project title: environmental pathology/toxicology … · michael t p30es007033, t32es007032 part...

Project Title: ENVIRONMENTAL PATHOLOGY/TOXICOLOGY TRAININGPROGRAM

PI: Faustman, Elaine M Institution: University Of Washington

GrantNumber: T32ES007032

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Publication Title Authors GrantNumber(s)

Journal (Pubdate)

PubMedLink

PubYear

Anchoring a dynamic in vitro model ofhuman neuronal differentiation to keyprocesses of early brain ...

Wegner, SusannaH; Park, JulieJuyoung;Workman,Tomomi; Hermsen,Sanne A B;Wallace, Jim; Stan...

P30ES007033,T32ES007032,T32ES015459

Reprod Toxicol(2020 01)

31740287

2020

Effects of air pollution on the nervoussystem and its possible role inneurodevelopmental and neuro ...

Costa, Lucio G;Cole, Toby B; Dao,Khoi; Chang,Yu-Chi; Coburn,Jacki; Garrick,Jacqueline M

P30ES007033,P42ES004696,R01ES028273,T32ES007032

Pharmacol Ther(2020 06)

32165138

2020

The Effects of Gene-EnvironmentInteractions Between Cadmium Exposureand Apolipoprotein E4 on Memor ...

Zhang, Liang;Wang, Hao; Abel,Glen M; Storm,Daniel R; Xia,Zhengui

P42ES004696,T32ES007032

Toxicol Sci (202001 01)

31626305

2020

The effects of genotype × phenotypeinteractions on silver nanoparticle toxicityin organotypic cult ...

Nicholas, Tyler P;Haick, Anoria K;Workman, TomomiW; Griffith,William C; Nolin,James D; Kav ...

P30ES007033,T32ES007032

Nanotoxicology(2020 09)

32574512

2020

Characterization of the Impact of DrugMetabolism on the Gas-Phase Structuresof Drugs Using Ion Mob ...

Ross, Dylan H;Seguin, Ryan P;Xu, Libin

T32ES007032 Anal Chem (201911 19)

31613088

2019

DDS promotes longevity through amicrobiome-mediated starvation signal.

Choi, Haeri; Cho,Sung Chun; Ha,Young Wan;Ocampo, Billie;Park, Shirley;Chen, Shiwen;Benne ...

T32ES007032 Transl MedAging (2019)

32190786

2019

Developmental impact of air pollution onbrain function.

Costa, Lucio G;Cole, Toby B; Dao,Khoi; Chang,Yu-Chi; Garrick,Jacqueline M

P30ES007033,R01ES028273,T32ES007032

Neurochem Int(2019 12)

31626830

2019

Dynamics of a hippocampal neuronalensemble encoding trace fear memoryrevealed by in vivo Ca2+ imag ...

Zhang, Liang;Chen, Xuanmao;Sindreu, Carlos;Lu, Song; Storm,Daniel R; Zweifel,Larry S; Xia ...

P42ES004696,T32ES007032

PLoS One (2019) 31269057

2019

Human CD4+ T Cells Specific for MerkelCell Polyomavirus Localize to MerkelCell Carcinomas and Targ ...

Longino, NatalieV; Yang, Junbao;Iyer, Jayasri G;Ibrani, Dafina;Chow, I-Ting;Laing, Kerry ...

T32ES007032 Cancer ImmunolRes (2019 10)

31405946

2019

In utero exposure to diesel exhaust isassociated with alterations in neonatalcardiomyocyte transcr ...

Goodson, Jamie M;MacDonald, JamesW; Bammler, TheoK; Chien,Wei-Ming; Chin,Michael T

P30ES007033,T32ES007032

Part Fibre Toxicol(2019 04 11)

30975218

2019

Metabolism of Benzalkonium Chloridesby Human Hepatic Cytochromes P450.

Seguin, Ryan P;Herron, Josi M;Lopez, Vanessa A;Dempsey, JosephL; Xu, Libin

P30ES007033,T32ES007032

Chem ResToxicol (2019 1216)

31730751

2019

Multi-omics investigation revealsbenzalkonium chloride disinfectants altersterol and lipid homeost ...

Herron, Josi M;Hines, Kelly M;Tomita, Hideaki;Seguin, Ryan P;Cui, Julia Yue; Xu,Libin

P30ES007033,T32ES007032

Toxicol Sci (2019Jun 14)

31199489

2019

Pharmacological Activation of PXR andCAR Downregulates Distinct BileAcid-Metabolizing Intestinal B ...

Dempsey, JosephL; Wang,Dongfang; Siginir,Gunseli; Fei,Qiang; Raftery,Daniel; Gu,Haiwei; ...

P30ES007033,T32ES007032

Toxicol Sci (201903 01)

30407581

2019

Polybrominated Diphenyl Ethers and GutMicrobiome Modulate MetabolicSyndrome-Related Aqueous Metabo ...

Scoville, David K;Li, Cindy Yanfei;Wang, Dongfang;Dempsey, JosephL; Raftery, Daniel;Mani, ...

P30ES007033,R01ES030197,T32ES007032

Drug MetabDispos (2019 08)

31123037

2019

Regulation of Hepatic Long NoncodingRNAs by Pregnane X Receptor andConstitutive Androstane Recepto ...

Dempsey, JosephL; Cui, Julia Yue

P30ES007033,T32ES007032


30593543

2019

The Effects of Gene × EnvironmentInteractions on Silver NanoparticleToxicity in the Respiratory Sy ...

Nicholas, Tyler P;Kavanagh,Terrance J;Faustman, ElaineM; Altemeier,William A

T32ES007032 Chem ResToxicol (2019 0617)

31124663

2019

A High-Throughput Screen IdentifiesDYRK1A Inhibitor ID-8 that StimulatesHuman Kidney Tubular Epith ...

Monteiro, Maria B;Ramm, Susanne;Chandrasekaran,Vidya; Boswell,Sarah A; Weber,Elijah J; Lid ...

P30ES007033,R01ES017543,R01ES017543,T32ES007032

J Am SocNephrol (201812)

30361326

2018

Adverse metabolic effects in fish exposedto contaminants of emerging concern inthe field and labor ...

Meador, James P;Yeh, Andrew;Gallagher, Evan P

P42ES004696,T32ES007032

Environ Pollut(2018 May)

29471284

2018

Assessment of Altered CholesterolHomeostasis by Xenobiotics UsingUltra-High Performance Liquid Chr ...

Herron, Josi;Hines, Kelly M;Xu, Libin

T32ES007032 Curr ProtocToxicol (2018 11)

30320450

2018

Coordinate regulation of long non-codingRNAs and protein-coding genes ingerm-free mice.

Dempsey, Joseph;Zhang, Angela;Cui, Julia Yue

P30ES007033,T32ES007032

BMC Genomics(2018 Nov 21)

30463508

2018

Human kidney on a chip assessment ofpolymyxin antibiotic nephrotoxicity.

Weber, Elijah J;Lidberg, Kevin A;Wang, Lu;Bammler, Theo K;MacDonald, JamesW; Li, Mavis J; ...

P30ES007033,T32ES007032

JCI Insight (201812 20)

30568031

2018

In vitro to in vivo benchmark dosecomparisons to inform risk assessment ofquantum dot nanomaterial ...

Weldon, BrittanyA; Griffith,William C;Workman,Tomomi; Scoville,David K;Kavanagh,Terrance ...

P30ES007033,T32ES007032,T32ES015459

Wiley InterdiscipRev NanomedNanobiotechnol(2018 07)

29350469

2018

Merkel Cell Carcinoma PatientsPresenting Without a Primary LesionHave Elevated Markers of Immunity ...

Vandeven, Natalie;Lewis, ChristopherW; Makarov,Vladimir; Riaz,Nadeem; Paulson,Kelly G; Hip ...

T32ES007032 Clin Cancer Res(2018 02 15)

29246939

2018

PBDEs Altered Gut Microbiome and BileAcid Homeostasis in Male C57BL/6 Mice.

Li, Cindy Yanfei;Dempsey, JosephL; Wang,Dongfang; Lee,SooWan; Weigel,Kris M; Fei,Qiang; ...

P30ES007033,T32ES007032


29769268

2018

Prevention of Retinal Degeneration in aRat Model of Smith-Lemli-OpitzSyndrome.

Fliesler, Steven J;Peachey, Neal S;Herron, Josi;Hines, Kelly M;Weinstock, NadavI; Ramachan ...

T32ES007032 Sci Rep (2018 0119)

29352199

2018

Assessment of altered lipid homeostasisby HILIC-ion mobility-massspectrometry-based lipidomics.

Hines, Kelly M;Herron, Josi; Xu,Libin

P30ES007033,T32ES007032

J Lipid Res (201704)

28167702

2017

Behavioral Phenotyping for AutismSpectrum Disorders in Mice.

Chang, Yu-Chi;Cole, Toby B;Costa, Lucio G

P30ES007033,P42ES004696,R01ES028273,T32ES007032

Curr ProtocToxicol (2017May 02)

28463420

2017

Determining potential adverse effects inmarine fish exposed to pharmaceuticalsand personal care pr ...

Meador, James P;Yeh, Andrew;Gallagher, Evan P

P42ES004696,T32ES007032

Environ Pollut(2017 Nov)

28764109

2017

Developmental Neurotoxicity ofTraffic-Related Air Pollution: Focus onAutism.

Costa, Lucio G;Chang, Yu-Chi;Cole, Toby B

P30ES007033,P42ES004696,R01ES028273,T32ES007032

Curr EnvironHealth Rep (201706)

28417440

2017

Effect of contaminants of emergingconcern on liver mitochondrial function inChinook salmon.

Yeh, Andrew;Marcinek, David J;Meador, James P;Gallagher, Evan P

P42ES004696,T32ES007032

Aquat Toxicol(2017 Sep)

28668760

2017

In utero exposure to diesel exhaustparticulates is associated with an alteredcardiac transcription ...

Goodson, Jamie M;Weldy, Chad S;MacDonald, JamesW; Liu, Yonggang;Bammler, Theo K;Chien, We ...

P30ES007033,T32ES007032

FASEB J (201711)

28751527

2017

Neurotoxicity of traffic-related airpollution.

Costa, Lucio G;Cole, Toby B;Coburn, Jacki;Chang, Yu-Chi;Dao, Khoi; Roqué,Pamela J

P30ES007033,P42ES004696,T32ES007032

Neurotoxicology(2017 03)

26610921

2017

Tumor-Infiltrating Merkel CellPolyomavirus-Specific T Cells AreDiverse and Associated with Improve ...

Miller, Natalie J;Church, CandiceD; Dong, Lichun;Crispin, David;Fitzgibbon,Matthew P; Lach ...

T32ES007032 Cancer ImmunolRes (2017 Feb)

28093446

2017

Age-related arterial telomere uncappingand senescence is greater in womencompared with men.

Walker, Ashley E;Morgan, R Garrett;Ives, Stephen J;Cawthon, RichardM; Andtbacka,Robert H I ...

T32ES007032 Exp Gerontol(2016 Jan)

26602606

2016

Aneuploidy shortens replicative lifespan inSaccharomyces cerevisiae.

Sunshine, Anna B;Ong, Giang T;Nickerson, DanielP; Carr, Daniel;Murakami,Christopher J; Was...

T32ES007032 Aging Cell (2016Apr)

26762766

2016

Contaminants of emerging concern in alarge temperate estuary.

