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4 th International Congress of Serbian Society of Mechanics June 4-7, 2013, Vrnjačka Banja PROCEEDINGS Editors Stevan Maksimović Tomislav Igić Nataša Trišović

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Page 1: PROCEEDINGS - Profesor Onlineis.fink.rs/podaci/Aleksandar_Nikolic/119/M1-13_BLAGOJEVIC_ROLE O… · These proceedings contains the papers presented at the Forth ... Learning Motion

4th International Congress of Serbian Society of Mechanics June 4-7, 2013, Vrnjačka Banja

PROCEEDINGS

Editors Stevan Maksimović

Tomislav Igić Nataša Trišović

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Vrnjačka Banja, Serbia, June 4-7, 2013 4th International Congress of Serbian Society of Mechanics

Editors Prof. Dr. Stevan Maksimović Prof. Dr. Tomislav Igić Doc. Dr. Nataša Trišović Computer editing Ivana Ilić, Marija Blažić, Marko Bojanić, Bojan Međo

Press "Beotele Prom", Beograd Circulation 200 copies

CIP

CIP - Каталогизација у публикацији Народна библиотека Србије, Београд 531/534(082) SERBIAN Society of Mechanics (Beograd). International Congress (4 ; 2013 ; Vrnjačka Banja) Proceedings / 4th International Congress of Serbian Society of Mechanics, 4-7th June, 2013, Vrnjačka Banja ; editors Stevan Maksimović, Tomislav Igić and Nataša Trišović. - Belgrade : Serbian Society of Mechanics, 2013 (Beograd : Beotele Prom). - XXIV, 1010 str. : ilustr. ; 25 cm Tiraž 200. - Str. III: Preface / S. [Stevan] Maksimović & T. [Tomislav] Igić. - Registar. - Bibliografija uz svaki rad. ISBN 978-86-909973-5-0 a) Механика – Зборници COBISS.SR-ID 198308876

Published by Serbian Society of Mechanics, Belgrade

http://www.ssm.org.rs/

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PREFACE These proceedings contains the papers presented at the Forth (29th Yu) International Congress of Serbian Society of Mechanics held in Vrnjačka Banja during the period 4th – 7th June, 2013. Theoretical and Applied Mechanics is a subject of great importance in the developing of science and technology. The aim of the Congress is to provide a forum to exhibit the progress in this field during the past years and a place to further the interaction between of modern theoretical and applied mechanics, as well as modern engineering sciences. The papers, contributed by authors from all around the globe, have been separated into 7 sections which cover the main areas of interest: `Plenary Lectures`, Section A, Section B, Section C, Section D and two Mini-symposia. We would like to express our gratitude to all members of the Scientific Committee and also to the participants for their engagement in organizing of the Congress, including the preparation of manuscripts to be published in the Journal Theoretical and Applied Mechanics, Scientific Technical Review and Journal of Serbian Society for Computational Mechanics. It gives us great pleasure to express our deep appreciation for the great long-standing support that Prof. Dr. Nikola Hajdin, President of the Serbian Academy of Sciences and Arts, has given to the promotion of all aspects of theoretical and applied mechanics in Serbia. Last, the Congress organizing committee wishes to acknowledge the collaboration of the Ministry of Education, Science and Technological Development of the Republic of Serbia, Serbian Academy of Sciences and Arts, Municipality Vrnjačka Banja and many supporting members of the Serbian Society of Mechanics.

S. MAKSIMOVIĆ & T. IGIĆ June, 2013

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Scientific Committee Nikola Hajdin (Belgrade, Serbia) Miloš Kojić (Kragujevac, Serbia) Vladan Đorđević (Belgrade, Serbia), Božidar Vujanović (Novi Sad, Serbia) Đorđe Zloković (Belgrade, Serbia) Felix Chernousko (Moscow, Russia) Antony Kounadis (Ethens, Greece) Ingo Müller (Berlin, Germany) Đorđe Đukić (Novi Sad, Serbia) Teodor Atanacković (Novi Sad, Serbia) Ardeshir Guran (Ontario, Canada) Ranislav Bulatović (Podgorica, Montenegro) Vlado Lubarda (San Diego, CA, USA) Katica (Stevanović) Hedrih (Niš, Serbia) Anatoly M. Samoilenko (Kiev, Ukraine) Emanuel Gdoutos (Patras, Greece) Hiroshi Yabuno (Tokiyo, Japan) John Katsikadelis (Ethens, Greece) M.P.Cartmell (Glasgow, Scotland, UK) Giuseppe Rega (Roma, Italy) Jan Awrejcewicz (Lodz, Poland) J. M. Balthazar (Sao Paolo, Brazil) J. A. Tenreiro Machado (Porto, Portugal) Pauel Kraseilnikov (Moscow, Russia) Subhash C. Sinha (Auburn, Alabama) Jerzy Warminski (Lublin, Poland) Yuri Mikhilin (Kharkov, Ukraine) Vesna Milošević-Mitić (Belgrade, Serbia) Jovo Jarić (Belgrade, Serbia) Bohdana Marvalova (Czech Republic) Alexander Seyranin (Moscow, Russia) Chi Chow (Michigen, United States) Lidia Kurpa (Khrakov, Ukraine) Treinhold Kienzler (Bremen, Germany) Marina Shitikova (Russia) RadeVignjević (Cranfield, England) Andrea Carpinteri (Parma, Italy) Vlada Đurković (Belgrade, Serbia) Slobodan Stupar (Belgrade, Serbia)

