Professor R.T. PARDASANI Dean, School of Chemical Sciences and Pharmacy, Professor & Head, Department of Chemistry, Central University of Rajasthan, Bandarsindri, Distt. Ajmer-305801

Phone +91-1463-238535 (O) +91-9414320581 (Mob) e-mail : rtpardasani@curaj.ac.in

Research Specialization (Major Scientific fields of interest)

• Synthetic Organic and Heterocyclic Chemistry • Organic Photochemistry • Boron Chemistry • Computational Chemistry and Molecular Modelling

Educational Qualifications

B.Sc. University of Rajasthan 1973 I Class, Silver Medal for 3rd position

M.Sc. University of Rajasthan 1975 I Class, Gold Medal for 1st position

Ph.D University of Rajasthan 1979 Natural Products Chemistry

Ph.D University of Manchester 1982 Synthetic Organic Chemistry

Teaching Experience

Under Graduate : 29 Years Post Graduate : 29 Years

Research Experience Total research experience : 33 Years Courses being taught : Spectroscopy : Heterocyclic Chemistry : Research Methodology : Organic Chemistry Labs for MSc I, II & III Semesters

Number of Ph.D. students

17 students awarded Ph.D. degree 03 students currently registered/working for Ph.D. degree Postdoctoral Experience

• Research Associate, Department of Chemistry, The University of Manchester, Manchester, 1979-1982.

• Post-Doctoral Research Fellow, University College of Swansea, United

Kingdom, 1984-1986.

• Post-Doctoral Research Officer, University of Wales, Swansea, United Kingdom, September 2005-August 2006.

Selected Publications of Prof. R.T.Pardasani

1. “Transformation of benzo[b]thiophene-2,3 diones to functionalized diaryldisulfides”, Ramchand T. Pardasani, Saurabh Singh, Johnson George, Rahul Joshi and T. V. Sunder, Lett. Org. Chem., 10(5), 2013, 358.

2. “A versatile route to benzodiazocine and spiropyran derivatives through chalcones”, Johnson George, Saurabh Singh, Rahul Joshi, Ramchand T. Pardasani, J. Chem.

Sci.,125(3), 2013, 517.

3. “Synthetic and Theoretical Approach towards Spirothiazolidinone Systems”, Johnson George, Saurabh Singh, Rahul Joshi, R. T. Pardasani, Heterocycles, 87, 2013, 591.

4. “Novel tin complexes containing oxime ligand: Synthesis, characterization and computational investigation” Raji Thomas, Nelson Joseph P, R. T. Pardasani, P. Pardasani and T. Mukherjee. Helvetica Chimica Acta, in Press 2013.

5. “Photoinduced [4+2] cycloaddition reactions of benzo[b] thiophene-2,3-diones with alkenes” Sonali Verma, Barkha Srivastava, Kusum Sharma, Rahul Joshi, Pushpa Pardasani and R.T. Pardasani, Res. Chem. Intermed ., 38, 2012, 723.

6. “[3+2] Cycloaddition reactions of thioisatin with thiazolidine-2-carboxylic acid: a versatile tool to new heterocyclic scaffolds”, Sonali Verma, Johnson George, Saurabh Singh, Pushpa Pardasani and Ramchand T. Pardasani, Org. Med. Chem. Lett., 1, 2011, 6.

7. “New polymeric sulfide borane complexes: Convenient hydroborating and reducing agents”, Keith Smith, Asim A. Balakit, Ramchand T. Pardasani and Gamal A. El-Hiti, J. Sulfur Chem., 32, 2011, 287.

8. “Recent Advances in Benzoquinone Chemistry”, Ignatious Abraham, R. Joshi, Pushpa Pardasani and R. T. Pardasani, J. Braz. Chem. Soc., The Brazilian Chemical Society, 22, 385, 2011.

9. “A DFT And CASSCF Study of Photocycloaddition Reactions of Biradicals From 6-

Amino-2-(3’-Thienoyl)-1,4-Benzoquinone”, G.Sharma, I. Abraham, P.V.Bharatam, R. T. Pardasani and T.Mukherjee, Bull. Chem. Soc. Jpn., The Chemical Society of Japan, 12, 1477, 2009.

