program - cost emf-medcost-emf-med.eu/.../emf-med-2018-program-booklet.pdf · • croatian...

1st EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields

& COST EMF-MED Final Event with 6th MCM

Split, 10-13 September 2018

PROGRAM &

Local Information

1

Organized By:

FESB, University of Split

Co-organized by:

• COST EMF-MED • European BioElectromagnetics Association (EBEA) • School of Medicine, University of Split (MEFST)

Endorsed by:

• International Federation for Medical and Biological Engineering (IFMBE)

• International Neuromodulation Society (INS) • The Bioelectromagnetics Society (BEMS) • European Society for Hyperthermic Oncology (ESHO) • Croatian Biomedical Engineering and Medical Physics

Society (CROBEMPS) • IEEE Croatia Section • IEEE Engineering in Medicine and Biology Croatia Chapter • IEEE Electromagnetic Compatibility Society Croatia

Chapter • IEEE Antennas and Propagation Society Croatia Chapter • IEEE Microwave Theory and Techniques Croatia Chapter

Venue:

FESB, University of Split, Ruđera Boškovića 32, 21000 Split, CROATIA Contact: [email protected] Conference Wi-Fi: "EMFMed", password: EMFMed2018 Eduroam is also available.

2

COMMITTEES

Organizing Committee / TPC Chairs:

• Antonio Šarolić (Croatia), Conference Chair • Mirjana Moser (Switzerland), Conference co-Chair • Gerard van Rhoon (The Netherlands) • Lluis Mir (France) • Niels Kuster (Switzerland) • Stavros Koulouridis (Greece)

Technical Program Committee:

Marioara Avram, Romania Almir Badnjević, Bosnia and

Herzegovina Jan Barabas, Slovakia John Bolte, The Netherlands Maria Inês Carvalho, Portugal Antonino Cassarà, Switzerland Raúl Chávez-Santiago, Norway Darko Chudy, Croatia Michal Cifra, Czech Republic Vedrana Čikeš Čulić, Croatia Jean-Francois Collard, Belgium Raquel Conceição, Portugal Luis Correia, Portugal Jan Cuppen, Netherlands Guglielmo d'Inzeo, Italy Nikola Djurić, Serbia Nebojsa Doncov, Serbia Lourdes Farrugia, Malta Peter Gajšek, Slovenia Nevzat Gençer, Turkey Dirk Geschwentner, Germany Motti Haridim, Israel Istvan Hernadi, Hungary Hiie Hinrikus, Estonia Andreas Ioannides, Cyprus Jukka Juutilainen, Finland Eugenijus Kaniusas, Austria

Leonardo Kapural, USA Jolanta Karpowicz, Poland Adnan Kaya, Turkey Leena Korpinen, Finland Stavros Koulouridis, Greece Niels Kuster, Switzerland Jaanus Lass, Estonia James Lin, USA Carmela Marino, Italy Natasa Markovska, FYR Macedonia Luc Martens, Belgium Arvydas Martinkenas, Lithuania Michael Mattes, Denmark Mats-Olof Mattsson, Sweden Alastair McKinlay, United Kingdom Simona Miclaus, Romania Damijan Miklavčič, Slovenia Lluis Mir, France Mihaela Morega, Romania Mirjana Moser, Switzerland Konstantina Nikita, Greece Martin O'Halloran, Ireland Yoram Palti, Israel Smiljana Paraš, Bosnia and

Herzegovina Leandro Pecchia, United Kingdom Daniela Pencheva, Bulgaria Yann Percherancier, France

3

Mikael Persson, Sweden Azadeh Peyman, United Kingdom Dragan Poljak, Croatia Nada Pop-Jordanova, FYR

Macedonia Victoria Ramos, Spain Giuseppe Ruvio, Ireland Theodoros Samaras, Greece Charles Sammut, Malta Damir Sapunar, Croatia Antonio Šarolić, Croatia

José L. Sebastián, Spain Hartwig Siebner, Denmark Myrtill Simko, Sweden Michal Teplan, Slovakia György Thuróczy, Hungary Hubert Trzaska, Poland Gerard van Rhoon, Netherlands Lyubina Vesselinova, Bulgaria David Vrba, Czech Republic Jonna Wilén, Sweden Gunde Ziegelberger, Germany

PROGRAM OUTLINE

Sunday, 9 September

16:00 - 20:00 Registration

Monday, 10 September

08:00 - 09:15 Registration

09:15 - 09:30 Conference Opening

09:30 - 18:00 Technical Program

18:00 - 20:00 Welcome cocktail

Tuesday, 11 September


17:15 - 19:30 COST Action BM1309 (EMF-MED) 6th Management Committee Meeting

Wednesday, 12 September


19:30 - 23:00 Conference dinner

Thursday, 13 September


11:30 - 12:30 Short courses

12:30 - 13:00 Closing ceremony

4

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6

WELCOME MESSAGE FROM THE CONFERENCE CHAIR

Dear EMF-Med 2018 Participants,

Welcome to beautiful Split, welcome to the first ever EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields! In a way, you are taking part in history making.

This conference was devised to serve as a vehicle, both driven by the expanding EMF-Med research and innovations, and providing a boost for them. Inspired by promising recent ideas and studies, EMF-Med focuses on medically applicable effects of EMFs, aiming for breakthrough results, new discoveries and innovative biomedical technologies.

