protective Equipment: Respiratory protection:

Use only in a well ventilated area. Wear an appropriate NIOSH/MSHA approved air-purifying respirator. If

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SDS-1119 Page 4 of 7

warranted, wear a positive pressure air-supplied respirator in situations where there may be potential for airborne exposure. Hand protection: Chemical-resistant, impervious gloves should be worn at all times when handling chemical products. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists or dusts. Recommended: Splash goggles Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Liquid Odor: Characteristic, ethereal odor Odor threshold: 85-87 ppm pH: No data available Melting/Freezing point: -63.5C (-83F) Initial boiling point and boiling range: 62ºC (144ºF) Flash point: No data available Evaporation rate (Butyl acetate = 1): 11.6 Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure (mm Hg): 160 @ 20C (68F) Vapor density (Air = 1): 4.1 Relative density (water = 1): 1.48 Solubility (ies): 0.8g/100g water @ 20C (68F) Partition coefficient (n-octanol/water) as log Pow: 1.97 Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: Under normal conditions of storage and use, hazardous reaction will not occur.

Conditions to avoid: Light, heat, air and incompatibles.

Incompatible materials: Strong caustics; chemically active metals such as aluminum or magnesium powder, sodium and potassium; strong oxidizers.

Hazardous decomposition products: Toxic gases and vapors such as hydrogen chloride, chlorine, phosgene and carbon monoxide may be released in a fire involving chloroform.

Section 11. Toxicological Information

Acute toxicity: Chloroform LC50: Inhalation - Rat – 47,702 mg/m³ @ 4 hours exposure time LD50: Oral - Rat – 908 mg/kg

LD50: Skin- Rabbit- >20 gm/kg

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SDS-1119 Page 5 of 7

Skin corrosion / irritation: Mild irritations. Drying out effect result in rough chapped skin. Danger of skin absorption.

10 mg/24 Hr open

Serious eye damage / irritation: Moderate irritations Eyes-rabbit- 20 mg/24 Hr

Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No data available

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: Category 2 repeated exposure may cause damage to cardiovascular system, central nervous system, peripheral nervous system, blood, liver, kidney, nerves, heart, eyes or skin through prolonged exposure.

Aspiration hazard: No data available

Section 12. Ecological Information

Toxicity:

Fish LC100 Leuciscus idus melantous (Carp) 176 mg/L 48 Hr LC50 Danio rerio (Zebra Danio) 121 mg/L 96 Hr LC50 Ictalurus punctatus (Channel catfish) 126 mg/L 24 Hr

Persistence and degradability: This material is not expected to undergo biodegradation.

Bioaccumulative potential: This material is not expected to significantly bioaccumalate.

Bioaccumulation: Oncorhynchus mykiss (rainbow trout) 8 Hr 30 µCi/L

Oryzias latipes (Medaka, high-eyes) 9 day 107.5 mg/L

Mobility in soil: This material is expected to have a moderate mobility in soil.

Other adverse effects: This material is not expected to be toxic to aquatic life. The LC50/96-Hr value for fish are over 100 mg/L.

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service to dispose of this material.

Section 14. Transportation Information

Transportation quantity: This item shipped as an excepted quantity. DOT (US) UN Number: 1888 UN Proper shipping name: Chloroform solution Transportation hazard class(es): 6.1

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SDS-1119 Page 6 of 7

Packaging group (if applicable): III Reportable Quantity (RQ): 10 lbs. Environmental hazards: No Marine pollutant: No Land Transport ADR/RID UN Number: 1888 UN Proper shipping name: Chloroform solution Transportation hazard class(es): 6.1 Packaging group (if applicable): III Environmental hazards: No Marine pollutant: No Maritime Transport IMDG UN Number: 1888 UN Proper shipping name: Chloroform solution Transportation hazard class(es): 6.1 Packaging group (if applicable): III Environmental hazards: No Marine pollutant: No Air Transport ICAO/IATA UN Number: 1888 UN Proper shipping name: Chloroform solution Transportation hazard class(es): 6.1 Packaging group (if applicable): III Environmental hazards: No Marine pollutant: No

Section 15. Regulatory Information

DSL/NDSL status: This product contains the following components that are on the Canadian DSL. Component CAS Number Chloroform 67-66-3

TSCA: This product contains the following components that are on the TSCA inventory. Component CAS Number Chloroform 67-66-3

SARA 302 Components: Component CAS Number Chloroform 67-66-3

SARA 313 Components: The following components are subject to reporting levels established by SARA Title III, Section 313. Component CAS Number Chloroform 67-66-3