10. “Stereoselective Synthesis and Antioxidant Activity of Azabicycloadducts Derived from 9,10-Phenanthrenequinone”, Komal Arora, Densely Jose, Dharmendra Singh, Anshu Gumber, R.S. Gupta, Pushpa Pardasani and R.T. Pardasani, Heteroatom Chem., Wiley, 20, 379, 2009.

11. “A DFT study on regioselectivity in [2+2] photocycloaddition of 6-amino-2-3(3’-thienoyl)-1,4-benzoquinone with ethylene”, G. Sharma, Ignatious Abraham, M.K.

Pathak, R. T. Pardasani and T.Mukherjee, Res. Chem. Intermed., Springer, 35, 219, 2009.

12. “Synthesis,Semiemperical Stereoselectivity and Pharmacological Activity of a New Class of Spiro Pyrrolidine and Isoquinoline Derivatives”, A.V. Londhe, B.Gupta, S.Kohli, P.Pardasani and R.T. Pardasani, Z. Naturforsch. B, VZN, 61b, 213, 2006.

13. “N-Ethyl-1'-5-dehydro-1'-[2-thioxo-4-hiazolidinone]-acenaphthylene-2'-one”, R.T. Pardasani, Abhinandan Jain, T.V. Sundar, V. Parthasarathi, and S. García-Granda, Acta. Cryst., Wiley-Blackwell, E59, 1967, 2003.

14. “Theoretical Studies on the Stereochemical Course of 1,3-Dipolar Cycloaddition of Azomethine Ylides Derived from Indol –2,3-dione and Thiazolidine-4-carboxylic acid”, R.T. Pardasani, P. Pardasani, S.K. Yadav and P.V. Bhartam, J. Heterocycl.

Chem., Wiley, 40, 557, 2003.

15. “rac-2S,3R,5S]-spiro-{3-methoxycarbonyl-1-aza-bicyclo[3.3.0]octane-2,1'-acenaphth-ylene}-2'-one”, R.C. Mehrotra, R.T. Pardasani, I. Sharma, T.V. Sundar, V. Parthasarathi, C. Álvarez-Rúa and S. García-Granda, Acta. Cryst., Wiley-Blackwell, E59, 280, 2003.

16. “Theoretical and synthetic approach to novel spiroheterocycles derived from isatin

and L-proline via 1,3-dipolar cycloaddition reaction”, R. T. Pardasani, P. Pardasani, V. Chaturvedi, S.K. Yadav, A. Saxena and I. Sharma, Heteroatom Chem., Wiley, 14, 36, 2003.

17. “Stereoselective synthesis of Substituted Thiazolidine Derivatives” R. T. Pardasani, P. Pardasani, D. Sherry and V. Chaturvedi, Synth. Commun., Thieme, 32, 435, 2002.

18. “(rac-5 RS,7 RS,8S R)-Spiro[7-methoxycarbonyl-1-aza-3-thia bicyclo [3.3.0]-

octane-8,1-acenaphthylen]-2-one”, R. T. Pardasani, P.Pardasani, A. Saxena, T.V. Sundar, V. Parthasarathi, C. Álvarez-Rúa and S. García-Granda, Acta. Cryst., E 58, 1405, 2002.

19. “One Electron Reduction Studies on Some Aroyl/ Hetroacyl-1,4-Benzoquinones (RCO-BQ)”, R. T. Pardasani, P. Pardasani, S. Muktawat, R. Ghosh, M.C. Rath and T. Mukherjee, , Res. Chem. Intermed., Springer, 27, 379, 2001.

20. “Synthesis and Antibacterial Activity of Some Fused and Spiro Imidazolidine Derivatives”, R.T. Pardasani, P. Pardasani, D. Sherry, V. Chaturvedi and A. Saxena, Indian J. Heterocyclic Chem., 10, 129, 2000.

21. “Photochemistry of Boron Compounds”, A. Pelter, R.T. Pardasani and P. Pardasani, Tetrahedron, Pergamon, 38, 7339, 2000.

