post thoracotomy pain
DESCRIPTION
a presentation about post thoracotomy in acute and chronic forms and managementsTRANSCRIPT
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Postthoracotomy Pain
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Relevant Clinical Anatomy
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Pain impulses from the skin, ribs, and parietal pleura are transmitted through the intercostal nervesfrom the visceral pleura through autonomic nerves from the lung through the vagus nervefrom the mediastinum, pericardial pleura, and diaphragm through the pherenic nerves
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Clinical Presentation
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
During the Acute postoperative phase, patients experiencesharp pain that increases with breathing and coughing. The pain is also associated with numbness, especially along the scarsite
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Chronic pain after thoracotomy is typically a combination of neuropathic and nociceptive pain
Burning pain and allodynia Aching chest or back painMyofascial pain (referred shoulder pain may occur, especially after procedures that cause injury to the diaphragm or the phrenic nerve)
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Differential Diagnosis
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Herniated discNeuroforaminal stenosisRib pathologyPostherpetic neuralgia Slipping rib syndromeCostochondritisTietze's syndromeMyofascial pain syndrome
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Acute Pain Management for Patients UndergoingThoracotomy
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Management of thoracotomy pain can be difficult, but thebenefits of effective pain control are significantSystemic opiatesRegional analgesicsNew oral and parenteral agents
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Pain is a key component in the alteration of lung function after thoracic surgery
Postoperative analgesia to reduce pulmonary complications andattenuate the stress response
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Almost 200,000 patients a year are diagnosed with bronchogeniccarcinoma, and nearly one-quarter of these patients will undergo surgical resection
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Ineffective chest expansion due to pain may predispose toAtelectasisVentilation/ perfusion mismatchingHypoxemiaInfection
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Thus, the goal of the clinician is to develop an analgesicregimen that provides effective pain relief to allow postoperativethoracotomy patients the ability to maintaintheir functional residual capacity by deep breathing
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Effective clearing of secretions with cough and early mobilization can lead to quicker recovery and shorter length of hospital stay
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Inadequate acute postoperative pain management may contribute tothe development of a chronic postthoracotomy pain syndrome(52%)
Acute pain after thoracic surgery predicts long-term post-thoracotomy pain. Clin J Pain 1996;12:50–5
Pathogenesis and management of persistent postthoracotomy pain. Chest Surg Clin N Am 1998;8:703–22
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
The pain associated with thoracotomy incisions can bedifficult to target and quantify, and prior studies have evaluated :
Chest tube painIncisional painVisceral painCoughing or movement
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Systemic administration of opioids is the simplest and most common method to provide analgesia for postoperative pain
Unfortunately systemic opioid administration may not be adequatefor treating the intense postoperative pain associated with thoracotomy
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Ketorolac, tramadol, COX-2 inhibitors, and ketamine are other potentially useful analgesic agents as alternatives or adjuncts to opioids
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
To improve the quality of analgesia, two classes of drugs canbe administered concurrently to obtain a synergistic analgesic effect while minimizing the side effects of each drug
Surgical technique itself can be modified in an attempt to reduce the impact of postoperative pain
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Concepts in Postoperative Pain
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Pain can be defined as an unpleasant sensory and emotionalexperience associated with actual or potential tissue damage
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Local tissue damage results in inflammation and propagationof stimuli to the central nervous system
These stimuli are modulated by Excitatory [NMDA]) Inhibitory (opiate) pathways
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Animal data have shown that administration of low doses of systemic morphine before noxious stimulation suppresses spinal cord hyperexcitability, whereas administration of doses after noxiousstimulation does not completely blunt it
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Because the NMDA receptor has been implicated in the generationand maintenance of spinal cord “wind-up,” NMDA antagonists(eg, ketamine and dextromethorphan) are logical candidates for preemptive analgesia
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Chronic Postthoracotomy Pain
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Up to 50% of patients undergoing thoracotomy will develop chronic pain related to the surgical site
Chronic postthoracotomy pain has been defined as a continuousdysesthetic burning and aching in the general area of the incision that persists at least 2 months after thoracotomy
Surgical aspects of chronic postthoracotomy pain. Eur J Cardiothorac Surg 2000;18:711–6
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Although no one surgical technique has been proven to decrease the incidence of chronic pain, intercostal nerve damage due to rib retraction seems to be involved in the development of the neuralgia
Preliminary findings in the neurophysicological assessment of intercostal nerve injury during thoracotomy.