Miloš Nedeljković (Belgrade, Serbia) Milorad Milovančević (Belgrade, Serbia) Zoran Rajić (Belgrade, Serbia) Nikola Mladenović (Belgrade, Serbia) Aleksandar Obradović (Belgrade, Serbia) Mihailo Lazarević (Belgrade, Serbia) Tamara Nestorović (Bohum, Germany) Strain Posavljak (Banja Luka, Republic of Srpska) Livija Cvetićanin (Novi Sad, Serbia) Ivana Kovačić (Novi Sad, Serbia) Milan Mićunović (Kragujevac, Serbia) Dragan Milosavljević (Kragujevac, Serbia) Miroslav Živković (Kragujevac, Serbia) Nenad Filipović (Kragujevac, Serbia) Vladimir Dragović (Belgrade, Serbia) Slobodanka Boljanović (Belgrade, Serbia) Vladimir Raičević (Kosovska Mitrovica, Serbia) Zoran Mitrović (Belgrade,Serbia) Predrag Kozić (Niš, Serbia) Ratko Pavlović (Niš, Serbia) Dragoslav Kuzmanović (Belgrade, Serbia) Dragoslav Šumarac (Belgrade, Serbia) Petar Mitković (Niš, Serbia) Vlastimir Nikolić (Niš, Serbia) Taško Maneski (Belgrade, Serbia) Borislav Gajić (Belgrade, Serbia) Dragan Spasić (Novi Sad, Serbia) Marina Kutin (Belgrade, Serbia) Ljubica Milović (Belgrade, Serbia) Marko Rakin (Belgrade, Serbia) Aleksandar Sedmak (Belgrade,Serbia) Dušan Najdanović (Belgrade, Serbia) Milomir Gašić (Kraljevo, Srbija) Boško Rašuo (Belgrade, Serbia) Pol Spanos (Houston, TX, USA) NatašaTrišović (Belgrade, Serbia) Tomislav Igić (Niš, Serbia) Stevan Maksimović (Belgrade, Serbia)

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Organizing Committee

Stevan Maksimović (Chairman) VTI-Aeronautical Department, Belgrade, Serbia Tomislav Igić (Chairman) Faculty of Civil Engineering, Niš, Serbia Nataša Trišović (Secretary) Faculty of Mechanical Engineering, Belgrade, Serbia Bojan Međo, Faculty of Technology and Metallurgy, Belgrade, Serbia Ivana Ilić, VTI-Aeronautical Department, Belgrade, Serbia Ivana Vasović, GOŠA Institute, Belgrade, Serbia Marija Blažić, VTI-Aeronautical Department, Belgrade, Serbia Marko Bojanić, VTI-Aeronautical Department, Belgrade, Serbia

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Table of Contents

Plenary lectures

Miloš Kojić Numerical Modeling of Convective and Diffusive Mass Transport in Biological Media 3 П.С. Красильников, А.Г. Сараева Периодические орбиты пуанкаре первого рода в плоской круговой ограниченной задаче трех тел с малым ускорением 19 Josif Vuković, Aleksandar Obradović Constraint Reactions in Optimal Control of Mechanical Systems 25 Katica (Stevanović) Hedrih Linear and Nonlinear Dynamics of Hybrid System 43 Dragan Jovanović Isodyne Stress Analysis of Stress State in Contact Regions 59 Philippe Vignal, Lisandro Dalcin, Nathan Collier, V. M. Calo Petiga: Solution of Higher-order Partial Differential Equations 71 Mohsen Razzaghi Orthogonal Functions and Hybrid Approximations for Variational Problems 81 Ardeshir Guran Adaptive Materials and Structures: An Overview 93

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Section A: General Mechanics

M. Ćurčin Accelerometer Instrumented Physical Pendulum 105 M. Živanović PD Control of Motion of a Scleronomic Mechanical System 111 N. Zorić, A. Simonović, Z. Mitrović, S. Stupar Optimal Vibration Control of Smart Composite Beams using Self-Tuning Fuzzy Logic Controller 117 O. Jeremić, M. Milinović, A. Kari Comparative Analyses of Linear and Nonlinear Serial and Redundant Links of Wire Rope Absorbers 123 P. Mandić, M. Lazarević, S. Stojanović, M. Ristanović Real Time Fractional Order Control of Rotary Inverted Pendulum 129 O. Lazarević, V. Batinić Analysis of Hydraulic Excavator Dynamic Behaviour 135 B. Sarić One Common Solution to the Singularity and Perihelion Problems 141 D. Đurić On Brachistochronic Motion of a Multibody System with Real Constraints 147 V. Vujičić Four Dimensional Spaces with Geometric and Kinematic Constraints 153 R. Radulović Shooting Method in Determining Global Minimum Time of Brachistochronic Motion 159 N. Vuković, Z. Miljković, M. Mitić, M. Petrović Learning Motion Trajectories of Differential Drive Mobile Robot Using Gaussian Mixtures and Hidden Markov Model 165

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S. Rusov, N. Mladenović, Z. Mitrović Possibility of Contact Force Optimization and Aerodynamic Noise Reduction on Overhead Equipment 171 S. Šalinić, A. Nikolić On the Free Vibration of a Multiple-Stepped Cantilever Beam 177 B. Jovanović, V. Jovanović Maupertuis Principle and Isoenergetic Integrability 183 S. Mastilović Dynamic Response of Brittle Systems in Confined Dimensions 187 V. Dragović, K. Kukić From Kowalevski Top to Jurdjevic Elasticae 193 Lj. Veljović About Kinematical Vector Rotators Defined for Rigid Body Dynamics with Coupled Rotations around Axes without Intersection 199 D. Perišić Optimal Control under Incomplete Information and Kolmogorov Equation 205 J. Otto, L. Cvetićanin, M. Zuković Application of the Theory of Meshchersky on a Practical Example 211 M. Živanović Comparative Simulation Results of Sliding Mode and PD Control of a 3-DOF Manipulator 217

Section B: Fluid Mechanics

B. Zindović, Lj. Savić, R. Kapor, N. Mladenović Comparison of Numerical and Scale Models of Stepped Spillway Flow 225 S. Ožvat, B. Mašić, G. Jeftenić, S. Kolaković, S. Vujović Friction Factor Determination in Turbulent Pipe Flow Regime 231

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D. Damljanović, B. Rašuo, A. Vitić, Đ. Vuković, J. Isaković Measurement and Analysis of Flow Angularity in the Supersonic Test Section of the T-38 Blowdown Wind Tunnel in VTI 237 R. Petrović, M. Živković, N. Todić Investigations of Flow Rate Ripple and Pressure Pulsation of Radial Piston Pump 243 D. Komarov, J. Svorcan, S. Stupar, A. Simonović, M. Stanojević Baltić Numerical Investigation of S809 Airfoil Aerodynamic Characteristics 249 G. Ocokoljić, M. Samardžić, D. Marinkovski, J. Isaković, Z. Anastasijević One-Component Transducer for Measurement of the Hinge Momoment 255 M. Samardžić, Z. Anastasijević, J. Isaković, D. Marinkovski, D. Ćurčić, B. Rašuo Usage of Semoconductor Strain Gauges in Dynamic Experiments in the T-38 Wind Tunnel 261 M. Kolarević, Lj. Savić, R. Kapor, N. Mladenović

