primary care for incarcerated transgender women lori kohler, md associate clinical professor...
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PRIMARY CARE FOR PRIMARY CARE FOR INCARCERATED INCARCERATED TRANSGENDER WOMENTRANSGENDER WOMEN
Lori Kohler, MDAssociate Clinical ProfessorDepartment of Family and Community MedicineUniversity of California, San Francisco
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PRIMARY CARE FOR INCARCERATEDTRANSGENDER WOMEN
Clinical Background Who is Transgender Barriers to Care Transgender Women and HIV California Department of Corrections
Gender Program Hormone Treatment and Management Surgical Options and Post-op care
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Clinical Experience
Tom Waddell Health Center Transgender Team
Family Health Center
Phone and e-mail Consultation
California Medical Facility-Department of Corrections
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TRANSGENDER
refers to a person who is born with the genetic traits of one gender but the internalized identity of another gender
The term transgender may not be universally accepted. Multiple terms exist that vary based on culture, age, class
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The goal of treatment
for transgender people is to improve their quality of life by
facilitating their transition to a physical state that more closely represents their sense of themselves
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Transgender Terminology
Male-to-female (MTF)
Born male, living as female
Transgender woman
Female-to-male (FTM)
Born female, living as male
Transgender man
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Transgender Terminology Pre-op or preoperative
A transgender person who has not had gender confirmation surgery
A transgender woman who appears female but still has male genitaliaA transgender man who appears male but still has female genitalia
Post-op or post operative A transgender person who has had gender confirmation surgery
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What is the Diagnosis?
DSM-IV: Gender Identity Disorder
ICD-9: Gender Disorder, NOS
Hypogonadism
Endocrine Disorder, NOS
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DSM-IV 302.85 Gender Identity Disorder
A strong and persistent cross-gender identification
Manifested by symptoms such as the desire to be and be treated as the other sex, frequent passing as the other sex, the conviction that he or she has the typical feelings and reactions of the other sex
Persistent discomfort with his or her sex or sense of inappropriateness in the gender role
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DSM-IV Gender Identity Disorder (cont)
The disturbance is not concurrent with a physical intersex condition
The disturbance causes clinically significant distress or impairment in social, occupational, or other important areas of functioning
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Transgenderism
Is not a mental illness
Cannot be objectively proven or confirmed
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Barriers to Medical Care for Transgender People
Geographic Isolation
Social Isolation
Fear of Exposure/Avoidance
Denial of Insurance Coverage
Stigma of Gender Clinics
Lack of Clinical Research/Medical Literature
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Provider ignorancelimits access to care
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Regardless of their socioeconomic status all transgender people are medically underserved
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Urban Transgender Women
Studies in several large cities have demonstrated that transgender women are at especially high risk for:
Poverty HIV disease Addiction Incarceration
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San Francisco Department of Public Health Transgender Community Project Clements, et al 1997
392 MTF participants 80% sex work 65% H/O incarceration 31% incarcerated in past year 13% with college degree Median Monthly income $744 47% homeless 2/3 of African Americans HIV+
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Limited access to Medical Care for
TransgenderPeople
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Limited access to Medical Care for
TransgenderPeople
No Transgender Education in Medical
Training
No Clinical Research
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Limited access to Medical Care for
TransgenderPeople
No Transgender Education in Medical
Training
TRANSPHOBIANo Clinical Research
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Limited access to Medical Care for
TransgenderPeople
No Transgender Education in Medical
Training
TRANSPHOBIANo Clinical Research
No Health InsuranceCoverage
No Legal Protection
Employment Discrimination
Poverty
Lack of Education
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Limited access to Medical Care for
TransgenderPeople
No Prevention Efforts
No Transgender Education in Medical
Training
TRANSPHOBIANo Clinical Research
No Health InsuranceCoverage
No Legal ProtectionNo Targeted
ProgramsFor Transgender
PeopleMental health
Substance abuse
Employment Discrimination
Poverty
Lack of Education
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Limited access to Medical Care for
TransgenderPeople
No Prevention Efforts
No Transgender Education in Medical
Training
TRANSPHOBIANo Clinical Research
No Health InsuranceCoverage
No Legal Protection
SOCIAL MARGINALIZATION
Low Self Esteem
No Targeted Programs
For TransgenderPeople
Mental healthSubstance abuse
Employment Discrimination
Poverty
Lack of Education
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Limited access to Medical Care for
TransgenderPeople
No Prevention Efforts
No Transgender Education in Medical
Training
TRANSPHOBIANo Clinical Research
No Health InsuranceCoverage
No Legal Protection
SOCIAL MARGINALIZATION
Low Self Esteem
No Targeted Programs
For TransgenderPeople
Mental healthSubstance abuse
Employment Discrimination
Poverty
Lack of Education
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HIV RISK BEHAVIOR
Sex workDrug use
Unprotected sexUnderground hormones
Sex for hormonesSilicone injections
Needle sharingAbuse by medical providers
LOW SELF ESTEEM
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Why Sex work?