Meador, James P;Yeh, Andrew;Young, Graham;Gallagher, Evan P

P42ES004696,T32ES007032

Environ Pollut(2016 Jun)

26907702

2016

From the Cover: Cadmium ExposureDifferentially Alters Odorant-DrivenBehaviors and Expression of Ol ...

Williams, Chase R;MacDonald, JamesW; Bammler, TheoK; Paulsen,Michael H;Simpson,Christophe ...

P30ES007033,P42ES004696,T32ES007032

Toxicol Sci (201612)

27621283

2016

Genetic association of long-chainacyl-CoA synthetase 1 variants withfasting glucose, diabetes, and ...

Manichaikul, Ani;Wang, Xin-Qun;Zhao, Wei;Wojczynski, MaryK; Siebenthall,Kyle;Stamatoyanno ...

T32ES007032 J Lipid Res (2016Mar)

26711138

2016

Identification of EnvironmentalQuaternary Ammonium Compounds asDirect Inhibitors of Cholesterol Bi ...

Herron, Josi;Reese, Rosalyn C;Tallman, Keri A;Narayanaswamy,Rohini; Porter, NedA; Xu, Lib ...

T32ES007032 Toxicol Sci (201606)

26919959

2016

Merkel Cell Carcinoma: An UnusuallyImmunogenic Cancer Proves Ripe forImmune Therapy.

Vandeven, NatalieA; Nghiem, Paul

T32ES007032 J Oncol Pract(2016 07)

27407162

2016

Mortalin is Expressed by Astrocytes andDecreased in the Midbrain of Parkinson'sDisease Patients.

Cook, Travis J;Hoekstra, Jake G;Eaton, David L;Zhang, Jing

T32ES007032,T32ES015459

Brain Pathol(2016 Jan)

26095919

2016

Olfactory Transcriptional Analysis ofSalmon Exposed to Mixtures ofChlorpyrifos and Malathion Revea ...

Wang, Lu;Espinoza, HerbertM; MacDonald,James W;Bammler, Theo K;Williams, Chase R;Yeh, An ...

P30ES007033,P42ES004696,T32ES007032

Toxicol Sci (2016Jan)

26494550

2016

Phthalate metabolism and kinetics in an invitro model of testis development.

Harris, Sean;Wegner, Susanna;Hong, Sung Woo;Faustman, ElaineM

P30ES007033,T32ES007032

Toxicol In Vitro(2016 Apr)

26689326

2016

Rationale for immune-based therapies inMerkel polyomavirus-positive and-negative Merkel cell carci ...

Vandeven, Natalie;Nghiem, Paul

T32ES007032 Immunotherapy(2016 07)

27381685

2016

Sex and genetic differences in the effectsof acute diesel exhaust exposure oninflammation and oxid ...

Cole, Toby B;Coburn, Jacki;Dao, Khoi; Roqué,Pam; Chang,Yu-Chi; Kalia,Vrinda; Guilarte, T...

P30ES007033,P42ES004696,R01ES007062,T32ES007032,T32ES007062

Toxicology (2016Dec 30)

27865893

2016

Transcriptome profiling of equine vitaminE deficient neuroaxonal dystrophyidentifies upregulation ...

Finno, Carrie J;Bordbari, MatthewH; Valberg,Stephanie J; Lee,David; Herron,Josi; Hines, K ...

T32ES007032 Free Radic BiolMed (2016 12)

27751910

2016

A Comprehensive Analysis of ReplicativeLifespan in 4,698 Single-Gene DeletionStrains Uncovers Cons ...

McCormick, MarkA; Delaney, Joe R;Tsuchiya,Mitsuhiro;Tsuchiyama, Scott;Shemorry, Anna;Sim, ...

T32ES007032 Cell Metab (2015Nov 03)

26456335

2015

Air pollution and adverse cardiacremodeling: clinical effects and basicmechanisms.

Liu, Yonggang;Goodson, Jamie M;Zhang, Bo; Chin,Michael T

T32ES007032 Front Physiol(2015)

26042051

2015

Astrocytic dynamin-like protein 1regulates neuronal protection againstexcitotoxicity in Parkinson ...

Hoekstra, Jake G;Cook, Travis J;Stewart, Tessandra;Mattison, Hayley;Dreisbach, Max T;Hoffe ...

P30ES007033,P42ES004696,T32ES007032,T32ES015459

Am J Pathol(2015 Feb)

25482923

2015

Biochemical Genetic Pathways thatModulate Aging in Multiple Species.

Bitto, Alessandro;Wang, AdrienneM; Bennett,Christopher F;Kaeberlein, Matt

T32ES007032 Cold Spring HarbPerspect Med(2015 Nov)

26525455

2015

Cellular and molecular biology of agingendothelial cells.

Donato, Anthony J;Morgan, R Garrett;Walker, Ashley E;Lesniewski, Lisa A

T32ES007032 J Mol CellCardiol (2015Dec)

25655936

2015

Cerebrospinal fluid peptides as potentialParkinson disease biomarkers: a stagedpipeline for discov ...

Shi, Min; Movius,James; Dator,Romel; Aro,Patrick; Zhao,Yanchun; Pan,Catherine; Lin,Xian ...

P30ES007033,P42ES004696,T32ES007032,T32ES015459

Mol CellProteomics (2015Mar)

25556233

2015

Chemical characterization and in vitrotoxicity of diesel exhaust particulate mattergenerated under ...

Fox, JulieRichman; Cox,David P; Drury,Bertram E; Gould,Timothy R;Kavanagh,Terrance J; Pau ...

P30ES007033,T32ES007032,T32ES015459

Air Qual AtmosHealth (2015 Oct01)

26539254

2015

Defining Molecular Basis for LongevityTraits in Natural Yeast Isolates.

Kaya, Alaattin; Ma,Siming; Wasko,Brian; Lee,Mitchell;Kaeberlein, Matt;Gladyshev, VadimN

T32ES007032 NPJ Aging MechDis (2015)

27030810

2015

DNase I hypersensitivity analysis of themouse brain and retina identifiesregion-specific regulator ...

Wilken, MatthewS; Brzezinski,Joseph A; LaTorre, Anna;Siebenthall, Kyle;Thurman, Robert;Sa ...

T32ES007032 EpigeneticsChromatin (2015)

25972927

2015

Glutamate Cysteine Ligase ModifierSubunit (Gclm) Null Mice Have IncreasedOvarian Oxidative Stress ...

Lim, Jinhwan;Nakamura, BrookeN; Mohar, Isaac;Kavanagh,Terrance J;Luderer, Ulrike

P30ES007033,R01ES020454,R01ES020454,T32ES007032

Endocrinology(2015 Sep)

26083875

2015

H3K36 methylation promotes longevity byenhancing transcriptional fidelity.

Sen, Payel; Dang,Weiwei; Donahue,Greg; Dai, Junbiao;Dorsey, Jean; Cao,Xiaohua; Liu, Wei;...

T32ES007032 Genes Dev (2015Jul 1)

26159996

2015

Integrative analysis of 111 referencehuman epigenomes.

RoadmapEpigenomicsConsortium;Kundaje, Anshul;Meuleman,Wouter; Ernst,Jason; Bilenky,Misha; ...

T32ES007032 Nature (2015 Feb19)

25693563

2015

Phosphorylated α-synuclein in Parkinson'sdisease: correlation depends on diseaseseverity.

Stewart, Tessandra;Sossi, Vesna;Aasly, Jan O;Wszolek, ZbigniewK; Uitti, Ryan J;Hasegawa, ...

P30ES007033,P42ES004696,T32ES007032,T32ES015459

Acta NeuropatholCommun (2015Jan 31)

25637461

2015

Prostaglandin E2 receptor subtype 2regulation of scavenger receptor CD36modulates microglial Aβ42 ...

Li, Xianwu;Melief, Erica;Postupna, Nadia;Montine, KathleenS; Keene, C Dirk;Montine, Thoma ...

T32ES007032 Am J Pathol(2015 Jan)

25452117

2015

Relative contributions of severedopaminergic neuron ablation anddopamine depletion to cognitive im ...

Morgan, R Garrett;Gibbs, Jeffrey T;Melief, Erica J;Postupna, Nadia O;Sherfield, Emily E;Wi ...

T32ES007032 Exp Neurol (2015Sep)

26079646

2015

Single-fraction radiation therapy inpatients with metastatic Merkel cellcarcinoma.

Iyer, Jayasri G;Parvathaneni,Upendra; Gooley,Ted; Miller,Natalie J;Markowitz, Elan;Blom, ...

T32ES007032 Cancer Med(2015 Aug)

25908228

2015

Tether mutations that restore function andsuppress pleiotropic phenotypes of the C.elegans isp-1(q ...

Jafari, Gholamali;Wasko, Brian M;Tonge, Ashley;Schurman, Nathan;Dong, Cindy; Li,Zhongyu; ...

T32ES007032 Proc Natl AcadSci U S A (2015Nov 10)

26504246

2015

Transcription errors induce proteotoxicstress and shorten cellular lifespan.

Vermulst, Marc;Denney, Ashley S;Lang, Michael J;Hung, Chao-Wei;Moore, Stephanie;Moseley, ...

T32ES007032 Nat Commun(2015 Aug 25)

26304740

2015

α-Synuclein, a chemoattractant, directsmicroglial migration via H2O2-dependentLyn phosphorylation.

Wang, Shijun;Chu, Chun-Hsien;Stewart, Tessandra;Ginghina, Carmen;Wang, Yifei; Nie,Hui; Gu ...

T32ES007032 Proc Natl AcadSci U S A (2015Apr 14)

25825709

2015

Acetaminophen-induced liver damage inmice is associated with gender-specificadduction of peroxired ...

Mohar, Isaac;Stamper, BrendanD; Rademacher,Peter M; White,Collin C; Nelson,Sidney D; Kavan ...

P30ES007033,P42ES004696,T32ES007032

Redox Biol(2014)

24563856

2014

Activation of the mitochondrial unfoldedprotein response does not predict longevityin Caenorhabdit ...

Bennett,Christopher F;Vander Wende,Helen; Simko,Marissa; Klum,Shannon; Barfield,Sarah; Ch ...

T32ES007032 Nat Commun(2014 Mar 24)

24662282

2014

Astrocytes protect against diazinon- anddiazoxon-induced inhibition of neuriteoutgrowth by regulat ...

Pizzurro, DaniellaM; Dao, Khoi;Costa, Lucio G

P30ES007033,T32ES007032

Toxicology (2014Apr 6)

24561003

2014

Diazinon and diazoxon impair the abilityof astrocytes to foster neurite outgrowth inprimary hippoc ...

Pizzurro, DaniellaM; Dao, Khoi;Costa, Lucio G

P30ES007033,T32ES007032

Toxicol ApplPharmacol (2014Feb 01)

24342266

2014

Human valacyclovir hydrolase/biphenylhydrolase-like protein is a highly efficienthomocysteine thio ...

Marsillach, Judit;Suzuki, StephanieM; Richter,Rebecca J;McDonald,Matthew G;Rademacher, Pe ...

P42ES004696,T32ES007032

PLoS One (2014) 25333274

2014

Neurotoxicants are in the air: convergenceof human, animal, and in vitro studies onthe effects of ...

