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1 Chapter 01 *Lecture and Animation Outline with Anatomy & Physiology Revealed Images Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. *See separate FlexArt PowerPoint slides for all figures and tables pre-inserted into PowerPoint without notes and animations. To run the animations you must be in Slideshow View. Use the buttons on the animation to play, pause, and turn audio/text on or off. Please Note: Once you have used any of the animation functions (such as Play or Pause), you must first click on the slide’s background before you can advance to the next slide.

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Page 1: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1

Chapter 01

*Lecture and

Animation Outline

with

Anatomy & Physiology Revealed Images

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

*See separate FlexArt PowerPoint slides for all

figures and tables pre-inserted into PowerPoint

without notes and animations.

To run the animations you must be in Slideshow View. Use

the buttons on the animation to play, pause, and turn

audio/text on or off.

Please Note: Once you have used any of the animation

functions (such as Play or Pause), you must first click on the

slide’s background before you can advance to the next slide.

Page 2: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.1: Introduction

2

• Questions and observations that have led to

knowledge.

• Knowledge about structure and function of the

human body.

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1.2: Anatomy & Physiology

3

• Anatomy – the study of the structure of the human body

• Physiology – the study of the function of the human body

“The complementarity of structure and function.”

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1.3: Levels of Organization

4

• Subatomic Particles – electrons, protons, and neutrons

• Atom – hydrogen atom, lithium atom, etc.

• Molecule – water molecule, glucose molecule, etc.

• Macromolecule – protein molecule, DNA molecule, etc.

• Organelle – mitochondrion, Golgi apparatus, nucleus, etc.

• Cell – muscle cell, nerve cell, etc.

• Tissue – simple squamous epithelium, adipose tissue, etc.

• Organ – skin, femur, heart, kidney, etc.

• Organ System – skeletal system, digestive system, etc.

• Organism – the human

Page 5: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Levels of Organization

Subatomic particles

Atom

Molecule

Macromolecule

Organelle

Cell

Tissue

Organ

Organ system

Organism

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Page 6: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.1 Clinical Application

6

• Ultrasound (US)

• Magnetic Resonance Imaging (MRI)

Page 7: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Ultrasound and MRI

Page 8: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.4: Characteristics of Life (10)

8

• Movement – change in position; motion

• Responsiveness – reaction to a change

• Growth – increase in body size; no change in shape

• Respiration – obtaining oxygen; removing carbon dioxide;

releasing energy from foods

• Reproduction – production of new organisms and new cells

• Digestion – breakdown of food substances into simpler

forms

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Characteristics of Life Continued

9

• Absorption – passage of substances through membranes and

into body fluids

• Circulation – movement of substances in body fluids

• Assimilation – changing of absorbed substances into

chemically different forms

• Excretion – removal of wastes produced by metabolic

reactions

Life’s characteristics which obtain, release, and utilize energy are

largely part of metabolism (all of the chemical reactions in an

organism that support life).

Page 10: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.5: Maintenance of Life

10

• Life depends on five (5) environmental factors:

• Water

• Food

• Oxygen

• Heat

• Pressure

Page 11: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Requirements of Organisms

11

• Water

- most abundant substance in body

- required for metabolic processes

- required for transport of substances

- regulates body temperature

• Food

- provides necessary nutrients

- supplies energy

- supplies raw materials

Page 12: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Requirements of Organisms

12

• Oxygen (gas)

- one-fifth of air

- used to release energy from nutrients

• Heat

- form of energy

- partly controls rate of metabolic reactions

• Pressure

- application of force on an object

- atmospheric pressure – important for breathing

- hydrostatic pressure – keeps blood flowing

Page 13: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Homeostasis*

13

* Maintaining of a stable internal environment

• Homeostatic Control Mechanisms – monitors aspects of the

internal environment and corrects as needed. Variations are within

limits. There are three (3) parts:

• Receptor - provides information about the stimuli

• Control Center - tells what a particular value should be

(called the set point)

• Effector - elicits responses that change conditions in the

internal environment

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Homeostatic Control Mechanisms

14

Stimulus

(Change occurs

in internal

environment.) Response

(Change is corrected.)