Suprecritical Flow in Circular Closed-Conduit Bends 267 Đ. Čantrak, N. Janković Reynolds Number Influence on the Statistical Characteristics of Turbulent Swirl Flow 275 M. Kozić, S. Ristić, S. Linić Analysis of Pulverized Coal Granulation and Restitution Coefficients Impact on Coal Powder Distribution at Burners 279 D. Jerković, D. Regodić, Ž. Reljić, N. Hristov The Prediction of Axial Aerodynamic Coefficient Reduction using Base Bleed 285 S. Mandić, S. Stojković, M. Milošević Aerodynamic Configurations of the Modified Anti-Tank Missile Guided and Controled by Existing SCLOS System 291

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Section C: Mechanics of Solid Bodies

P. Smiljanić, A. Sedmak, E. Džindo Analysis of Composite Beams Materials and Adhesives 299 M. Bojanić, S. Boljanović, K. Maksimović Buckling and Postbuckling Behaviour of Layered Composite Structures by Finite Elements 305 B. Deretić Stojanović, S. Stošić, S. Kostić The Stiffness Matrix of the Fixed-End Composite Frame Element 311 J. Jarić, D. Kuzmanović, D. Šumarac On Anisotropic Elasticity Damage Mechanics 317 D. B. Jovanović Reconstruction of Strain Energy Surfaces at the Crack Tip Vicinity 323 Z. Đorđević, I. Atanasovska, M. Blagojević, D. Momčilović, M. Miletić The Numerical Analysis of Strain and Stress State of Composite Shaft 329 S. Maksimović, I. Vasović, M. Maksimović, M. Djurić Improved Computation Method to Fatigue and Fracture Mechanics Analysis of Aircraft Structures 335 N. Petrašinović, D. Petrašinović, S. Trivković, A. Simonović, S. Stupar Fatigue Crack Growth in 2024-T3 Aluminium Alloy 341 M. Nefovska Danilović, M. Petronijević, M. Radišić Transverse Vibration of Plates with Edge Beams using Spectral Element Method 347 B. N. Novaković On the Post-Critical Behaviour of an Optimaly Shaped Elastic Column with Clamped-Simply Supported Ends Positioned on Elastic Foundation 353 O. Peković, S. Stupar, A. Simonović, Z. Posteljnik Bending and Free Vibration Finite Element Analysis of Thin Composite Plates Based on Isogeometric Paradigm 359

X Y Z Sequence A1

F = 7220 daN

1 .0 41

0 .1 52

1.

0. 9

0. 8

0. 7

0. 6

0. 5

0. 4

0. 3

0. 2

0. 1

0.

I ni ci ja ln i lo m- kor ak 83 D ef or me d( 7. 292) : T ota l A nvel opa: Ma x F ail ure Ind ex. (Max . D efo r. )

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O. Ognjanović, K. Maksimović, D. Stamenković, Z. Vasić The Effects of Thermal Gradients on Stress Distributions 365 M. Mićunović, Lj. Kudrjavčeva, M. Topalović, Thermomechanics of Soft Inelastics Bodies - An Application to Asphalt Behavior 371 S. Perković, M. Blažić, S. Boljanović, I. Vasović, V. Stefanović Determination of Crack Growth Trajectory: Experimental and Numerical Comparisons 377 M. Hadžalić, S. Posavljak, N. Vukojević Analysis of Significant Parameters on Dynamic Behaviour of the Deep Mine Hoist Installations 383 A. P. Seyranian, V. B. Glavardanov On the Problem of Nicolai with Variable Cross-Section and Pre-Twisting Effect 389 M. Blažić, I. Ilić, Y. Assoul Fatigue Life Analysis for Three-Dimensional Cracked Lugs 395 M. Topalović, M. Ivanović, M. Živković, A. Dišić Comparison of FEM and SPH Methods Used for Analysis of Solid Bodies 401 B. Rakić, L. Ivanović, D. Josifović, A. Ilić Stress-Strain Analysis at Hydro Accumulator Cylinder 407 S. Ćorić , S. Brčić Investigation of the Frame Structure Stability in Elasto-Plastic Domain 413 M. Jovanović, A. Simonović, S. Stupar, N. Zorić, N. Lukić Experimental Determination of Basic Parameters for Active Vibration Control System Development 419 S. Boljanović, S. Maksimović, A. Carpinteri Crack Growth Analysis of Edge Notched Components under Cyclic Loading 425 I. Ilić, Lj. Ilić, S. Perković, M. Blažić Strength Analysis of Composite Structural Elements for Unmanned Aerial Vehicle 431 T. Igić, D. Turnić Limit Analysis, Optimum Conditions and Optimum Structural Design of Metal Shells 437

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M. Marjanović, Đ. Vuksanović Linear Analysis of Single Delamination in Laminated Composite Plate using Layerwise Plate Theory 443 Đ. Novković, N. Maričić, Z. Glavčić CFD Simulations in Small Bulb Turbine with Adjustable Runner Blades 449 R. Mandić, R. Salatić, Z. Perović, M. Marinković Experiences in the Numerical Modelling of Masonry Infilled Frames 455 S. Vasin, M. Ristić, M. Ognjanović Gear Transmission Unit Vibration Related to Design Parameters and Resonances 461 A. Grbović, G. Kastratović, N. Vidanović , B. Rašuo Review of Modern Numerical Methods for Stress Intensity Factor Determination 467 K. Maksimović , D. Stamenković, Lj. Milović Influence of Surface Crack Shape on Crack Growth Rate in Plate 473 D. Ristić, D. Milosavljević The Stress Analysis of the Spur Gears Tooth Root and its Computation Model 579 B. Škorić, M. Arsenović, M. Kutin, I. Vasović, M. Ristić, Z. Milutinović

Thermography and Numerical Simulations with Respects to Stress State and Fracture of Continuous Cast Specimens Made of Bronze Alloy 485 A. Dišić, M. Živković, V. Milovanović Numerical Determination of Parameters of Johnson-Cook Material Model 491 J. Živković, G. Jovicić, S. Vulović, Z. Stepanović, M. Živković The Numerical Assessment of the Structural Integrity of the Tibia-Implant using Failure Criteria 497 D. Rakić, M. Živković, V. Milovanović, N. Milivojević, D.Divac Stress Integration of Matsuoka-Nakai Constitutive Model Using Incremental Plasticity Method 503 V. Milovanović, G. Jovičić, M. Živković, D. Rakić, A. Dišić

