radiologic conference

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    RADIOLOGIC CONFERENCE

    Gene Margaret Bernabe

    Internal Medicine

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    Pulmonary Function Tet

    • Mild retricti!e !entilatory de"ect#it$ no igni%cant re&one tobronc$odilator'

    •  T$ere i mild im&airment in gae(c$ange'

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    Bleomycin

    • c$emot$era&eutic agent commonlyued to treat curable dieae uc$a germinati!e tumor and )odg*in+lym&$oma

    • AE, pulmonary toxicity

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    Bleomycin

    bronc$iolitieoino&$ilicintertitial

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    C$et radiogra&$ic Finding

    • bilateral- bibailarin%ltrate

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    )ig$.reolution com&utedtomogra&$y /)RCT0

    • more eniti!e• Di1ue al!eolar

    damage iaociated #it$air&aceconolidation and

    ground.glao&acitie'

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    • Endtage %broi – e(teni!e reticular

    mar*ing- – Traction bronc$iectai-

    and $oneycombing

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    BrochiolitisObliteransOrgani2ing&neumonia

    • mani"et a ground.gla o&acitie in abilateral but aymmetric&attern or by air&ace

    conolidation #it$ aub&leural or&eribronc$ialditribution'

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    Pulmonary Function Tet

    • Reduced carbonmono(ide di1uionca&acity

    • Retricti!e !entilator de"ect

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    • Patient recei!ing Bleomycin.

    containing regimen- age over 40year #a aociated #it$ a 2.3-foldhigher ri* o" &ulmonarycom&lication

    • tage I3 dieae at &reentation /)R4'50

    • cumulati!e doe o" 6788888 I9 /)R7':0  ;'M'O+

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    • Cumulati!e doe o" 6?889 are aloaociated #it$ $ig$er rate o"&ulmonary to(icity

    )'

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     Treatment

    • Prednione at 0.7 - !mg"#g• A"ter ?. #ee* . ta&ered o!er an

    additional

      ?.5 mont$ in accordance #it$ t$e&atient+ condition and clinicalre&one

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     T)AN O9

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