SARA 311/312 Hazards: Acute health hazard, chronic health hazard

California Hazardous Substance List: Component CAS Number Chloroform 67-66-3

Delaware Air Quality Management List: Component CAS Number Chloroform 67-66-3

Massachusetts Right To Know Components: Component CAS Number Chloroform 67-66-3

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SDS-1119 Page 7 of 7

Minnesota Right To Know Components: Component CAS Number Chloroform 67-66-3

New Jersey Right To Know Components: Component CAS Number Chloroform 67-66-3

New York Right To Know Components: Component CAS Number Chloroform 67-66-3

Pennsylvania Right To Know Components: Component CAS Number Chloroform 67-66-3

California Prop. 65 Components: This product contains a chemical known to the state of California to cause cancer. Component CAS Number Chloroform 67-66-3

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary: 10/23/2012

03/11/2014

03/30/2015

7/28/2017

8/17/2018

12/11/2018

4/7/2020

Version 1

Version 2: Revised product use statement.

Version 3: Changed company address.

Version 4: Removed Chemtrec International number.

Version 5: Reviewed, no changes.

Version 6: Percentages changed.

Version 7: Updated logo, added Chemtrec international number. Reference: Centers for Disease Control and Prevention. "Chloroform RTECS." National Institute for Occupational Safety and Health. 2011. July 12, 2011. <http://www.cdc.gov/niosh-rtecs/MN8D8678.html>. Kegley, S.E., Hill, B.R., Orme S., Choi A.H., “PAN Pesticide Database.” Pesticide Action Network, North America (San Francisco, CA, 2010), http:www.pesticideinfo.org.

Page 19: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/6/2020 Version: 6

SDS-1110-k

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: beta-Sitosterol

Product Number(s): 1110-k

Synonym(s): 5-Cholesten-24-beta-ethyl-3-beta-ol

CAS Number: 83-46-5

Source: Synthetic or natural plant Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous beta-Sitosterol 83-46-5 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

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SDS-1110-k Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20ºC. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: 139-142°C Initial boiling point and boiling range: No data available Flash point: No data available

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SDS-1110-k Page 3 of 5

Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C29H50O

Molecular weight: 415

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 22: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1110-k Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number beta-Sitosterol 83-46-5

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are on the Canadian NDSL list. Component CAS Number beta-Sitosterol 83-46-5

Page 23: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1110-k Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

10/26/2012

04/21/2014

03/30/2015

7/28/2017

8/17/2018

4/6/2020

Version 1: New

Version 2: Revised product use statement.

Version 3: Changed company address.

Version 4: Removed Chemtrec International number.

Version 5: Reviewed, no changes.

Version 6: Updated logo, added Chemtrec international number.

Page 24: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/6/2020 Version: 6

SDS-1111-k

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Desmosterol

Product Number(s): 1111-k

Synonym(s): 5,24-Cholestadien-3-beta-ol

CAS Number: 313-04-2

Source: No data available Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Desmosterol 313-04-2 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

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SDS-1111-k Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20ºC. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: No data available Initial boiling point and boiling range: No data available

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SDS-1111-k Page 3 of 5

Flash point: No data available Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C27H44O

Molecular weight: 385

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 27: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1111-k Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Desmosterol 313-04-2

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are not on the Canadian DSL nor NDSL lists. Component CAS Number Desmosterol 313-04-2

Page 28: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1111-k Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

10/26/2012

04/30/2014

03/30/2015

7/28/2017

8/17/2018

4/6/2020

Version 1: New

Version 2: Revised product use statement.

Version 3: Changed company address.

Version 4: Removed Chemtrec International number.

Version 5: Reviewed, no changes.

Version 6: Updated logo, added Chemtrec international number.

Page 29: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/7/2020 Version: 8

SDS-1120

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Lanosterol

Product Number(s): 1120; 1120-k

Synonym(s): No data available

CAS Number: 79-63-0

Source: Synthetic or plant Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Lanosterol 79-63-0 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

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SDS-1120 Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20C. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: No data available Initial boiling point and boiling range: No data available Flash point: No data available

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SDS-1120 Page 3 of 5

Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C30H50O

Molecular weight: 427

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 32: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1120 Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Lanosterol 79-63-0

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are on the Canadian DSL list. Component CAS Number Lanosterol 79-63-0

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SDS-1120 Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

05/25/2012

10/10/2012

03/13/2014

03/30/2015

7/28/2017

8/17/2018

4/7/2020

Version 2

Version 3

Version 4: Revised product use statement.

Version 5: Changed company address.

Version 6: Removed Chemtrec International number.