Survival
Access to gainful employment
Reinforcement of femininity and attractiveness
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HIV RISK BEHAVIOR
SOCIAL MARGINALIZATION
LOW SELF ESTEEM
Sex workDrug use
Unprotected sexUnderground hormones
Sex for hormonesSilicone injections
Needle sharingAbuse by medical providers
LOW SELF ESTEEM
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HIV RISK BEHAVIOR
SOCIAL MARGINALIZATION
LOW SELF ESTEEM
INCARCERATION
Sex workDrug use
Unprotected sexUnderground hormones
Sex for hormonesSilicone injections
Needle sharingAbuse by medical providers
LOW SELF ESTEEM
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HIV RISK BEHAVIOR
SOCIAL MARGINALIZATION
LOW SELF ESTEEM
INCARCERATION
Sex workDrug use
Unprotected sexUnderground hormones
Sex for hormonesSilicone injections
Needle sharingAbuse by medical providers
LIMITED ACCESS TO
MEDICAL CARE
LOW SELF ESTEEM
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Limited access to Medical Care for
TransgenderPeople
No Prevention Efforts
No Transgender Education in Medical
Training
TRANSPHOBIANo Clinical Research
No Health InsuranceCoverage
No Legal Protection
SOCIAL MARGINALIZATION
Low Self Esteem
HIV Risk Behavior
No Targeted Programs
For TransgenderPeople
Mental healthSubstance abuse
Employment Discrimination
Poverty
Lack of Education
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Access to Medical Care for
TransgenderPeople
Prevention Efforts
Transgender Education in Medical
Training
TRANSGENDERAwareness
Clinical Research
Health InsuranceCoverage
Legal Protection
SOCIAL INCLUSION
Self Esteem
HIV Risk Behavior
Targeted Programs
For TransgenderPeople
Mental healthSubstance abuse
Employment
Self-sufficiency
Education
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HIV RISK BEHAVIOR
SOCIAL INCLUSION
SELF ESTEEM
INCARCERATION
Sex WorkDrug use
Unprotected sexUnderground hormones
Sex for hormonesSilicone injections
Needle sharingAbuse by medical providers
ACCESS
TO MEDICAL
CARE
SELF ESTEEM
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Access to Cross-Gender Hormones can:
Improve adherence to treatment of chronic illness
Increase opportunities for preventive health care
Lead to social change
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Transgender Women Need
Improved access to medical care, including hormones and surgery
Social support and inclusion
Job training and education
Culturally appropriate substance abuse treatment
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Transgender Women Need
Legal Protection
Research to assess ways to reduce recidivism
Self esteem building
Targeted prevention efforts that address the social context that leads to diminished health and well-being
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Hormone Therapy for Incarcerated Persons-HBIGDA 2001
People with GID should continue to receive hormone treatment and monitoring
Prisoners who withdraw rapidly from hormone therapy are at risk for psychiatric symptoms
Housing for transgender prisoners should take into account their transition status and their personal safety
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Torey South v. California Department of Corrections, 1999
Transgender inmate on hormones since adolescence
Hormones were discontinued during incarceration
Represented by law students at UC Davis
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T. South v. CDOC, 1999
US District Court:
Prison officials violated South’s constitutional right to be free of cruel and unusual punishment by deliberately withholding necessary medical care
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Gender Program, CMF
Gender Clinic
Transgender support group
Harm reduction education by inmate peer educators
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Gender Clinic, CMF 7/00-5/04
250+ unduplicated patients250+ unduplicated patients
25 patient encounters/session, avg.
