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Refences literature survey1. Ragwa,M.F.; Mohamed,A.; Etman,H. Nada; Abd El Azeem R. Ebian; Formulation and invitro Evaluation of Salbutamol Sulphate In Situ Gelling Nasal Inserts. AAPS Pharm. SciTech. 2013,14, (2),712-718.2. Bertram U, Bodmeier R. Parameters affecting the drug release from insitu gelling nasal inserts. Eur. J. Pharm. Biopharm. 2006,63, 310-319.