Systematical approach to EMF-Med applications requires a dedicated community - a world-wide concerted R&D network - to sustain the required interdisciplinary knowledge: underlying biological mechanisms, knowledgeable engineering, reliable setups - having medical applications and patient benefit as the final goal. The EMF-Med Training School was also established to further sustain both the network and the knowledge.

The conference is also the final event of a research coordination project COST EMF-MED: European network for innovative uses of EMFs in biomedical applications. It ends soon, after having involved 35 countries and 350+ researchers. It started as a shy but bold idea in 2012 – to start the very first research initiative in the world to systematically and comprehensively approach the topic of beneficial effects of EMFs. This conference proves the ultimate success of this idea.

Wishing you a nice time in beautiful Split, and lots of ideas for the next conference,

Sincerely,

Antonio Šarolić Conference Chair on behalf of the Organizing Committee

7

KEYNOTE LECTURES

"EMF-Med: Electromagnetic medicine - a promise for the future" Prof. Antonio Šarolić, PhD Chair of COST EMF-MED; Professor of Electrical Engineering, FESB, University of Split, Croatia

"Vagus nerve stimulation" Peter S. Staats, MD, MBA Chief Medical Officer, National Spine and Pain Centers, USA

"Emerging waveforms in spinal cord stimulation for control of chronic pain" Leonardo Kapural, MD, PhD Pain Physician, Carolinas Pain Institute and Center for Clinical Research; Professor of Anesthesiology, Wake Forest University, School of Medicine, USA

"EMF in COST Actions: from risks to benefits" Mirjana Moser, PhD COST EMF-MED Vice-Chair, Switzerland

"An Overview of Medical Microwave Imaging" Raquel Cruz Conceição, PhD Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016-Lisbon, Portugal

8

"Challenges of medical devices using EMF for public health" Adriana Velázquez Berumen Senior Advisor and Focal Point for Medical Devices; Essential Medicines and Health Products department, World Health Organization (WHO), Geneva, Switzerland "EMF exposure from medical/cosmetic devices: Are standards needed?" Emilie van Deventer, PhD Team Leader, Radiation Programme, World Health Organization (WHO), Geneva, Switzerland

"Realizing the Vision of a Verified & Validated Computational Neurostimulation Platform" Prof. Niels Kuster, PhD COST EMF-MED WG3 Leader; Foundation for Research on Information Technologies in Society (IT’IS), Zurich, Switzerland; Swiss Federal Institute of Technology (ETH) Zurich, Switzerland

"Electromagnetic hyperthermia: Innovations and clinical applications" Prof Gerard van Rhoon, PhD COST EMF-MED WG1 Leader; Erasmus MC Cancer Institute, The Netherlands "Electroporation applications in medicine: from fundamentals to the clinics" Lluis M. Mir, DRCE CNRS COST EMF-MED WG2 Leader; Vectorology and Anticancer Therapies, UMR 8203 CNRS – University Paris-Saclay, France

9

CONFERENCE PROGRAM

Sunday, 9 September

Sunday, 9 September, 16:00 - 20:00 Room: Atrium

Registration

Monday, 10 September

Monday, 10 September, 8:00 - 9:15 Room: Atrium

Registration

Monday, 10 September, 9:15 - 9:30 Room: A100

Conference Opening


Keynote lecture KN1:

EMF-Med: Electromagnetic medicine - a promise for the future

Antonio Šarolić


Invited keynote lecture KN2:

Vagus nerve stimulation

Peter S. Staats

Monday, 10 September, 10:30 - 11:00 Room: Aquarium

Coffee break



Emerging waveforms in spinal cord stimulation for control of chronic pain

Leonardo Kapural

10


S1: Neural EMF applications and interactions

Chairs: Antonio Šarolić and Eugenijus Kaniusas 11:30 Patch-clamp recordings of strength-duration and strength-frequency curves in rat DRG neurons Alexandru Deftu, Damir Sapunar and Antonio Šarolić 11:45 Computational analysis of neural stimulation thresholds for several charge-balanced biphasic waveforms: a case study Antonio Šarolić, Dujo Benja, Marija Kovačić and Matej Kuliš 12:00 Assessment of nerve cathodal block for the percutaneous auricular vagus nerve stimulation Amine Samoudi, Tom Van de Steene, Emmeric Tanghe, Luc Martens and Wout Joseph

12:15 Individualized models of transcranial stimulation: connecting electrophysiological experiments with electric fields Ilkka Laakso and Marko Mikkonen

12:30 Comparison between direct electrical and optogenetic subthalamic nucleus stimulation Ruben Schoeters, Thomas Tarnaud, Wout Joseph, Luc Martens, Robrecht Raedt and Emmeric Tanghe

12:45 Brain stimulation by modulated microwave radiation: a feasibility study Maie Bachmann, Jaanus Lass, Andreas Ioannides and Hiie Hinrikus


Lunch


Poster session

Chairs: Stavros Koulouridis and Mirjana Moser P1 Repetitive transcranial magnetic stimulation can improve anxiety in Parkinson's disease: a randomized, double-blind and controlled trial Norbert Kovács, Endre Pál, Dávid Pintér, Márton Kovács and Attila Makkos