700 patient encounters
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Gender Clinic, CMF
5 new patients/session, avg.
Inmates transported from other facilities for consultation
>95% of patients evaluated receive hormones
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Gender Clinic, CMF
50-70 inmates receiving feminizing hormones
60-70% HIV+
Majority are people of color
Majority committed nonviolent crimes
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Transgender Inmates:Commitment Offenses 10/02
CRIME %
BURG,THEFT,OTHER PROPERTY 36
ROBBERY 15
DRUG OFFENSES 11
PROSTITUTION 11
ASSAULT DEADLY WEAPON 9
MURDER 9
“OTHER” SEX CRIMES 6.7
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Identification of Transgender Inmates-Challenges
Hormones as income or barter
Secondary gain in a man’s world
Temporary loss of social stigma and separation from family influence
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Identification of Transgender Inmates-Challenges
Strict grooming standards No access to usual feminizing
accessories No access to evidence of usual
appearance No friends or family to support
patient identity
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Identification of Transgender Inmates-Challenges
The grapevine impedes clinician use of consistent subjective tests, lines of questioning
The grapevine creates competition and influences treatment choices
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Initial Visits
Review history of gender experience
Document prior hormone use
Obtain sexual history
Order screening laboratory studies
Review patient goals
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Initial Visits
Address safety concerns Assess social support system Assess readiness for gender
transition Review risks and benefits of
hormone therapy Obtain informed consent Provide referrals
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Physical Exam
Assess patient comfort with P.E.
Problem oriented exam only
Avoid satisfying your curiosity
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Male to Female Treatment Options
No hormones
Estrogens
Antiandrogen
ProgesteroneNot usually recommended except for weight maintenance
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Estrogen Premarin
1.25-10mg po qd or divided as bid
Ethinyl Estradiol (Estinyl) 0.1-1.0 mg po qd
Estradiol Patch 0.1-0.3mg q3-7 days
Estradiol Valerate injection 20-60mg IM q2wks
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Hormones in Prison
Estradiol injections only, no po-
Estradiol Valerate 20-60mg IM q2wk
Non negotiable forms avoid use of hormones as barter
Provide hormones despite prior use-
Increase opportunities for education
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Transgender Hormone Therapy
Heredity limits the tissue response to hormones
More is not always better
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Hormones
are not the cause of every medical problem reported by transgender people
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Estrogen Treatment May Lead To
Breast Development Redistribution of body fat Softening of skin Emotional changes Loss of erections Testicular atrophy Decreased upper body strength Slowing of scalp hair loss
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Risks of Estrogen Therapy Venous thrombosis/emboliVenous thrombosis/emboli (po) HypertriglyceridemiaHypertriglyceridemia (po) Weight gain Decreased libido Elevated blood pressure Decreased glucose tolerance Gallbladder disease Benign pituitary prolactinoma
(rare) Breast cancer(?)