Costa, Lucio G;Cole, Toby B;Coburn, Jacki;Chang, Yu-Chi;Dao, Khoi; Roque,Pamela

P30ES007033,T32ES007032

Biomed Res Int(2014)

24524086

2014

Rare coding variation in paraoxonase-1 isassociated with ischemic stroke in theNHLBI Exome Sequenc ...

Kim, Daniel Seung;Crosslin, David R;Auer, Paul L;Suzuki, StephanieM; Marsillach,Judit; Bur ...

T32ES007032 J Lipid Res (201406)

24711634

2014

Searching for the elusive mitochondriallongevity signal in C. elegans.

Bennett,Christopher F;Choi, Haeri;Kaeberlein, Matt

T32ES007032 Worm (2014Jul-Sep)

26430544

2014

The mitochondrial unfolded proteinresponse and increased longevity: cause,consequence, or correlat ...

Bennett,Christopher F;Kaeberlein, Matt

T32ES007032 Exp Gerontol(2014 Aug)

24518875

2014

Yeast replicative aging: a paradigm fordefining conserved longevityinterventions.

Wasko, Brian M;Kaeberlein, Matt

T32ES007032 FEMS Yeast Res(2014 Feb)

24119093

2014

A disintegrin and metalloproteinase 17regulates TNF and TNFR1 levels ininflammation and liver rege ...

McMahan, Ryan S;Riehle, Kimberly J;Fausto, Nelson;Campbell, Jean S

T32ES007032 Am J PhysiolGastrointest LiverPhysiol (2013 Jul01)

23639813

2013

Biomarkers of Parkinson's disease: currentstatus and future perspectives.

Wang, Jian;Hoekstra, Jake G;Zuo, Chuantao;Cook, Travis J;Zhang, Jing

P30ES007033,P42ES004696,T32ES007032,T32ES015459

Drug DiscovToday (2013 Feb)

22982303

2013

Dietary restriction and mitochondrialfunction link replicative and chronologicalaging in Saccharom ...

Delaney, Joe R;Murakami,Christopher; Chou,Annie; Carr,Daniel; Schleit,Jennifer; Sutphin,...

T32ES007032 Exp Gerontol(2013 Oct)

23235143

2013

Effects of cadmium on olfactory mediatedbehaviors and molecular biomarkers incoho salmon (Oncorhyn ...

Williams, Chase R;Gallagher, Evan P

P42ES004696,T32ES007032

Aquat Toxicol(2013 Sep 15)

23851056

2013

Emerging and mechanism-based therapiesfor recurrent or metastatic Merkel cellcarcinoma.

Miller, Natalie J;Bhatia, Shailender;Parvathaneni,Upendra; Iyer,Jayasri G; Nghiem,Paul

T32ES007032 Curr TreatOptions Oncol(2013 Jun)

23436166

2013

End-of-life cell cycle arrest contributes tostochasticity of yeast replicative aging.

Delaney, Joe R;Chou, Annie;Olsen, Brady; Carr,Daniel; Murakami,Christopher;Ahmed, Umema; ...

T32ES007032 FEMS Yeast Res(2013 May)

23336757

2013

Enhancement of hepatic 4-hydroxylationof 25-hydroxyvitamin D3 throughCYP3A4 induction in vitro and ...

Wang, Zhican; Lin,Yvonne S;Dickmann, LeslieJ; Poulton,Emma-Jane; Eaton,David L; Lampe,Jo ...

P30ES007033,T32ES007032

J Bone Miner Res(2013 May)

23212742

2013

Glutathione (GSH) and the GSH synthesisgene Gclm modulate plasma redox andvascular responses to ac ...

Weldy, Chad S;Luttrell, Ian P;White, Collin C;Morgan-Stevenson,Vicki; Cox, DavidP; Carosin ...

P30ES007033,T32ES007032

Inhal Toxicol(2013 Jul)

23808636

2013

Heme oxygenase expression as abiomarker of exposure to amphiphilicpolymer-coated CdSe/ZnS quantum ...

McConnachie, LisaA; White, Collin C;Botta, Dianne;Zadworny, MeganE; Cox, David P;Beyer, R ...

P30ES007033,T32ES007032

Nanotoxicology(2013 Mar)

22264017

2013

Identifying safer anti-wear triarylphosphate additives for jet enginelubricants.

Baker, Paul E;Cole, Toby B;Cartwright, Megan;Suzuki, StephanieM; Thummel,Kenneth E; Lin, ...

P30ES007033,P42ES004696,T32ES007032

Chem BiolInteract (2013Mar 25)

23085349

2013

Merkel polyomavirus-specific T cellsfluctuate with merkel cell carcinomaburden and express therape ...

Afanasiev, Olga K;Yelistratova, Lola;Miller, Natalie;Nagase, Kotaro;Paulson, Kelly;Iyer, ...

T32ES007032 Clin Cancer Res(2013 Oct 01)

23922299

2013

Molecular mechanisms underlyinggenotype-dependent responses to dietaryrestriction.

Schleit, Jennifer;Johnson, Simon C;Bennett,Christopher F;Simko, Marissa;Trongtham, Natalie...

T32ES007032 Aging Cell (2013Dec)

23837470

2013

mTOR inhibition alleviates mitochondrialdisease in a mouse model of Leighsyndrome.

Johnson, Simon C;Yanos, Melana E;Kayser,Ernst-Bernhard;Quintana, Albert;Sangesland, Maya;...

T32ES007032 Science (2013Dec 20)

24231806

2013

Preparation of rodent testis co-cultures. Wegner, Susanna;Hong, Sungwoo;Yu, Xiaozhong;Faustman, ElaineM

P30ES007033,T32ES007032

Curr ProtocToxicol (2013Feb)

23408194

2013

Stress profiling of longevity mutantsidentifies Afg3 as a mitochondrialdeterminant of cytoplasmic ...

Delaney, Joe R;Ahmed, Umema;Chou, Annie; Sim,Sylvia; Carr,Daniel; Murakami,Christopher J; ...

T32ES007032 Aging Cell (2013Feb)

23167605

2013

Sulforaphane is not an effective antagonistof the human pregnane X-receptor in vivo.

Poulton, EmmaJane; Levy, Lisa;Lampe, JohannaW; Shen, Danny D;Tracy, Julia;Shuhart, Margar ...

P30ES007033,T32ES007032

Toxicol ApplPharmacol (2013Jan 01)

23153560

2013

The glutathione synthesis gene Gclmmodulates amphiphilic polymer-coatedCdSe/ZnS quantum dot-induce ...

McConnachie, LisaA; Botta, Dianne;White, Collin C;Weldy, Chad S;Wilkerson,Hui-Wen; Yu, Ji ...

P30ES007033,T32ES007032

PLoS One (2013) 23724032

2013

Antioxidants for Alzheimer disease: arandomized clinical trial withcerebrospinal fluid biomarker m ...

Galasko, DouglasR; Peskind, Elaine;Clark, ChristopherM; Quinn, JosephF; Ringman, JohnM; Ji ...

T32ES007032 Arch Neurol(2012 Jul)

22431837

2012

Glutathione (GSH) and the GSH synthesisgene Gclm modulate vascular reactivity inmice.

Weldy, Chad S;Luttrell, Ian P;White, Collin C;Morgan-Stevenson,Vicki; Bammler,Theo K; Beye ...

P30ES007033,T32ES007032

Free Radic BiolMed (2012 Sep15)

22824862

2012

Human skeletal muscle feed arteries:evidence of regulatory potential.

Ives, S J;Andtbacka, R H I;Park, S-Y; Donato,A J; Gifford, J R;Noyes, R D;Lesniewski, L ...

T32ES007032 Acta Physiol(Oxf) (2012 Oct)

22726882

2012

In vitro toxicity assessment ofamphiphillic polymer-coated CdSe/ZnSquantum dots in two human liver ...

Smith, Wesley E;Brownell, Jessica;White, Collin C;Afsharinejad,Zahra; Tsai, Jesse;Hu, Xia ...

P30ES007033,T32ES007032

ACS Nano (2012Nov 27)

23039050

2012

Increased sensitivity to testicular toxicityof transplacental benzo[a]pyrene exposurein male gluta ...

Nakamura, BrookeN; Mohar, Isaac;Lawson, GregoryW; Cortés, MabelM; Hoang, YvonneD; Ortiz, ...

P30ES007033,T32ES007032

Toxicol Sci (2012Mar)

22253057

2012

Multiplex immunoassays of peptidehormones extracted from formalin-fixed,paraffin-embedded tissue a ...

Strathmann,Frederick G;Borlee, Grace;Born, Donald E;Gonzalez-Cuyar,Luis F; Huber,Bertrand ...

T32ES007032 Clin Chem (2012Feb)

22205691

2012

Novel antibody capture assay forparaffin-embedded tissue detectswide-ranging amyloid beta and pair ...

Postupna, Nadia;Rose, Shannon E;Bird, Thomas D;Gonzalez-Cuyar,Luis F; Sonnen,Joshua A; Lar ...

T32ES007032 Brain Pathol(2012 Jul)

21999410

2012

pH neutralization protects againstreduction in replicative lifespan followingchronological aging i ...

Murakami,Christopher;Delaney, Joe R;Chou, Annie; Carr,Daniel; Schleit,Jennifer; Sutphin,...

T32ES007032 Cell Cycle (2012Aug 15)

22871733

2012

Response to DNA damage of CHEK2missense mutations in familial breastcancer.

Roeb, Wendy;Higgins, Jake;King, Mary-Claire

T32ES007032 Hum Mol Genet(2012 Jun 15)

22419737

2012

Yeast as a model to understand theinteraction between genotype and theresponse to calorie restrict ...

Schleit, Jennifer;Wasko, Brian M;Kaeberlein, Matt

T32ES007032 FEBS Lett (2012Aug 31)

22828279

2012

Behavioral Characterization ofGCLM-Knockout Mice, a Model forEnhanced Susceptibility to Oxidative ...

Cole, Toby B;Giordano,Gennaro; Co, AilaL; Mohar, Isaac;Kavanagh,Terrance J; Costa,Lucio ...

P30ES007033,T32ES007032

J Toxicol (2011) 21559092

2011

Biomarkers of organophosphorus (OP)exposures in humans.

Marsillach, Judit;Richter, Rebecca J;Kim, Jerry H;Stevens, RichardC; MacCoss,Michael J; To ...

P42ES004696,T32ES007032

Neurotoxicology(2011 Oct)

21767566

2011

DIESEL particulate exposed macrophagesalter endothelial cell expression of eNOS,iNOS, MCP1, and gl ...

Weldy, Chad S;Wilkerson,Hui-Wen; Larson,Timothy V;Stewart, James A;Kavanagh,Terrance J

P30ES007033,T32ES007032

Toxicol In Vitro(2011 Dec)

21920430

2011

Elevated proteasome capacity extendsreplicative lifespan in Saccharomycescerevisiae.

Kruegel, Undine;Robison, Brett;Dange, Thomas;Kahlert, Günther;Delaney, Joe R;Kotireddy, S ...

T32ES007032 PLoS Genet(2011 Sep)

21931558

2011

Fluorescent assessment of intracellularcalcium in individual cells.

Cox, David P;White, Collin C;Kavanagh,Terrance J

P30ES007033,T32ES007032

Methods MolBiol (2011)

21815070

2011

Gain and loss of function for glutathionesynthesis: impact on advancedatherosclerosis in apolipopr ...