11

P2 Auricular vagus nerve stimulation affects fractality of the human body as resolved by advanced ECG Vaiva Siauciunaite, Eugenijus Kaniusas, Stefan Kampusch, Jozsef Constantin Szeles and Alfonsas Vainoras P3 Sensation and pain thresholds of transcranial stimulation with direct and alternating electric current Eugen Kvasnak and Kine Haldorsen Haugen P4 Peak-projection algorithm to target the phase of cortical oscillations in real-time Leo Tomašević and Hartwig Siebner P5 Assessment on electromagnetic hot-spots exposure caused by media control smart metering in a healthcare environment Victoria M Ramos, Angeles Trillo, Jose Hernandez, J Rabasa and Jolanta Karpowicz P6 Evaluation of the effect caused by hearing implants on SAR in a body approaching an RFID reader emitting at a frequency of 13.56 MHz Patryk Zradziński, Jolanta Karpowicz and Krzysztof Gryz P7 Role of magnetic flux density in LF EMF experiments targeting Ca2+, Na+ and K+ ions Jan Barabas, Roman Radil and Ladislav Janousek P8 Impedance measurement of bipolar stimulation electrodes immersed in medium Antonio Šarolić, Ivan Škalic, Alexandru Deftu and Damir Sapunar P9 Viability of human glioblastoma cell line LN229 exposed to rotating magnetic field Anton Kordić, Ornella Kordić, Vedrana Čikeš Čulić and Antonio Šarolić P10 Design and use of phased array RF systems for loco-regional hyperthermia of deep seated tumors Johannes Crezee, Remko Zweije and Petra Kok P11 Impact of segmentation detail in hyperthermia treatment planning: comparison between detailed and clinical tissue segmentation Iva Ribeiro, Netteke van Holthe, Gerard C. van Rhoon and Margarethus M. Paulides

12

P12 Modeling of Joule heating in tissues induced by high- and low-voltage pulse combinations for gene electrotransfer Igor Lacković P13 Linear Regression for Estimating Bladder Volume with Voltage Signals Eoghan Dunne, Adam Santorelli, Brian McGinley, Martin O'Halloran and Emily Porter P14 Multiclass SVM for Bladder Volume Monitoring using Electrical Impedance Measurements Adam Santorelli, Eoghan Dunne, Emily Porter and Martin O'Halloran P15 Cell viability changes in cultured H4 glioma cells upon low frequency pulsed electromagnetic field (7Hz, 30mT) exposure in flow cytometry analysis Jolanta Kaszuba-Zwoińska, Bernadeta Nowak, Piotr Guzdek and Krzysztof Gil P16 MRI compatible robotic system carrying a radio frequency probe to be used for brain ablation Christakis Damianou, Marinos Giannakou and Georgios Menikou P17 Effects of extremely low frequency electromagnetic fields on stem cells are not caused by zinc ions Alp Özgün and Bora Garipcan P18 Effects of radiofrequency fields on RAS and ERK kinases activity in live cells using the real-time Bioluminescence Resonance Energy Transfer (BRET) technique Emmanuelle Poque, Delia Arnaud-Cormos, Lorenza Patrignoni, Hermanus Ruigrok, Florence Poulletier De Gannes, Annabelle Hurtier, Rémy Renom, Lagroye Isabelle, Bernard Veyret, Philippe Leveque and Yann Percherancier P19 Cisplatin in-vitro activity with co-exposure to MRI Pol-Edern Le Renard, Benedikt Nimmervoll, Franz Fellner and Peter Oppelt P20 Strange effects of EMFs on living organisms Wlodzimierz Klonowski P21 Pancreatic β-cell hubs are more resistant to the environmental electromagnetic fields compared with non-hub cells: A computational study Sajjad Farashi, Pezhman Sasanpour and Hashem Rafii-Tabar

13

P22 Efficiency of Matrix Pencil Method in Stimulus Artifact Removal Zied Mizouri, Khalil El Khamlichi Drissi, Lenaïc Monconduit, Christophe Pasquier, Benoît Sion and François Gabrielli P23 Semi-rigid antenna working in ISM 2.4GHz used in microwave ablation Pawel Cala, Paweł Bieńkowski and Hubert Trzaska P24 50 Hz magnetic field affects heart rate variability - an experimental study Tarmo Koppel, Inese Vilcane and Mikko Ahonen P25 Modelling of therapeutic cold plasma generator using finite element method Ivan Moštak, Domagoj Prebeg and Mario Cifrek P26 Electrophysiological characterization of neurons after chronic compression of the dorsal root ganglion Tihana Marcius, Alexandru Deftu and Damir Sapunar P27 Patients with active implanted medical devices (AIMDs) and extremely low-frequency magnetic fields at hospital facilities Leena Korpinen and Rauno Pääkkönen P28 Exposure to the extremely low frequency magnetic field causes changes in Calcium flow, HSP70 and glutathione-disulfide reductase expression in breast cancer cells during apoptosis induction Alireza Madjid Ansari, Reyhane Ghadirian, Mahdieh Shokrollahi Barough and Zahra S. Mesbah Moosavi P29 Theranostic instrument based on the combination of low and high frequency EM-bio interaction for bone defects analysis and healing Anders Rydberg, Yongzhi Guo, Jacob Velander, Patrice Humblot, Göran Andersson, Robin Augustine, Mats-Olof Mattsson and Myrtill Simko P30 Simulated Effects of Specific Absorption Rate and Thermal Variations on Keratinocytes and Epidermis Exposed to Radio-Frequency Giacomo Paolini, Diego Masotti and Alessandra Costanzo P31 Comprehensive study of the effects of electromagnetic field exposure on nervous system using insect models Joanna Wyszkowska, Milena Jankowska and Maria Stankiewicz