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Spironolactone
50-150 mg po bid
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Spironolactone May Lead To
Modest breast development
Softening of facial and body hair
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Risks of Spironolactone
Hyperkalemia
Hypotension
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Women over 40 years old Add ASA to regimen
Transdermal or IM estradiol to reduce the risk of thromboemboli
Minimize maintenance dose of estrogen
Testosterone for libido as needed
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HIV and HORMONES There are no significant drug
interactions with drugs used to treat HIV
Several HIV medications change the levels of estrogens
Cross gender hormone therapy is not contraindicated in HIV disease at any stage
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Drug InteractionsEstradiol, Ethinyl Estradiol, levels areDECREASED by:
LopinavirLopinavir CarbamazepineNevirapineNevirapine PhenytoinRitonavirRitonavir PhenobarbitalNelfinavirNelfinavir Phenylbutazone
SulfinpyrazoneBenzoflavoneSulfamidine
Rifampin Naphthoflavone Progesterone Dexamethasone
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Drug InteractionsEstradiol, Ethinyl Estradiol levels areINCREASEDby:
NefazodoneNefazodone IsoniazidFluvoxamine FluoxetineIndinavirIndinavir EfavirenzEfavirenzSertraline ParoxetineDiltiazem VerapamilCimetidine AstemizoleItraconazole KetoconazoleFluconazole MiconazoleClarythromycin ErythromycinGrapefruit TriacetyloleandomycinAmprenavirAmprenavir FosamprenavirFosamprenavirAtazanavirAtazanavir
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Drug Interactions
Estrogen levels are DECREASED by:
Smoking cigarettes Nelfinavir Nevirapine Ritonavir
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Drug Interactions
Estrogen levels are INCREASED by:
Vitamin C
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Screening Labs for MTF Patients
CBC Liver Enzymes Lipid Profile Renal Panel Fasting Glucose Testosterone level Prolactin level
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Follow-up labs for MTF Patients
Repeat labs at 3, 6 months and 12 months after initiation of hormones and annually
Lipids
Renal panel (if taking spironolactone)
Liver panel (if taking po estrogen)
Prolactin level annually for 3 years
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Follow-Up Care for MTF Patients Assess feminization Review medication use Monitor mood cycles and adjust
medication as indicated Discuss social impact of transition Counsel regarding sexual activity Follow up labs Discuss safety concerns/domestic
violence
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Health Care Maintenance for MTF Patients
Instruction in self breast exam and care
Mammography – after 10+ years
Prostate screening?
STD screening
Beauty tips
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Morbidity and Mortality in Transexual Subjects Treated with Cross-Sex HormonesVan Kestern, et.al., Clinical Endocrinology, 1997
Retrospective study of 816 MTF and 293 FTM transexuals treated between 1975 and 1994
Outcome measure: Standardized mortality and incidence ratios calculated from the Dutch population
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Morbidity and Mortality (cont)
Results In both MTF and FTM transexuals,
total mortality was not higher than in the general population
Venous thromboembolism was the major complication in MTF patients treated with oral estrogens
No serious morbidity was observed that could be related to androgen treatment in FTM patients
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Gender Program Development
Medical staff training and collaboration Consistent delivery of care Privacy during clinic visits Collaboration with mental health
providers Parole planning and referral Duplication of model in other
correctional facilities Realistic HIV prevention efforts
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Summary
All transgender people are medically underserved
Hormone treatment is not optional for transgender people and contributes to improved quality of life
There are many unanswered questions about long term effects of hormone therapy but the benefits outweigh the risks for most patients
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Summary Inclusion of transgender issues in medical
training and health promotion efforts is the only ethical and compassionate option
Transgender women are at increased risk for incarceration. Programs to address their needs in correctional facilities must be developed
People who work in HIV prevention and care have unique opportunities to improve the lives transgender people
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Selected On-line Resources
• www.hbigda.org
The Harry Benjamin website• www.symposium.com/ijt/
International Journal of Transgenderism• www.lorencameron.com
Photos of FTMs • www.lynnconway.com
Photos of MTFs, FTMs and much more
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To Contact Me
• Email: [email protected]• Phone: (415)206-4941• Pager: (415)719-7329• Mailing Address:
Department of Family and Community Medicine
995 Potrero Ave.Ward 83San Francisco, CA 94110