Analysis of Influence Choice Fatigue Failure Criteria to Assess the Integrity of Wagon Structure Parts 509

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V. Dunić, N. Busarac, V. Slavković, N. Grujović, M. Živković, R. Slavković Partitioned Thermo-Mechanical Coupling Procedure of FEM Components 517 A. Radaković, D. Milosavljević, G. Bogdanović, Lj. Veljović Failure Analysis of a Composite Laminate Modeled Using the Higher Order Deformation Theory 523 M. Katinić, D. Kozak , N. Gubeljak , M. Rakin , B. Medjo, A. Sedmak Numerical Determination of Creep Fracture Mechanics Parameter C* For Single Edge Crack in a Plate under Tension 529 J. M. Đoković, R. R. Nikolić Crack Deflection into an Interface between the Two Orthotropic Materials 535 G. Janevski, N. Nešić, P. Kozić, I. Pavlović Transverse Vibration of a Damped Beam with One Step Change Subjected to Axial Force 541 M. Vasko, A. Guran, L. Jakubovicova, P. Kopas Effects of the Loading Rate on Contact Stresses of a Roller Bearing: A Computational Study 547 D. Karličić, R. Pavlović Effect of Pasternak Foundation on Flexural Vibration and Buckling of Symmetric Cross-Ply Laminates 553 I. Pavlović, R. Pavlović, P. Kozić, G. Janevski, I. Ćirić Stochastic Stability of a Viscoelastic Double-Beam System Under Wideband Noises 559 S. V. Đurković, V. Gobeljić, M. Ostojić, T. Nikolić Milkovski, T. Mihovilović, M. Grbić Modification of Wing Structure- Extension of Wing Walk Compound 565 N. Anđelić, V. Milošević-Mitić, T. Maneski, A. Petrović Stress Analysis of Thin-Walled Structural Elements of Turbine Blade Shape 571

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Section D: Interdisciplinary and Multidisciplinary Problems

A. Hedrih, M. Lazarević, A. Mitrović-Jovanović Fertilisation as a Biomechanical Oscillatory Phenomenon in Mamals 579

S. B. Stojanović, D. Lj. Debeljković, G. Simeunović, N. Dimitrijević Further Results on Finite-Time Stability of Singular Time-Delay Systems: Delay-Dependent Conditions 585

V. Veljić, A. Debeljković, Đ. Koruga Mechanical Properties Investigation of Commercial and Nanophotonics Soft Contact Lenses 591

V. Jazarević, B. Rašuo Computation of Acoustic Sources for the Landing Gear during the Take-Off and Landing 597

S. Đ. Mesarović, J. M. Padbidri, B. Muhunthan Micromechanics of Dilatancy, Critical State and Shear Bands in Granular Materials 603

V. Kuzmanović, Lj. Savić, N. Mladenović Thermal Behaviour and Transversal Joint Distance Computation for Gravity RCC Dams 609 M. Petronijević, M. Radišić, M. Nefovska Danilović Wave Propagation Due to a Moving Load 615

K. Velimirović, N. Velimirović Flight Performance Determinaton of The Turboprop Aircraft 621

J. Vidaković, V. Kvrgić, G. Ferenc, Z. Dančuo, M. Lazarević Kinematic and Dynamic Model of the Human Centrifuge 627

M. Milošević, V. Đurković, Z. Gajić The Influence Terrain Slope on Impact Point of Rockets Burst Launching from MLRS 633

D. Momčilović, I. Atanasovska, Lj. Milović, Z. Đorđević Assessment of the Fatigue Life Reduction of Machine Parts with Corrosion Pit 639

P. Elek, S. Jaramaz, D. Micković Fragment Shape Distribution in Explosively Driven Fragmentation 645

 

0 1 2 3 4 50.0

0.4

0.8

1.2

1.6

2.0ODM (OM UM)

a0 = 10.4 , L = 1.5 mm

a0 = 11.2 , L = 1.7 5 mm

(fina l f ract . of 2 specimens)

a0 = 12.3 , L = 1 mm

C

TO

D [m

m]

a [mm]

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R. Petrović, R. Slavković, N. Todić Influence of Improved Stator Curve on the Characteristic of Vane Pump 651

I. B. Grozdanović, N. I. Burić, K. D. Todorović, N. T. Vasović Weak and Strong Coupled Stochastic Oscillators with Delays in Coupling 657

S. Jovančić, D. Živanić, M. Milošević Random Soil Parameters Effect to the Accuracy on Rocket Impact Points of Multiple Launcher Rocket Systems 663

S. Kostić, I. Franović, K. Todorović, N. Vasović Nonlinear Dynamics of Spring-Block Earthquake Models 669

M. Mitić, Z. Miljković, N. Vuković, I. B. Lazarević Visual Control of a Mobile Robot using Homography and Learning fom Demonstration Methodology 675

Z. Dančuo, V. Kvrgić, B. Rašuo, J. Vidaković On Dynamics of a Spatial Disorientation Trainer for Pilot Training 681

K. Jovičić, R. Jovičić, M. Prokolab, B. Jegdić Integrity Assessment for Tank with Cracks in Welded Joints 687

S. Mastilović Molecular Dynamics Simulation of Nanoscale Taylor Test 693 D. Blagojević, M. Todić, O. Miletić, V. Golubović Bugarski Definition and Investigation of Operation and Nonlinear Stiffness of Pulling and Buffer Devices for Load and Relaxation Process 699

Z. Perović, D. Šumarac Elastoplastic Analysis of Trusses Subjected to Cyclic Loading 705 B. Međo, M. Rakin, N. Gubeljak, D. Kozak, I. Cvijović Alagić, A. Sedmak Influence of Welded Joint Geometry on Fracture Behaviour – Micromechanical Assessment 711

Š. M. Bajmak Influence Form Function Network Construction Pipeline in the Optimal Parameters in District Heating and Cooling 717

D. Jevtić, A. Savić Mechanical Properties of Fiber Reinforced Concrete Made with Polypropylene Fibers 723

M. Blagojević, M. Živković Development of Software Pak-M for Calculation of Magnetostatic Field 729

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Z. Vasić, V. Stefanović, P. Dragičević Practical Approach to Integrated Design of Aeronautical Composite Constructions Using Catia Software 735