22. “Synthetic and Spectral Studies of Novel Spiro [Indole-3,′-Pyrrolo (1,2-c) Thiazoline]-2-one via Indol-2,3-dione”, R. T. Pardasani, P. Pardasani, R. Ghosh, D. Sherry and T. Mukherjee, , Heteroatom Chem., Wiley, 10, 381, 1999.

23. “Thermal and Photochemical Reaction of Isoxazolone with Indol-2,3-dione Derivatives”, R. T. Pardasani, P. Pardasani, S. Muktawat, R. Ghosh and T. Mukherjee, J. Heterocyclic Chem., Wiley, 36, 189, 1999.

24. “Photocyclisation of Aroyl-1,4-quinones as Precursors for Anthracyclinones and Heteroanthracyclinones”, R.T. Pardasani, P. Pardasani, S. Muktawat, R. Ghosh and T. Mukherjee, Res. Chem. Intermed., Springer, 24, 973, 1998.

25. “Synthesis of Anthracyclinones intermediates: Diels-Alder Reaction and [1,5] rearrangements of some benzoyl-1,4-benzoquinones”, R. T. Pardasani, P. Singh A. Prashant, C.P. Pokharna and B. Chaudhary, De Pharmazie, Govi-Verlag, 48, 943, 1993.

26. “Synthesis of some Benzoy-1,4-benzoquinones as precursors for Anthracyclinones”, R.T. Pardasani, P. Singh A. Prashant, C.P. Pokharna and B. Chaudhary, De

Pharmazie, Govi-Verlag, 48, 699, 1993.

27. “Hindered Organoboron Groups in Organic Chemistry, 19. Synthesis of Heteroatom Substituted Dimesitylborylmethanes”, A. Pelter, R.T. Pardasani, J.W. Wilson, M.V. Garad, Tetrahedron, Elsevier, 49, 2979, 1993.

28. “Conversion of Lapachol to Rhinacanthin-A and Other Cyclised Products”, R.T. Pardasani, P. Singh, A. Suri and C.P. Pokharna, Z. Naturforschung, The Zeitschrift für Naturforschung, 47b, 1031, 1992.

29. “Thermal and Photochemical Investigation of the Reaction of Indol-2,3- dione with Pyrazolone”, R.T. Pardasani, K.C. Joshi, A. Dandia and S. Bhagat, Heterocycles, Elsevier, 32, 1491, 1991.

30. “Studies of the synthesis of Xanthones, Part V Synthesis of Bromoxanthones”, R.T. Pardasani, K.N. Trivedi, R.S. Verma and G.M. Patel, Pol. J. Chem., The Polish Chemical Society, 62, 409, 1988.

31. “The Dimesitylboron Group in Organic Synthesis, IX. A most unusual Reaction of

Electrophilic Attack on Sulfur in α-Thiocarbanion”, A. Pelter, R.T. Pardasani, G. Bugden and J. Wilson, Tet. Lett., Pergamon, 27, 5033, 1986.

32. “Photochemistry of Benzoyl-1,4-benzoquinones”, R.T. Pardasani, and J. M. Bruce, J. Photochem., 17, 106, 1981.

33. “Benzoquinones and related compounds, Part 3, Preparation of 1,4-Benzoquinones by oxidation of Hydroquinones with Manganese dioxide”, R.T. Pardasani, J.M. Bruce and S. Fitzjohn, J. Chem. Research (S), Royal Society of Chemistry, 252, 1981.

34. “Base-induced benzoyl Benzoyl Migration in Diels-Alder Adducts of Benzoyl-1,4- benzoquinones”, R.T. Pardasani, J.M. Bruce, I. Watt and S. Fitzjohn, J. C. S. Chem.

Commun., Royal Society of Chemistry, 171, 1981.

35. “Quinones and constituents from the Haplophragma adenophyllum”, R.T. Pardasani, K.C. Joshi, P. Singh and G. Singh, Planta Medica, Thieme, 37, 60, 1979.

36. “Gmelofuran – An unusual sesquiterpene”, R.T. Pardasani, K.C. Joshi, P. Singh, A. Pelter, R.S. Ward and R. Reinhardt, Tet. Lett., Pergamon, 4719, 1978.