Callegari, Andrea;Liu, Yuhua; White,Collin C; Chait,Alan; Gough, Peter;Raines, Elaine W;C ...

P30ES007033,T32ES007032

ArteriosclerThromb VascBiol (2011 Nov)

21868708

2011

Heterozygosity in the glutathione synthesisgene Gclm increases sensitivity to dieselexhaust partic ...

Weldy, Chad S;White, Collin C;Wilkerson,Hui-Wen; Larson,Timothy V;Stewart, James A;Gill, ...

P30ES007033,T32ES007032

Inhal Toxicol(2011 Oct)

21967497

2011

JNK3-mediated apoptotic cell death inprimary dopaminergic neurons.

Choi, Won-Seok;Klintworth,Heather M; Xia,Zhengui

T32ES007032 Methods MolBiol (2011)

21815073

2011

Measurements of astrocyte proliferation. Guizzetti, Marina;Kavanagh,Terrance J; Costa,Lucio G

P30ES007033,T32ES007032


21815078

2011

Mitochondrial therapeutics in Alzheimer'sdisease and Parkinson's disease.

Hoekstra, Jake G;Montine, KathleenS; Zhang, Jing;Montine, Thomas J

T32ES007032 Alzheimers ResTher (2011)

21722346

2011

Muscarinic receptor-activated signaltransduction pathways involved in theneuritogenic effect of as ...

Guizzetti, Marina;Moore, Nadia H;VanDeMark,Kathryn L;Giordano,Gennaro; Costa,Lucio G

P30ES007033,T32ES007032

Eur J Pharmacol(2011 Jun 1)

21453700

2011

Proteomic analysis ofacetaminophen-induced changes inmitochondrial protein expression usingspectr ...

Stamper, BrendanD; Mohar, Isaac;Kavanagh,Terrance J; Nelson,Sidney D

P30ES007033,T32ES007032

Chem ResToxicol (2011Apr 18)

21329376

2011

Reduced transcript expression of genesaffected by inherited and de novo CNVs inautism.

Nord, Alex S;Roeb, Wendy;Dickel, Diane E;Walsh, Tom;Kusenda, Mary;O'Connor, KristenLewis ...

T32ES007032,T32ES015459

Eur J Hum Genet(2011 Jun)

21448237

2011

Role of cerebrospinal fluid and plasmabiomarkers in the diagnosis ofneurodegenerative disorders an ...

Gonzalez-Cuyar,Luis F; Sonnen,Joshua A; Montine,Kathleen S; Keene,C Dirk; Montine,Thomas J

T32ES007032 Curr NeurolNeurosci Rep(2011 Oct)

21725901

2011

Roles of DNA polymerase I in leading andlagging-strand replication defined by ahigh-resolution mut ...

Allen, Jennifer M;Simcha, David M;Ericson, Nolan G;Alexander, DavidL; Marquette,Jacob T; V ...

T32ES007032 Nucleic AcidsRes (2011 Sep 1)

21622658

2011

Sir2 deletion prevents lifespan extensionin 32 long-lived mutants.

Delaney, Joe R;Sutphin, George L;Dulken, Ben; Sim,Sylvia; Kim, Jin R;Robison, Brett;Schle ...

T32ES007032 Aging Cell (2011Dec)

21902802

2011

The MDT-15 subunit of mediator interactswith dietary restriction to modulatelongevity and fluorant ...

Schleit, Jennifer;Wall, Valerie Z;Simko, Marissa;Kaeberlein, Matt

T32ES007032 PLoS One (2011) 22132200

2011

Toll-like receptor 4 and myeloiddifferentiation factor 88 providemechanistic insights into the cau ...

Vaquero, Javier;Campbell, Jean S;Haque, Jamil;McMahan, Ryan S;Riehle, Kimberly J;Bauer, R ...

T32ES007032 Hepatology (2011Aug)

21574169

2011

Transcriptional impact oforganophosphate and metal mixtures onolfaction: copper dominates the chlo ...

Tilton, Fred A;Tilton, Susan C;Bammler, Theo K;Beyer, Richard P;Stapleton, PatriciaL; Scho ...

P30ES007033,P42ES004696,T32ES007032

Aquat Toxicol(2011 Apr)

21356183

2011

A systems-based approach to investigatedose- and time-dependentmethylmercury-induced gene expressi ...

Robinson, JoshuaF; Guerrette,Zachariah; Yu,Xiaozhong; Hong,Sungwoo;Faustman, ElaineM

P30ES007033,T32ES007032

Birth Defects ResB Dev ReprodToxicol (2010Jun)

20540155

2010

Attenuated progression of diet-inducedsteatohepatitis in glutathione-deficientmice.

Haque, Jamil A;McMahan, Ryan S;Campbell, Jean S;Shimizu-Albergine,Masami; Wilson,Angela M; ...

P30ES007033,T32ES007032

Lab Invest (2010Dec)

20548286

2010

Ethanol inhibits neuritogenesis induced byastrocyte muscarinic receptors.

Guizzetti, Marina;Moore, Nadia H;Giordano,Gennaro;VanDeMark,Kathryn L; Costa,

P30ES007033,T32ES007032

Glia (2010 Sep) 20648635

2010

Lucio G Genomic duplication and overexpressionof TJP2/ZO-2 leads to altered expressionof apoptosis genes i ...

Walsh, Tom;Pierce, Sarah B;Lenz, Danielle R;Brownstein,Zippora;Dagan-Rosenfeld,Orit; Shah ...

T32ES007032,T32ES015459

Am J Hum Genet(2010 Jul 09)

20602916

2010

Integrating genetic and toxicogenomicinformation for determining underlyingsusceptibility to devel ...

Robinson, JoshuaF; Port, Jesse A;Yu, Xiaozhong;Faustman, ElaineM

P30ES007033,T32ES007032

Birth Defects ResA Clin MolTeratol (2010Oct)

20706997

2010

JNK3 mediates paraquat- androtenone-induced dopaminergic neurondeath.

Choi, Won-Seok;Abel, Glen;Klintworth,Heather; Flavell,Richard A; Xia,Zhengui

T32ES007032 J NeuropatholExp Neurol (2010May)

20418776

2010

Nonsteroidal anti-inflammatory drugs areassociated with increased neuritic plaques.

Sonnen, J A;Larson, E B;Walker, R L;Haneuse, S; Crane,P K; Gray, S L;Breitner, J C S; Mo...

T32ES007032 Neurology (2010Sep 28)

20811000

2010

Rapid activation of glutamate cysteineligase following oxidative stress.

Krejsa, Cecile M;Franklin,Christopher C;White, Collin C;Ledbetter, JeffreyA; Schieven, Gar ...

P30ES007033,P42ES004696,T32ES007032

J Biol Chem(2010 May 21)

20332089

2010

Ethanol inhibits muscarinicreceptor-induced axonal growth in rathippocampal neurons.

VanDemark,Kathryn L;Guizzetti, Marina;Giordano,Gennaro; Costa,Lucio G

P30ES007033,T32ES007032

Alcohol Clin ExpRes (2009 Nov)

19673741

2009

Gene expression profiles in zebrafish brainafter acute exposure to domoic acid atsymptomatic and a ...

Lefebvre, Kathi A;Tilton, Susan C;Bammler, Theo K;Beyer, Richard P;Srinouanprachan,Sengkeo ...

P30ES007033,P42ES004696,T32ES007032


18936300

2009

Glutamate cysteine ligase (GCL)transgenic and gene-targeted mice forcontrolling glutathione synthe ...

Mohar, Isaac;Botta, Dianne;White, Collin C;McConnachie, LisaA; Kavanagh,Terrance J

T32ES007032 Curr ProtocToxicol (2009Feb)

23045016

2009

Glutamate, excitotoxicity, andprogrammed cell death in Parkinsondisease.

Caudle, WMichael; Zhang,Jing

T32ES007032 Exp Neurol (2009Dec)

19815009

2009

Homocysteine stimulates antioxidantresponse element-mediated expression ofglutamate-cysteine ligas ...

Bea, Florian;Hudson, FrancescaN; Neff-Laford,Haley; White,Collin C;Kavanagh,Terrance J; K ...

P30ES007033,T32ES007032

Atherosclerosis(2009 Mar)

18691715

2009

In vitro hepatic metabolism of2,2',4,4',5-pentabromodiphenyl ether(BDE 99) in Chinook salmon (Onch ...

Browne, Eva P;Stapleton, HeatherM; Kelly, ShannonM; Tilton, Susan C;Gallagher, Evan P

P42ES004696,T32ES007032

Aquat Toxicol(2009 May 17)

19346012

2009

Manganese inhibits the ability ofastrocytes to promote neuronaldifferentiation.

Giordano,Gennaro; Pizzurro,Daniella;VanDeMark,Kathryn; Guizzetti,Marina; Costa,Lucio G

P30ES007033,T32ES007032

Toxicol ApplPharmacol (2009Oct 15)

19524604

2009

Modulation of microglial innate immunityin Alzheimer's disease by activation ofperoxisome prolifer ...

Shie, Feng-Shiun;Nivison, Mary;Hsu, Pei-Chien;Montine, Thomas J

T32ES007032 Curr Med Chem(2009)

19199928

2009

Nonmotor symptoms of Parkinson'sdisease revealed in an animal model withreduced monoamine storage ...

Taylor, Tonya N;Caudle, WMichael; Shepherd,Kennie R; Noorian,AliReza; Jackson,Chad R; Iuvo ...

T32ES007032,T32ES012870

J Neurosci (2009Jun 24)

19553450

2009

Protection of hippocampal neurogenesisfrom toll-like receptor 4-dependent innateimmune activation ...

Keene, C Dirk;Chang, Rubens;Stephen, Christina;Nivison, Mary;Nutt, Samuel E;Look, Amy; Br ...

T32ES007032 Am J Pathol(2009 Jun)

19389932

2009

Relationships between deficits in tissuemass and transcriptional programs afterpartial hepatectomy ...

Li, Jiangning;Campbell, Jean S;Mitchell, Claudia;McMahan, Ryan S;Yu, Xuesong;Riehle, Kimb ...

T32ES007032 Am J Pathol(2009 Sep)

19700759

2009

Rotenone and paraquat do not directlyactivate microglia or induce inflammatorycytokine release.

Klintworth,Heather; Garden,Gwenn; Xia,Zhengui

P30ES007033,T32ES007032

Neurosci Lett(2009 Oct 2)

19559752

2009

Structure, function, and post-translationalregulation of the catalytic and modifiersubunits of glu ...

Franklin,Christopher C;Backos, Donald S;Mohar, Isaac;White, Collin C;Forman, Henry J;Kava ...

P30ES007033,P42ES004696,T32ES007032

Mol Aspects Med(2009 Feb-Apr)

18812186

2009

The activation of M1 muscarinic receptorsignaling induces neuronal differentiationin pyramidal hip ...

VanDeMark,Kathryn L;Guizzetti, Marina;Giordano,Gennaro; Costa,Lucio G

P30ES007033,T32ES007032

J Pharmacol ExpTher (2009 May)

19190235

2009

The atrophy and changes in the cellularcompositions of the thymus and spleenobserved in mice subje ...

Qazi, MousumiRahman; Xia,Zhenlei;Bogdanska, Jasna;Chang, Shu-Ching;Ehresman, Dave J;Buten ...

T32ES007032 Toxicology (2009Jun 16)

19464571

2009

Computational models of ethanol-inducedneurodevelopmental toxicity acrossspecies: Implications for ...

