Impaired mucocilary reaction

Age (7 y/o) Poor Diet Asthmatic Patient

IgE StimulationAtmospheric Pollutants

Asthma attacks

Mast cell Degranulation

Streptococcus Pneunoniae

Gain access to the center of the respiratory tract through Inspiration or aspiration

Activation of defense mechanism

Lose effectiveness of defense mechanism

Penetrate the LRT (lungs)

Multiply

Colonization begins Irritation of airway

Release of damaging toxin Increase goblet cell

Occluded airway Inflammation airway Increase mucus production

Chapter 6

PATHOPHYSIOLOGY

Predisposing Factor Precipitating Factor Risk Factor

Exudates from Bacteria Erodes the lungs

Dehydration

Decrease Fluid intake Excessive sweating

Fluid Volume deficit

Loss of fluid and electrolyte

Impaired thirst sensation

Hypomagnesemia

Malabsorption process disorder

Impaired absorption of

Hypophosphatemia

Lung consolidation

Hypoxia

Muscle fatigue & exhaustion

Body malaise

Decrease CO2

Vasodilation Mucus become increasingly viscousOccluded Airway

CracklesCough

Increase respiratoryAirway constriction

DOB

Increase blood flow

Impaired O2 and CO2 exchange Increase airway resistance

Plasma and carbohydrates rich fluid leakage

Accumulation of edematous fluid

Inflamed & fluid filled alveolar sacs

Respiratory muscle works harder

Dead space happened