Eur J Cardiothorac Surg 2002;21:298–301
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Initiation of epidural bupivacaine/ morphine before surgical incision reduced the incidence of long-term pain[The effects of three different analgesia techniques on long-term postthoracotomy pain. Anesth Analg 2002;94:11–5]
Patients with increased postoperative pain had an increased incidence of chronic postoperative pain [Acute pain after thoracic surgery predicts long-term post-thoracotomy pain. Clin J Pain 1996;12:50–5]
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Epidural Analgesia as the Mainstay of Postoperative Pain Management
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Epidural analgesia has emerged as the analgesic technique of choice for postoperative thoracotomy pain management
Provide excellent pain control Avoids much of the sedation associated with systemic opiates Epidural Catheter allows for continued dosing postoperatively Avoids much of the motor blockade associated with intrathecal drug
administration
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Much lower doses of drug administered in the epidural space are needed ( in compare with systemic administration )
Postoperative patients can consume on the order of 50 to100 mg of intravenous morphine during the first 24 hourspostoperatively when administered by a PCA device In comparison, epidural doses of 5 mg of morphine canprovide postoperative analgesia for 12 to 24 hours
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Commonly used opioid–local anesthetic mixtures :Fentanyl-bupivacaineMorphine-bupivacaineFentanyl-ropivacaine
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Epidural fentanyl 5 μg/mL combined with bupivacaine 0.1% providedan optimal balance between pain relief and side effects
WALDMAN 2011
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
TEA was effective in control of the incision pain but not effective inalleviation of postthoracotomy shoulder pain, which is mostlikely related to irritation of the pericardium or the pleura.
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Patients receiving thoracic epidural analgesia for postthoracotomy pain, phrenic nerve infiltration with 10 mL of ropivacaine just before lung expansion and chest closure reduced the incidence and delayed the onset of ipsilateral shoulder pain by about 50% during the first 24 hours after open lung resection
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Hypotension and urinary retention are common side effects related to TEA
Paravertebral block was found to be as effective as epidural block with local anestheticHowever, paravertebral block had a better side effect profile.
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
In many clinical settings, epidural analgesia is used as often as possible, whereas systemic analgesia is reserved for situations in which epidural analgesia is unsuccessful or contraindicated : CoagulopathyInfectionNeurologic disease
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
A meta-analysis of pre-emptive use of thoracic epidural analgesia concluded that it offered improved postoperative analgesia in the first 48 hours after surgery, but had no impact on chronic post-thoracotomy pain
Other techniques such as intrapleural analgesia, paravertebral block, cryoanalgesia, and infiltration at the incision site did not effect the incidence of post-thoracotomy pain syndrome
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Postoperative epidural pain control may significantlydecrease pulmonary morbidity
The comparative effects of postoperative analgesic therapies on pulmonary outcome: cumulative meta-analyses of randomized, clinical trials. Anesth Analg 1998;86:598–612
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Thoracic Versus Lumbar Catheters
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Both lumbar and thoracic epidural catheters can be used for postoperative thoracotomy pain management
In majority of studies, no significant differences in analgesia andpulmonary function were seen; however, less opioid wasrequired in patients receiving thoracic epidural analgesia
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
In one study, thoracic epidural analgesia was associated with an increased incidence of ventilatory depression
Adverse effects of extradural and intrathecal opiates: report of a nationwide survey in Sweden. Br J Anaesth 1982;54:479–86
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
With thoracic epidural placement, the risk of injuring spinal cord tissue if the dura is inadvertently punctured is theoretically greater, and placement of a thoracic epidural catheter can be technically moredifficult due to the greater caudad angulation of the spinous processes
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Patients who received epidural bupivacaine had a reduced incidence of supraventricular tachyarrhythmias when compared with patients whoonly received epidural opiates
Thoracic epidural bupivacaine attenuates supraventricular tachyarrhythmias after pulmonary resection.
Anesth Analg 2001;93:253–9
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Thoracic epidural anesthesia (TEA) is the gold standard modality for pain control
WALDMAN 2011
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Intercostal Nerve Block
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Blockade of intercostal nerves interrupts C-fiber afferenttransmission of impulses to the spinal cord
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
A single intercostal injection of a long-acting local anesthetic can provide pain relief and improve pulmonary function for up to 6 hours
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
To achieve longer durations of analgesia, a continuous extrapleural intercostal nerve block technique has been developed in which a catheter is placed percutaneously into an extrapleural pocket by the thoracic surgeon
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
A continuous intercostal catheter allows frequent dosing or infusions of local anesthetic agents and avoids multiple needle injections
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Shorter-acting local anesthetic, lidocaine, was just as effective as thelonger-acting agent bupivacaine
Cardiotoxicity of bupivacaine is far more dangerous than with lidocaine, especially in light of the fact that systemic absorption is great with an intercostal block
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
However, the advent of newer long-acting local anesthetic agents,including ropivacaine and levo-bupivacaine, has introduced new possibilities for prolonged analgesia with minimal cardiotoxicity
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Extrapleural intercostal analgesiaor
Epidural analgesia?
