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Flashcard Set Title: "Goljan Rapid Review Images"Study this set online at: http://www.flashcardexchange.com/cards/goljan-rapid-review-images-601157

Mallory bodies. Hyaline

(eosinophilic) inclusions

(arrow) are present in the

cytosol of hepatocytes.

.

A and B, Right-sided Bell's palsy

showing inability to fully close the

eye and drooping of the corner of

the mouth

.

Acid-fast stain of a lung biopsy in

a patient with reactivation

tuberculosis due to

Mycobacterium tuberculosis

.

Acoustic neuroma showing spindle-

shaped cells with alternating dark

and light areas

.

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Bronchopneumonia showingpatchy areas of

consolidation

.

Cerebellum in a patient with rabies

showing Purkinje cells with

intracytoplasmic, eosinophilic inclusions

(arrows) called Negri bodies

.

Common systemic fungal infections. The yeast

form of Cryptococcus neoformans (A) produces

a narrow-based bud (arrow). Coccidioides

immitis (B) has spherules containing

endospores (arrows). Multinucleated giant cells

.

Dependent pitting edema showing depressions

in the skin around the ankle. Pitting edema is

due to an increase in vascular hydrostatic

pressure or a decrease in vascular oncotic

pressure (hypoalbuminemia)

.

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Dermatographism .

Diffuse membranous glomerulonephritis. The

H[amp ]E (hematoxylin [amp ] eosin)-stained

biopsy (A) shows glomerular basement

membranes that are uniformly thickened. There

is no proliferative component. The silver stain

.

Diffuse type of gastric

adenocarcinoma with signet-ring

carcinoma cells (arrows)

.

Electron micrograph of a type II

pneumocyte showing lamellar

body (arrow) containing surfactant

.

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Embryonated eggs of

Enterobius vermicularis .

Metastatic renal cell carcinoma

showing multiple nodular lesions

scattered throughout the lung

parenchyma

.

Fibroadenoma .

Mallory bodies. Hyaline

(eosinophilic) inclusions (arrow)

are present in the cytosol of

hepatocytes

.

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Fatty change of the liver .

Hydronephrosis of the kidney. There is

marked dilation of the renal pelvis and

calyces with thinning of the overlying

cortex and medulla due to compression

atrophy

.

. Left ventricular

hypertrophy .

.Benign prostatic

hyperplasia .

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Intestinal metaplasia of thegastric mucosal epithelium

in chronic gastritis

.

Squamous dysplasia of the cervix,

a precursor of squamous cell

carcinoma..jpg

.

Acute myocardial infarction

(MI) showing coagulation

necrosis.

.

Acute myocardial infarction (MI)

showing a pale infarction of the

posterior wall of the left ventricle

(bottom left)

.

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Hemorrhagic infarction of the lung.There is a roughly wedge-shaped

area of hemorrhage.jpg

.

Dry gangrene of the toes .

Cerebral infarction showing

liquefactive necrosis .

Caseous granuloma showing a central

area of acellular, necrotic material

surrounded by activated macrophages

(epithelioid cells), lymphocytes, and

multiple multinucleated Langhans-type

giant cells

.

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Enzymatic fat necrosis in

acute pancreatitis .

Apoptosis in the epidermis. The arrow

shows a clear space in the epidermis

containing an intensely eosinophilic

staining cell with a small, dense nucleus.

.

Signs of acute inflammation. The patient has

erysipelas of the face due to group A

streptococcus. Signs of acute inflammation that

are present in the photograph include redness

(rubor) and swelling (tumor)

.

Acute inflammation. Histologic

section of lung in

bronchopneumonia showing

sheets of neutrophils with

multilobed nuclei.

.

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Purulent (suppurative) inflammation. The

photograph shows a skin abscess(furuncle) due to Staphylococcus aureus.

Abscesses are pus-filled nodules located

in the dermis.

.

Fibrinous inflammation. The

epicardial surface of the heart is

covered by a shaggy layer of fibrin

material

.

Pseudomembranous inflammation. There

is necrosis and a yellow-colored exudate

covering the mucosal surface of the colon

due to a toxin produced by Clostridium

difficile.

.

Chronic inflammation. This tissue

shows an infiltrate of

predominantly plasma cells (cells

with eccentric nucleus and

perinuclear clearing) and

lymphocytes

.

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Ehlers-Danlos syndrome .

Keloid formation .

Absolute leukocytosis with left shift.