Coffee break

14


Special session (convened by Caterina Merla and Cristiano Palego)

S2: EM-based micromanipulation of cells: towards unprecedented applications in medicine and biology

Chairs: Caterina Merla and Cristiano Palego 16:00 Molecular models for the interaction between high intense electric fields and biomolecules Paolo Marracino, Elena della Valle, Micaela Liberti and Francesca Apollonio

16:15 Microdosimetry in Biomedical Applications: Importance of Realistic Models at the Cellular and Subcellular Levels Micaela Liberti, Agnese Denzi, Caterina Merla, Francesca Apollonio, Annalisa De Angelis and Laura Caramazza

16:30 In vivo silencing gene for enhanced green fluorescent protein mediated by a pulsed electromagnetic field Matej Kranjc, Simona Kranjc, Maja Cemazar, Tadej Kotnik, Gregor Sersa and Damijan Miklavcic

16:45 Permittivity measurements of brain cancer cell solutions: towards the electric characterisation of single cancer stem cells Wesam Gamal, Rosanna Pinto, Mirella Tanori, Arianna Casciati, Mariateresa Mancuso, Luca Persano, Giampietro Viola, Sofiane Saada, Barbara Bessette, Fabrice Lalloue, Arnaud Pothier, Cristiano Palego and Caterina Merla

17:00 High-Frequency Dielectrophoresis Characterization of Differentiated vs Undifferentiated Medulloblastoma Cells Rémi Manczak, Sofiane Saada, Mirella Tanori, Arianna Casciati, Claire Dalmay, Barbara Bessette, Gaelle Begaud, Serge Battu, Pierre Blondy, Marie-Odile Jauberteau, Canan Baristiran-Kaynak, Mehmet Kaynak, Cristiano Palego, Caterina Merla, Barbara Tanno, Mariateresa Mancuso, Fabrice Lalloue and Arnaud Pothier

17:15 Single Pulses of Power at 14.5GHZ and a Weighted Slotted Antenna for the Treatment of Barrett's Oesophagus Christopher Paul Hancock

17:30 Cell membrane permeabilization and cell survival after electroporation in acidic media in vitro Tjaša Potočnik, Damijan Miklavcic and Alenka Maček Lebar

15

17:45 Toward a non-viral gene delivery approach for glycogen storage disease type III (GSDIII) therapy Rosella Franconi, Caterina Merla, Adeline Muscat, Doriana Triggiani, Olivia Costantina Demurtas, Elena Illiano, Franck M André, Carmela Marino and Lluis M. Mir


Welcome cocktail

Tuesday, 11 September

Tuesday, 11 September, 9:00 - 9:30 Room: A100


EMF in COST Actions: from risks to benefits

Mirjana Moser


S3: Beneficial interactions of EMFs with biological systems

Chairs: Mats-Olof Mattsson and Myrtill Simko 9:30 Study of gene expression on human keratinocytes after low frequency pulsed electric current stimulation Jean-Francois Collard and Maurice Hinsenkamp

9:45 Immune system activation by low frequency magnetic fields via the molecular sensor stromal interaction molecules (STIM1 and STIM2) Myrtill Simko

10:00 Diagnostic and therapeutic use, and use potential, of millimetre waves and terahertz waves Mats-Olof Mattsson

10:15 Protective effects of RF with different signal modulations in cultured human lymphocytes treated with chemicals Stefania Romeo, Anna Sannino, Olga Zeni, Rita Massa and Maria Rosaria Scarfì

Tuesday, 11 September, 10:30 - 11:00 Room: Aquarium

Coffee break

16



An overview of medical microwave imaging

Raquel Cruz Conceicao


Convened session (convened by Raquel C. Conceição and Lorenzo Crocco)

S4: Microwave Medical (MiMed) Imaging

Chairs: Raquel C. Conceição and Lourdes Farrugia 11:30 Development of Axillary Region Models based on MRI Segmented Data to Aid Breast Cancer Staging Daniela M. Godinho, Joao Felicio, Nuno Silva, M Lurdes Orvalho, Carlos A. Fernandes and Raquel C. Conceição

11:45 Preliminary Experimental Characterization of Gelatin-Based Tissue-Mimicking Materials for Realistic Breast Phantoms aimed at Microwave Applications Simona Di Meo, Simone Morganti, Lorenzo Pasotti, Michele Conti, Marco Pasian and Giulia Matrone

12:00 In-Vivo Mapping of Human Tissues From Only Amplitude Electromagnetic Data Martina Teresa Bevacqua, Gennaro G. Bellizzi, Lorenzo Crocco and Tommaso Isernia

12:15 Detection of Pneumothorax Using Low Power Microwave Sources Stavros Koulouridis

12:30 Remote mental workload estimation by a bioradar Lesya N. Anishchenko


Lunch

17


Convened session (convened by Lourdes Farrugia and Emily Porter)

S5: Electromagnetic-based Thermal Therapies (COST Action MyWAVE)

Chairs: Lourdes Farrugia and Raquel C. Conceição 14:00 Experimental evaluation of the effective ablation zone on ex-vivo bovine liver samples Anna Bottiglieri