Gohlke, Julia M;Griffith, WilliamC; Faustman,Elaine M

T32ES007032 Birth Defects ResB Dev ReprodToxicol (2008Feb)

18161053

2008

Engineered recombinant humanparaoxonase 1 (rHuPON1) purified fromEscherichia coli protects against ...

Stevens, RichardC; Suzuki,Stephanie M; Cole,Toby B; Park,Sarah S; Richter,Rebecca J; Furlo ...

P30ES007033,P42ES004696,T32ES007032

Proc Natl AcadSci U S A (2008Sep 2)

18711144

2008

Gene expression profiling analysis revealsarsenic-induced cell cycle arrest andapoptosis in p53-pr ...

Yu, Xiaozhong;Robinson, JoshuaF; Gribble,Elizabeth; Hong,Sung Woo; Sidhu,Jaspreet S; Faust ...

P30ES007033,T32ES007032

Toxicol ApplPharmacol (2008Dec 15)

18929588

2008

Hepatic expression profiling in smoltingand adult coho salmon (Onchorhynchuskisutch).

Gallagher, Evan P;LaVire, Helene M;Bammler, Theo K;Stapleton, PatriciaL; Beyer, RichardP; ...

P30ES007033,P42ES004696,T32ES007032

Environ Res(2008 Mar)

18241857

2008

Modulating GSH synthesis usingglutamate cysteine ligase transgenic andgene-targeted mice.

Botta, Dianne;White, Collin C;Vliet-Gregg,Portia; Mohar,Isaac; Shi, Shengli;McGrath, Moni ...

P30ES007033,P42ES004696,T32ES007032

Drug Metab Rev(2008)

18642143

2008

Sensitivity of mouse lung fibroblastsheterozygous for GPx4 to oxidative stress.

Garry, Michael R;Kavanagh,Terrance J;Faustman, ElaineM; Sidhu, JaspreetS; Liao, Reiling; W...

T32ES007032 Free Radic BiolMed (2008 Mar15)

18206984

2008

Transcriptional biomarkers andmechanisms of copper-induced olfactoryinjury in zebrafish.

Tilton, Fred; Tilton,Susan C; Bammler,Theo K; Beyer,Richard; Farin,Frederico;Stapleton, P ...

P30ES007033,P42ES004696,T32ES007032

Environ SciTechnol (2008Dec 15)

19174923

2008

CAR2 displays unique ligand binding andRXRalpha heterodimerizationcharacteristics.

Auerbach, Scott S;Dekeyser, JoshuaG; Stoner, MatthewA; Omiecinski,Curtis J

T32ES007032 Drug MetabDispos (2007Mar)

17194715

2007

Glutamate cysteine ligase modifier subunitdeficiency and gender as determinants ofacetaminophen-in ...

McConnachie, LisaA; Mohar, Isaac;Hudson, FrancescaN; Ware, Carol B;Ladiges, Warren C;Ferna ...

P30ES007033,P42ES004696,T32ES007032

Toxicol Sci (2007Oct)

17584759

2007

Multicenter study of acetaminophenhepatotoxicity reveals the importance ofbiological endpoints in ...

Beyer, Richard P;Fry, Rebecca C;Lasarev, MichaelR; McConnachie,Lisa A; Meira,Lisiane B; Pa ...

T32ES007032 Toxicol Sci (2007Sep)

17562736

2007

5' and 3' region variability in the dopaminetransporter gene (SLC6A3), pesticideexposure and Parki ...

Kelada, Samir N P;Checkoway,Harvey; Kardia,Sharon L R;Carlson,Christopher S;Costa-Mallen, ...

P30ES007033,P42ES004696,T32ES007032

Hum Mol Genet(2006 Oct 15)

16963468

2006

Chronic beryllium disease and glutathionebiosynthesis genes.

Bekris, Lynn M;Viernes,Hannah-Malia A;Farin, Federico M;Maier, Lisa A;Kavanagh,Terrance J ...

P30ES007033,P42ES004696,T32ES007032

J Occup EnvironMed (2006 Jun)

16766924

2006

Neurotoxicity of domoic Acid incerebellar granule neurons in a geneticmodel of glutathione deficie ...

Giordano, G;White, C C;McConnachie, L A;Fernandez, C;Kavanagh, T J;Costa, L G

P30ES007033,P42ES004696,T32ES007032

Mol Pharmacol(2006 Dec)

17000861

2006

p38 MAP kinase mediates apoptosisthrough phosphorylation of BimEL atSer-65.

Cai, Beibei; Chang,Sandra H; Becker,Esther B E; Bonni,Azad; Xia, Zhengui

T32ES007032 J Biol Chem(2006 Sep 01)

16818494

2006

Werner Syndrome, aging and cancer. Ozgenc, A; Loeb, LA

T32ES007032 Genome Dyn(2006)

18724062

2006

A systems-based computational model fordose-response comparisons of two modeof action hypotheses f ...

Gohlke, J M;Griffith, W C;Faustman, E M

P30ES007033,T32ES007032

Toxicol Sci (2005Aug)

15917484

2005

Characterization of the in vitrotranscriptional activity of polymorphicalleles of the human monoam ...

Costa-Mallen,Paola; Kelada,Samir N; Costa,Lucio G;Checkoway,Harvey

P30ES007033,P42ES004696,T32ES007032

Neurosci Lett(2005 Jul 22-29)

15936531

2005

Critical role of R-loops in processingreplication blocks.

Camps, Manel;Loeb, Lawrence A

T32ES007032 Front Biosci(2005 Jan 01)

15569610

2005

Dopamine transporter (SLC6A3) 5' regionhaplotypes significantly affecttranscriptional activity in ...

Kelada, Samir N;Costa-Mallen,Paola; Checkoway,Harvey; Carlson,Christopher S;Weller, Terri- ...

P30ES007033,P42ES004696,T32ES007032

PharmacogenetGenomics (2005Sep)

16041244

2005

Hox11L1 expression by precursors ofenteric smooth muscle: an alternativeexplanation for megacecum ...

Kapur, Raj P;Clarke, ChristineM; Doggett,Barbara; Taylor,Brian E;Baldessari, Audrey;Paris ...

P30ES007033,T32ES007032

Pediatr DevPathol (2005Mar-Apr)

15803212

2005

Incorporation of reporter-labelednucleotides by DNA polymerases.

Anderson, Jon P;Angerer, Bernhard;Loeb, Lawrence A

P30ES007033,T32ES007032

Biotechniques(2005 Feb)

15727132

2005

Inhibition of RIP2/RIck/CARDIAKactivity by pyridinyl imidazole inhibitorsof p38 MAPK.

Argast, GretchenM; Fausto, Nelson;Campbell, Jean S

T32ES007032 Mol CellBiochem (2005Jan)

15724446

2005

The magnitude of methylmercury-inducedcytotoxicity and cell cycle arrest isp53-dependent.

Gribble, ElizabethJ; Hong,Sung-Woo;Faustman, ElaineM

P30ES007033,T32ES007032

Birth Defects ResA Clin MolTeratol (2005Jan)

15641097

2005

A novel role for serum response factor inneuronal survival.

Chang, Sandra H;Poser, Steve; Xia,Zhengui

T32ES007032 J Neurosci (2004Mar 03)

14999078

2004

DNA sequence analysis of monoamineoxidase B gene coding and promoterregions in Parkinson's disease ...

Costa-Mallen,Paola;Afsharinejad,Zahra; Kelada,Samir N; Costa,Lucio G; Franklin,Gary M; Sw ...

P30ES007033,P42ES004696,T32ES007032

Mov Disord(2004 Jan)

14743364

2004

Effect of methylmercury onglutamate-cysteine ligase expression in theplacenta and yolk sac during ...

Diaz, Dolores;Krejsa, Cecile M;White, Collin C;Charleston, Jay S;Kavanagh,Terrance J

P30ES007033,P42ES004696,T32ES007032

Reprod Toxicol(2004 Nov)

15336720

2004

Epidermal growth factor receptortransactivation mediates tumor necrosisfactor-induced hepatocyte r ...

Argast, GretchenM; Campbell, JeanS; Brooling, JohnT; Fausto, Nelson

T32ES007032 J Biol Chem(2004 Aug 13)

15199050

2004

Glutamate-cysteine ligase attenuatesTNF-induced mitochondrial injury andapoptosis.

Botta, Dianne;Franklin,Christopher C;White, Collin C;Krejsa, Cecile M;Dabrowski,Michael J ...

P30ES007033,P42ES004696,T32ES007032

Free Radic BiolMed (2004 Sep 1)

15288121

2004

Nuclear factor kappaB activity determinesthe sensitivity of kidney epithelial cells toapoptosis: i ...

Dieguez-Acuña,Francisco J; Polk,William W; Ellis,Maureen E;Simmonds, PLynne; Kushleika,Jo ...

P30ES007033,P42ES004696,T32ES007032

Toxicol Sci (2004Nov)

15282405

2004

Rotenone-induced apoptosis is mediatedby p38 and JNK MAP kinases in humandopaminergic SH-SY5Y cell ...

Newhouse,Kathleen; Hsuan,Shih-Ling; Chang,Sandra H; Cai,Beibei; Wang,Yupeng; Xia,Zhengui

T32ES007032 Toxicol Sci (2004May)

14976342

2004

The role of cell death during neocorticalneurogenesis and synaptogenesis:implications from a compu ...

Gohlke, Julia M;Griffith, WilliamC; Faustman,Elaine M

P30ES007033,T32ES007032

Brain Res DevBrain Res (2004Jul 19)

15246691

2004

Viral error catastrophe by mutagenicnucleosides.

Anderson, Jon P;Daifuku, Richard;Loeb, Lawrence A

P30ES007033,T32ES007032

Annu RevMicrobiol (2004)

15487935

2004

When pol I goes into high gear: processiveDNA synthesis by pol I in the cell.


T32ES007032 Cell Cycle (2004Feb)

14712068

2004

Alternatively spliced isoforms of thehuman constitutive androstane receptor.

Auerbach, Scott S;Ramsden, Richard;Stoner, Matthew A;Verlinde,Christophe;Hassett, Christop ...

P30ES007033,T32ES007032

Nucleic AcidsRes (2003 Jun 15)

12799447

2003

Fluorescence-based microtiter plate assayfor glutamate-cysteine ligase activity.

White, Collin C;Viernes, Hannah;Krejsa, Cecile M;Botta, Dianne;Kavanagh,Terrance J

P30ES007033,P42ES004696,T32ES007032

Anal Biochem(2003 Jul 15)

12814619

2003

Genetic background modifies intestinalpseudo-obstruction and the expression of areporter gene in H ...

Parisi, Melissa A;Baldessari, AudreyE; Iida, Malissa HK; Clarke,Christine M;Doggett, Barba ...

P30ES007033,T32ES007032

Gastroenterology(2003 Nov)

14598259

2003

Glutathione S-transferase M1, T1, and P1polymorphisms and Parkinson's disease.

Kelada, Samir N;Stapleton, PatriciaL; Farin, FedericoM; Bammler, TheoK; Eaton, David L;Smi ...

P30ES007033,P42ES004696,T32ES007032

Neurosci Lett(2003 Jan 30)

12524158

2003

Paraoxonase 1 promoter and coding regionpolymorphisms in Parkinson's disease.