Version 7: Reviewed, no changes.

Version 8: Updated logo, added Chemtrec international number.

Page 34: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/7/2020 Version: 8

SDS-1121

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Stigmasterol

Product Number(s): 1121; 1121-k

Synonym(s): 5,22-Cholestadien-24-beta-ethyl-3-beta-ol

CAS Number: 83-48-7

Source: Synthetic Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Stigmasterol 83-48-7 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

Page 35: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1121 Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20C. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: 165-167C Initial boiling point and boiling range: No data available Flash point: No data available

Page 36: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1121 Page 3 of 5

Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C29H48O Molecular weight: 413

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 37: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1121 Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Stigmasterol 83-48-7

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are not on the Canadian DSL nor NDSL lists. Component CAS Number Stigmasterol 83-48-7

Page 38: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1121 Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

05/252012

10/10/2012

03/13/2014

03/30/2015

7/28/2017

8/17/2018

4/7/2020

Version 2

Version 3

Version 4: Revised product use statement.

Version 5: Changed company address.

Version 6: Removed Chemtrec International number.

Version 7: Reviewed, no changes.

Version 8: Updated logo, added Chemtrec international number.

Page 39: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/7/2020 Version: 6

SDS-1122

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Ergosterol

Product Number(s): 1122; 1122-k

Synonym(s): No data available

CAS Number: 57-87-4

Source: Synthetic or plant Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Ergosterol 57-87-4 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

Page 40: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1122 Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20ºC. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: 156-158°C Initial boiling point and boiling range: No data available Flash point: No data available

Page 41: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1122 Page 3 of 5

Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C28H44O

Molecular weight: 397

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 42: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1122 Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Ergosterol 57-87-4

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects.

Page 43: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1122 Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary: 10/12/2012

03/13/2014

03/30/2015

7/28/2017

8/17/2018

4/7/2020

Version 1: New

Version 2: Revised product use statement.

Version 3: Changed company address.

Version 4: Removed Chemtrec International number.

Version 5: Reviewed, no changes.

Version 6: Updated logo, added Chemtrec international number.

Page 44: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/6/2020 Version: 8

SDS-1116

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Coprostanol

Product Number(s): 1116; 1116-k

Synonym(s): 5-beta-Cholestan-3-beta-ol

CAS Number: 360-68-9

Source: Semisynthetic Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Coprostanol 360-68-9 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

Page 45: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1116 Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20C. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: 101-103C Initial boiling point and boiling range: No data available

Page 46: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1116 Page 3 of 5

Flash point: No data available Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform, ethyl ether, warm methanol Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C27H48O

Molecular weight: 389

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 47: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1116 Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Coprostanol 360-68-9

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are not on the Canadian DSL nor NDSL lists. Component CAS Number Coprostanol 360-68-9

Page 48: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1116 Page 5 of 5

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

05/25/2012

10/10/2012

03/11/2014

03/30/2015

7/28/2017

8/17/2018

4/6/2020

Version 2

Version 3

Version 4: Revised product use statement.

Version 5: Changed company address.

Version 6: Removed Chemtrec International number.

Version 7: Reviewed, no changes.

Version 8: Updated logo, added Chemtrec international number.

Page 49: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

Revision Date: 4/6/2020 Version: 6

SDS-1112-k

Page 1 of 5

SAFETY DATA SHEET

Section 1. Product and Company Identification

Product Name: Cholestanol

Product Number(s): 1112-k

Synonym(s): 5-alpha-Cholestan-3-beta-ol

CAS Number: 80-97-7

Source: No data available Product Use: This product is to be used for research only. It is not intended for drug or

diagnostic use, human consumption or to be used in food or food additives.

Matreya LLC 2178 High Tech Road, State College, PA 16803 Tel: 800-342-3595/814-355-1030 Fax: 814-355-1031 Email: [email protected] Web: www.matreya.com 24 Hour Emergency Number: Chemtrec 800-424-9300 (within United States) 703-527-3887 (International)

Section 2. Hazards Identification

Emergency Overview: Target Organs: No data available GHS Classification: Not a hazardous substance according to GHS classification standards.

Section 3. Composition/Information on Ingredients

Product Name CAS Number Percent Hazardous Cholestanol 80-97-7 100 NO

Section 4. First Aid Measures

Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Skin: Wash with soap and water. Get medical attention if irritation develops or persists. Eyes: Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel. Ingestion: Wash out mouth with water, keep at rest. Seek immediate medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.