14:15 Monitoring of microwave ablation treatment with electrical impedance tomography Konstantinos Katrioplas and Theodoros Samaras

14:30 Quality assurance of MR-guided deep hyperthermia systems: an international multi-institution evaluation Sergio Curto, Tim Mulder, Bassim Aklan, Oliver Mils, Manfred Schmidt, Ulf Lamprecht, Michael Peller, Ruediger Wessalowski, Lars Lindner, Rainer Fietkau, Daniel Zips, Margarethus M. Paulides, Martine Franckena and Gerard C. van Rhoon

14:45 Ex vivo dielectric properties of fat: influence of the experimental conditions on the measured data Laura Farina, Rosanna Pinto, Vanni Lopresto, Giuseppe Ruvio, Luca Vannucci and Marta Cavagnaro

15:00 A study on the variation of dielectric properties of grey matter with temperature Julian Bonello

15:15 The thermic response of biogenic magnetite suspensions to frequencies in the (0.1-3) GHz range Simona Miclaus, Paul Bechet, George Mihai, Ioan I. Ardelean, Cristina Moisescu and Jolanta Karpowicz


Coffee break

18


S6: Dielectric and magnetic properties of biological materials

Chairs: Azadeh Peyman and Lourdes Farrugia 16:00 An insight into bone dielectric properties variation: a foundation for electromagnetic medical devices Bilal Amin, Muhammad Adnan Elahi, Atif Shahzad, Eoin Parle, Laoise McNamara and Martin O'Halloran

16:15 Measurements of complex permittivity and permeability in the GHz range of magnetotactic bacteria suspensions Lourdes Farrugia, Simona Miclaus, Cristina Moisescu, Ioan I. Ardelean and Charles Sammut

16:30 Modelling of tissue dielectric contribution within the sensing radius of a coaxial probe Alessandra La Gioia, Martin O'Halloran and Emily Porter

16:45 In vivo electrical conductivity imaging of animal tumor model at 7T using electrical properties tomography Prakash Parappurath Vasudevan, Reza Aminzadeh, Nele De Geeter, Benedicte Descamps, Luc Dupré, Wout Joseph and Roel Van Holen


COST Action BM1309 (EMF-MED) 6th Management Committee Meeting

(only for COST Action BM1309 MC Members)

Wednesday, 12 September

Wednesday, 12 September, 9:00 - 9:15 Room: A100


Challenges of medical devices using EMF for public health

Adriana Velazquez Berumen



EMF exposure from medical/cosmetic devices: Are standards needed?

Emilie van Deventer

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S7: Electromagnetic safety of medical devices and procedures

Chairs: Mirjana Moser and Jolanta Karpowicz 9:30 Progress report: ICNIRP Statement on non-ionizing radiation for cosmetic purposes Rianne Stam, Ken Karipidis, Jacques Abramowicz, Guglielmo d'Inzeo, Adèle Green, Sharon Miller, Tsutomo Okuno and Tim Toivo

9:45 EMF Applications in Cosmetics and Wellness Gregor Dürrenberger, Krisztina Meya, Martin Schmid and Jürg Fröhlich

10:00 The exposimetric study on the radiofrequency exposures caused by the use of medical devices Jolanta Karpowicz, Victoria M Ramos, Krzysztof Gryz and Silvia de Miguel-Bilbao


Round table: WHO and EMF-Med: What can each contribute?

Wednesday, 12 September, 10:45 - 11:15 Room: Aquarium

Coffee break



Realizing the vision of a verified & validated computational neurostimulation platform

Niels Kuster


S8: Experimental setups and models for EMF-Med research

Chairs: Niels Kuster and Antonio Šarolić 11:45 In-Silico Ear Model Based on Episcopic Images for Percutaneous Auricular Vagus Nerve Stimulation Babak Dabiri Razlighi, Stefan Kampusch, Stefan H. Geyer, Van Hoang Le, Florian Thürk, Simon Brenner, Jozsef Constantin Szeles, Wolfgang J. Weninger and Eugenijus Kaniusas

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12:00 An algorithm for posturing computational phantoms Riccardo Scorretti

12:15 3D Printable Solid Tissue-Mimicking Material for Microwave Phantoms Barry McDermott, Emily Porter, Martin O'Halloran, Anup Poudel, Manus Biggs, Nireeksha Karode and Austin Coffey

12:30 Measurement of Weak Low Frequency Electromagnetic Field Effects on Cells Michal Teplan, Martin Bereta, Ivan Bajla, Katarína Bartošová, Tomáš Dermek, Yvonne Haba and Michal Cifra

12:45 Multimodal in vivo imaging of the mouse brain to test theranostic approaches including the biomedical applications of electromagnetic fields Srećko Gajović


Lunch


Convened session (convened by Valerio De Santis and Ilaria Liorni)

S9: EMF technologies for remotely powering wearable and implantable devices

Chairs: Valerio De Santis and Ilaria Liorni 14:00 Design of an Experimental Setup for Freely Positionable Coil Pairs for Transcutaneous Energy Transfer Systems Alexander Enssle, Laurenz Bareiss and Nejila Parspour

14:15 Design and Frequency Optimization of a WPT System for Leadless Medical Implants Tommaso Campi, Silvano Cruciani, Valerio De Santis, Francescaromana Maradei and Mauro Feliziani

14:25 Wearable Tag at 2.45 GHz for Continuous Tracking of Patients Activities in Indoor Environments Giacomo Paolini, Francesca Benassi, Diego Masotti and Alessandra Costanzo