37. “Chemical constituents of the stem heartwood of Markhamia stipulate”, R.T. Pardasani, K.C. Joshi and P. Singh, Planta Medica, Thieme, 34, 219, 1978.

38. “Chemical components of the roots of Tectona graudia and Gmelana arborea”, R.T. Pardasani, K.C. Joshi and P. Singh, Planta Medica, Thieme, 32, 71, 1977.

39. “Quinones and constituents from the roots of Tecomella undulate”, R.T. Pardasani, K.C. Joshi and P. Singh, Planta Medica, Thieme, 31, 14, 1977.

Selected Scientific Presentations of Prof. R.T. Pardasani

1. “Thioisatin- A molecule for heterocyclic integriety”, 100th Indian Science Congress,

University of Calcutta, Kolkata, 3-7 Jan 2013, Oral presentation O-08.

2. “Photocycloaddition reactions of 1, 2 and 1,4-diones”, 11th Biennial Trombay

Symposium on Radiation & Photochemistry (TSRP-2012), BARC, Mumbai, 4-7 January 2012, Abstract PC-48, Page-279.

3. Invited Lecture on “Photocycloaddition reactions of 1,4-benzoquinones and α-diones”, National Symposium on Radiation & Photochemistry (NSRP-2011), JNV University, Jodhpur, March 10-12, 2011; IT-05.

4. “Photocycloadditions and Pulse Radiolytic Investigation of some 1,4-Benzoquinones”, National Symposium on Organic Synthesis, IIS University, Jaipur, 18-19 February 2011, Abstract No. 5, Page 46.

5. Invited Lecture on “Cycloaddition Reactions of 1,4-Benzoquinones And α-Diones”, 12th International Conference on Emerging Interfaces of Physical Sciences (CONIAPS XII), University of Rajasthan, Jaipur, December 22-24, 2010, Abstract C-029, Page – 200.

6. “Theoretical Studies on [2+2] Vs [3+2]-Photocycloadditions of 6-Amino-2-(3-Thienoyl)-1,4-Benzoquinone)”, 98th Indian Science Congress, SRM University, Chennai, 3-7 January, 2011; Section of Chemical Sciences, Abstract no.31, Page-21.

7. “[2+2] vs [3+2] Photocycloadditions of 6-amino-2-(3-thienoyl)-1,4-benzoquinone: A DFT Study” (with I. Abraham and T. Mukherjee), 3rd Asia Pacific Symposium on

Radiation Chemistry (APSRC-2010) and DAE BRNS 10th Biennial Trombay Symposium

on Radiation & Photochemistry (TSRP-2010), Lonavala, India, September 14-17, 2010; Abstract PC-034, Page-231.

8. “Quinoxaline Quinones: Synthesis and Theoretical Approach towards the Regioselectivity in Diels-Alder Cycloadditions” 97th Indian Science Congress,

University of Kerala, Thiruvananthapuram, 3-7 January, 2010; Section IV: Chemical Sciences, Abstract no.33, Page-84.

9. “In Silico Elucidation of Photocycloadditions and Pulse Radiolytic Investigations on Some 1,4-Benzoquinones” (With I Abraham), 97th Indian Science Congress, University of Kerala, Thiruvananthapuram, 3-7 January, 2010; Section IV: Chemical Sciences, Abstract no.29, Page-81.

10. Invited Talk on “Photocycloaddition and Pulse Radiolytic Studies on some Hetero-1,4-benzoquinones” 22nd International Congress on Heterocyclic Chemistry (ICHC-2009), Memorial University, St. John’s, Canada; 2-7 August, 2009; Books of Abstracts, OL-20, Page-102.

11. Photochemical and Pulse Radiolytic Studies on some Hetero-1,4-Benzoquinones

(with I. Abraham and P.K. Khatri), National Symposium on radiation and

Photochemistry (NSRP – 2009); Kumaun University; Nainital; 12-14 March, 2009; Proceedings of NSRP-2009, Abstract RC-35.