Arrows point to band (stab) neutrophils,

which exhibit prominence of the

azurophilic granules (toxic granulation).

Vacuoles in the cytoplasm represent

phagolysosomes

.

Malar rash in systemic lupus

erythematosus showing the

butterfly-wing distribution

.

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Systemic sclerosis. The tighteningof the skin around the mouth is

caused by excess collagen.

.

Kaposi's sarcoma in HIV.

Skin lesions are raised, red,

and nonpruritic

.

Patient with signs of volume the mucosal

surface of the tongue is dry. Additional

findings on examination were

hypotension, tachycardia, and decreased

skin turgor. (From Forbes C, depletion

.

Electrocardiogram showing

hyperkalemia. Arrows show

peaked T waves, which are a sign

of hyperkalemia.

.

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Coronary artery thrombosis. In this

specially stained cross-section of

a coronary artery, collagen is blue

and the thrombus is red

.

Pulmonary embolus. The main

branches of the pulmonary artery

are occluded with large-caliber

thromboemboli (saddle emboli)

.

Down syndrome. The facial profile

(A) shows a short stature, small

head with small nose and ears.

The hand (B) shows a single

palmar (simian) crease

.

Turner's syndrome is

characterized by a webbed

neck

.

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Black widow spider .

Brown recluse spider .

Kwashiorkor and marasmus. Left, Child with

kwashiorkor, showing dependent pitting edema

involving the lower legs. Right, Child with

marasmus, showing broomstick extremities with

loss of muscle mass and sub

.

Anorexia nervosa .

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Gums showing the effects of

scurvy .

Tubular adenoma (adenomatous

polyp) of the colon showing a

fibrovascular stalk

.

Lipoma showing a well-

circumscribed yellow tumor (A)

containing benign adipose cells

(B)

.

Cystic teratoma of the

ovary, .

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.Figure 8-4 Squamous cell carcinoma.

The many well-differentiated foci ofeosinophilic-staining neoplastic cells

produce keratin in layers (keratin

pearls)..jpg

.

Adenocarcinoma. Irregular

glands infiltrate the stroma .

Osteogenic sarcoma of the distal

femur. The light-colored mass of

tumor in the metaphysis abuts the

epiphyseal plate (arrow)

.

Metastasis to the liver. The liver

contains multiple nodules that

have a depressed central area

(umbilicated)

.

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Basal cell carcinoma(invasive tumor that does

not metastasize)

.

Malignant melanoma. The lesionon the patient's forearm is black, is

multinodular, and has an irregular

border with areas of pale-gray

discoloration

.

Xanthelasma. Yellow, raised

lesions are noted on the

eyelids in both eyes

.

Hyaline arteriolosclerosis .

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Abdominal aortic aneurysm .

Henoch-Schnlein purpura .

Acute myocardial infarction

(day 7) in the posterior wall

of the left ventricle

.

Fibrinous pericarditis. The surface

of the heart is covered by a

shaggy, fibrinous exudate

.

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Left ventricular aneurysm.The bulging aneurysm has a

thin wall of scar tissue

.

Acute rheumatic fever. Uniform,

verrucoid-appearing sterile

vegetations appear along the line

of closure of the mitral valve

.

Mitral valve prolapse. The arrow

shows prolapse of the posterior

mitral leaflet into the left atrium

.

Aortic stenosis .

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Acute bacterial endocarditis .

Myocarditis. The biopsy shows a

lymphocytic infiltrate with

dissolution of myocardial fibers

.

Peripheral blood reticulocytes with supravital

stain (new methylene blueView drug

information). Red blood cells with thread-like

material in the cytosol represent residual RNA

filaments and protein (arrow

.

Peripheral blood smear in iron deficiency

anemia. The enlarged central area of

pallor in the red blood cell (arrow)

indicates a decrease in hemoglobin

synthesis,

.

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Ringed sideroblasts in a bone marrow aspirate.

Dark blue iron granules around the nucleus of

developing normoblasts (arrows) represent iron

trapped within mitochondria and indicate a

defect in mitochondri

.

Peripheral blood with coarse basophilic

stippling of RBCs in lead poisoning. Note

the mature RBC containing numerous

dots representing ribosomes (arrow)

.

Peripheral blood in megaloblastic

anemia showing the

hypersegmented neutrophil

(arrow) with nine lobes

.

Peripheral blood with spherocytes in hereditary

spherocytosis. Numerous, round, dense red

blood cells (RBCs) without central areas of

pallor represent spherocytes (arrows). The

mean corpuscular hemoglobi

.