14:35 Misalignments Issues in WPT Links for Medical Implants Giuseppina Monti, Laura Corchia, Beatrice Risolo and Luciano Tarricone

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Convened session (convened by Ilaria Liorni and Valerio De Santis)

S10: Electromagnetic safety of medical implants in MRI and medical WPT technologies

Chairs: Ilaria Liorni and Valerio De Santis 14:50 Assessment of the Risk of Neurostimulation by Low-Frequency EM Exposure in the Presence of Medical Implants Antonino Mario Cassara, Esra Neufeld, Ilaria Liorni and Niels Kuster

15:05 RF-field vs. Induced Heating with Interventional Catheters: a computational investigation Micol Colella, Elena Lucano, Francesca Apollonio, Qi Zeng, Jingshen Liu, Tom Lloyd, Steve Wedan, Ji Chen, Wolfgang Kainz, Micaela Liberti and Leonardo Angelone

15:20 New Mechanistic Model for Implant Safety Assessment at WPT Frequencies Ilaria Liorni, Esra Neufeld, Sven Kuhn and Niels Kuster


Coffee break



Electromagnetic hyperthermia: Innovations and clinical applications

Gerard van Rhoon


S11: Electromagnetic hyperthermia

Chairs: Gerard C. van Rhoon and Mihaela Morega 16:30 Development and In vivo Validation of an MR-Compatible Temperature Controllable Superficial Hyperthermia Applicator for Small Animal Studies Kemal Sumser, Anthony A.V. Geerman, Joost Haeck, Monique Bernsen, Gerard C. van Rhoon and Margarethus M. Paulides

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16:45 Water bolus investigation in conformal array for deep regional hyperthermia Redi Poni, Myles Capstick and Niels Kuster

17:00 Adaptive Treatment Planning for Locoregional Hyperthermia: A Necessary Tool for Optimizing Treatment Quality Petra Kok and Johannes Crezee

17:15 A Feasibility Study of Interstitial Microwaves Ablation and Hyperthermia by Numerical Simulation Mihaela Morega, Alexandru Mihail Morega and Alina Monica Ilie-Sandoiu

17:30 Sparsity Promoted Antenna Selection in Hyperthermia Treatment Planning Gennaro G. Bellizzi, Margarethus M. Paulides, Tomas Drizdal, Gerard C. van Rhoon, Lorenzo Crocco and Tommaso Isernia

17:45 Complex therapy by EMF and fractal physiology Andras Szasz

Wednesday, 12 September, 19:30 - 23:00

Conference dinner at the Cellars of the Diocletian's Palace (directions to the location are given at the end of the Program booklet)

Thursday, 13 September

Thursday, 13 September, 9:00 - 9:30 Room: A100


Electroporation applications in medicine: from fundamentals to the clinics

Lluis M. Mir

Thursday, 13 September, 9:30 - 11:00

S12: Cellular-level interactions with pulsed EMFs Room: A100

Chairs: Lluis M. Mir and Caterina Merla

9:30 Oxidative and Epigenetic Effects of Ultra-short Pulsed electric Fields on Neuronal-like Cells Claudia Consales, Caterina Merla, Barbara Benassi, Adeline Muscat, Tomas Garcia-Sanchez, Carmela Marino and Lluis M. Mir

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9:45 Nanosecond pulsed electric fields modulate Ca2+ fluxes in SHSY-5Y neuroblastoma cell line Caterina Merla, Tomas Garcia-Sanchez, Adeline Muscat, Claudia Consales, Barbara Benassi, Franck M André, Carmela Marino and Lluis M. Mir

10:15 Electrical stimulation increases schwann cells proliferation inside hyaluronic acid conduits Cristina Martinez Ramos, Maria Jose Morillo Bargues, Fernando Gisbert Roca, Laura Rodriguez Doblado, Esther Giraldo, Victoria Moreno and Manuel Monleon

17:45 Sine-wave electropermeabilization Tomas Garcia-Sanchez and Lluis M. Mir

10:30 Long term control of cytosolic calcium oscillations in Mesenchymal Stem Cells using repeated electric pulses Shirmoné Botha, Borja Lopez, Adeline Muscat, Óscar Lucía, Héctor Sarnago, Alejandro Naval, José-Miguel Burdio, Tomas Garcia-Sanchez, Lluis M. Mir and Franck M André

10:45 Zeta potential for monitoring posterior effects of the pulsed electric field in cell suspension Djamel Eddine Chafai and Michal Cifra

S13: Nanoparticles in EMF-Med applications Room: A101

Chairs: Theodoros Samaras and Gerard C. van Rhoon

9:30 Effects of spatial distribution patterns of magnetic nanoparticles on temperature distribution in magnetic hyperthermia Gurmeet Singh, Neeraj Kumar and Pramod Avti

9:45 Ex-vivo evaluation of magnetite magnetic nanoparticles as magnetic hyperthermia carriers Nikos Maniotis, Eirini Myrovali, Zoi Kalpaxidou, Charoula Iliaskou, Makis Angelakeris and Theodoros Samaras

10:00 Regional Focus effect on Magnetic Particle Hyperthermia efficiency Eirini Myrovali, Nikos Maniotis, Antonis Makridis, Kostantinos Simeonidis, Theodoros Samaras and Makis Angelakeris