12. Synthetic, Photochemical and Pulse Radiolytic Study of Hetero-1,4-Benzoquinones (with I. Abraham), 96th Indian Science Congress, North Eastern Hill University Shillong, 3-7 January, 2009; Section IV: Chemical Sciences, Abstract No. 71, Page – 49.

13. An Efficient Approach to the Synthsis of New Spiropyrrolidines via 1,3 Dipolar Cycloaddition Reactions (with Sonali Verma and P. Pardasani), 96th Indian Science Congress, North Eastern Hill University Shillong, 3-7 January, 2009; Section IV: Chemical Sciences, Abstract No. 150, Page – 107.

14. Photocycloaddition Reactions of Hetero-1,4-quinones : An Approach to the Synthesis of Quinone based Natural Products, 95th Indian Science Congress, Andhra

University, Visakhapatnam, January 3-7, 2008.

15. Synthesis and Conformational Control in Photocycloaddition Reactions of Hetero-

1,4-benzoquinones (with Gitanjali Sharma and T. Mukherjee), National Symposium on

Radiation and Photochemistry-2007, University of Madras, Chennai, January 29-31, 2007. PC-43.

16. Photocycloaddition Reactions of Heterocyclic 1,4-benzoquinones: A synthetic and Theoretical study (with G.Sharma, I.Abraham, P.V.Bharatam and T.Mukherjee), 2nd Int. Conf. on Heterocyclic Chemistry, Department of Chemistry, University of Rajasthan, Jaipur, India, Dec. 16-19, 2006, PS-163.

17. Conformational Study of [3+2]/[2+2] Photochemical Cycloaddition Reactions of Heteroacyl-1,4-benzoquinones (with Gitanjali Sharma, Pushpa Pardasani, P. V. Bharatam and T. Mukherjee), Trombay Symposium on Radiation and Photochemistry

(TSRP-2006), Bhaba Atomic Research Centre, Mumbai-400 085, India. January 5-9, 2006, Vol II. PC-101, PP-295.

18. Synthesis and [3+2] Photochemical Cycloaddition Reactions of Heteroacyl-1,4-benzoquinones (with Ignatious Abraham, Pushpa Pardasani and T. Mukherjee), Trombay Symposium on Radiation and Photochemistry (TSRP-2006), Bhaba Atomic Research Centre, Mumbai-400 085, India. Jan 5-9, 2006, Vol.II PC- 97, PP-291.

19. Synthesis and [2+2] Photochemical Cycloaddition Reactions of Heteroacyl-1,4- benzoquinones (with Praveen K. Khatri, Pushpa Pardasani and T. Mukherjee) Trombay Symposium on Radiation and Photochemistry (TSRP-2006), Bhaba Atomic Research Centre, Mumbai-400 085, India. Jan 5-9, 2006, Vol. II, PC-98, PP-292.

20. Synthesis and Theoretical Studies on [2+2]/ [3+2] Photocycloaddition in Heteroacetyl-1,4-Quinones, (with Gitanjali Sharma and Swati Kohli), National

Symposium on Radiation and Photochemistry - 2005, , University of Karnataka, Dharwad., January 17-19, 2005, Abstract PC-12.

21. Theoretical Studies on the Stereochemical Course of [3+2] Cycloaddition Reactions

via Azomethine Ylides (with Swati Kohli), Recent Advances in Chemical Research, Department of Chemistry, University of Rajasthan, Jaipur, March 28-29, 2005, Abstract P-103.

22. Mechanistic aspects of [2+2] and [3+2] photo- cycloaddition of 1,4-quinones : A theoretical study (with S.K. Yadav, P. Raisinghani, P. Pardasani, and T. Mukherjee), International Trombay Symposium on Radiation and Photochemistry (TSRP-2004),

BARC, Mumbai, January 8 – 12, 2004, Abstracts Vol. II, PC 30, PP.59.

23. Theoretical Studies on the Stereochemical Course of [3+2] Cycloaddition Reactions via Azomethine Ylides (with Swati Kohli), International Conference on Chemistry Biology Interface : Synergistic New Frontiers (CBISNF-2004), Vigyan Bhawan, New Delhi, November 21-24, 2004, Abstract P-23.