Page 50: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1112-k Page 2 of 5

Section 5. Fire Fighting Measures

Suitable extinguishing media: Use dry chemical, alcohol-resistant appropriate foam, carbon dioxide, or water spray. Specific hazards arising from the chemical: No data available Special protective actions for fire fighters: No data available Special protective equipment for fire fighters: Wear breathing apparatus and use water spray to keep fire-exposed containers cool.

Section 6. Accidental Release Measures

Personal precautions: Wear appropriate personal protective equipment. After contact with skin, wash immediately with plenty of water.

Environmental precautions: Do not let product enter drains.

Methods and Materials for containment and cleaning up: Sweep up and keep in suitable, closed container for disposal.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with eyes, skin or clothing. Do not ingest. Use only with adequate ventilation. Keep sealed when not in use. Wear appropriate personal protective equipment.

Conditions for safe storage, including incompatibilities: Recommended storage temperature: -20ºC. Keep container tightly closed in a dry and well-ventilated place.

Section 8. Exposure Controls/Personal Protection

This product contains no substances with occupational exposure limit values.

Engineering Controls: No specific ventilation required. Personal Protective Equipment: Respiratory protection:

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection: For prolonged or repeated contact use protective gloves. Recommended: Nitrile rubber Eye protection: Safety eyewear should be worn at all times to avoid exposure to liquid splashes, mists, or dusts. Recommended: Safety glasses with side shields or goggles. Skin protection: Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. Recommended: Lab coat

Section 9. Physical and Chemical Properties

Appearance: Solid Odor: No data available Odor threshold: No data available pH: No data available Melting/Freezing point: 143-144°C Initial boiling point and boiling range: No data available Flash point: No data available

Page 51: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1112-k Page 3 of 5

Evaporation rate: No data available Flammability (solid, gas): No data available Upper/Lower flammability or explosive limit: No data available Vapor pressure: No data available Vapor density: No data available Relative density: No data available Solubility (ies): Chloroform Partition coefficient (n-octanol/water): No data available Auto-ignition temperature: No data available Decomposition temperature: No data available Viscosity: No data available Molecular formula: C27H48O

Molecular weight: 389

Section 10. Stability and Reactivity

Reactivity: Stable under recommended storage conditions.

Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reaction: No data available

Conditions to avoid: No data available

Incompatible materials: No data available

Hazardous decomposition products: No data available

Section 11. Toxicological Information

Acute toxicity: No data available

Skin corrosion / irritation: No data available

Serious eye damage / irritation: No data available Respiratory or skin sensitization: No data available

Germ cell mutagenicity: No data available

Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by IARC, ACGIH, NTP or OSHA.

Reproductive toxicity: No data available

Specific target organ toxicity - single exposure: No data available

Specific target organ toxicity - repeated exposure: No data available

Aspiration hazard: No data available

Page 52: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1112-k Page 4 of 5

Section 12. Ecological Information

Toxicity: No ecological data available for this product. Persistence and degradability: No data available

Bioaccumulative potential: No data available

Bioaccumulation: No data available

Mobility in soil: No data available

Other adverse effects: No data available

Section 13. Disposal Consideration

Disposal methods: Observe all federal, state and local environmental regulations.

Section 14. Transportation Information

DOT (US) UN Number: Not dangerous goods Land Transport ADR/RID UN Number: Not dangerous goods Maritime Transport IMDG UN Number: Not dangerous goods Air Transport ICAO/IATA UN Number: Not dangerous goods

Section 15. Regulatory Information

Product Name CAS Number Cholestanol 80-97-7

SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: No 311/312 SARA Hazards

California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects. DSL/NDSL status:

This product contains the following components that are on the Canadian DSL list. Component CAS Number Cholestanol 80-97-7

Page 53: Plant Sterols Kit SDS.pdf · beta -Sitosterol 83-46-5 100 NO Section 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician

SDS-1112-k Page 5 of 5

TSCA

This product contains the following components that are listed on the TSCA inventory.

Component CAS Number Cholestanol 80-97-7

Section 16. Other Information

Manufacturer Supplementary Notes: The statements contained herein are based upon technical data that MATREYA LLC believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. MATREYA LLC MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. MATREYA LLC ASSUMES NO LIABILITY FOR ANY USE OF THESE CHEMICALS BY THE END USER.

Revision Summary:

10/26/2012

04/30/2014

03/30/2015

7/28/2017

8/17/2018

4/6/2020

Version 1: New

Version 2: Revised product use statement.

Version 3: Changed company address.

Version 4: Removed Chemtrec International number.

Version 5: Reviewed, no changes.

Version 6: Updated logo, added Chemtrec international number.