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Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and Humans Passorn Wonnapinij, Patrick F. Chinnery, David C. Samuels The American Journal of Human Genetics Volume 86, Issue 4, Pages 540-550 (April 2010) DOI: 10.1016/j.ajhg.2010.02.023 Copyright © 2010 The American Society of Human Genetics Terms and Conditions

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Page 1: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and Humans 

Passorn Wonnapinij, Patrick F. Chinnery, David C. Samuels 

The American Journal of Human Genetics Volume 86, Issue 4, Pages 540-550 (April 2010)

DOI: 10.1016/j.ajhg.2010.02.023

Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 2: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 1

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 3: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 2

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 4: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 3

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 5: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 4

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 6: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 5

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 7: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 6

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 8: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 7

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions

Page 9: Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and

Figure 8

The American Journal of Human Genetics 2010 86, 540-550DOI: (10.1016/j.ajhg.2010.02.023) Copyright © 2010 The American Society of Human Genetics Terms and Conditions