Kelada, S N;Costa-Mallen, P;Checkoway, H;Viernes, H A;Farin, F M;Smith-Weller, T;Frankli ...

P30ES007033,P42ES004696,T32ES007032

J NeurolNeurosurgPsychiatry (2003Apr)

12640090

2003

Targeted gene evolution in Escherichiacoli using a highly error-prone DNApolymerase I.

Camps, Manel;Naukkarinen, Jussi;Johnson, Ben P;Loeb, Lawrence A

T32ES007032 Proc Natl AcadSci U S A (2003Aug 19)

12909725

2003

Targeted mutagenesis in E. coli: Apowerful tool for the generation of randommutant libraries.


T32ES007032 Discov Med(2003 Oct)

20704859

2003

Use of Pol I-deficient E. coli for functionalcomplementation of DNA polymerase.


T32ES007032 Methods MolBiol (2003)

12824565

2003

Attenuation of nuclear factor kappa B(NF-kappaB) promotes apoptosis ofkidney epithelial cells: a p ...

Woods, James S;Dieguez-Acuña,Francisco J; Ellis,Maureen E;Kushleika, John;Simmonds, P Lynn...

P30ES007033,P42ES004696,T32ES007032

Environ HealthPerspect (2002Oct)

12426138

2002

Caspase-3-Dependent Cleavage of theGlutamate-L-Cysteine Ligase CatalyticSubunit during Apoptotic C ...

Franklin,Christopher C;Krejsa, Cecile M;Pierce, Robert H;White, Collin C;Fausto, Nelson; K...

P30ES007033,P42ES004696,T32ES007032

Am J Pathol(2002 May)

12000740

2002

Expression of glutamate-cysteine ligaseduring mouse development.

Diaz, Dolores;Krejsa, Cecile M;Kavanagh,Terrance J

P30ES007033,P42ES004696,T32ES007032

Mol Reprod Dev(2002 May)

11933164

2002

Expression of human microsomal epoxidehydrolase in Saccharomyces cerevisiaereveals a functional ro ...

Kelly, Edward J;Erickson, KristinE; Sengstag,Christian; Eaton,David L

P30ES007033,T32ES007032


11752683

2002

Gender difference in the interaction ofsmoking and monoamine oxidase B intron13 genotype in Parkin ...

Kelada, Samir N;Costa-Mallen,Paola; Costa, LucioG; Smith-Weller,Terry; Franklin,Gary M; Sw ...

P30ES007033,P42ES004696,T32ES007032


12428723

2002

In vitro production and screening of DNApolymerase eta mutants for catalyticdiversity.

Glick, Eitan;Anderson, Jon P;Loeb, Lawrence A

P30ES007033,T32ES007032

Biotechniques(2002 Nov)

12449395

2002

Investigations of methylmercury-inducedalterations in neurogenesis.

Faustman, ElaineM; Ponce, RafaelA; Ou, Ying C;Mendoza, MaAileen C;Lewandowski,Thomas; Kav ...

P30ES007033,T32ES007032


12426147

2002

Analysis of mitochondria by flowcytometry.

T32ES007032 Methods CellBiol (2001)

11070835

2001

Applied molecular evolution ofO6-benzylguanine-resistant DNAalkyltransferases in human hematopoiet ...

Davis, B M;Encell, L P;Zielske, S P;Christians, F C;Liu, L; Friebert, SE; Loeb, L A; Ger...

T32ES007032 Proc Natl AcadSci U S A (2001Apr 24)

11296271

2001

Expression of suppressors of cytokinesignaling during liver regeneration.

Campbell, J S;Prichard, L;Schaper, F;Schmitz, J;Stephenson-Famy,A; Rosenfeld, M E;Argast ...

T32ES007032 J Clin Invest(2001 May)

11375418

2001

HPLC-based assays for enzymes ofglutathione biosynthesis.

White, C C; Krejsa,C J; Eaton, D L;Kavanagh, T J

P30ES007033,P42ES004696,T32ES007032

Curr ProtocToxicol (2001)

23045057

2001

Localization of glutamate-cysteine ligasemRNA and protein in mouse kidney andinduction with methyl ...

Díaz, D; Krejsa, CM; Kavanagh, T J

P30ES007033,P42ES004696,T32ES007032

Toxicol Lett(2001 Aug 06)

11514103

2001

Mercuric ion attenuates nuclearfactor-kappaB activation and DNAbinding in normal rat kidney epithe ...

Dieguez-Acuña, FJ; Ellis, M E;Kushleika, J;Woods, J S

P30ES007033,P42ES004696,T32ES007032

Toxicol ApplPharmacol (2001Jun 15)

11437639

2001

Taxol induces apoptosis in corticalneurons by a mechanism independent ofBcl-2 phosphorylation.

Figueroa-Masot, XA; Hetman, M;Higgins, M J;Kokot, N; Xia, Z

T32ES007032 J Neurosci (2001Jul 01)

11425893

2001

Tissue specific changes in the expressionof glutamate-cysteine ligase mRNAs inmice exposed to meth ...

Díaz, D; Krejsa, CM; White, C C;Keener, C L; Farin,F M; Kavanagh, TJ

P30ES007033,P42ES004696,T32ES007032

Toxicol Lett(2001 Jun 20)

11439218

2001

Baculovirus vectors repressphenobarbital-mediated gene inductionand stimulate cytokine expression ...

Beck, N B; Sidhu, JS; Omiecinski, C J

P30ES007033,T32ES007032

Gene Ther (2000Aug)

10918498

2000

Detection of oxidative stress inlymphocytes usingdichlorodihydrofluorescein diacetate.

Krejsa, C M;Schieven, G L

P42ES004696,T32ES007032


10909075

2000

Disruption of redox homeostasis in tumornecrosis factor-induced apoptosis in amurine hepatocyte ce ...

Pierce, R H;Campbell, J S;Stephenson, A B;Franklin, C C;Chaisson, M; Poot,M; Kavanagh, T ...

T32ES007032 Am J Pathol(2000 Jul)

10880392

2000

Effect of phenylalanine and its metaboliteson the proliferation and viability ofneuronal and astro ...

Oberdoerster, J;Guizzetti, M;Costa, L G

P30ES007033,T32ES007032

J Pharmacol ExpTher (2000 Oct)

10991993

2000

Enhanced in vivo repair ofO(4)-methylthymine by a mutant humanDNA alkyltransferase.

Encell, L P; Loeb,L A

T32ES007032 Carcinogenesis(2000 Jul)

10874019

2000

Modulation of glutathione andglutamate-L-cysteine ligase bymethylmercury during mousedevelopment.

Thompson, S A;White, C C; Krejsa,C M; Eaton, D L;Kavanagh, T J

P30ES007033,P42ES004696,T32ES007032

Toxicol Sci (2000Sep)

10966520

2000

Catalytic activity and quantitation ofcytochrome P-450 2E1 in prenatal humanbrain.

Brzezinski, M R;Boutelet-Bochan,H; Person, R E;Fantel, A G;Juchau, M R

T32ES007032 J Pharmacol ExpTher (1999 Jun)

10336564

1999

Detection of changes in mitochondrialfunction during apoptosis by simultaneousstaining with multip ...

Poot, M; Pierce, RH

T32ES007032 Cytometry (1999Apr 1)

10213196

1999

Human O(6)-alkylguanine-DNAalkyltransferase: protection againstalkylating agents and sensitization ...

Abril, N;Luque-Romero, FL; Christians, F C;Encell, L P; Loeb,L A; Pueyo, C

T32ES007032 Carcinogenesis(1999 Nov)

10545410

1999

Improving enzymes for cancer genetherapy.

Encell, L P; Landis,D M; Loeb, L A

T32ES007032 Nat Biotechnol(1999 Feb)

10052349

1999

Induction of glutamate-cysteine ligase(gamma-glutamylcysteine synthetase) inthe brains of adult fe ...

Thompson, S A;White, C C; Krejsa,C M; Diaz, D;Woods, J S; Eaton,D L; Kavanagh, T J

P30ES007033,P42ES004696,T32ES007032

Toxicol Lett(1999 Oct 29)

10593589

1999

Inhibition of human prenatal biosynthesisof all-trans-retinoic acid by ethanol,ethanol metabolites ...

Khalighi, M;Brzezinski, M R;Chen, H; Juchau,M R

T32ES007032 BiochemPharmacol (1999Apr 01)

10075087

1999

Lack of modulation by phenobarbital ofcyclic AMP levels or protein kinase Aactivity in rat primary ...

Beck, N B;Omiecinski, C J

T32ES007032 BiochemPharmacol (1999Oct 01)

10484068

1999

Redesigning the substrate specificity ofhuman O(6)-alkylguanine-DNAalkyltransferase. Mutants with ...

Encell, L P; Loeb,L A

T32ES007032 Biochemistry(1999 Sep 14)

10508414

1999

The role of intracellular glutathione inmethylmercury-induced toxicity inembryonic neuronal cells.

Ou, Y C; White, CC; Krejsa, C M;Ponce, R A;Kavanagh, T J;Faustman, E M

P30ES007033,P42ES004696,T32ES007032


10591515

1999

Cyclopamine-induced holoprosencephalyand associated craniofacial malformationsin the golden hamste ...

Coventry, S;Kapur, R P;Siebert, J R

T32ES007032 Pediatr DevPathol (1998Jan-Feb)

10463269

1998

Cytochrome-P450-dependentbiotransformation of xenobiotics in humanand rodent embryonic tissues.

Juchau, M R;Boutelet-Bochan,H; Huang, Y

T32ES007032 Drug Metab Rev(1998 Aug)

9710705 1998

Effects of chemical inducers on humanmicrosomal epoxide hydrolase in primaryhepatocyte cultures.

Hassett, C;Laurenzana, E M;Sidhu, J S;Omiecinski, C J

T32ES007032 BiochemPharmacol (1998Apr 01)

9605429 1998

Effects of O6-benzylguanine on growthand differentiation of P19 embryoniccarcinoma cells treated w ...

Seeley, M R;Faustman, E M

T32ES007032 Teratog CarcinogMutagen (1998)

9728795 1998

Engineering human DNAalkyltransferases for gene therapy usingrandom sequence mutagenesis.

Encell, L P; Coates,M M; Loeb, L A

T32ES007032 Cancer Res (1998Mar 1)

9500464 1998

Evaluation of P19 cells for studyingmechanisms of developmental toxicity:application to four direc ...


T32ES007032 Toxicology (1998May 15)

9699793 1998

I-PpoI and I-CreI homing site sequencedegeneracy determined by randommutagenesis and sequential in ...

Argast, G M;Stephens, K M;Emond, M J;Monnat Jr, R J

T32ES007032 J Mol Biol (1998Jul 17)

9665841 1998

Identification of amino acid residuesessential for high aflatoxin B1-8,9-epoxideconjugation activi ...

Van Ness, K P;McHugh, T E;Bammler, T K;Eaton, D L

P30ES007033,T32ES007032

Toxicol ApplPharmacol (1998Sep)

9772212 1998

Impact of oxidative stress on signaltransduction control by phosphotyrosinephosphatases.

Krejsa, C M;Schieven, G L

P42ES004696,T32ES007032


9788895 1998

Inhibition of embryonic retinoic acidsynthesis by aldehydes of lipidperoxidation and prevention of ...