10:15 Magnetotactic bacteria and biogenic magnetite nanocrystals as potential contrast agents in Magnetic Resonance Imaging Ioan Ardelean, Simona Miclaus, Ioan I. Ardelean and Cristina Moisescu

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10:30 Novel aspects of silver nanoparticles application in low intensity electromagnetic field Daniela Pencheva, Petia Genova-Kalou, Rayna Bryaskova, Lyubina Vesselinova, Todor Kantardjiev and Julian Ivanov Raynov

10:45 Can magnetic nanoparticles thermally assist the beneficiary role of transcranial magnetic stimulation? Tamara Odutola, Eirini Myrovali, Antonis Makridis, Nikos Maniotis, Makis Angelakeris, Vasilios Kimiskidis and Theodoros Samaras

Thursday, 13 September, 11:00 - 11:30 Room: Aquarium

Coffee break

Thursday, 13 September, 11:30 - 12:30

Short course SC1: Room: A101

Application of machine learning to medical data

Raquel Cruz Conceicao, Daniela M. Godinho

Short course SC2: Room: A100

Neuroimaging techniques in combination with Transcranial Magnetic Stimulation (TMS): state of the art and future perspectives

Hartwig Roman Siebner, Leo Tomašević

Thursday, 13 September, 12:30 - 13:00 Room: A100

Closing ceremony

Thursday, 13 September, 13:00 - 14:00 Room: Aquarium

Lunch

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LOCAL INFORMATION

About the city

Split - the Mediterranean city of life, where old meets new: founded as the Roman emperor Diocletian palace, now hosting the leading university in Croatia. It is the second largest city in Croatia, located on the Adriatic coast in the central Dalmatia, on the Split peninsula. A string of islands scattered in the crystal clear blue sea, make a magnificent frame around Split – make sure you take a look from the plane when arriving!

Centrally located on the Adriatic coast and well connected, Split provides the most convenient base to visit nearby beautiful Dalmatian islands, national parks, and other popular destinations like Dubrovnik, Trogir, Sibenik, Zadar, etc. The city is known for its climatic benefits (it has 2700 hours of sun a year), magical shades of the Marjan forest in the west part of the peninsula, and long seaside walkways.

The Diocletian’s Palace (under UNESCO’s protection since 1979), situated in the city center, dates from the 4th century and it is a unique site worldwide. The citizens still treasure traditional customs, leaving a pleasant and world-known feeling of welcome with their unique Mediterranean charm and delicious cuisine. Split, a city with almost 200.000 inhabitants, is one of the most important tourist destinations in Croatia and a significant cultural center.

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Tourist info

Split has recently been awarded as Croatia's Best City Break Destination and Best Destination of the Year 2017. For more information please visit the websites of the:

• Tourist Board of Split: http://visitsplit.com/en/ • Tourist Board of Dalmatia: https://www.dalmatia.hr/en • Tourist Board of Croatia: https://www.croatia.hr

Climate

Split has a Mediterranean climate with hot, moderately dry summers and mild, wet winters (snow is very rare). July is the hottest month, with an average high temperature around 30°C. January is the coldest month, with an average low temperature around 5°C. September is practically a summer month, providing plenty of beach time with more pleasant temperatures (less heat) than July and August (see weather statistics at https://www.yr.no/place/Croatia/Split-Dalmatia/Split/statistics.html ).

Currency

Croatia, although a EU member country, still has its own currency called Kuna (pronounced as koonnah, abbreviated as HRK or locally as "kn"). 1 Euro is worth approximately 7.4 Kuna. The currency can be exchanged in numerous change offices. The credit cards are widely accepted. However, tickets for the public transport can be paid by HRK cash only.

HOW TO GET TO SPLIT

By plane

Split is a highly popular tourist destination, served by Split Airport: http://www.split-airport.hr/. With ever increasing popularity of the destination, there is a wide selection of airlines during the summer season (September included). Split Airport (Zračna luka Split, code: SPU) is located 25 km from Split.

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The airport is connected to the Split main bus terminal (Autobusni kolodvor Split, situated in the city center), by shuttle bus. Shuttle ticket fare is 30 HRK ≈ 4 € for one direction, can be bought from the driver, only in HRK. There is also the option of online purchase at http://plesoprijevoz.hr/en/. The shuttle timetable can be found at: http://plesoprijevoz.hr/ page/timetable#split

The taxi fare Airport<->Split averages to ca. 250HRK ≈ 33€, but can be preordered for less, check the taxi companies online – a short list is given later, and it is highly advised to use only the official taxies.

COST participants: Please be aware of COST reimbursement restrictions concerning taxi transport!

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By car

The fastest and easiest way to get to Split by car is by using the A1 highway, which is part of international routes E65 and E71. You can also use D1 state road (no tolls, but slower). When you're approaching Split on A1, look for the exit Dugopolje and follow the signs that will direct you to Split. Use GPS to get to the venue, where there is plenty of free parking space (see the map).

By ferry

Split ferry port is the largest passenger port in Croatia. Ferry lines connect Split with the rest of Croatia like Dubrovnik, Rijeka and the islands, as well as with Italy: Ancona (daily) and Pescara. Split ferry port is easily accessible by all kinds of transportation - both the train station and the main bus terminal are located in the port area.

LOCAL BUS TRANSPORT ROUTES

The venue - FESB (Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture) - is a part of Split university campus and is located at Ruđera Boškovića 32, Split.