24. One-electron reduction studies of some aroyl/heteroacyl-1,4-benzoquinones (with

S.K. Jain, S.K. Yadav and T. Mukherjee), Organic Free Radicals-EUCHEM, University of York, UK, 21-25 July, 2002.

25. A Comprehensive Approach to the Photosynthesis of Bioactive Compounds by the Reaction of Oxazolidine, Thiazolidine and Imidazolidine Derivatives with Indol-2,3-diones (with P. Pardasani, C. K. Ojha, A. Saxena, I. Sharma and T. Mukherjee), Third Asian Photochemistry Conference (APC-2002), Organised by BRNS & BARC, Hotel Centaur, Mumbai, Jan. 6-11, 2002, PP-81, Abstract Page 189.

26. 15. Theoretical Studies of 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylide with Ethene and Ethyne (with S. K. Yadav and I. Sharma), Int. Conf. on Heterocyclic Chemistry, Department of Chemistry, University of Rajasthan, Jaipur, India, Dec. 15-18, 2001, PS-95.

27. Photosynthetic Routes to Novel Heterocycles (With Densely Sherry), Trombay

Symposium on Radiation and Photochemistry (TSRP-2000), BARC Mumbai. January

2000.

28. Photolysis and Pulse Radiolysis of Benzoyl and Heteroacyl-1,4-quinones, XIX International Conference of Photochemistry, Duke University, NC, USA, 1-6

August 1999 , 1999, PS-129

29. Photosynthetic Routes to Novel Spiro Compounds, International Trombay (with S.Mukhtawat and R.Ghosh), Symposium on Radiation and Photochemistry (TSRP-

98), BARC, Mumbai, 1998, Abstract p- 84

30. Experimental and Theoretical Aspects of Regiospecific Cycloadditions using Heterobenzo-quinones, Indo-German Symposium on Organic Synthesis, Hyderabad, 1996, p 77.

31. Approaches towards C-ring of Anthracyclinones and Heteroanthracyclinones : A novel photocyclisation of Benzoyl-1,4-benzoquinones ( with S.Mukhtawat), International Trombay Symposium on Radiation and Photochemistry TSRP 96), BARC,

Mumbai, 1996, Abstract p- 260.

32. Synthetic Approaches Directed towards Heteroanthracyclinones, 10th International Conference on Organic Synthesis, Bangalore, India, Abstract No.-P-WED-060, 1994.

Books – International Publisher

1. Magnetic Susceptibility of Paramagnetic Compounds, Landolt Bornstein, (with P.

Pardasani), Vol II/31B-F, Springer-Verlag, Germany, in Press, 2013.

2. Magnetic Susceptibility of Paramagnetic Compounds, Landolt Bornstein, (with P.

Pardasani), Vol II/31A, Springer-Verlag, Germany, February 2012 (A volume of

662 pages).

3. Boron-11 NMR Data, Landolt Bornstein, (with P. Pardasani), Vol III/40,

Supplement to Vol III/35, Springer-Verlag, Germany, 2009 (A volume of 569

pages).

Book Chapter

Boron-11 NMR Data, Landolt Bornstein, (with A. Pelter and P. Pardasani), Vol.

III/3A, Chapter 2, p 7-130, Springer-Verlag, Germany, 1997.

Membership of Professional Bodies

• Member, International Society of Heterocyclic Chemistry

• Life Member, Indian Science Congress, Kolkata

• Life Member, Indian Chemical Society, Kolkata

• Life Member, Indian Society for Radiation and Photochemical Sciences,

Mumbai.

• Life Member, Chemical Research Society of India, Bangalore

Awards and Scholarships

• Visiting Scientist, University of Wales Swansea, UK, 2002, 2004, 2005. • Royal Society London Visiting Fellow, University of Wales Swansea, UK,

1999.

• Dr. Ghanshyam Srivastava Memorial Award, Indian Chemical Society, Coimbatore, 1995-1996.

• INSA Visiting Fellow, Central University of Hyderabad, 1994-1995.

• Need-cum-Merit Scholarship, Govt. of Rajasthan, 1970-75.