Receptors Effectors

(muscles or glands)

Control center

(set point)

(Change is compared

to the set point.)

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Page 15: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

15

Homeostatic Control Mechanisms

Receptors

Thermoreceptors

send signals to the

control center.

too high

too low

Normal body

temperature

37°C (98.6°F)

Control center

The hypothalamus

detects the deviation

from the set point and

signals effector organs.

Control center

The hypothalamus

detects the deviation

from the set point and

signals effector organs. If body temperature

continues to drop,

control center signals

muscles to contract

Involuntarily.

Stimulus

Body temperature

rises above normal.

Effectors

Skin blood vessels

dilate and sweat glands

secrete.

Response

Body heat is lost to

surroundings, temperature

drops toward normal.

Receptors

Thermoreceptors

send signals to the

control center.

Effectors

Skin blood

vessels constrict

and sweat glands

remain inactive.

Stimulus

Body temperature

drops below normal.

Effectors

Muscle

activity

generates

body heat.

Response

Body heat is conserved,

temperature rises toward normal.

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

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16

• There are two (2) types:

• Negative feedback mechanisms

• Positive feedback mechanisms

Homeostatic Control Mechanisms

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17

Negative feedback summary:

• Prevents sudden, severe changes in the body

• Corrects the set point

• Causes opposite of bodily disruption to occur, i.e. the ‘negative’

• Most common type of feedback loop

• Examples: body temperature, blood pressure & glucose regulation,

pH of Blood, O2 & CO2 levels

Homeostatic Control Mechanisms

Page 18: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Homeostatic Control Mechanisms

18

Positive feedback summary:

• Increases (accelerates) the actions of the body

• Short-lived

• Do not require continuous adjustments

• Examples: blood clotting and child birth

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19

Animation: Positive and Negative Feedback

Please note that due to differing

operating systems, some animations

will not appear until the presentation is

viewed in Presentation Mode (Slide

Show view). You may see blank slides

in the “Normal” or “Slide Sorter” views.

All animations will appear after viewing

in Presentation Mode and playing each

animation. Most animations will require

the latest version of the Flash Player,

which is available at

http://get.adobe.com/flashplayer.

Page 20: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.6: Organization

of the Human Body

20

Thoracic cavity

Abdominal

cavity

Diaphragm

Pelvic cavity

Cranial cavity

Vertebral canal

(a)

Abdominopelvic

cavity

Abdominal

cavity

Pelvic cavity

Right pleural

cavityMediastinum

Left pleural cavityPericardial

cavityDiaphragm

Vertebral canal

Cranial cavity

Thoracic

cavity

(b)

Page 21: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.6: Organization of the Human Body

Cranial Cavity

Vertebral Canal

Page 22: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.6: Organization of the Human BodyThoracic Cavity

Diaphragm

Abdominopelvic Cavity

Abdominal Cavity Pelvic CavityMediastinum Pulmonary Cavity

Page 23: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Thoracic & Abdominal

Serous Membranes

23

Thoracic Membranes

• Visceral pleura

• Parietal pleura

• Visceral pericardium

• Parietal pericardium

• Visceral layer – covers an organ

• Parietal layer – lines a cavity or body wall

Abdominopelvic Membranes

• Parietal peritoneum

• Visceral peritoneum

Page 24: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Serous Membranes

24

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Vertebra

Azygos v.