Local buses are operated by Promet Split d.o.o.: www.promet-split.hr

Bus tickets are sold by bus driver for 11 HRK, cash in HRK only. Double-ride tickets can be bought in kiosks for 18 HRK, or for 17 HRK if bought in bulk quantity (min. of 5). Tickets are valid for 45 minutes and can be used in any city bus that circulates through the city of Split.

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From downtown to campus (FESB) 1. Use the bus no. 18 or no. 11, either from their first stop HNK, or from the second stop Tržnica (outbound buses are on the west side of the street).

Bus station near Split national theatre (HNK)

West side of Zagrebačka street (Tržnica)

2. Both buses pass by FESB on Matice Hrvatske street. You should exit at the bus stop situated below the pedestrian bridge (5th bus stop counting from Tržnica, or 6th stop counting from HNK). If in doubt, ask for

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“Campus” or “FESB” (if asking locals, don't pronounce FESB as abbreviation, but as a word).

Pedestrian bridge near FESB, the street name is Matice Hrvatske

4. You are now on the south end of the pedestrian bridge, cross it to the north end and you shall see FESB faculty building in the front right direction.

FESB building

From campus (FESB) to downtown 1. From FESB walk back towards the pedestrian bridge, but before crossing it, turn right towards west and find your way down to the bus road (Matice Hrvatske). 2. Walking along the sidewalk, you will find the bus stop 200 m to the west of the bridge.

ENTRANCE

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The bus stop for no. 18 and no. 11 inbound route (from FESB to

downtown) 3. Take the bus no. 18 or no. 11 and exit on Tržnica or HNK (you cannot miss HNK since this is the last stop).

Main bus terminal (airport shuttle) → FESB (and viceversa) (e.g. if you are connecting directly from the airport to FESB, and viceversa)

Walk from the main bus terminal (Autobusni kolodvor Split), in the northbound direction about 450m to Tržnica, where you can take the bus no. 18 or no. 11 in the outbound direction (as described before). Viceversa: coming from FESB by bus, exit at Tržnica and walk 450m to the main bus terminal.

Tržnica

Main bus terminal

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If you want to avoid this walking, you can take the bus no. 2, 9, 10 or 15 for just 1 stop from the main bus terminal to Tržnica, but to catch this bus, you have to walk about 150m in the southbound direction. Viceversa: coming from FESB by bus, exit at Tržnica, cross the street to the west side, and there take the bus no. 2, 9, 10 or 15 for just 1 stop, then walk back about 150m to the main bus terminal.

TAXI SERVICE IN SPLIT

You can find a wide selection of taxi companies, with varying prices, depending also on the way of ordering (on street, online, phone call), but generally very affordable, e.g.:

• Cammeo: 5 kn start, 5 kn per km, https://cammeo.hr/hr/gradovi/split , +385 21 313 313,

• Yellow cab: 5 kn start, 8 kn per km, https://www.zutitaxisplit.com/, +385 21 208 208,

• GoGreen: 9 kn start, 9 kn per km, http://gogreentaxisplit.hr , +385 21 772 772,

• Uber is operational in Split, and you can search online for other companies and pre-ordered transfers.

For your orientation, driving distance from Riva (downtown) to FESB is ca. 4 km, so the ride should cost 4-5 € according to the prices above (as advertised on the web sites). COST participants: Please be aware of COST reimbursement restrictions concerning taxi transport!

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ACCOMMODATION IN SPLIT

EMF-Med does not provide accommodation recommendations or reservations. There is an extensive selection of accommodation on the major booking web sites, such as Booking.com, Hotels.com, Airbnb.com and others. If you need personalized service related to your accommodation, information can be requested from the company GALAXY TRAVEL d.o.o. (www.galaxy-travel.hr) that manages the registrations on behalf of FESB, University of Split. This company is also a travel agency, and can provide accommodation services at a request, as a part of their own everyday business.

COST EMF-MED participants have a special arrangement for accommodation in the campus dorm "Franjo Tuđman" (shown below), which is managed through dedicated communication in the COST Action.

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CONFERENCE DINNER Wednesday, 12 September at 19:30h, at the Cellars of the Diocletian's Palace (west wing)

Find the Cellars southern entrance situated on Riva (the famous waterfront promenade). Enter from Riva into the Cellars, then immediately turn left and enter to the west wing through the large metal gate.

The Cellars (Podrumi) are a substructure below the Diocletian’s apartment in the southern quarter of the Palace. By converting the palace into the city of Split, most of the residential complex was demolished but the ground floor halls were perfectly preserved. In the early Middle Ages a part of the complex was inhabited, and in one of the halls wine and oil were produced. Today the Cellars are accessible through the Brass Gate of the Palace (from Riva), or through a staircase from the Peristyle. The Western part of the basement has been preserved in its entirety and is almost completely accessible for sightseeing. The Eastern part has collapsed during Middle Age but has been excavated and a large part is also accessible.

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Save the date!

2nd EMF-Med World Conference

& Training School on Biomedical Applications of Electromagnetic Fields

Split, 7-12 September 2020

Contribute to development and optimization of innovative EMF-based medical devices and procedures, which will be safer, more efficient and less invasive!

EMF-Med 2020

program - cost emf-medcost-emf-med.eu/.../emf-med-2018-program-booklet.pdf · • croatian...

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