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2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group 1 Nuclear Medicine Artifacts SCPMG Medical Imaging Technology & Informatics Medical Physics Group Brian Helbig, MS, DABR Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group 2 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Symmetric energy windows 3

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Page 1: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

1

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

1

Nuclear Medicine Artifacts

SCPMG Medical Imaging Technology & Informatics

Medical Physics Group

Brian Helbig, MS, DABR

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group2

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Symmetric energy windows

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Page 2: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

2

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Dynamic clinical study – Energy peak shift – Electrical grounding problem

4

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Asymmetric window

5

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Symmetric/Asymmetric energy windows - Poor PMT balance and crystal hydration

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Page 3: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

3

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Asymmetric energy window – fault in energy correction map

7

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Asymmetric energy window – clinical example with I-123 and Tc-99m

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Clinical example - Tl-201 uniformity - Defective linearity correction

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Page 4: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

4

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Uniformity – Ga-67 – Separate and sum of energy windows

10

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Image without linearity or energy corrections

11

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Side-by-side comparison with and without uniformity corrections

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Page 5: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

5

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Fault energy correction map – Clinical study

13

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Loss of hermetic seal/optical coupling

14

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Cracked crystal – Puncture/impact

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Page 6: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group16

Cracked crystal – Puncture/impact

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Cracked crystal - Thermal

17

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Crystal hydration

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Page 7: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

7

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Crystal Irregularities

19

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Uniformity – Defective PM Tube

20

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Uniformity – Defective PM tube (newer digital camera)

21

Page 8: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

8

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Defective PMT at FoV edge

22

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Clinical bone scan – defective PM tube

23

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Maladjusted PM tube

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Page 9: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

9

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Unacceptable extrinsic floods – Low energy collimator misalignment

25

http://www.nuclearfields.com/images/photo-microlinear2.gif

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Unacceptable extrinsic floods – Low energy collimator angulation

26

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Unacceptable extrinsic flood – Collimator septa damage - Puncture

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Page 10: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

10

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Clinical example – Collimator star pattern

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Fillable flood source - Air bubble

29

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Fillable flood source - Non-uniform mixing

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Page 11: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

11

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Fillable flood source – bulging sides

31

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Fillable flood source – Adherence of activity to the container at the filling site (algae)

32

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Non-Uniformity in Cobalt Sheet Source

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Page 12: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

12

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Point Source Geometry and multihead systems

34

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

NEMA slit pattern – Unacceptable difference in x and y spatial resolution

35

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Intrinsic spatial resolution - Faulty linearity correction

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Page 13: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

13

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Extrinsic Spatial Resolution - Moiré pattern

37

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Uniformity and High Count Rates

38

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Poor spatial resolution at high count rates due to misplaced events

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Page 14: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

SPECT Uniformity – simulation with no noise – Effect of projection sampling

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Comparison of high and low count densities

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Single head SPECT uniformity – Ring artifact from real data

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Page 15: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

15

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Dual head SPECT – Clinical partial ring artifact

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

SPECT non-uniformity from high temperature

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

SPECT non-uniformity from outdated uniformity corrections

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Page 16: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

16

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Myocardial Perfusion SPECT – With and without uniformity defect

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Center of Rotation (COR) Offset

47

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Clinical SPECT brain perfusion – Effect of COR offset

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Page 17: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

17

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Effect of detector head tilt - Myocardial perfusion study

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Effects of color table – Myocardial perfusion

50

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Whole body Scan – Faulty PM tube old linearity and energy corrections

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Page 18: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Whole body scan – Co57 versus Tc-99m energy window

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Whole Body Scan – Contamination on handkerchief

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Gated SPECT acquisition – Problems due to heart arrhythmia

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Page 19: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

System uniformity – Contaminated collimator

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Positron range and image quality

56

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

PET detector failure

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Page 20: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Controller board failure

58

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Faulty timing calibration

59

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Memory board failure

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Page 21: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group61

Normalization

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Faulty normalization

62

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Scatter correction artifact

63

Page 22: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

22

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Scatter correction artifact

64

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Intravenous contrast artifact

65

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Intravenous contrast artifacts

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Page 23: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Breathing motion artifact

67

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Subcutaneous tracer infiltration

68

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Contamination at injection site

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Page 24: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

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Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Contamination during flushing

70

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Contamination post injection

71

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Data entry errors and SUV analysis

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Page 25: PowerPoint Presentation...2/14/2019 1 Medical Imaging Technology & Informatics (MITI) Southern California Permanente Medical Group Medical Imaging Technology & Informatics (MITI) Southern

2/14/2019

25

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Insufficient Bed Overlap

73

Medical Imaging T echnology & Informatics (MIT I)

Southern Cali f o rnia Permanente Medical Group

Thank you for your attention!

INTERNATIONAL ATOMIC ENERGY AGENCY, PET/CT Atlas on Quality Control and Image Artefacts, IAEA Human Health Series No. 27, IAEA, Vienna (2014).

INTERNATIONAL ATOMIC ENERGY AGENCY, IAEA Quality Control Atlas for Scintillation Camera Systems, IAEA, Vienna (2003).

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References