Chen, H; Juchau,M R

T32ES007032 Free Radic BiolMed (1998 Feb)

9438553 1998

Biotransformation of all-trans-retinal,13-cis-retinal, and 9-cis-retinal catalyzedby conceptal cyt ...

Chen, H; Juchau,M R

T32ES007032 BiochemPharmacol (1997Mar 21)

9113107 1997

Chemical teratogenesis in humans:biochemical and molecular mechanisms.

Juchau, M R T32ES007032 Prog Drug Res(1997)

9388384 1997

Crystallization and preliminary X-raystudies of I-PpoI: a nuclear,intron-encoded homing endonuclea ...

Flick, K E;McHugh, D;Heath, J D;Stephens, K M;Monnat Jr, R J;Stoddard, B L

T32ES007032 Protein Sci (1997Dec)

9416623 1997

Expression of CYP2E1 duringembryogenesis and fetogenesis in humancephalic tissues: implications fo ...

Boutelet-Bochan,H; Huang, Y;Juchau, M R

T32ES007032 Biochem BiophysRes Commun(1997 Sep 18)

9299528 1997

Genetic analysis of the Chlamydomonasreinhardtii I-CreI mobile intron homingsystem in Escherichia ...

Seligman, L M;Stephens, K M;Savage, J H;Monnat Jr, R J

T32ES007032 Genetics (1997Dec)

9409828 1997

Glutathione S-transferases act asisomerases in isomerization of13-cis-retinoic acid to all-trans-r ...

Chen, H; Juchau,M R

T32ES007032 Biochem J (1997Nov 01)

9581548 1997

Sensitization of olfactory guanylyl cyclaseto a specific imprinted odorant in cohosalmon.

Dittman, A H;Quinn, T P; Nevitt,G A; Hacker, B;Storm, D R

T32ES007032 Neuron (1997Aug)

9292727 1997

A biologically-based dose-response modelfor developmental toxicology.

Leroux, B G;Leisenring, W M;Moolgavkar, S H;Faustman, E M

T32ES007032 Risk Anal (1996Aug)

8819338 1996

Changes in the number of astrocytes andmicroglia in the thalamus of the monkeyMacaca fascicularis ...

Charleston, J S;Body, R L;Bolender, R P;Mottet, N K;Vahter, M E;Burbacher, T M

T32ES007032 Neurotoxicology(1996)

8784824 1996

Effects of ethanol on biotransformation ofall-trans-retinol and all-trans-retinal toall-trans-reti ...

Chen, H;Namkung, M J;Juchau, M R

T32ES007032 Alcohol Clin ExpRes (1996 Aug)

8865972 1996

Effects of organophosphate exposure onmuscarinic acetylcholine receptor subtypemRNA levels in the ...

Yagle, K; Costa, LG

P30ES007033,P42ES004696,T32ES007032

Neurotoxicology(1996)

8856746 1996

Interactive dysmorphogenic effects ofall-trans-retinol and ethanol on culturedwhole rat embryos du ...

Chen, H; Yang, HY; Namkung, M J;Juchau, M R

T32ES007032 Teratology (1996Jul)

8916365 1996

Localization by in situ hybridization ofgamma-glutamylcysteine synthetasemRNA expression in rat ki ...

Li, S; Thompson, SA; Kavanagh, T J;Woods, J S

P30ES007033,P42ES004696,T32ES007032

Toxicol ApplPharmacol (1996Nov)

8917676 1996

Localization of gamma-glutamylcysteinesynthetase mRNA expression in mousebrain following methylmer ...

Li, S; Thompson, SA; Woods, J S

P30ES007033,P42ES004696,T32ES007032

Toxicol ApplPharmacol (1996Sep)

8806884 1996

Promoter region analysis of the ratCYP2B1 and CYP2B2 genes.

Sommer, K M;Ramsden, R; Sidhu,J; Costa, P;Omiecinski, C J

T32ES007032 Pharmacogenetics(1996 Aug)

8873225 1996

Autometallographic determination ofinorganic mercury distribution in thecortex of the calcarine su ...

Charleston, J S;Body, R L; Mottet,N K; Vahter, M E;Burbacher, T M

T32ES007032 Toxicol ApplPharmacol (1995Jun)

7785060 1995

Biotransformation of all-trans-retinol andall-trans-retinal to all-trans-retinoic acid inrat conce ...

Chen, H;Namkung, M J;Juchau, M R

T32ES007032 BiochemPharmacol (1995Oct 12)

7488242 1995

Demethylation of methyl mercury indifferent brain sites of Macaca fascicularismonkeys during long- ...

Vahter, M E;Mottet, N K;Friberg, L T; Lind,S B; Charleston, JS; Burbacher, T M

T32ES007032 Toxicol ApplPharmacol (1995Oct)

7570604 1995

In vitro biotransformation of aflatoxin B1(AFB1) in channel catfish liver.

Gallagher, E P;Eaton, D L

T32ES007032 Toxicol ApplPharmacol (1995May)

7747288 1995

Modulation of nitrosourea toxicity inrodent embryonic cells byO6-benzylguanine, a depletor of O6-m ...

Kidney, J K;Faustman, E M

T32ES007032 Toxicol ApplPharmacol (1995Jul)

7597698 1995

Toxicity of four alkylating agents on invitro rat embryo differentiation anddevelopment.


T32ES007032 Fundam ApplToxicol (1995Jun)

7657057 1995

Benzene and benzene metabolites asembryotoxic agents: effects on cultured ratembryos.

Chapman, D E;Namkung, M J;Juchau, M R

T32ES007032 Toxicol ApplPharmacol (1994Sep)

8079346 1994

Dysmorphogenic effects of nitric oxide(NO) and NO-synthase inhibition: studieswith intra-amniotic ...

Lee, Q P; Juchau,M R

T32ES007032 Teratology (1994Jun)

7538231 1994

Embryogenesis in cultured whole ratembryos after combined exposures to3,3',5-triiodo-L-thyronine ( ...

Kraft, J C;Willhite, C C;Juchau, M R

T32ES007032 J Craniofac GenetDev Biol (1994Apr-Jun)

8071425 1994

Evidence for a peripheral olfactorymemory in imprinted salmon.

Nevitt, G A;Dittman, A H;Quinn, T P; MoodyJr, W J

T32ES007032 Proc Natl AcadSci U S A (1994May 10)

7514302 1994

Increases in the number of reactive glia inthe visual cortex of Macaca fascicularisfollowing subcl ...

Charleston, J S;Bolender, R P;Mottet, N K; Body,R L; Vahter, M E;Burbacher, T M

T32ES007032 Toxicol ApplPharmacol (1994Dec)

7992310 1994

9-cis-retinoic acid: a direct-actingdysmorphogen.

Kraft, J C; Juchau,M R

T32ES007032 BiochemPharmacol (1993Aug 17)

8363644 1993

Characterization of cytoskeletal andneuronal markers in micromass cultures ofrat embryonic midbrai ...

Whittaker, S G;Wroble, J T;Silbernagel, S M;Faustman, E M

T32ES007032 Cell Biol Toxicol(1993 Oct-Dec)

8039012 1993

Chemical teratogenesis. Juchau, M R T32ES007032 Prog Drug Res(1993)

8108564 1993

Redox activities of mercury-thiolcomplexes: implications formercury-induced porphyria and toxicity ...

Miller, D M;Woods, J S

P42ES004696,T32ES007032

Chem BiolInteract (1993 Jul)

8330322 1993

Software for counting cells and estimatingstructural volumes with the opticaldisector and fraction ...

Bolender, R P;Charleston, J S

T32ES007032 Microsc Res Tech(1993 Jul 01)

8358082 1993

Tissue levels of retinoids in humanembryos/fetuses.

Kraft, J C;Shepard, T;Juchau, M R

T32ES007032 Reprod Toxicol(1993)

8448410 1993

2-Aminopurine overrides multiple cellcycle checkpoints in BHK cells.

Andreassen, P R;Margolis, R L

T32ES007032 Proc Natl AcadSci U S A (1992Mar 15)

1549593 1992

Chi enhances heteroduplex DNA levelsduring recombination.

Holbeck, S L;Smith, G R

T32ES007032 Genetics (1992Dec)

1459441 1992

Conceptual biotransformation of4-oxo-all-trans-retinoic acid,4-oxo-13-cis-retinoic acid and all-tr ...

Creech Kraft, J;Juchau, M R

T32ES007032 BiochemPharmacol (1992May 28)

1599515 1992

Correlations between conceptalconcentrations of all-trans-retinoic acidand dysmorphogenesis after ...

Kraft, J C; Juchau,M R

T32ES007032 Drug MetabDispos (1992Mar-Apr)

1352213 1992

Effects of benzimidazole analogs oncultures of differentiating rodentembryonic cells.

Whittaker, S G;Faustman, E M

T32ES007032 Toxicol ApplPharmacol (1992Mar)

1553749 1992

Embryotoxic action of methyl mercury oncoho salmon embryos.

Devlin, E W;Mottet, N K

T32ES007032 Bull EnvironContam Toxicol(1992 Sep)

1498484 1992

Mechanisms of glucagon-inducedincreases in rates of cytochromeP450-dependent pentoxyphenoxazone O-...

Lee, Q P; Juchau,M R


1337707 1992

Microinjections of cultured ratconceptuses: studies with4-oxo-all-trans-retinoic acid, 4-oxo-13-ci...

Kraft, J C; Bechter,R; Lee, Q P;Juchau, M R

T32ES007032 Teratology (1992Mar)

1631780 1992

Bioactivation of aflatoxin B1 by humanliver microsomes: role of cytochromeP450 IIIA enzymes.

Ramsdell, H S;Parkinson, A;Eddy, A C; Eaton,D L

P42ES004696,T32ES007032

Toxicol ApplPharmacol (1991May)

1902334 1991

cAMP-dependent regulation ofP450-catalyzed dealkylation in ratconceptal tissues.

Lee, Q P; Yang, HY; Namkung, M J;Juchau, M R


1725761 1991

Characterization of a CMPNeuAc:lactosylceramide alpha2----3sialyltransferase from rainbow trouthe ...

Ostrander, G K;Holmes, E H

T32ES007032 Comp BiochemPhysiol B (1991)

2060283 1991

Effects of albendazole and albendazolesulfoxide on cultures of differentiatingrodent embryonic cel ...

Whittaker, S G;Faustman, E M

T32ES007032 Toxicol ApplPharmacol (1991Jun 01)

2038752 1991

Elevated levels of all-trans-retinoic acid incultured rat embryos 1.5 hr afterintraamniotic microi ...

Kraft, J C; Bui, T;Juchau, M R

T32ES007032 BiochemPharmacol (1991Nov 27)

1764110 1991

Induction of partial mitosis in BHK cellsby 2-aminopurine.

Andreassen, P R;Margolis, R L

T32ES007032 J Cell Sci (1991Oct)

1757489 1991

Isolation and characterization of the majorglycosphingolipids from the liver of therainbow trout ( ...

Ostrander, G K;Bozlee, M;Fukuda, M; Dell,A; Thomas-Oates,J E; Levery, S B;Eaton, H L; Ha ...

T32ES007032 Arch BiochemBiophys (1991Feb 01)

1989525 1991

Mercury-induced H2O2 production andlipid peroxidation in vitro in rat kidneymitochondria.

Lund, B O; Miller,D M; Woods, J S

P42ES004696,T32ES007032

BiochemPharmacol (1991Dec 11)

1768276 1991

Microinjection of cultured rat embryos:studies with retinol, 13-cis- andall-trans-retinoic acid.

