probiotics: bacteria as medicine?. so, what are they? “ live microorganisms, which, when...
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Probiotics:Bacteria as Medicine?
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So, what are they?
“Live microorganisms, which, when administered in adequate amounts, confer a health benefit to the host."
– The Food and Agriculture Organization of the United Nations (FAO)
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Most common Probiotics
Bifidobacteria
Lactobacillus
Acidophilus
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Common Probiotics
Bifidobacteria • Digest oligosaccharides from breast milk, plants• Help with peristalsis, IBS, dental cavities, serum
lipids, glucose tolerance
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Common ProbioticsLactobacillus• Found in fermented dairy products• Anti-carcinogenic • Treating and preventing infections • IBS• Diarrhea• Lactose intolerance• Skin disorders
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Common ProbioticsAcidophilus bifidus • Lowers cholesterol • Reduces growth of hostile yeasts
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Related Terms
Prebiotic: Promote growth and maintenance of beneficial or commensal microorganisms
Synbiotic: Has the properties of both a probiotic and a prebiotic
Amphibiotic: A probiotic bacteria that also targets and kills pathogenic bacteria in the body
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What do they do for us?
Intestinal microflora aid in: • Digestion • Synthesis of vitamins, hormones • Metabolism of some medications• Gut development and function• Immune system enhancement and function• Brain Development• Reducing Inflammation
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How do we get them?
• Trans-placental Transfer• Vaginal Birth• Breast milk• Diet• Environmental Exposure
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Risk Factors
• C-section• Not breastfeeding• Prematurity • Poor food choices • Chronic stress/anxiety • Antibiotic overuse, other drugs
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Which means….
• Diarrhea• Muscle pain• Fatigue• Allergic Reactions• Autoimmune disorders• Infection
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Listen to Your Gut
1. They are key for immune function2. They might lower your cholesterol3. They produce anti inflammatory molecules4. They enhance your antioxidants5. They could impact your mental health 6. Linked to obesity
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So how do we harness these unsung heroes of the intestine?
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1. Boost your fiber intake2. Eat a well balanced diet:
↑F&V ↓Sugar ↓Red meat & Sat.Fat3. Add dietary sources of probiotics4. Consider (with caution) prebiotic / probiotic
supplements
What You Can Do
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Polyphenols
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The Probiotic Process
When making probiotics:• Sudden freezing → damage to cell walls,
intercellular structures• Oxygen and moisture → bacteria die• Many bacteria degraded in acidic stomach
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In Conclusion
• Probiotics generally believed to be safe• AAP supports administration for treatment of
acute gastroenteritis and prevention of antibiotic associated diarrhea
• Decreased incidence of NEC in preterm infants after breastfeeding (synbiotic) and probiotics
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Considerations
• Look for USP seal • Compare genus, strain, and species to studies• Determine species specific to condition• Populations to be especially careful when
considering probiotics:– Children, pregnant women, elderly people, and
people with compromised immune systems
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More Research Required….
In all cases proposed as health claims to the European Food Safety Authority, the scientific evidence remains insufficient to prove cause and effect relationship between consumption of probiotic products and any health benefit
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