N. Marković, D. Turnić , T. Igić Elasto-Plastic Behaviour and Ultimate Load of Plate Girders Subjected to Patch Loading 741

Minisymposium 1: Computational Bioengineering

B. Ćirković, V.Isailović, Ž. Milošević, A. Sofla, M. Radišić, N. Filipović Computer Simulation of Motion of Magnetic Particles in External Magnetic Field 751

D. Nikolić, S. Aleksandrić, M. Tomašević, M. Radović, V. Ranković, N. Filipović Prediction of Coronary Plaque Position on Arterys with Myocardial Bridge 757

M. Živanović, G. Bijelić, A. Savić, N. Filipović Numerical Simulation of Iontoforesis in the Drug Delivery System 763 M. Radović, M. Đoković, A. Peulić, N. Filipović Application of Data Mining Techniques for Mammogram Classification 769

T. Đukić, S. Savić, N. Filipović Computer Simulation of Motion of Solid Particles in Laminar Flow Using Strong Solid-Fluid Coupling Computational Scheme 775

L. Velicki, N. Čemerlić-Adjić, R. Jung, N. Tomić, O. Adjic, D. Nikolić, I. Saveljić, D. Milašinović, N. Filipović Evaluation of Borderline Coronary Lesions Using Noninvasive Computed Fractional Flow Reserve 781

M. Milošević, M. Kojić, N. Kojić, M. Ferrari, A. Ziemys Hierachical Model for Diffusion within Biological Media 787

R. Radaković, A. Peulić, S. Kovač, N. Filipović Electromyography Detection of Muscle Response in Musculus Quadriceps Femoris of Elite Volleyball Players on Different Training Stimuli 793 Ž. Milošević, D. Nikolić, I. Saveljić, M. Radović,T. Exarchos, O. Parodi, N. Filipović Three-Dimensional Computer Modeling of Plaque Formation and LDL Transport within Artery and through the Vessel Wall 797

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S. Jeremić, Z. Marković, V. Stepanić Investigation of Antioxidative Activity Mechanisms of Alisarine Molecule 803

N. Mijailović, S. Petrović, D. Nikolić, A. Peulić, N. Zdraković, B. Ristić, N. Filipović Non-Invasively Assessment of Knee Cartilage Stress Distribution Using Motion Capture System and Finite Element Method 809

V. Potsika, V. Protopappas, M. Vavva, K. Raum, D. Rohrbach, D. Polyzos, D.I Fotiadis

Estimation of Wave Dispersion and Attenuation for the Assessment of Healing Bones 815

M. Blagojević, A. Nikolić, M. Živković, M. Živković, G. Stanković Role of Oscillatory Shear Index in Predicting the Occurrence and Development of Plaque 821

A. Vukičević, G. Jovičić, N. Filipović Finite Element Analysis of Generic Expandable Stent Deployment: A Worst Case Scenario Prediction 825

I. Saveljić, A. Janović, D. Nikolić, Z. Rakočević, M. Đurić, N. Filipović Finite Element Analysis of the Facial Skeleton on Simulated Occlusal Loading 831

M. Obradović, N. Filipović Modeling of Axonal Elongation by Stem Cell Using Finite Element Method 837

N. Todić, N. Filipović, R. Petrović Modeling of Torque With Friction Effect for Water Hydraulic Axial Piston Pump/Motor 843

J. Đorović, Z. Marković, D. Milenković, D. Amić, S. Marković Antioxidant Activity of Quercetin: Hat versus Set-Pt Mechanism 849

D. Petrović, M. Obradović, M. Radović , A. Jovanović, S. Jovanović, D. Baloš , M. Kojić, N. Filipović

Computer Modeling of Inhibition Process in Nanocoating of Surfaces wth Nanocontainers 855

D. Milenković, Z. Marković, J Dimitrić Marković, B. Lučić DFT Investigation of the Reaction of Baicalein with Hydroxy Radical 861

F. D. Meo, E. H. Anouar, P. Podloucka, G. Fabre, I. Bayach, T. Desmier, N. Martín, V. Lemaur, K. Berka, J. Cornil, M. Otyepka, R. Lazzaroni, P. Trouillas Understanding Antioxidant Properties of Natural Compounds at the Atomic Scale 867

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D. Amić, V. Stepanić, B. Lučić, Z. Marković, J. M. Dimitrić Marković Why Does O–H Bond Dissociation Enthalpy Effectively Represent Free Radical Scavenging Activity of Flavonoids? 873

Minisymposium 2: Nonlinear Dynamics

J. Simonović, M. Cajić, D. Karličić The Forced Vibrations of Complex Circular Membrane System with Visco-Elastic Coupling 883

V. Marković, A. Stanojević, S. Maćešić, Ž. Čupić, V. Vukojević, Lj. Kolar-Anić Dynamic States of Cortisol as a Function of Cholesterol Concentration in a Model of HPA Axis Dynamics 889

B. Stanković, Ž. Čupić, N. Pejić, Lj. Kolar-Anić One Scenario for Transition from Supercritical to Subcritical Andronov-Hopf Bifurcation Point 895

I. Nuša Bubanja, S. Maćešić, J. Maksimović, M. Milenković, E. Greco, R. Cervellati, S. D. Furrow, Ž. Čupić, S. Anić, Lj. Kolar-Anić Intermittences or Bursting Oscillations in Briggs-Rauscher Oscillating System 899

R. Radulović, A. Obradović, B. Jeremić Brachistochronic Motion of a Nonholonomic Mechanical System with Limited Reaction of Constraints 903

Z. Rakarić, I. Kovačić Bursting Oscillations in a Single Degree of Freedom Nonlinear Oscillator 909

A. Đurić, M. Filipović, W. Chen Vizualiaztion of the Three Critical Spaces Related to the 6-DOF Machinery 915

D. Milosavljević, G. Bogdanović, Lj. Veljović, A. Radaković Bulk Waves in Fibre Reinforced Materials 921

G. Bogdanović, D. Milosavljević, Lj. Veljović, A. Radaković Wave Propagation in Orthotropic Materials 927 Lj. Veljović, D. Milosavljević, G. Bogdanović, A. Radaković About Rigid Body Oscillations around Two Inclined Axes without Intersection 933

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M. Ugrčić Finite Element Modeling of Wing-Bird Strikes 939 N. Potkonjak, D. Minić, Lj. Kolar-Anić, Z. Nikolić, S. Anić Nonlinear Phenomena of Electrochemical System Pertubated by Current Interrupt Technique 945

