Prävention - Epidemiologie

Bruno Ledergerber USZ

HIV-CUP CROI Boston, 3.-6. März 2014

PrEP: Pharmacology Insights (#61) Craig W. Hendrix

17.3.14, HIV-CUP CROI 14 (Boston)

Implementing PrEP in Resource Constrained Settings (#61) Nelly R. Mugo

17.3.14, HIV-CUP CROI 14 (Boston)

Implementing PrEP in Resource Constrained Settings (#61) Nelly R. Mugo

17.3.14, HIV-CUP CROI 14 (Boston)

GSK1265744 Nanosuspension to prevent rectal SHIV transmission in Macaques (#39) Chasity D. Andrews

17.3.14, HIV-CUP CROI 14 (Boston)

GSK1265744 Nanosuspension to prevent rectal SHIV transmission in Macaques (#39) Chasity D. Andrews

17.3.14, HIV-CUP CROI 14 (Boston)

Monthly GSK744 Injections protect Macaques against repeated vaginal SHIV exposures (#40LB) Jessica Radzio

17.3.14, HIV-CUP CROI 14 (Boston)

Transmission Risk if HIV+ Partner is on Suppre-ssive ART: PARTNER Study (#153LB) A. Rodger

17.3.14, HIV-CUP CROI 14 (Boston)

(CYFU: Condomless sex Years of Follow-Up)

17.3.14, HIV-CUP CROI 14 (Boston)

Transmission Risk if HIV+ Partner is on Suppre-ssive ART: PARTNER Study (#153LB) A. Rodger

No Difference in Incidence of Myocardial Infarction for HIV+ and HIV- Individuals in Recent Years (#737) Daniel B. Klein

• 24‘768 HIV+ and 257‘600 HIV- patients (91% male) from Kaiser-Permanente California 1996-2011

• Matched 1:10 by age, sex, enrollment, center • Poisson regression adjusted for age, sex, year,

census-based socioeconomic status, race/ethnicity, hypertension, smoking, diabetes, alcohol/drug abuse, overweight/obesity, and lipid-lowering therapy

17.3.14, HIV-CUP CROI 14 (Boston)

No Difference in Incidence of Myocardial Infarction for HIV+ and HIV- Individuals in Recent Years (#737) Daniel B. Klein

17.3.14, HIV-CUP CROI 14 (Boston)

No Difference in Incidence of Myocardial Infarction for HIV+ and HIV- Individuals in Recent Years (#737) Daniel B. Klein

17.3.14, HIV-CUP CROI 14 (Boston)

HIV Infection and Immunodeficiency as Risk Factors for Ischemic Stroke (#741) Julia L. Marcus

17.3.14, HIV-CUP CROI 14 (Boston)

HIV Infection and Immunodeficiency as Risk Factors for Ischemic Stroke (#741) Julia L. Marcus

17.3.14, HIV-CUP CROI 14 (Boston)

HIV Infection and the Risk of Cardiovascular Disease in Women (#734) Julie A. Womack

• 710 HIV+ and 1480 HIV- women from VACS 2003-2009

• Unmatched • Cox proportional hazards models adjusted for age,

race/ethnicity, lipids, smoking, blood pressure, diabetes, renal disease, obesity, hepatitis C, and substance use/abuse.

17.3.14, HIV-CUP CROI 14 (Boston)

HIV Infection and the Risk of Cardiovascular Disease in Women (#734) Julie A. Womack

17.3.14, HIV-CUP CROI 14 (Boston)

Is there continued evidence for an association between abacavir and myocardial infarction risk? (#747) Caroline A. Sabin

17.3.14, HIV-CUP CROI 14 (Boston)

• D:A:D Study with over 49‘000 patients from 11 cohorts in Europe, USA and Australia

• Comparing period pre-March 2008 with post-March 2008 when the initial results of increased MI risk for patients on ABC were published

• Poisson regression analyses

Is there continued evidence for an association between abacavir and myocardial infarction risk? (#747) Caroline A. Sabin

17.3.14, HIV-CUP CROI 14 (Boston)

Is there continued evidence for an association between abacavir and myocardial infarction risk? (#747) Caroline A. Sabin

17.3.14, HIV-CUP CROI 14 (Boston)