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Radiation Protection in Radiotherapy Part 10 Good Practice in EBT Lecture 1 (cont.): Equipment design IAEA Training Material on Radiation Protection in Radiotherapy

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IAEA Training Material on Radiation Protection in Radiotherapy. Radiation Protection in Radiotherapy. Part 10 Good Practice in EBT Lecture 1 (cont.): Equipment design. 2. Features of safe design in practice. A General considerations B Kilovoltage radiation units C Telecurie units - PowerPoint PPT Presentation

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Page 1: Radiation Protection in Radiotherapy

Radiation Protection inRadiotherapy

Part 10

Good Practice in EBT

Lecture 1 (cont.): Equipment design

IAEA Training Material on Radiation Protection in Radiotherapy

Page 2: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 2Radiation Protection in Radiotherapy

2. Features of safe design in practice

A General considerations

B Kilovoltage radiation units

C Telecurie units

D Megavoltage units

E Other irradiation units

Page 3: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 3Radiation Protection in Radiotherapy

A. General Safety Requirements

• Radiation Protection Measures include• Protection of the patient during treatment

• Equipment shielding

• Collimation system

• Patient comfort and control

• Protection of others• Room shielding (this was covered in part 7)

Page 4: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 4Radiation Protection in Radiotherapy

Equipment shielding

• Part of dose reduction strategy for patients

• Dose to patient other than target due to scatter and leakage

Page 5: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 5Radiation Protection in Radiotherapy

Equipment shielding

• X Ray equipment - only needed when machine is on• protects the patient during treatment

• Telecobalt units - shielding needed all the time• protects patient and staff during set-up

General design limit - leakage should be lessthan 0.1% of the primary radiation

Page 6: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 6Radiation Protection in Radiotherapy

Testing of shielding integrity of a linac head using film

About 2t of lead

Page 7: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 7Radiation Protection in Radiotherapy

Collimation

• Creates outlines of the radiation field which should conform to the target

• Can be done by a variety of different measures depending on the treatment unit type

• Always includes some leakage through the collimation - typically <2% of the primary beam

Page 8: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 8Radiation Protection in Radiotherapy

Collimation

• Aim to limit field to the target only

Customized blocksor prefabricated blocksin geometric shapes

Page 9: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 9Radiation Protection in Radiotherapy

Collimation

• Applicators • electron beams

• superficial beams

• Movable jaws

• Lead blocks• fixed shapes

• customized

• Multileaf collimator

Page 10: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 10Radiation Protection in Radiotherapy

Custom shielding may reduce the dose to critical organs

• e.g. scrotal shields to reduce dose to scrotum due to scattered radiation

Page 11: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 11Radiation Protection in Radiotherapy

Patient comfort and control

• The best collimation does not help if the patient is not stable• need good immobilization devices

• need to put patient in a reasonably comfortable position (this is often difficult with very sick patients)

• need to make them feel comfortable

Page 12: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 12Radiation Protection in Radiotherapy

Immobilization/set-up devices

• There are innumerable systems - many of them home built and designed

• A good mould room is essential - they are responsible for both,• immobilization and

• block making

Page 13: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 13Radiation Protection in Radiotherapy

Immobilization/set-up devices

• Head rests

Page 14: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 14Radiation Protection in Radiotherapy

Head and Neck Immobilization

All MedTec

Head rests to fit

Prone head rest

Page 15: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 15Radiation Protection in Radiotherapy

Lateral Head position

Page 16: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 16Radiation Protection in Radiotherapy

Immobilization/set-up devices

• The more accuracy is required, the more effort one must make e.g.:

• Stereotactic head frame with repositioning accuracy better than 2mm

Page 17: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 17Radiation Protection in Radiotherapy

Immobilization/set-up devices

• Immobilization shells for head

• Vacuum bag for body immobilization

Page 18: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 18Radiation Protection in Radiotherapy

Various body immobilisation devices

All MedTec

Body fix with external markers for set-up

Page 19: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 19Radiation Protection in Radiotherapy

Belly board for prone position

• Allows ‘belly’ to move into space

• Some of the bowel can be moved out of the field

Page 20: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 20Radiation Protection in Radiotherapy

Vacuum bags

All MedTec

Customized for every patient

Page 21: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 21Radiation Protection in Radiotherapy

Immobilization/set-up devices

• Board for set-up of breast patients

Arm rest to get arm out of the treatment field

Slope to straighten sternum in order to minimize lung dose

Leg rest

Head rest

Page 22: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 22Radiation Protection in Radiotherapy

… sometimes movement is difficult to control...

