prior areas of nia-supported space-related health research nia and nasa have collaborated on...
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Prior Areas of NIA-SupportedSpace-Related Health Research
NIA and NASA have collaborated on numerous research activities since 1989.• NIH representative and former chair, NASA Life and Microgravity Sciences and
Applications Advisory Committee
• Co-chair of NASA/NIH Collaborations Committee with Director, National Institute of Deafness and Other Communications Disorders
• Joint sponsor of workshops focusing on the aging process and changes induced by space
• NEUROLAB - Trans-NIH Research Initiative - Exercise Guide
Presenter: Dr. Richard Hodes, DirectorAgency/Organization: National Institute on Aging - NIH
National Institute on Aging
NEUROLABNEUROLAB
• Used the Spacelab module Used the Spacelab module to conduct integrated to conduct integrated neuroscience and neuroscience and behavioral researchbehavioral research
• Project included national Project included national and international partners and international partners
– Several NIH institutesSeveral NIH institutes
– Other federal agencies Other federal agencies
– International agenciesInternational agencies
Launch Date: October 29, 1998Crew: 7 Duration: 9 days
National Institute on Aging
Prior Areas of NIA-SupportedSpace-Related Health Research
NEUROLAB cont.
• Medical research included battery of tests on how the absence of gravity affects:
– Balance and perception
– Immune system response
– Bone and muscle density
– Metabolism and blood flow
– Sleep
National Institute on Aging
Prior Areas of NIA-SupportedSpace-Related Health Research
Trans-NIH Research Initiative (PA-AG00-088): “Earth-Based Research Related to Space Environment”
NIA-supported research:
• Study to characterize the normal degradation in balance control using the Baltimore Longitudinal Study on Aging cohort
• Study of enzyme serotonin-N-acetyltransferase, regulation of melatonin, and basic sleep pattern
• Study of interstitial fluid flow and bone remodeling
National Institute on Aging
Prior Areas of NIA-SupportedSpace-Related Health Research
An NIA-NASA Collaboration
Exercise: A Guide from the National Institute on Aging
• NASA provided funds to print additional copies of the guide and both agencies have posted the guide on their home pages
• Currently available on NIA and NASA Web sites
http://weboflife.arc.nasa.gov
http://www.nih.gov/nia/health/pubs/nasa-exercise
E xe r c i s e :E xe r c i s e :A G u i d e f romt h e N a t i o n a l
I n s t i t u t eo n A g i n g
National Institute on Aging
Promising Areas for NIA Space-Related Health Research Collaborations
Space vs. Ground-Based Research in Aging
• Bone and Muscle Loss Age- and space-related bone loss seem to have some similar
causes: reduced loads due to reduced physical activity or lack of gravitational forces, hormonal changes, and reduced calcium absorption by the intestines.
• Sleep and Circadian Rhythms Aging often results in disrupted sleep patterns. On the orbiting
space station, a new sunrise occurs with each 90-minute orbit.
National Institute on Aging
NIA Resources to Facilitate Potential Space-Related Health Research
• NIA cohorts such as the Baltimore Longitudinal Study on Aging
• NIA murine models of aging
National Institute on Aging