RESEARCH HANDRESEARCH HANDRESEARCH HANDRESEARCH HAND----OUTSOUTSOUTSOUTS

One-pot Multicomponent Synthesis of Novel Heterocyclic Frameworks

Lett. Org. Chem., 10(5), 2013, 358 J. Chem. Sci.,125(3), 2013, 517. Heterocycles, 87, 2013, 591 Org. Med. Chem. Lett., 1, 2011, 6 Heteroatom Chem., Wiley, 20, 379, 2009 Res. Chem. Intermed ., 38, 2012, 723 Indian J. Heterocyclic Chem.¸ 15, 137, 2005

S

O

CH3

O

N

H3CH2C

H3CH2C

S

O

H3C

O

N

CH2CH3

CH2CH3

S

O

OPh

Ph

R

S

O

O

R

Et 2NHCOCH3

S

NS

O

O

H2N

S

O

ORR H

Ph

Ph

H

SHCH2COOH

NH

HNO

NH

S

O

O

C6H5

H

H

H

EtOH R

NH

HCOOH

NH

O

H3CNH

HNO

NH

S

N

H

R

Ph-C=C-H CH2=CHCOOMe

S

N

Ph

H H

S

N

MeOOC

H

R R

CH

3 CN,-C

O2, -H

2 O

Et2NH, CH3COOH,HCl

trans-stilbene

[4+2] / hυ

2-Acetyl pyridine

1

2

34

5

6

7

8ref lux, 7h

81%

O

O O

hv

Cycloaddition Reactions and Pulse Radiolytic Characteristics of Radicals from 1,4-Benzoquinones

250 300 350 400 450 500 550 600 650 700

-0.01

0.00

0.01

0.02

0.03

0.04

Isopropanol

MS pH 2.9

MS pH 7.0

∆ Absorbance

Wavelength, nm

J. Chem. Research(S), 1981, 252; Indian J. Chem., 1992, 31B, 267; Heterocycl. Commun., 2006, 12, 463; Indian J. Chem., 2009, 48B, 1590. Bull. Chem. Soc. Jpn., 2009, 82, 1477; Res. Chem. Intermed., 2009, 35, 219; J.Braz.Chem.Soc., 2011, 22, 385

OCH3

OCH3

X

OCH3

OCH3

XAr

O O

O

XAr

O

Ar-COOH PPA

70oC

+CAN/ CH3CN

RT/6h

O

O

From Nature

By Synthetic Strategies

Cycloaddition Reactions

Photocyclisation

Pulse Radiolytic Study1,4-Benzoquinone

Bulky Organoboranes in Organic Synthesis

Stannyl and Germanyl Substituted Organoboranes

X-ray Crystal Structure of Mes2BCH2GePh3

X-ray Crystal Structure of (Mes2BCH2)2GeEt2

X-ray Crystal Structure of (Mes2BCH2)2 SnMe2

Tetrahedron Lett. 1986 , 27, 5033 Tetrahedron, 1993, 49, 2979 J. Indian Chem. Soc., 1997, 74, 433, Tetrahedron, 2000, 38, 7339-7369

CH3-BR

RCH2-B

R

RLi

+

CH3-BR

R

base

Li+

BuLi

BuLi

R = H, ate complex

R = bulky group

Computational Chemistry and Molecular Modeling of Heteocycles

NPA and MESP plot for Thioisatins

HOMO

LUMO

HOMO and LUMO plots for benzodiazocines Intramolecular interactions of spirothiazolidinones

J. Chem. Sci.,125(3), 2013, 517. Heterocycles, 87, 2013, 591

0.295

0.325

-0.464

-0.471

0.480-0.187

-0.152-0.247

-0.183

-0.246-0.156

-0.258

-0.248

-0.247

-0.253

NPA analysis; Atoms are coloured by their

NPA charge

0.481

-0.473

0.324

-0.466

0.294

-0.159

-0.181

-0.241

0.252

0.243

-0.181

-0.042

-0.691

0.240

0.249

0.249-0.152

0.254

NPA analysis; Atoms are coloured by their

NPA charge