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
In one study:Patients in the intercostal group required more supplemental morphineComparative study of continuous extrapleural intercostal nerve block and lumbar epidural morphine in post-thoracotomy pain. Can J Surg 1997;40:431–6”
In another study: With similar analgesia Vomiting, pruritus, and urinary retention occurring only in the epidural groupContinuous intercostal nerve block versus epidural morphine for postthoracotomy analgesia. Ann Thorac Surg 1993;55:377–80.
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
In one study:Both thoracic epidural analgesia and extrapleural intercostalanalgesia were safe and effective
Intercostal analgesia should be instituted in patients who do not qualify for thoracic epidural analgesia
Prospective, randomized comparison of extrapleural versus epidural analgesia for postthoracotomy pain. Ann Thorac Surg 1998;66:367–72
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Intrapleural Analgesia
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Local anesthetic agents can also be administered through a catheter positioned inside the pleural cavity as another modality to anesthetize intercostal nerves
The mechanism of action appears to be diffusion across the parietalpleura
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
There are inconsistent results in Interpleural analgesia studies:
Loss of local anesthetic through the chest tube Dilution of local anesthetic with blood and exudative fluid present in the pleural
cavity Binding of local anesthetic with proteins Altered diffusion across the parietal pleural following surgical manipulation and
inflammation
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Nonsteroidal Anti-Inflammatory Drugs
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Ketorolac is an NSAID available in a parenteral form, and it has been shown to be an effective adjunct agent to improve the quality of intercostal and epidural analgesia
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Nonsteroidal anti-inflammatory drugs, however, have been associated with inhibition of platelet aggregation, gastrointestinal bleeding,and renal toxicity, limiting their usefulness in clinical practice
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Blocking COX-1 activity alters platelet function and promotes gastrointestinal bleeding, whereas blocking COX-2 inhibits production of prostaglandins that mediate inflammation and pain-signalingtransmission
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Oral celecoxib (Celebrex) and rofecoxib (Vioxx), and the parenteral parecoxib have been developed to relieve pain and lessen the risk of gastrointestinal bleeding
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Tramadol
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
It binds to opiate receptors and inhibits epinephrine and serotonin reuptake, but lacks many of the side effects associated with other drugs with similar sites of action
Findings do provide an alternative to opiates
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Ketamine
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Ketamine confers analgesia by blocking the NMDA receptor
Side effects, however, including catecholamine release and significant cognitive impairment, limit the utility of this agent
Several authors suggest that ketamine may be a useful adjunct
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Paravertebral Nerve Block
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Paravertebral analgesia can be an effective alternative to epiduralanalgesia in thoracotomy patients
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
In one study in comparison analgesia through a thoracic epidural catheter,patients in the thoracic paravertebral group had lowerpain scores, less postoperative morphine consumption,and better preservation of pulmonary function
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
In addition,Side effects such as nausea, vomiting, urinary retention and hypotension were more problematic in the epidural group
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Video-Assisted Thoracic Surgery
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
When compared with standard thoracotomy incisions, patients undergoing VATS had less postoperative pain and narcotic consumption in multiple studies
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Phrenic Nerve Infiltration
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Patients undergoing thoracic surgery frequently complainof ipsilateral shoulder pain due to diaphragmatic irritation
Infiltration of 10 mL of 1% lidocaine into the periphrenic fat pad atconclusion of surgery at the level of the diaphragm in patients undergoing thoracotomy significantly decreased incidence of ipsilateral shoulder pain and an overall reduction in pain score when compared with placebo infiltration
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Cryoablation
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Much of the pain associated with thoracotomy is mediatedthrough the intercostal nerves
Patients undergoing minithoracotomy for minimally invasive cardiac surgery benefited from cryoablation of the intercostal nerve at the completion of surgery
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Chronic Post-thoracotomy Pain
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
The first reference to chronic post-thoracotomy pain was in 1944 by United States Army surgeons who noted ‘chronic intercostal pain’ in men who had thoracotomy for chest trauma during the Second World War
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Chronic post-thoracotomy pain is defined by the International Association for the Study of Pain as pain that recurs or persists along a thoracotomy incision at least 2 months following the surgical procedure
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
It is typically burning and dysesthetic in nature and has many features of neuropathic pain
Post-thoracotomy pain also may result, at least in part, from a non-neuropathic origin (myofascial pain)
