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Protein Synthesis $100 $200 $300 $400 $500 $100 $ 100 $100 $100 $200 $200 $200 $200 $300 $300 $300 $300 $400 $400 $400 $400 $500 $500 $500 $500 Central Dogma Basics Transcripti on RNA Mutations FINAL ROUND Translation

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Page 1: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Protein Synthesis

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Central Dogma Basics Transcription RNA Mutations

FINAL ROUND

Translation

Page 2: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics:

$100 Question

This is the place where transcription takes place in eukaryotic cells

BACK TO GAME

ANSWER

Page 3: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics :

$100 Answer

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Nucleus

Page 4: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics :

$200 Question

BACK TO GAME

ANSWER

These are the parts of mRNA that do not code for protein

Page 5: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics:

$200 Answer

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introns

Page 6: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics :

$300 Question

BACK TO GAME

ANSWER

This is the site where translation takes place

Page 7: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics :

$300 Answer

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Ribosomes (in cytoplasm or on Rough ER)

Page 8: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics:

$400 Question

BACK TO GAME

ANSWER

This is a sequence of DNA that codes for protein(s)

Page 9: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics :

$400 Answer

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Gene

Page 10: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics :

$500 Question

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ANSWER

This is the central dogma

Page 11: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Central Dogma Basics :

$500 Answer

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DNA RNA Protein

Page 12: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription:

$100 Question

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ANSWER

This is the enzyme that synthesizes mRNA

Page 13: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$100 Answer

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RNA polymerase

Page 14: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$200 Question

BACK TO GAME

ANSWER

This is the region of DNA where RNA polymerase binds

Page 15: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$200 Answer

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Promotor

Page 16: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$300 Question

BACK TO GAME

ANSWER

This is the portion of DNA that signals transcription to stop

Page 17: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription:

$300 Answer

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Terminator

Page 18: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$400 Question

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ANSWER

This is the process takes place after transcription in which mRNA is edited

Page 19: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$400 Answer

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mRNA splicing

Page 20: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$500 Question

How does mRNA exit the nucleus

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ANSWER

Page 21: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Transcription :

$500 Answer

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Through nuclear pores

Page 22: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation:

$100 Question

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ANSWER

This is the start codon

Page 23: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation:

$100 Answer

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AUG

Page 24: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :

$200 Question

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ANSWER

This is the site on the ribosomes in which polypeptide chain grows

Page 25: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :

$200 Answer

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P site

Page 26: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :

$300 Question

BACK TO GAME

ANSWER

These are the type of bonds that exist between amino acids

Page 27: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :

$300 Answer

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peptide bonds

Page 28: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :

$400 Question

BACK TO GAME

ANSWER

This is the site on the ribosome in which the next tRNA enters the ribosome

Page 29: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :

$400 Answer

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A site

Page 30: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation:500

BACK TO GAME

ANSWER

Describe initiation of translation

Page 31: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :500

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mRNA finds a ribosome and binds to it; the start codon (AUG) codes for a tRNA carrying the amino acid methionine; this tRNA enters the ribosome at the P site and translation begins

Page 32: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA:

$100 Question

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ANSWER

This type of RNA contains codons

Page 33: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA:

$100 Answer

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mRNA

Page 34: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA:

$200 Question

BACK TO GAME

ANSWER

This type of RNA contains anti-codons

Page 35: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Translation :

$200 Answer

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tRNA

Page 36: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA :

$300 Question

BACK TO GAME

ANSWER

This type of RNA carries amino acids

Page 37: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA: $300 Answer

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tRNA

Page 38: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA:

$400 Question

BACK TO GAME

ANSWER

RNA is different from DNA because…..

Page 39: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA:

$400 Answer

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Ribose sugar; Uracil instead of Thymine; single stranded

Page 40: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA: $500 Question

BACK TO GAME

ANSWER

These are the types of RNA involved in translation

Page 41: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

RNA: $500 Answer

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mRNA, tRNA, rRNA

Page 42: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutations:

$100 Question

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ANSWER

This type of mutation codes for the same amino acid therefore there is no effect on the protein

Page 43: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation:

$100 Answer

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Silent mutation

Page 44: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation :

$200 Question

BACK TO GAME

ANSWER

This type of mutation involves a substitution of a nucleotide that results in a stop codon reached to soon therefore the polypeptide chain is not complete and the protein is nonfunctional

Page 45: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation : $200 Answer

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Nonsense mutation

Page 46: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation :

$300 Question

BACK TO GAME

ANSWER

Insertion or deletion of a nucleotide will result in this type of mutation

Page 47: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation : $300 Answer

BACK TO GAME

Frameshift

Page 48: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation:

$400 Question

BACK TO GAME

ANSWER

This type of mutation is a substitution which results in a different amino acid

Page 49: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation :

$400 Answer

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Missense mutation

Page 50: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation :

$500 Question

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ANSWER

Why can one difference in amino acid sequence be harmful?