• e.g. rectal and bladder filling in prostate treatment • determine location of the prostate prior to each

treatment fraction using ultrasound

Page 23: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 23Radiation Protection in Radiotherapy

… sometimes movement is difficult to control...

• e.g. lung motion due to breathing• determine motion and

gate radiation beam

External markers on the patient which can be

tracked by a video system

Page 24: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 24Radiation Protection in Radiotherapy

Low cost solutions

• Ask patients to• hold still

• have reproducible bladder filling (e.g. always full or always empty)

• provide dietary advise

• breath shallow

• Make patients feel comfortable and secure

Page 25: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 25Radiation Protection in Radiotherapy

A note on intercom systems

• Need to be able to see the patient - is he/she comfortable? Is she/he moving?

• Need to be able to talk to the patient

• Need to be able to hear if the patient is in distress

Page 26: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 26Radiation Protection in Radiotherapy

B. Kilovoltage Equipment (10 - 150 kV)

• Dose rate is approximately proportional to the nth power of the accelerating potential as kVn where 2 < n < 3

• Dose rate is approximately proportional to current (mA)

• Therefore important that kV and mA are stable.

• It is obviously important that the timer is accurate and stable

Page 27: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 27Radiation Protection in Radiotherapy

Kilovoltage Equipment (10 – 150 kV)

• Dose control is achieved by a dual timer system as it is usually not practical to use a transmission ionization chamber

• Interlocks should be present to prevent incorrect combinations of kV, mA, and filtration

Page 28: Radiation Protection in Radiotherapy

Quick Question

What are the fluctuations of the mains voltage in your hospital? What would be the consequence in dose if these would not be filtered out before generating the

high voltage for the X Ray tube?

Page 29: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 29Radiation Protection in Radiotherapy

Answer

• A +/- 10% voltage variation is not uncommon due to loading of the net at different times of the day or heavy occasional uses on the same mains (e.g. a lift)

• This translates into 40% dose variation which is unacceptable

• Mains stabilization is a MUST

Page 30: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 30Radiation Protection in Radiotherapy

Kilovoltage Equipment (10 - 150 kV)

• Leakage from the tube housing, the Air Kerma Rate (AKR) shall not exceed• 10 mGy h-1 at 1 metre from focus• 300 mGy h-1 at 5 cm from housing or accessory

equipment• if the tube is designed to operate in the range

10 - 50 kV then a special housing is required with a maximum leakage of 1 mGy h-1

• Testing for hot spots should be carried out using film-wrap techniques

Page 31: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 31Radiation Protection in Radiotherapy

Patient shielding

• May be done on the skin using lead sheets cut into customized shapes

• Special shields may be used - e.g. eye shields

Page 32: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 32Radiation Protection in Radiotherapy

Kilovoltage Equipment (150 - 400 kV)Orthovoltage irradiation units

• It is practical to use a transmission ionization chamber with this equipment and the primary dose control system should be an integrating dosemeter.

• The backup (secondary) dose control system can be either an independent integrating dosemeter or a timer

Page 33: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 33Radiation Protection in Radiotherapy

Kilovoltage Equipment (150 - 400 kV)

• Leakage from the tube housing, the Air Kerma Rate (AKR) shall not exceed• 10 mGy h-1 at 1 metre from focus

• 300 mGy h-1 at 5 cm from housing or accessory equipment (including the beam collimation system such as cones)

• Testing for hot spots should be carried out using film-wrap techniques

Page 34: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 34Radiation Protection in Radiotherapy

C. Telecurie units

• 137-Cs or more importantly 60-Co

• High activity in treatment head

• Termination of exposure is usually by dual independent timers

Page 35: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 35Radiation Protection in Radiotherapy

Timers

• Need two completely independent timers

• One should count time up, one down

Page 36: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 36Radiation Protection in Radiotherapy

Gamma-ray equipment

• The source should be sealed such that the container can withstand temperatures likely to be obtained in building fires.

• Wipe tests should be carried out initially at installation and at regular intervals to check for surface contamination. This test need not be carried out directly on the source surface and can be carried out on a surface which comes into contact with the source during normal operation of the equipment.

Page 37: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 37Radiation Protection in Radiotherapy

Cobalt unit designs

Page 38: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 38Radiation Protection in Radiotherapy

Gamma-ray equipment

• At commissioning, cross-sectional drawings of the head should be examined to identify possible locations where radiation leakage could be a problem.

• Film wrap techniques can be used to identify positions of ‘hot’ spots.

• Accurate integrated ionization chamber readings should be made at the location of any hot spots and also in a regular pattern around the head.