M. Cajić, D. Karličić, M. Lazarević The State Space Model of a Single-Link Flexible Robot with a Fractional Order Viscoelastic Element in the Joint 949

Lj. Kevac, A. Đurić, M. Filipović Relation between Cable-Suspended Parallel Robot and Classic Robotic Structure 955

V. Veljić, A. Debeljković, Đ.Koruga Study of Mechanical Properties of Commercial and Nanophotonics Soft Contact Lenses by Optomagnetic Spectroscopy 961

J. Simonović Stability Analysis of Stationary Regimes in Transverse Oscillations of Coupled Plate System 967

M. Marjanov Unstable Orbits in the Solar System 973 M. Stamenković, M. Mikić Testing of Singularity and Position of Non-Linear Dynamics Relative Equilibrium of Heavy Material Particle on Eccentrically Rotating Rough Circle Line, with Constant Angular Velocity 983

M. Vukčević Dynamic of Different Structures of Galaxies - Necessary Conditions for Stable Nonlinear Structures 989

S. N. Blagojević, Ž. Čupić, S. M. Blagojević, Lj. Kolar Anić Dynamical System Analysis for the BrayLiebhafsky Reaction under CSTR Conditions 995

B. Adnađević, T. Đajić, J. Jovanović The Dispersive Isothermal Kinetics of Nicotinamide Release from Poly (Acrylic-Co-Methacrylic Acid) Xerogel 999

N. Trišović Wavelet Families - A Primer 1005

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Author Index

Adnađević B., 999 Ađić O., 781 Aleksandrić S., 757 Amić D., 849, 873 Anastasijević Z., 255, 261 Anđelić N., 571 Anić S., 899, 945 Anouar E.H. 867 Arsenović M., 485 Assoul Y., 395 Atanasovska I., 329, 639 Bajmak Š., 717 Baloš D., 855 Batinić V., 135 Bayach I., 867 Berka K., 867 Bijelić G., 763 Blagojević D., 699 Blagojević Milan 729, 821 Blagojević Mirko 329 Blagojević S. M. 995 Blagojević S. N. 995 Blažić M., 377, 395, 431 Bogdanović G., 523, 921, 927, 933 Bojanić M., 305 Boljanović S., 305, 377, 425 Brčić S., 413 Burić N., 657 Busarac N., 517 Cajić M., 883, 949 Calo V.M., 71 Carpinteri A., 425 Cervellati R., 899 Chen W., 915 Collier N., 71 Cornil J., 867 Cvetićanin L., 211 Cvijović-Alagić I., 711 Čantrak Đ., 275

Čemerlić-Ađić N., 781 Čupić Ž., 889, 895, 899, 995 Ćirić I., 559 Ćirković B., 751 Ćorić S., 413 Ćurčić D., 261 Ćurčin M., 105 Dalcin L., 71 Damljanović D., 237 Dančuo Z., 627, 681 Debeljković A., 591, 961 Debeljković D., 585 Deretić Stojanović B., 311 Desmier T., 867 Dimitrić Marković J., 861, 873 Dimitrijević N., 585 Dišić A., 401, 491, 509 Divac D., 503 Dragičević P., 735 Dragović V., 193 Dunić V., 517 Džindo E., 299 Đajić T. 999 Đoković J., 535 Đoković M., 769 Đorđević Z., 329, 639 Đorović J., 849 Đukić T., 775 Đurić A., 915, 955 Đurić D., 147 Đurić Marija, 831 Đurić Mirjana, 335 Đurković S., 565 Đurković V., 633 Elek P., 645 Exarchos T., 797 Fabre G., 867 Ferenc G., 627 Ferrari M., 787

Filipović M., 915, 955 Filipović N., 751, 757, 763, 769, 775, 781, 793, 797, 809, 825, 831, 837, 843, 855 Fotiadis D., 815 Franović I., 669 Furrow S., 899 Gajić Z., 633 Glavardanov V., 389 Glavčić Z., 449 Gobeljić V., 565 Golubović Bugarski V., 699 Grbić M., 565 Grbović A., 467 Greco E., 899 Grozdanović I., 657 Grujović N., 517 Gubeljak N., 529, 711 Guran A., 93, 547 Hadžalić M., 383 Hedrih A., 579 Hristov N., 285 Igić T., 437, 741 Ilić A., 407 Ilić I., 395, 431 Ilić Lj., 431 Isailović V., 751 Isaković J., 237, 255, 261 Ivanović L., 407 Ivanović M., 401 Jakubovicova L., 547 Janevski G., 541, 559 Janković N., 275 Janović A., 831 Jaramaz S., 645 Jarić J., 317 Jazarević V., 597 Jeftenić G., 231 Jegdić B., 687 Jeremić B., 903

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Jeremić O., 123 Jeremić S., 803 Jerković D., 285 Jevtić D., 723 Josifović D., 407 Jovančić S., 663 Jovanović A., 855 Jovanović B., 183 Jovanović D., 59, 323 Jovanović J., 999 Jovanović M., 419 Jovanović S., 855 Jovanović V., 183 Jovičić G., 497, 509, 825 Jovičić K., 687 Jovičić R., 687 Jung R., 781 Kapor R., 225, 267 Kari A., 123 Karličić D., 553, 883, 949 Kastratović G., 467 Katinić M., 529 Kevac Lj., 955 Kojić M., 3, 787, 855 Kojić N., 787 Kolaković S., 231 Kolar Anić Lj., 995, 889, 895, 899, 945 Kolarević M., 267 Komarov D., 249 Kopas P., 547 Koruga Đ., 591, 961 Kostić Srđan, 669 Kostić Svetlana, 311 Kovač S., 793 Kovačić I., 909 Kozak D., 529, 711 Kozić M., 279 Kozić P., 541, 559 Красильников П.С., 19 Kudrjavceva Lj., 371 Kukić K., 193 Kutin M., 485 Kuzmanović D., 317 Kuzmanović V., 609 Kvrgić V., 627, 681 Lazarević I., 675