Page 51: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

Mutation :

$500 Answer

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The protein shape can be altered by just one change in amino acid; if the shape is incorrect the function of the protein is incorrect

Page 52: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

FINAL ROUND Question

BACK TO GAME

ANSWER

Transcribe and Translate the following gene….

5’ TTTCAGCTACAAAGAGTAGATT 3’

Page 53: Protein Synthesis $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Central Dogma Basics Transcription RNA Mutations FINAL ROUND Translation

FINAL ROUND Question

BACK TO GAME

ANSWER

DNA= 5’TTTCAGCTACAAAGAGTAGATT 3’

mRNA=3’AAAGUCAUGUUUCUCAUCUAA 5’

Amino acids= (start)met- phe- leu- iso- stop


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APPLAUSE 23456 100 300 100 200 100 300 200 300 400 500 400 500 400 100 300 200 500 400 100 300 200 500 400 100 300 200 500 400 200 1 3

1 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500

$100 $400 $300$200$400 $200$100$100$400 $200$200$500 $500$300 $200$500 $100$300$100$300 $500$300$400$400$500

$100 $100 $100 $100 $500 $500 $500 $500 $200 $200 $200 $200 $300 300 $300 300 $300 300 $300 300 $400 400 $400 400 $400 $400 $400 $400 $500 500 $500

$100$200$100$300$100$200 $400 $200$200$400 $100$400$100$400 $500 $200$500 $300$500$300$300$500$300$400 $500

JEOPARDY Reconstruction Categories 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400

100 400 100 200 300 400 100 200 300 400 100 200 300 400 100 200 300 400 200 300 History People constitution Tradition Misc. FR

200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 celuilequel

EarthquakesReview $100 $100 $200 $200 $300 $300 $400 $400 $500 $500 $100 $100 $200 $200 $300 $300 $400 $400 $500 $500 $100 $100 $200 $200 $300 $300 $400

100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500

Transformations SymmetryAsymptotesFunctionsSketching 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400

Ruins & artifacts Misc. 100 300 100 200 100 300 200 300 400 500 400 500 400 100 300 200 500 400 100 300 200 500 400 100 300 200 500 400 200 LocationCulture

$100 $200 $300 $400 $100 $200 $300 $400 $100 $200 $300 $400 $100 $200 $300 $400 $100 $200 $300 $400

100 200 300 400 100 200 300 400 100 200 300 400 100 200 300 400 Final Jeopardy! * 100 200 300 400

Jeopardy $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500

$100$200$100$300$100$200 $400 $200$200$400 $100 $400 $100$400 $500 $200$500 $300$500$300$300$500$300$400 $500

Trivia $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100

` $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200

BritainU.S.FrancePeopleVocab 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500

$100 $200 $300 $400 $500 $400 $300 $200 $100 $500 $400 $300 $200 $100 $500 $400 $300 $200 $100 $500 $400 $300 $200 $100 $200 $300 $400 $500

JEOPARDY Economics Categories 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500

$ 200 200 $ 300 300 $ 400 400 $ 500 500 $ 100 $ 200 200 $ 300 300 $ 400 400 $ 500 500 $ 100 100 $ 200 200 $ 300 300 $ 400 400 $ 500 500 $ 100 100 $ 200

$100 $400 $300 $200 $400 $200 $100$100 $400 $200$200 $500$500 $300 $200 $500 $100 $300 $100 $300 $500 $300 $400$400 $500

200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 BebidasFrutasVegetalesCarnesMisc. 100

Parabolas $100 100 $300 $300 $200 200 $400 400 $500 500 $100 100 $300 300 $200 200 $400 400 $500 500 $100 100 $300 300 $200 200 $400 400 $500 500 $100

$100€¦ · $100 $400 $300 $200 $400 $200 $100 $100 $400 $200 $200 $500 $500 $300 $200 $500 $100 $300 $100 $300 $500 $300 $400 $400 $500

Proteins $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100

$100 $400 $300 $200 $400 $200 $100$100 $400 $200$200 $500 $500 500 $300 300 $200 200 $500 $100 100 $300 $100 $300 $500 $300 $400 400 $400 $500

Moody Mathematics $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400

MatterWaterpHBonding Miscellaneous 100 200 300 400 100 200 300 400 200 300 400 200 300 400 100

Alex $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200

GeographyCultureDynastiesVocabularyReligion 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500

$100 $400 $300$200 $400 400 $200$100$100$400 $200$200$500 $500$300 $200$500 $100$300$100$300 $500$300$400$400$500

200 300 400 500 Europe & Geography 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100