Page 39: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 39Radiation Protection in Radiotherapy

Gamma-ray equipment

• Leakage from the head with the source in the Off position: the Air Kerma Rate (AKR) shall not exceed• 10 Gy h-1 at 1 metre

from source

• 200 Gy h-1 at 5 cm from housing or accessory equipment

Page 40: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 40Radiation Protection in Radiotherapy

Gamma-ray equipment

• Leakage from the head with the source in the On position: the Air Kerma Rate (AKR) shall not exceed• 10 mGy h-1 at 1 metre from source or

• 0.1% of the useful beam AKR

• whichever is the greater

Page 41: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 41Radiation Protection in Radiotherapy

Gamma-ray equipment

• The beam control mechanism shall be of the ‘fail to safety’ type and will return to the Off position in the event of:• end of normal exposure• any breakdown situation• interruption of the force holding the beam

control mechanism in the On position, for example failure of electrical power or compressed air supply

Page 42: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 42Radiation Protection in Radiotherapy

Gamma-ray equipment

• In case of failure of the automatic source return section of the beam control mechanism, it shall be possible to interrupt the exposure by other means, for example, a manual return system

• It shall be possible to unload or repair the treatment head without exceeding the dose limit for occupational exposure recommended by regulation

Mechanical source position indicator

Page 43: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 43Radiation Protection in Radiotherapy

Gamma-ray equipment

• Collimation, patient immobilisation and blocking as described in first section of part 10 and the case of linacs.

• Two particularities• No commercial MLC available (but several

home built systems)

• Due to large source size and wide penumbra: penumbra trimmers (collimation close to the patient can be employed)

Page 44: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 44Radiation Protection in Radiotherapy

Specific design for Co units

• Penumbra trimmers - collimation close to patient reduces penumbra width

Page 45: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 45Radiation Protection in Radiotherapy

Beam stopper

• Metal disk at the exit side:• reduces primary beam shielding requirements• may make set-up of patients more cumbersome

Page 46: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 46Radiation Protection in Radiotherapy

D Megavoltage units

• Electron linear accelerators - linacs

• Capable of X Ray (4 to 25MV) and electron (4 to 25MeV) irradiation

Page 47: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 47Radiation Protection in Radiotherapy

Linacs

• Radiation exposure is usually controlled by two independent integrating transmission ionization chamber systems.

• One of these is designated as the primary system and should terminate the exposure at the correct number of monitor units

• The other system is termed the secondary system and is usually set to terminate the exposure after an additional dose, typically set around 0.25 Gy

• Most modern accelerators also have a timer which will terminate the exposure if both ionization chamber systems fail

Page 48: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 48Radiation Protection in Radiotherapy

Linacs

• Modern accelerators have a lot of treatment options as discussed in part 6, for example• X Rays or electrons (dual mode)• multiple energies

• 2 X Ray energies• 5 or more electron energies

• wedges• 3 or more fixed wedges• auto-wedge• dynamic wedge

Page 49: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 49Radiation Protection in Radiotherapy

Linacs

• With such a large number of possible settings it is essential that interlocks be provided to prevent inappropriate combinations from being selected

• It is also essential that the control console provide a clear indication of what functions have been set

Page 50: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 50Radiation Protection in Radiotherapy

A linac control example

Varian

Active selection

Parameter display

Page 51: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 51Radiation Protection in Radiotherapy

Linacs

• Verification systems• All accelerator manufacturers now produce

computer controlled verification systems which provide an additional check that the settings on the accelerator console are correct for• proper accelerator function and

• correspond exactly with the parameters determined for the individual patient during the treatment planning process

Page 52: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 52Radiation Protection in Radiotherapy

Linacs - a note on MLCs

• X Ray Collimators may be• rectangular (conventional)

• Multi-Leaf collimators (MLC)• the transmission through the collimators should

be less than 2% of the primary (open) beam

• The transmission between the leaves should be checked to ensure that it is less than the manufacturer’s specification - this can be done using radiographic film

Page 53: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 53Radiation Protection in Radiotherapy

Linacs - electrons

• Electron applicators, these may be• open sided for modern accelerators using double

scattering foils or scanned beams

• enclosed for older accelerators using single scattering foils

• should be checked for leakage • adjacent to the open beam

• on the sides of the applicators

Cut-out at theend of the applicator

Page 54: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 54Radiation Protection in Radiotherapy

Electron collimation

• Done at the end of the applicator using customized cut-outs

Cut-out foam where field should be

PourLMAaroundit

Page 55: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 55Radiation Protection in Radiotherapy

IEC 601.2

• Limit values at different locations around the useful field

Page 56: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 56Radiation Protection in Radiotherapy

Electron Accelerators

• Head leakage• the Air Kerma Rate (AKR) due to leakage radiation

at any point outside the maximum useful beam, but inside a plane circular area with a radius of 2 metres centred around, and perpendicular to, the central axis of the beam at the normal distance of treatment shall not exceed 0.2% of the AKR at the central axis of the open beam. The measurement shall be done with a thick shielding block covering the open beam.

