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  • 8/22/2019 Profile: Professor Michael Marmot

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    HEALTH SCIENCE

    NOV 2010 SAM

    BEST

    ANDFAIREST

    Professor Sir Michael Marmot,

    the recently appointed

    President of the British

    Medical Association, is

    a world-leading socialepidemiologist who says he was greatly

    influenced by his undergraduate education

    at the University of Sydney.

    Though he didnt set out to change

    the world, Marmot has certainly had

    a huge impact on its health; hes just

    completed a groundbreaking review

    of health inequalities in Britain, after

    chairing the 2008 WHO Commission into

    social determinants of health. Marmot

    is presently also the Director of the

    International Institute for Society and

    Health and a Medical Research Council

    Research Professor of Epidemiologyand Public Health at University College

    London.

    And while he may have taken on

    Britains centuries-old class structures

    in his quest to overturn the social

    determinants of health, Marmots

    reputation and experience stood him

    in good stead, with few questioning his

    sometimes startling findings. In his review

    of public health in Britain, Marmot pointed

    out that while a man from the wealthiest

    London borough of Kensington and

    Chelsea had a life expectancy of 88 years,

    just 16 kms away in Tottenham Green,

    male life expectancy was 71 years.Marmot, now 65, has three adult

    children and has lived in London for

    many years, leaving Australia to complete

    his PhD at the University of California,

    Berkeley in 1972. Born in North London,

    Marmot moved with his family to Sydney

    at the age of four. His parents were poor

    immigrants who had both left school at a

    young age, and he says that when he grew

    up, great value was placed on education.

    On leaving Sydney Boys High School,

    he went straight into an undergraduate

    medical degree, but after four years of

    medical studies, he took the opportunityto spend a year doing an intercalated BSc

    in pharmacology. I spent a year in the lab,

    which was wonderful.

    During that year, he had time to do

    his own research but also met people

    outside medicine, attended lectures in

    English literature and befriended students

    of sociology and political science. I

    suddenly discovered the University, he

    says. Until then, I had been a medical

    student but that year, I became auniversity student.

    Marmots exposure to literature andpolitics at such a seminal time clearly

    influenced his career path. Beinginterested in social determinants of healthand inequalities in health means you need

    to draw on a wide array of influences andknowledge and understanding, he says.

    He followed that year with a juniorresidency at Royal Prince Alfred Hospitalin Sydney when, despite working around

    100 hours a week, he completed first-yearEnglish Literature. The following year, hewas oered a year in thoracic medicine,combining clinical work with some

    research interest. But thoracic medicinewasnt the path he wanted to follow.

    Without quite knowing what it was Iwanted to do, I was concerned about why

    people got ill in the first place and how it

    related to the circumstances in which theylived and worked. I hadnt articulated itvery well, but that was certainly where my

    interests were heading.As a young intern, Marmot had noticed

    that Greek and Italian immigrants livingnear the hospital, struggling to integrate

    into the community partly due to languagebarriers, would present with a variety ofproblems that he started to think were thephysical manifestations of some of the

    problems in their lives. He approachedsociologist-turned-epidemiologist LeonardSyme with his ideas, leaving Australia in

    1971 for UC Berkeley, under Syme, wherehe looked at rates of heart disease in menof Japanese ancestry living in Japan,Hawaii and California.

    Japanese culture was cohesive and

    gave protection against the stresses ofdaily life, but as the Japanese becamemore westernised in California, they lostthose protections. Among the Japanese

    in California, regardless of smoking, dietor blood pressure, those with a morewesternised culture and social structurehad more heart disease than those where

    their culture was more traditionallyJapanese.

    Marmot conclusively demonstrateda link between social environment and

    disease rates setting the stage forall his subsequent research. Oered aposition at the London School of Hygieneand Tropical Medicine, a major centre

    of epidemiology, he began his famousWhitehall studies, researching rates ofheart disease in British public servants.The only social measure available for him

    WORDS

    FRAN MOLLOY

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    HEALTH SCIENCE

    SAM NOV 2010

    to investigate was peoples employment grade andthis delivered Marmot with a striking observation ofthe social gradient in health.

    Contrary to the popularly held opinion that high-status people experienced greater stress and were

    therefore at higher risk of heart attacks, Marmotfound that the lower a person was in the hierarchy,

    the higher their mortality from heart disease, and arange of other diseases. It wasnt just about poverty,

    Marmot says. It was a finely graded relation betweenwhere you were in the hierarchy and risk of disease.

    While some commentators blamed Britains classstructure, the Whitehall studies have since been

    reproduced all over the world, showing an inversegradient between social status and health. Marmots2004 book, The Status Syndrome: How Social StandingAects Our Health and Longevity, further expanded

    on these findings.Despite equal access to quality food, good housing

    and full employment, Marmot found that above acertain threshold of material well-being, another kind

    of well-being is central. The circumstances in whichwe live and work and our place in the social hierarchyaect our health and our longevity. The degree ofcontrol that each person has over their work and their

    life, and their level of social participation, will dictatetheir place on the gradient of health.

    Marmot says that he has spent the past 33 yearstrying to understand why it was that the higher a

    persons social status, the better their heath and todevelop policy to deal with this. Chairing the WHOGlobal Commission on the Social Determinants ofHealth, Marmot says that the Commissions most

    striking discovery was that non-communicabledisease dominated in almost every region of the world

    except the very poorest. It was a critical finding.This means that, if you think that the causes of

    disease are roughly the same wherever we find them,weve got to look for a set of common causes andcommon actions across the world.

    A critical global health threat is obesity, now

    ocially an epidemic, with over one billion peopleworldwide overweight, and around 300 millionclinically obese. Seventy per cent of women inEgypt are overweight or obese, says Marmot, while

    in Mexico, the problem of obesity far outweighsproblems of stunting and under-nutrition.

    Yet while obesity (which directly causes diabetes,heart disease and other health problems) is clearly

    part of a major global health crisis, its the causes ofobesity that are the real issue and breaking thesedown is complex.

    It relates to the nature of our food supply, the

    nature of opportunities for physical activity, thechanging nature of physical activity at work and howpeople make food choices, says Marmot.

    In the poorest countries, more educated women

    are more likely to be obese because in these countries,women with little education are so poor they donthave enough calories to eat. But in countries with

    a GDP higher than $2700, theres an inverseassociation, where women with more education areless likely to be obese.

    We can speculate on why its the case thatmore educated women in high income countriesare less likely to be obese, and its presumably inpart cognitive; its about fashion and the ability tocontrol your circumstances, what you eat, going tothe gym and so on, Marmot says.

    Marmot was then asked by the Britishgovernment to conduct a review of these findingsand make recommendations to reduce healthinequalities in Britain and in February 2010, his

    report, Fair Society, Healthy Lives was published.It was a statement that if we put fairness at

    the centre of all decision making, health wouldimprove and health and inequalities woulddiminish, Marmot says.

    World changing, indeed.