Aorta

Esophagus

Right lung

Right atrium

of heart

Right ventricle

of heart

Visceral pleura

Pleural cavity

Parietal pleura

Sternum

Anterior

Spinal cord

Plane of

section

Mediastinum

Left lung

Rib

Left ventricle

of heart

Visceral pericardium

Pericardial cavity

Parietal pericardium

Fibrous pericardium

Vertebra

Right kidney

Aorta

Inferior

vena cava

Pancreas

Large

intestine

Liver

Gallbladder

Duodenum

Visceral peritoneum

Peritoneal cavity

Parietal peritoneumAnterior

Stomach

Costal cartilage

Rib

Large intestine

Small intestine

Spleen

Left

kidney

Spinal cordPlane of

section

Page 25: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Pleural Membranes

Visceral pleura Parietal pleura

Pleural cavity

Page 26: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Pericardium

Visceral pericardium

Pericardial cavity

Parietal pericardium

Page 27: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Peritoneum

Visceral peritoneum

Parietal peritoneum

Peritonealcavity

Lesseromentum

Mesenteryof small intestine

Greateromentum

Peritoneum

Page 28: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Organ Systems

28Skeletal system Muscular system

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Integumentary system

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Integumentary System

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Skeletal System

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Muscular System

Page 32: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Organ Systems

32Nervous system Endocrine system

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Page 33: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Nervous System

Page 34: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Endocrine System

Page 35: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Organ Systems

35Cardiovascular system

Lymphatic system

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Page 36: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Cardiovascular System

Page 37: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Lymphatic System

Page 38: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Organ Systems

38

Digestive system Respiratory system Urinary system

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Page 39: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Digestive System

Page 40: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Respiratory System

Page 41: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Urinary System

Page 42: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Organ Systems

42

Male reproductive system Female reproductive system

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Page 43: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Reproductive System

Page 44: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.7: Lifespan Changes

44

Aging occurs from the microscopic level to the

whole-body level.

Can you think of some examples?

Page 45: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

1.8: Anatomical Terminology

45

Anatomical Position – standing

erect, facing forward, upper limbs

at the sides, palms facing forward

and thumbs out

Integumentary system

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Page 46: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Anatomical Position

Page 47: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Relative Positions (1)add to your list

• Supine = on back

• Prone = on belly

Page 48: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Anatomical Terminology:Orientation and Directional Terms

48

• Terms of Relative Position (based on anatomical position):

Superior (above)/Inferior (below)

Anterior or ventral (toward the front) / Posterior or dorsal ( toward

the back)

Medial (toward the midline)/Lateral (to the sides)

Bilateral (paired structures)

Ipsilateral (same side) / Contralateral (opposite sides)

Proximal (close to point of attachment)/Distal (farther from poin of

attachment)

Superficial (close to body surface)/Deep (more internal)

Page 49: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Superior Inferior

Page 50: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Anterior Posterior(Ventral) (Dorsal)

Page 51: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Medial Lateral

Page 52: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Proximal Distal

Page 53: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Deep Superficial

Page 54: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Human / Cat Clarifications• Anterior = front, Ventral = belly

– mean the same in humans but in the cat anterior is forward and ventral faces the ground

• Posterior = rear/behind, Dorsal = back– mean the same in humans but in the cat posterior is rear and dorsal faces up

• Cranial = toward the head– which is Superior in humans, but superior is dorsal in cats

• Caudal = towards the tail– which is Inferior in humans, but inferior is ventral in cats

Page 55: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Body Sections or Planes

55

• Sagittal – divides body into left and right portions

• Mid-sagittal/Median – divides body into equal left and

right portions

• Transverse or Horizontal – divides body into superior and

inferior portions

• Coronal or Frontal – divides body into anterior and posterior

portions

Page 56: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Body Sections

56

A section along a frontal

plane

A section along a transverse

plane

A section along the

median plane

Transverse

(horizontal)

plane

Frontal

(coronal)

plane

Parasagittal

plane

Median

(midsagittal)

plane

Page 57: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Body Sections

Page 58: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Sagittal Plane

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Midsagittal Plane

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Transverse Plane

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Coronal Plane

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Oblique Plane

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Body Sections

63

(a) (b) (c)

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Other Body Sections

64

(a) (b) (c)

Cross-section

L

o

n

g

i

t

u

d

i

n

a

l

s

e

c

t

i

o

n

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Abdominal Subdivisions

65

Right

hypochondriac

region

Right

lumbar

region

Right

iliac

region

Epigastric

region

Umbilical

region

Hypogastric

region

Left

hypochondriac

region

Left

lumbar

region

Left

iliac

region

Right upper

quadrant

(RUQ)