Page 57: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 57Radiation Protection in Radiotherapy

Electron Accelerators

• Head leakage • Except in the area defined in the previous slide

the Air Kerma Rate (AKR) due to leakage radiation (excluding neutrons) at any point 1 metre from the path of the electrons between their origin and the target or electron window shall not exceed 0.5%

Page 58: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 58Radiation Protection in Radiotherapy

IEC standard 601.2

• Leakage in from linac head particularly of concern if the radiation can reach the patient

Page 59: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 59Radiation Protection in Radiotherapy

Guidance on leakage levelsin different parts of the field

Page 60: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 60Radiation Protection in Radiotherapy

Also consider

• Treatment in different patient positions – e.g. sitting or standing next to the linac for treatment of a hand

Page 61: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 61Radiation Protection in Radiotherapy

Linacs - a note on neutrons

• Neutrons will only be a problem if the X Ray energy is greater than 10 MV - in practice consideration MUST be given to neutrons if the energy is greater than or equal to 15MV

• The rate of equivalent dose of the neutrons should not exceed 1% of the dose-equivalent rate of the X Rays - measured in sievert

• The radiation weighting factor for the neutrons should be taken as 20. The above limit means that the neutron absorbed dose rate is always less than the X Ray absorbed dose rate

Page 62: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 62Radiation Protection in Radiotherapy

Accidents due to equipment design...

• An operator of an accelerator quickly selected X Ray mode and quickly changed to electron mode before the machine was able to complete the first request (to operate in X Ray mode) and it operated with hybrid instructions. The same accident occurred in six different hospitals and two patients died due to doses as high as about 160-180 Gy

Page 63: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 63Radiation Protection in Radiotherapy

This should not have happened...

• Contributing factors:• The computer controlled accelerators were not

tested for the extreme conditions that occurred in practice at the hospitals.

• It took too long for the manufacturer to identify the problem and disseminate the information and by then six hospitals had experienced the same failure and two patients had died from radiation

Page 64: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 64Radiation Protection in Radiotherapy

E Other irradiation units

• Diagnostic units in radiotherapy• CT scanner

• Simulator

• Other therapy irradiation units• heavy particles

Page 65: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 65Radiation Protection in Radiotherapy

Diagnostic units in radiotherapy

• Essential and often integral part of a modern radiotherapy department

• Essential for adequate target definition - therefore important also for optimization of medical exposure from a radiation protection point of view

• Includes not only X Ray equipment but may be MRI, ultrasound and nuclear medicine

• Beyond the scope of this course - however, covered in separate courses on diagnostic radiology and nuclear medicine

Page 66: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 66Radiation Protection in Radiotherapy

A note on simulators

• The simulator should be capable of reproducing all motions and X Ray exposure types (not radiation energy and dose though) of the treatment units

Page 67: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 67Radiation Protection in Radiotherapy

Simulator control

Patient clearly visible throughlarge lead glass window

Varian Medical Systems

Control screen similar to linac

Fluoroscopy screen

Page 68: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 68Radiation Protection in Radiotherapy

Simulators and other diagnostic equipment

• Often the most important aspect of design is to ensure that the simulator patient set-up can be transferred without any modifications to the treatment unit. This includes ‘imperfections’ of the systems such as couch sag under patient’s weight.

Page 69: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 69Radiation Protection in Radiotherapy

Heavy Particles

• These could include • Neutrons

• Protons

• Helium nuclei (alpha particles)

• Other heavy nuclei (Carbon nuclei)

• Negative pi mesons

• Protons are most common and increasing in their use

Page 70: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 70Radiation Protection in Radiotherapy

Heavy Particles treatment facilities

• These are very specialized installations

• shielding with high neutron fluxes can be extensive and complex

• neutrons require hydrogen rich materials for good energy absorption for example wood and or plastics

• many neutron interactions produce high energy gamma rays requiring large thicknesses of concrete , or steel to absorb them

Page 71: Radiation Protection in Radiotherapy

Part 10, lecture 1 (cont.): Equipment design 71Radiation Protection in Radiotherapy

Additional note on heavy particles

• Many of the points covered for electron accelerators are also applicable for these installations

• Specialized systems for positioning patients may be required

• The charged particle accelerators are often multipurpose facilities which also serve research objectives (e.g. material research). These applications may require entirely different beam parameters (e.g. high particle flux) than medical treatment. More care has to be taken to ensure that only the correct beam can reach the patient.

• There may be several treatment rooms for one accelerator