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Leukoerythroblastic reaction.

Numerous bone marrow

reticulocytes with a blue

discoloration

.

Peripheral blood with atypical

lymphocyte. The cell shows prominent

nucleoli and coarse nuclear chromatin.

The cytoplasm is abundant and is

indented by adjacent red blood cells

.

Peripheral blood in chronic myelogenous

leukemia. Marked leukocytosis shows

neutrophils at different stages of development

(segmented and band neutrophils,

metamyelocytes and myelocytes)

.

Peripheral blood with

promyelocyte filled with Auer rods

in acute promyelocytic leukemia

.

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Peripheral blood in chronic

lymphocytic leukemia .

Gaucher disease .

Niemann-Pick disease .

Senile purpura .

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Laryngeal squamous cell

carcinoma .

Asbestos body .

Malignant mesothelioma .

Sarcoid granuloma .

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Chest radiograph in

emphysema .

Primary lung cancer .

Small cell carcinoma of the

lung .

Oral thrush .

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Hairy leukoplakia along the

lateral. .

Leukoplakia of the tongue .

.Barrett's esophagus .

. Esophageal varices .

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. Gastric adenocarcinoma .

.Entamoeba histolytica

trophozoites .

. Celiac disease .

.Dermatitis herpetiformis .

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Hemorrhagic infarction .

. Meckel diverticulum .

. Sigmoid diverticulosis .

. Ulcerative colitis. .

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. Crohn's disease .

Tubular adenoma .

. Familial polyposis .

. Acute appendicitis .

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. Centrilobular hemorrhagic

necrosis .

Alcoholic cirrhosis .

. Spider angioma

(telangiectasia) .

.Kayser-Fleischer ring. .

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.Hepatocellular carcinoma .

. Yellow cholesterol stones .

.Black pigmented stones .

. Adult polycystic kidney

disease .

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Normal glomerulus .

.Subepithelial

immunocomplex .

.Red blood cell cast in the

urine .

. Crescentic

glomerulonephritis .

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. Fatty cast under

polarization .

. Diabetic

glomerulosclerosis .

.Acute pyelonephritis. .

.Waxy cast in the urine

sediment .

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. Benign nephrosclerosis .

.Renal cell carcinoma .

Benign prostatic hyperplasia .

.Prostate cancer. Arrow .

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A, Candida.

B, Chlamydia trachomatis. C,

Gardnerella vaginalis. D,

Herpes type

E, Herpes type 2.

F, Human papillomavirus.

.

G, Neisseria gonorrhoeae.

H, Treponema pallidum.

I, Treponema pallidum.

J, Trichomonas vaginalis.

.

.Extramammary Paget's

disease .

.Squamous cell carcinoma

of cervix .

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.Polycystic ovarian

syndrome .

.Simple hyperplasia of

endometria.jpg .

. Endometrial carcinoma .

.Leiomyomas. .

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. Ruptured ectopic tubal

pregnancy .

.Complete hydatidiform

mole .

.Ductal carcinoma in situ

(DCIS) .

.Lobular carcinoma in situ .

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.Infiltrating ductal

carcinoma. .

.Paget's disease of the

breast .

.Acromegaly showing the

patient .

. Primary hypothyroidism .

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Graves' disease .

Papillary carcinoma of

thyroid. .

.Patient with Cushing

syndrome .

.Osteoporosis of vertebral

column .

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.Rheumatoid arthritis .

.Tophi (arrows) .

.Erythema chronicum

migrans .

.Verruca vulgaris (common

wart) .

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.Molluscum contagiosum .

.Erythema infectiosum .

.Varicella infection of skin .

Impetigo of the face .

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. Patient with severe facial

acne .

.Acne rosacea .

. Tinea versicolor. .

. Lymphocutaneous

sporotrichosis .

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.Contact dermatitis. .

.Actinic (solar) keratosis .

Lichen planus showing flat-

topped .

.Psoriasis involving the

elbow .

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.Nail changes in psoriasis .

. Pityriasis rosea .

. Erythema multiforme .

. Erythema nodosum .

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. Granuloma annulare. .

. Acanthosis nigricans .

.Solar lentigo .

. Seborrheic keratosis on

the breast .

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. Compound nevus .

.Lentigo maligna melanoma .

.Anencephaly .

. Neurofibromatosis .

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.Epidural hematoma .