Lee, Q P; Juchau,M R; Kraft, J C

T32ES007032 Teratology (1991Sep)

1948766 1991

Reactivity of Hg(II) with superoxide:evidence for the catalytic dismutation ofsuperoxide by Hg(II) ...

Miller, D M; Lund,B O; Woods, J S

P42ES004696,T32ES007032

J BiochemToxicol (1991)

1663557 1991

A flow cytometric comparison of DNAcontent and glutathione levels inhepatocytes of English sole (P ...

Jenner, N K;Ostrander, G K;Kavanagh, T J;Livesey, J C; Shen,M W; Kim, S C;Holmes, E H

T32ES007032 Arch EnvironContam Toxicol(1990 Nov-Dec)

2256702 1990

Biochemical and immunochemicalanalysis of rat brain dynamin interactionwith microtubules and organ ...

Scaife, R;Margolis, R L

T32ES007032 J Cell Biol (1990Dec)

2148566 1990

Chemically induced growth inhibition andcell cycle perturbations in cultures ofdifferentiating rod ...

Ribeiro, P L;Faustman, E M


1694600 1990

Dysmorphogenesis elicited bymicroinjected acetaminophen analogs andmetabolites in rat embryos cult ...

Stark, K L; Lee, QP; Namkung, M J;Harris, C; Juchau,M R

T32ES007032 J Pharmacol ExpTher (1990 Oct)

2213573 1990

Methylmercury developmentalneurotoxicity: a comparison of effects inhumans and animals.

Burbacher, T M;Rodier, P M;Weiss, B

P30ES001247,T32ES007032

NeurotoxicolTeratol (1990May-Jun)

2196419 1990

Mouse liver glutathione S-transferaseisoenzyme activity toward aflatoxinB1-8,9-epoxide and benzo[a ...

Ramsdell, H S;Eaton, D L

P42ES004696,T32ES007032

Toxicol ApplPharmacol (1990Sep 01)

2120795 1990

Role of spermatozoal platelet-activatingfactor in fertilization.

Kuzan, F B;Geissler, F T;Henderson Jr, W R

T32ES007032 Prostaglandins(1990 Jan)

2155438 1990

Sequence and gene expression of rabbitcytochrome P450 IIC16: comparison tohighly related family me ...

Hassett, C;Omiecinski, C J

P42ES004696,T32ES007032

Nucleic AcidsRes (1990 Mar25)

2326187 1990

Species susceptibility to aflatoxin B1carcinogenesis: comparative kinetics ofmicrosomal biotransfo ...


T32ES007032 Cancer Res (1990Feb 1)

2105159 1990

Analysis of methyl mercury binding siteson tubulin subunits and microtubules.

Vogel, D G;Margolis, R L;Mottet, N K

T32ES007032 PharmacolToxicol (1989Feb)

2755920 1989

Bioactivation in chemical teratogenesis. Juchau, M R T32ES007032 Annu RevPharmacolToxicol (1989)

2658769 1989

Diagnosis of early pregnancy byultrasound in Macaca fascicularis.

Conrad, S H;Sackett, G P;Burbacher, T M

T32ES007032 J Med Primatol(1989)

2654401 1989

Human nasal epithelium: characterizationand effects of in vitro exposure to sulfurdioxide.

McManus, M S;Altman, L C;Koenig, J Q;Luchtel, D L;Covert, D S;Virant, F S; Baker,C

T32ES007032 Exp Lung Res(1989 Dec)

2693085 1989

Isolation and characterization of ratcytochrome P-450IIB gene familymembers. Use of the polymerase ...

Giachelli, C M;Lin-Jones, J;Omiecinski, C J

P42ES004696,T32ES007032

J Biol Chem(1989 Apr 25)

2708353 1989

Kinetics of methyl mercury in blood andbrain during chronic exposure in themonkey Macaca fascicula ...

Stinson, C H;Shen, D M;Burbacher, T M;Mohamed, M K;Mottet, N K

T32ES007032 PharmacolToxicol (1989Sep)

2813296 1989

Lipid mediator production bypost-implantation rat embryos in vitro.

Geissler, F T;Kuzan, F B;Faustman, E M;Henderson Jr, W R

T32ES007032 Prostaglandins(1989 Aug)

2505333 1989

Behavioral and biochemical effects ofpostnatal parathion exposure in the rat.

Stamper, C R;Balduini, W;Murphy, S D;Costa, L G

T32ES007032 NeurotoxicolTeratol (1988May-Jun)

3211105 1988

Coordinate accumulation of fivetranscripts in the primary mesenchymeduring skeletogenesis in the s ...

Harkey, M A;Whiteley, H R;Whiteley, A H

T32ES007032 Dev Biol (1988Feb)

2892749 1988

Developmental toxicity of aflatoxin B1 inthe rodent embryo in vitro: contribution ofexogenous biot ...

Geissler, F;Faustman, E M

T32ES007032 Teratology (1988Feb)

3127910 1988

Effects of modulation of hepaticglutathione on biotransformation andcovalent binding of aflatoxin ...

Monroe, D H;Eaton, D L


3131927 1988

Identification of a novel dihydroxymetabolite of aflatoxin B1 produced invitro and in vivo in rats ...

Eaton, D L;Monroe, D H;Bellamy, G;Kalman, D A

T32ES007032 Chem ResToxicol (1988Mar-Apr)

2979717 1988

Inhibition of v-fms-induced tumor growthin nude mice by castanospermine.

Ostrander, G K;Scribner, N K;Rohrschneider, L R

T32ES007032 Cancer Res (1988Mar 01)

3124955 1988

Modification of aflatoxin B1biotransformation in vitro and DNAbinding in vivo by dietary broccoli ...


T32ES007032 J Toxicol EnvironHealth (1988)

3141626 1988

Advantages of using aquatic animals forbiomedical research on reproductivetoxicology.

Mottet, N K;Landolt, M L

T32ES007032 Environ HealthPerspect (1987Apr)

3297666 1987

Biologic variables in the hair uptake ofmethylmercury from blood in the macaquemonkey.

Mottet, N K; Body,R L; Wilkens, V;Burbacher, T M

T32ES007032 Environ Res(1987 Apr)

3569185 1987

Comparative effects of butylatedhydroxyanisole on hepatic in vivo DNAbinding and in vitro biotrans ...

Monroe, D H;Eaton, D L

T32ES007032 Toxicol ApplPharmacol (1987Sep 30)

3116723 1987

Effects of phenobarbital on the biliaryexcretion of aflatoxin P1-glucuronide andaflatoxin B1-S-glu ...

Holeski, C J;Eaton, D L;Monroe, D H;Bellamy, G M

T32ES007032 Xenobiotica(1987 Feb)

3105186 1987

Methylmercury effects on reproductionand offspring size at birth.

Burbacher, T M;Mohamed, M K;Mottett, N K

T32ES007032 Reprod Toxicol(1987-1988)

2980392 1987

Pancreatic neoplasia induced by rasexpression in acinar cells of transgenicmice.

Quaife, C J;Pinkert, C A;Ornitz, D M;Palmiter, R D;Brinster, R L

T32ES007032 Cell (1987 Mar27)

3470144 1987

Regulation of intracellular glutathione inrat embryos and visceral yolk sacs and itseffect on 2-ni ...

Harris, C;Namkung, M J;Juchau, M R

T32ES007032 Toxicol ApplPharmacol (1987Mar 30)

3564029 1987

The rat elastase I regulatory element is anenhancer that directs correct cellspecificity and devel ...

Hammer, R E;Swift, G H; Ornitz,D M; Quaife, C J;Palmiter, R D;Brinster, R L;MacDonald, R ...

T32ES007032 Mol Cell Biol(1987 Aug)

3670302 1987

Carbon monoxide inhibitsmonooxygenation by the conceptus andembryotoxic effects of proteratogens i ...

Faustman-Watts, EM; Giachelli, C M;Juchau, M R

T32ES007032 Toxicol ApplPharmacol (1986May)

3705078 1986

Effects of methylmercury on themorphogenesis of the rat cerebellum.

Howard, J D;Mottet, N K

T32ES007032 Teratology (1986Aug)

3764782 1986

Effects of single-dose and repeated-dosepretreatment with2(3)-tert-butyl-4-hydroxyanisole (BHA)on ...

Monroe, D H;Holeski, C J;Eaton, D L

T32ES007032 Food ChemToxicol (1986Dec)

3100404 1986

Glucocorticoid regulation ofmetallothionein during murinedevelopment.

Quaife, C;Hammer, R E;Mottet, N K;Palmiter, R D

T32ES007032 Dev Biol (1986Dec)

3792622 1986

Methylmercury effects on cell cyclekinetics.

Vogel, D G;Rabinovitch, P S;Mottet, N K

T32ES007032 Cell Tissue Kinet(1986 Mar)

3698080 1986

Valproate hydroxylation by human fetaltissues and embryotoxicity of metabolites.

Rettie, A E;Rettenmeier, A W;Beyer, B K;Baillie, T A;Juchau, M R

T32ES007032 Clin PharmacolTher (1986 Aug)

3089669 1986

Health risks from increases inmethylmercury exposure.

Mottet, N K; Shaw,C M; Burbacher, TM

T32ES007032 Environ HealthPerspect (1985Nov)

3908085 1985

The effects of methyl mercury binding tomicrotubules.

Vogel, D G;Margolis, R L;Mottet, N K

T32ES007032 Toxicol ApplPharmacol (1985Sep 30)

4035699 1985

Cadmium hypersusceptibility in the C3Hmouse liver: cell specificity and possiblerole of metallothi ...

Quaife, C; Durnam,D; Mottet, N K

T32ES007032 Toxicol ApplPharmacol (1984Oct)

6484995 1984

Methylmercury exposure and reproductivedysfunction in the nonhuman primate.

Burbacher, T M;Monnett, C; Grant,K S; Mottet, N K

T32ES007032 Toxicol ApplPharmacol (1984Aug)

6464019 1984

Sister chromatid exchange analysis incultured peripheral blood leukocytes of thecoldwater marine f ...

Zakour, H R;Landolt, M L;Kocan, R M

T32ES007032 Basic Life Sci(1984)

6529413 1984

Taxol-induced bundling of brain-derivedmicrotubules.

Turner, P F;Margolis, R L

T32ES007032 J Cell Biol (1984Sep)

6147357 1984

Arsenic-induced exencephaly in the mouseand associated lesions occurring duringneurulation.

Morrissey, R E;Mottet, N K

T32ES007032 Teratology (1983Dec)

6665738 1983

Neovascular responses induced bycultured aortic endothelial cells.

Harris-Hooker, SA; Gajdusek, C M;Wight, T N;Schwartz, S M

T32ES007032 J Cell Physiol(1983 Mar)

6187756 1983

Neural tube defects and brain anomalies: areview of selected teratogens and theirpossible modes of ...

Monissey, R E;Mottet, N K

T32ES007032 Neurotoxicology(1981 Jan)

15622731

1981

Modulation of monooxygenase activitiesby hematin and 7,8-benzoflavone in fetaltissues of rats, rab ...

Omiecinski, C J;Chao, S T; Juchau,M R

T32ES007032 Dev PharmacolTher (1980)

7438968 1980

project title: environmental pathology/toxicology … · michael t p30es007033, t32es007032 part...

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