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Incidence of post-thoracotomy pain as ranging from 25–60 % which makes postthoracotomy pain the commonest complication of thoracotomy
The majority of patients experience only mild pain, but 3–16 % experience moderate to severe pain
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
The risk of chronic pain following certain types of surgical procedures is increased in women and decreased in the elderly
Persistent postsurgical pain: risk factors and prevention.Lancet , 2006 367: 1618–1625
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Two studies explored the role of preoperative anxiety/depression in relation to development of post-thoracotomy pain, both showing no relationship
A study exploring the role of intercostal nerve damage in chronic pain after thoracic surgery. Eur J Cardiothorac Surg 2006 29: 873–879
Acute pain after thoracic surgery predicts long-term post-thoracotomy pain. 1997, Clin J Pain 12: 50–55
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Thoracotomy, along with limb amputation, is considered to be the procedure that elicits the highest risk of severe chronic postoperative pain
Pain has been reported more profoundly around the surgical site or scar
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Others factorsNeuroma formationHealing rib fracture Frozen shoulderLocal infection/pleurisyCostochondritis/costochondral dislocationLocal tumor recurrencePsychological overlay
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Injury of intercostal muscles, the serratus anterior, the latissimus dorsi, and the shoulder girdle muscles may cause significant myofascial painthat may even results in frozen shoulder
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Pleurectomy is a strong risk factorSternal osteomyelitis Sternal fractureIncomplete healingSternocostal chondritisBrachial plexus injuryEntrapment of nerves from sternal wires
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Even hypersensitivity reaction against the metal wires werefound to be other possible factors for development of PTPSafter thymectomy and coronary artery bypass surgery
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Pathology
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Tissue injury results in the release of local inflammatory mediators Peripheral sensitization
These actions activate intracellular signalling pathways on nociceptive terminal membranes reducing threshold and increasing excitability
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
This hypersensitivity reduces the intensity of theperipheral stimulus needed to activate nociceptors at the site of inflammation (primary hyperalgesia)
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
The hyperexcitable state of the spinal cord dorsal horn that follows release of humoral signals from noxious peripheral stimuli is referred to as central sensitization
Prolonged central sensitization can lead to long-lasting alterations in the central nervous system (CNS) and can contribute to chronic pain long after withdrawal of the acute painful stimulus
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Thoracotomy is associated with surgical trauma to the intercostal nerves
Injured primary sensory neurons begin to fire action potentials spontaneously as a result of increased or novel expression and altered trafficking of sodium channels
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
This altered activity contributes to spontaneous pain, heightens pain sensitivity, and produces tactile allodynia
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
When a nerve is damaged, it heals by fibrosis and neuroma formation, which can lead to abnormal signal transduction and transmission to the CNS, generating both neuronal and glial responses, including the elevation of spinal prostaglandin (PGE2) concentrations
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Although pre-emptive effects of gabapentinoids in reduction of postoperative morphine usage and opioid related adverse effects such as nausea, vomiting, and urinary retention have been established, their role in the prevention of long term pain has not been fully explored
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Strategies for Treating Long Term Pain
Preventing and treating pain after thoracic surgery. Anesthesiology 104: 594–600
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Study between radiofrequency of the dorsalroot ganglia, pulsed radiofrequency ablation of intercostalsnerves, and pharmacotherapy:Radiofrequency ablation (RFA) of the DRG is superiorto pulsed radiofrequency ablation of intercostal nerves andto pharmacotherapy
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Because of the risk of RFA on the dorsal root ganglia, they recommended that such procedure be reserved for patients with intractable pain with failure of other conservative pain management approaches
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Initial Hx & PE
At risk for recurrence or Anatomic Abnormality
NO
Physical therapy/Relaxation/
Psychological evaluation
CXR & CT SCAN
YES
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Hypertrophic scarTrigger point,neuroma
NO
NSAIDS (SYSTEMIC OR TOPICAL)/ Tramadol /Topical caspaicine
Local anesthetic /+ steroid
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Symptoms consistent With neuropathic pain
NO
Persistent pain YES
Consider TENS
YESTactile allodynia Topical lidocaine patch
NO
TCA or Anticonvulsants /considerNMDA Antagonists or calcitonin
Continue therapy, weaning as indicated
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Candidate for opioid trial or nerve blocks? yes
Trial ofopioidtherapy
NOAcupuncture / Alternative therapies
Sympathetic component?YES
Sympathetic Block
Intercostal cryo / pulse RF
Intercostal Nerve BlockParavertebral Nerve blockThoracic Epidural Steroid Injection
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist
Persistent pain? YES
Neuromodulation
NO
Dr Mehran Rezvani pain fellowship anesthesiologist & acupuncturist