Lazarević M., 129, 579, 627, 949 Lazarević O., 135 Lazzaroni R., 867 Lemaur V., 867 Linić S., 279 Lučić B., 861, 873 Lukić N., 419 Maćešić S., 889, 899 Maksimović J., 899 Maksimović K., 305, 365, 473 Maksimović M., 335 Maksimović S., 335, 425 Mandić P., 129 Mandić R., 455 Mandić S., 291 Maneski T., 571 Maričić N., 449 Marinković M., 455 Marinkovski D., 255, 261 Marjanov M., 973 Marjanović M., 443 Marković N., 741 Marković S., 849 Marković V., 889 Marković Z., 803, 849, 861, 873 Martín N., 867 Mastilović S., 187, 693 Mašić B., 231 Medjo B., 529, 711 Meo F.D.. 867 Mesarović S., 603 Micković D., 645 Mićunović M., 371 Mihovilović T., 565 Mijailović N., 809 Mikić M., 983 Milašinović D., 781 Milenković D., 849, 861 Milenković M., 899 Miletić M., 329 Miletić O., 699 Milinović M., 123 Milivojević N., 503 Milosavljević D., 479, 523, 921, 927, 933

Milošević Milan, 291, 633, 663 Milošević Miljan, 787 Milošević Ž., 751, 797 Milošević-Mitić V., 571 Milovanović V., 491, 503, 509 Milović Lj., 473, 639 Milutinović Z., 485 Miljković Z., 165, 675 Minić D., 945 Mitić M., 165, 675 Mitrović Z., 117, 171 Mitrović-Jovanović A., 579 Mladenović N., 171, 225, 267, 609 Momčilović D., 329, 639 Muhunthan B., 603 Nefovska Danilović M., 347, 615 Nešić N., 541 Nikolić A., 177, 821 Nikolić D., 757, 781, 797, 809, 831 Nikolić R., 535 Nikolić Z., 945 Nikolić Milkovski T., 565 Novaković B., 353 Novković Đ., 449 Nuša Bubanja I., 899 Obradović A., 25, 903 Obradović M., 837, 855 Ocokoljić G., 255 Ognjanović M., 461 Ognjanović O., 365 Ostojić M., 565 Otto J., 211 Otyepka M., 867 Ožvat S., 231 Padbidri J., 603 Parodi O., 797 Pavlović I., 541, 559 Pavlović R., 553, 559 Pejić N., 895 Peković O., 359 Perišić D., 205 Perković S., 377, 431

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Perović Z., 455, 705 Petrašinović D., 341 Petrašinović N., 341 Petronijević M., 347, 615 Petrović A., 571 Petrović D., 855 Petrović M., 165 Petrović R., 243, 651, 843 Petrović S., 809 Peulić A., 769, 793, 809 Podloucka P., 867 Polyzos D., 815 Posavljak S., 383 Posteljnik Z., 359 Potkonjak N., 945 Potsika V., 815 Prokolab M., 687 Protopappas V., 815 Radaković A., 523, 921, 927, 933 Radaković R., 793 Radišić Marko, 615 Radišić Milica, 751 Radišić Mirko, 347 Radović M., 757, 769, 797, 855 Radulović R., 159, 903 Rakarić Z., 909 Rakić B., 407 Rakić D., 503, 509 Rakin M., 529, 711 Rakočević Z., 831 Ranković V., 757 Rašuo B., 237, 261, 467, 597, 681 Raum K., 815 Razzaghi M., 81 Regodić D., 285 Reljić Ž., 285 Ristanović M., 129 Ristić B., 809 Ristić D., 479 Ristić Marko 485 Ristić Miloš 461 Ristić S., 279 Rohrbach D., 815 Rusov S., 171

Salatić R., 455 Samardžić M., 255, 261 Сараева А.Г. 19 Sarić B., 141 Saveljić I., 781, 797, 831 Savić A., 723, 763 Savić Lj., 225, 267, 609 Savić S., 775 Sedmak A., 299, 529, 711 Seyranian A., 389 Simeunović G., 585 Simonović A., 117, 341, 359, 419 Simonović J., 883, 967 Slavković R., 517, 651 Slavković V., 517 Smiljanić P., 299 Sofla A., 751 Stamenković D., 365, 473 Stamenković M., 983 Stanković B., 895 Stanković G., 821 Stanojević A., 889 Stanojević-Baltić M., 249 Stefanović V., 377, 735 Stepanić V., 803, 873 Stepanović Ž., 497 Stevanović Hedrih K., 43 Stojanović Slavoljub 129 Stojanović Sreten 585 Stojković S., 291 Stošić S., 311 Stupar S., 117, 249, 341, 359, 419 Svorcan J., 249 Šalinić S., 177 Škorić B., 485 Šumarac D., 317, 705 Todić M., 699 Todić N., 243, 651, 843 Todorović K., 657, 669 Tomašević M., 757 Tomić N., 781 Topalović M., 371, 401 Trišović N., 1005 Trivković S., 341 Trouillas P., 867 Turnić D., 437, 741

Ugrčić M., 939 Vasić Z., 365, 735 Vasin S., 461 Vasko M., 547 Vasović I., 335, 377, 485 Vasović N., 657, 669 Vavva M., 815 Velicki L., 781 Velimirović K., 621 Velimirović N., 621 Veljić V., 591, 961 Veljović Lj., 199, 523, 921, 927, 933 Vidaković J., 627, 681 Vidanović N., 467 Vignal P., 71 Vitić A., 237 Vujičić V., 153 Vujović S., 231 Vukčević M., 989 Vukičević A., 825 Vukojević N., 383 Vukojević V., 889 Vuković Đ., 237 Vuković J., 25 Vuković N., 165, 675 Vuksanović Đ., 443 Vulović S., 497 Zdraković N., 809 Ziemys A., 787 Zindović B., 225 Zorić N., 117, 419 Zuković M., 211 Živanić D., 663 Živanović Marko, 763 Živanović Miloš, 111, 217 Živković J., 497 Živković Milorad, 821 Živković Miroslav, 243, 401, 491, 497, 503, 509, 517, 729, 821

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Fourth Serbian (29th Yu) Congress on Theoretical and Applied Mechanics Vrnjačka Banja, Serbia, 4-7 June 2013 M1-13

ROLE OF OSCILLATORY SHEAR INDEX IN PREDICTING THE OCCURRENCE AND DEVELOPMENT OF PLAQUE

Milan Blagojević1, Aleksandar Nikolić1, Miroslav Živković1, Milorad Živković2, Goran Stanković

2

1

University of Kragujevac, Sestre Janjić 6, 34000 Kragujevac, Serbia Faculty of Engineering,

e-mail: [email protected], [email protected], [email protected] 2

Belgrade University, Belgrade, dr Subotića 8, 11000 Belgrade, Serbia School of Medicine,

e-mail: [email protected], [email protected]