Left upper

quadrant

(LUQ)

Right lower

quadrant

(RLQ)

Left lower

quadrant

(LLQ)

Page 66: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Rt. HypochondriacEpigastric

Lt. Hypochondriac

Rt. Lumbar Lt.Lumbar

Umbilical

Rt. Iliac Lt. IliacPelvic

Body

Regions

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Nine Abdominal Regions

Rt. Hypochondriac Lt. Hypochondriac

Rt. LumbarLt. Lumbar

Rt. Iliac Lt. Iliac

Epigastric

Umbilical

Pelvic

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Abdominal Quadrants

Upper Right Lower Right Upper Left Lower Left

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Abdominal Quadrants

Upper Right

Lower Right

Upper Left

Lower Left

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Body Regions

70

Otic (ear)

Cervical (neck)

Acromial

(point of shoulder)

Mammary (breast)

Brachial

(arm)

Antecubital

(front of elbow)

Antebrachial

(forearm)

Genital

(reproductive organs)

Cephalic (head)

Orbital (eye cavity)

Mental (chin)

Sternal

Pectoral

(chest)

Inguinal

(groin)

Coxal

(hip)

Umbilical

(navel)

Pedal (foot)

Occipital

(back of head)

Acromial

(point of shoulder)

Brachial (arm)

Dorsum (back)

Cubital (elbow)

Gluteal (buttocks)

Perineal

Femoral (thigh)

Popliteal (back of knee)

Plantar (sole)(a) (b)

Patellar

(front of knee)

Vertebral

(spinal column)

Sacral (between hips)

Lumbar

(lower back)Abdominal

(abdomen)

Carpal (wrist)

Palmar (palm)

Digital (finger)

Nasal (nose)

Oral (mouth)

Frontal (forehead)

Buccal (cheek)

Tarsal (instep)

Digital (toe)

Axillary (armpit)

Crural (leg)

Sural (calf)

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

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Abdominopelvic Region

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Back

Back Scapular region

Triangle of auscultation

Vertebral region

Sacral region

Lumbar region

Page 73: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Frontal

Mental

Nasal

Oral

Orbital

Occipital

Parietal

Temporal

Zygomatic

Buccal

Otic Facial

Cephalic

Head

Regions

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Lower Limb RegionFemoral

Patellar

Crural

Tarsal PedalDorsum of foot Digits

Calcaneal

Popliteal

Gluteal

Coxal

Popliteal

Sural

Page 75: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Neck (Cervical) Region Anterior cervical

Lateralcervical

Posterior cervical

Sternocleidomastoid

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Important Points in Chapter 1:Outcomes to be Assessed

76

1.1: Introduction

Identify some of the early discoveries that lead to our current understanding

of the human body.

1.2: Anatomy and Physiology

Explain how anatomy and physiology are related.

1.3: Levels of Organization

List the levels of organization in the human body and the characteristics of

each.

1.4: Characteristics of Life

List and describe the major characteristics of life.

Give examples of metabolism.

Page 77: PowerPoint to accompany Hole’s Human Anatomy and ...region Right lumbar region Right iliac region Epigastric region Umbilical region Hypogastric region Left hypochondriac region

Important Points in Chapter 1:Outcomes to be Assessed Continued

77

1.5: Maintenance of Life

List and describe the major requirements of organisms.

Explain the importance of homeostasis to survival.

Describe the parts of a homeostatic mechanism and explain how they

function together.

1.6: Organization of the Human Body

Identify the locations of the major body cavities.

List the organs located in each major body cavity.

Name and identify the locations of the membranes associated with the

thoracic and abdominopelvic cavities.

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Important Points in Chapter 1:Outcomes to be Assessed Continued

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Name the major organ systems, and list the organs associated with each.

Describe the general function of each organ system.

1.7: Lifespan Changes

Identify changes related to aging, from the microscopic to the whole-body

level.

1.8: Anatomical Terminology

Properly use the terms that describe relative positions, body sections, and

body regions.