.Subdural hematoma .

.Atherosclerotic stroke. .

.Embolic stroke .

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. Intracerebral hemorrhage .

.Bacterial meningitis .

. Cerebral abscess .

.Fusion of the podocytes. Arrowheads show

fusion of the podocytes, which should be

separated by slit pores. This finding occurs in all

glomerular diseases that present with the

nephrotic syndrome (e.g., minimal change

.

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.Gram stain of Streptococcus

pneumoniae. The sputum stain

shows numerous lancet-shaped

diplococci

.

.Granular immunofluorescence. Granular

irregular deposits in the capillaries are

caused by immunocomplex deposition

(e.g., poststreptococcal

glomerulonephritis

.

. brain of a newborn with

kernicterus. Arrows depict yellow

bilirubin pigment deposited in the

basal ganglia

.

.Herpes zoster .

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.Huntington disease. Coronal section (A)

shows a dilated lateral ventricle andatrophy of the caudate, putamen, and

globus pallidus when compared with a

normal coronal section (B)

.

.If the crystal is blue when parallel

to the slow ray, the crystal

demonstrates positive

birefringence.

.

.Normal peripheral blood smear showing

RBCs. The RBCs are uniform in size, and

the central areas of pallor are slightly less

than half the total diameter of an RBC.

The four dark objects (arrows) outside

.

. Giardia lamblia with two

nuclei .

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. Man with ankylosing

spondylitis .

.Keratoacanthoma .

classic Reed-Sternberg (RS) cell. The large,

multilobed cell with prominent nucleoli is

surrounded by a halo of clear nucleoplasm.

Classic RS cells are more easily found in mixed-

cellularity Hodgkin's lymphoma

.

.Linear immunofluorescence. The uninterrupted

smooth immunofluorescence along the

glomerular basement membrane is caused by

deposition of IgG antibodies directed against

the membrane (e.g., Goodpasture syndrome)

.

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.Liver biopsy stained with Prussianblue in a patient with hereditary

hemochromatosis

.

.Lung biopsy stained with Gomori

methenamine-silver showing

septated hyphae and fruiting body

(inset) of Aspergillus fumigatus

.

.Malignant plasma cells in multiple

myeloma. The majority of malignant

plasma cells show a gray-blue cytoplasm,

peripherally located nuclei, and

perinuclear clearing

.

.Multiple sclerosis showing

multiple areas of demyelinated

white matter (arrows pointing to

brown plaques)

.

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analgesic nephropathyshowing multiple brownish

necrotic papillae (arrows)

.

.Neonatal respiratory

distress syndrome .

.Neurocysticercosis showing

multiple cysts between the gray

and white matter

.

.Optic disk with papilledema

showing loss of the disk margin

and hard exudates (white streaks

.

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.Osteoarthritis. Bonyprotuberances (Heberden's

nodes)

.

.Patient with myasthenia gravisshowing ptosis of the left eye (A)

followed by opening of the eye (B)

after intravenous injection of

Tensilon.

.

.Petechiae in idiopathic

thrombocytopenic purpura

showing pinpoint hemorrhages, a

sign of platelet dysfunction

.

.Pneumocystis jiroveci pneumonia.

This silver-impregnated cytologic

smear

.

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.Poststreptococcal diffuseproliferative

glomerulonephritis

.

.Potassium hydroxide preparation

of skin scrapings showing hyphae

and yeasts

.

.Prostate cancer metastatic to the

vertebral column. Multiple white

foci of metastatic prostate cancer

produce an osteoblastic response

in the bone.

.

.Radiograph of a skull showing

multiple punched out lytic lesions

in multiple myeloma

.

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.Radiograph showing small

bowel obstruction. .

.Saddle embolus occluding

the main branches of the

pulmonary artery

.

.Senile plaque (arrow) shows an

eosinophilic center with

peripherally located distended

neuronal processes (neurites).

.

.Silver stain showing

Helicobacter pylori

organisms.

.

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.Spongiform encephalopathy in

Creutzfeldt-Jakob disease

showing classic bubbles and holes

of the neuropil cell bodies

.

.Subendothelial immunocomplex

deposits viewed with electron

microscopy.

.

.Substantia nigra in a patient with

Parkinson disease (A) and a

normal individual (B)

.

.Tinea capitis due to

Trichophyton tonsurans .

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cytomegalovirus. The enlarged

nuclei of many of the type I

pneumocytes contain large

inclusions

.

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