Abstract. The paper presents theoretical basis and results obtained by calculation of blood flow in carotid artery bifurcation, whereby the emphasis is placed on the plaque occurrence analysis based on oscillatory shear index (OSI). OSI is the temporal fluctuation of low and high average shear stress. The endothelial shear stress is a major factor that affects the formation of plaque phenomenon. There is a complex hemodynamic conditions in these areas where local fluid flow dictates the occurrence and development of plaque. Favorable conditions for the plaque development occurring in areas characterized by low shear stress, while areas with higher values of OSI index are not susceptible. Arterial bifurcations are the places in vascular tree where atherosclerosis mainly occurs. OSI index response to the appearance of plaques in the common carotid artery and branches (CCA, ECA and ICA) are considered on three out of eight possible combinations of plaque locations. Algorithm for the calculation of OSI index are embedded in software PAK-F and the results are written in FEMAP neutral and Paraview VTK file format.

1. Introduction The relationship between flow in the arteries, the wall shear stress distribution and the sites where diseases can develop has motivated much of a research on arterial flow in the last decade. Wall shear stress (WSS) is the main flow-related factor affecting the distribution of atherosclerosis. It is now accepted that the sites where shear stresses are extreme or change rapidly in time or space are critical in developing diseases [1,2]. Atherosclerosis occurs predominantly at branching locations of the vascular tree, where the arteries have relatively complex geometry that results in a disturbed behavior of a blood flow [3]. There is a need to identify, in vivo, early plaques that are likely to develop characteristics of either vulnerable plaque or lumen obstruction. Then selective interventions could be applied to these areas in order to avoid subsequent cardiac events [4]. Non-invasive diagnostic procedures such as MRI are often used in this context, but do not provide information on time-dependent pressures and wall shear stresses - key quantities considered to be partially responsible for the formation and development of related pathologies. Numerical methods, such as finite element analysis (FEA), allow sufficiently accurate determination of transient fields of pressures and wall shear stresses. Finite element models

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allow one to simulate experimental changes caused by variations of some parameters, and analyze the effects and influences of a single component within the phenomenon investigated [5,6].

2. Oscillatory shear index (OSI) Temporal oscillations of low and high average shear stress are measured across oscillatory shear index (OSI). Shear vector can be calculated from the stress tensor σ and the normal vector to the surface n :

tσ n= ⋅ . (1)

Surface shear vector st is defined as the tangential component of the shear stress:

( )s = − ⋅t t t n n . (2)

The scalar value of the mean shear stress meanτ is defined as the average intensity values of the shear vector:

0

1T

mean sdtT

τ = ∫ t . (3)

while the scalar magτ is defined as the average value of the intensity of the shear vector:

0

1T

mag s dtT

τ = ∫ t . (4)

Oscillatory shear index (OSI) is defined by the expression:

1 12

mean

magOSI

ττ

= −

. (5)

In case when mean magτ τ= , their ratio is 1mean

mag

ττ

= , and 0OSI = . On the other hand, when

0meanτ = , ratio is 0mean

mag

ττ

= , and 12

OSI = . The value of OSI varies in the

interval [ ]0,0.5 .

3. Generation of Finite Element Models This problem is observed on 2D examples in the literature [7]. In this paper we observe the following cases of coronary artery bifurcation: (a) with no stenosis, (b) stenosis of the side branch, and (c) stenosis in all branches (Fig. 1). In addition, we observed coronary bifurcation model generated based on MSCT scan of patient. CAD model of coronary bifurcation is generated in CATIA software (Fig. 1). Finite element models were generated using in-house software STL2FEM [8], thus the

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preparation of model also been made in software GOM Inspect (polygonization, setting borders of model). Software STL2FEM, based on multiblock approach, is very suitable when dealing with irregular geometries, especially hexahedral elements meshing of the irregular anatomical structures (Fig. 1). Finite element simulations of coronary flow are performed using software PAK-F [9]. Blood is approximated as an incompressible Newtonian fluid with a density of 1050 kg/m3 and a dynamic viscosity of 0.003675 Pas [9]. One cardiac cycle (0.89 s) is simulated in 20 steps with time step size of 44.49 ms. Maximal diastolic flow velocity in the inlet is 33 cm/s.

Velocity profile used for simulating is pulsatile flow. Velocities of nodes on the arterial wall are equal to zero. We calculate ESS, OSI index, velocity, and pressure throughout cardiac cycle.

(a) (b) (c)

(d) (e) (f)

Figure 1. CAD and FE models of coronary artery bifurcation: (a, d) model with no stenosis, (b, e) model with stenosis on side branch, (c, f) model with stenosis on all branches.

4. Results and Discussion Analyses by 3D models that consider only the ideal geometry of arterial bifurcations are not suitable to draw conclusions that will come to develop the disease (Fig. 2). In cases where the pathology is modeled, one can predict how it will thrive. This adds to the importance of efforts to generate high-quality patient-specific models, and software STL2FEM contributes to these efforts. On example of real coronary bifurcation it is clearly visible areas where change in the direction of shear stress is negligible, so that the oscillatory shear index, with the field endothelial shear stress, modeling the distribution of LDL and other tools and techniques can be used to predict the occurrence and development of pathology (Fig. 3).

(a) (b) (c)

Figure 2. Oscillatory Shear Index (OSI) for observed geometrically ideal cases.

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Figure 3. Oscillatory Shear Index (OSI) for observed patient-specific case.

5. Conclusion A very short time required to generate the model allows the treatment of large number of patients. This model offers the possibility for monitoring patients over time, which can become a part of their medical records. Thanks to rapid modeling, this methodology not only allows detailed characterization of arterial plaque at a given moment in time but, applied routinely, can give an insight how the plaques change over time and what antecedent features predict their future behavior.

Acknowledgement. Part of this research has been supported by Ministry of Education, Science and Technological Development, Republic of Serbia, Grants TR32036 and OI175082.

References

[1] Giannoglou G, Antoniadis A, Koskinas K, Chatziziz Y. (2010) Flow and atherosclerosis in coronary bifurcations, EuroIntervention, 6, pp. J:J16-J23.

[2] Chatzizis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH (2007) Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodelling; molecular, cellular, and vascular behavior, Journal of the American College of Cardiology, 49, pp. 2379-2393.

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